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$50+ Cheap flights from O'Hare Intl (ORD) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — CHS
Apr 20 — Apr 271
Sun 4/20
Sun 4/27
1 adult, Economy
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Cheap flight deals from O'Hare Intl to South Carolina

Keep the following information in mind while searching for O'Hare Intl to South Carolina flight deals. Data was last updated April 15, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$100
(Cheapflightsfares)

One-way from

$50
(Cheapflightsfares)

Popular in

November

Cheapest in

September

Average price

$324

Good round-trip deal

$152 or less

Good one-way deal

$54 or less
Provider with most accurate pricing for Chicago (CHI)-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Myrtle Beach Intl flights.
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From Chicago O'Hare Intl to South Carolina
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One-way flight from Chicago O'Hare Intl to South Carolina
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Highest demand for flights based on searches. 21% potential increase in price ($78 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Chicago O'Hare Intl to South Carolina.
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Price to beat on a one-way flight from Chicago O'Hare Intl to South Carolina.
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Find flight deals from O'Hare Intl to South Carolina

Cheapest flights from O'Hare Intl to South Carolina
Explore the most affordable flight options available from O'Hare Intl to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/122:19 pmORD - MYR
Nonstop1h 58mSpirit Airlines
Sat 5/1711:32 amMYR - ORD
Nonstop2h 10mSpirit Airlines
Deal found 4/14$100
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/65:36 amORD - CLT
1 stop10h 02mMultiple Airlines
Fri 5/912:01 pmCLT - ORD
Nonstop2h 33mMultiple Airlines
Deal found 4/14$148
This Cheapflightsfares deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1312:41 pmORD - CLT
1 stop8h 19mSpirit Airlines
Thu 5/156:00 amCLT - ORD
1 stop11h 03mSpirit Airlines
Deal found 4/14$149
This CheapOair deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/97:55 amORD - CLT
Nonstop2h 16mFrontier
Sun 5/1112:01 pmCLT - ORD
Nonstop2h 33mFrontier
Deal found 4/14$152
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/118:35 amORD - CLT
Nonstop1h 59mAmerican Airlines
Wed 6/112:38 pmCLT - ORD
Nonstop2h 10mAmerican Airlines
Deal found 4/14$172
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/206:10 pmORD - CLT
Nonstop2h 11mUnited Airlines
Tue 5/276:30 amCLT - ORD
Nonstop2h 18mUnited Airlines
Deal found 4/15$178
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2010:34 amORD - AGS
1 stop6h 26mAmerican Airlines
Tue 5/276:30 pmAGS - ORD
1 stop6h 41mAmerican Airlines
Deal found 4/14$197
This Mytrip deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/912:41 pmORD - SAV
1 stop9h 32mMultiple Airlines
Mon 5/1212:34 pmSAV - ORD
1 stop21h 16mMultiple Airlines
Deal found 4/15$209
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/74:25 pmORD - MYR
1 stop4h 10mDelta
Sat 6/1412:30 pmMYR - ORD
1 stop7h 40mDelta
Deal found 4/14$217
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/229:00 amORD - CLT
1 stop5h 53mDelta
Tue 5/272:21 pmCLT - ORD
1 stop5h 27mDelta
Deal found 4/15$217
This Mytrip deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/129:28 pmORD - MYR
1 stop21h 27mMultiple Airlines
Mon 6/165:15 amMYR - ORD
1 stop26h 22mMultiple Airlines
Deal found 4/15$220
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1711:05 amORD - GSP
1 stop5h 58mDelta
Sun 5/185:30 amGSP - ORD
1 stop3h 59mDelta
Deal found 4/15$223

Cheapflights Fare Finder

Customize your flight search to find flights from O'Hare Intl to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to South Carolina that are best for you.

Fly from

O'Hare Intl

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Mon 5/12

2:19 pm-5:17 pm

Nonstop1h 58m

Myrtle Beach Intl

Sat 5/17

11:32 am-12:42 pm

Nonstop2h 10m

$100

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Tue 5/6

5:36 am-4:38 pm

1 stop10h 02m

Charlotte Douglas

Fri 5/9

12:01 pm-1:34 pm

Nonstop2h 33m

$148

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Tue 5/13

12:41 pm-10:00 pm

1 stop8h 19m

Charlotte Douglas

Thu 5/15

6:00 am-4:03 pm

1 stop11h 03m

$149

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Fri 5/9

7:55 am-11:11 am

Nonstop2h 16m

Charlotte Douglas

Sun 5/11

12:01 pm-1:34 pm

Nonstop2h 33m

$152

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Wed 6/11

8:35 am-11:34 am

Nonstop1h 59m

Charlotte Douglas

Wed 6/11

2:38 pm-3:48 pm

Nonstop2h 10m

$172

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Tue 5/20

6:10 pm-9:21 pm

Nonstop2h 11m

Charlotte Douglas

Tue 5/27

6:30 am-7:48 am

Nonstop2h 18m

$178

ChicagoAugusta

ORD - AGS

ORDAGS

Chicago O'Hare Intl

Tue 5/20

10:34 am-6:00 pm

1 stop6h 26m

Augusta Bush Field

Tue 5/27

6:30 pm-12:11 am

1 stop6h 41m

$197

ChicagoSavannah

ORD - SAV

ORDSAV

Chicago O'Hare Intl

Fri 5/9

12:41 pm-11:13 pm

1 stop9h 32m

Savannah/Hilton Head

Mon 5/12

12:34 pm-8:50 am

1 stop21h 16m

$209

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Sat 6/7

11:05 am-4:33 pm

1 stop4h 28m

Myrtle Beach Intl

Sat 6/14

12:30 pm-7:10 pm

1 stop7h 40m

$217

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 5/22

9:00 am-3:53 pm

1 stop5h 53m

Charlotte Douglas

Tue 5/27

2:21 pm-6:48 pm

1 stop5h 27m

$217

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/14

Showing 1-10 of 60 results
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Best time to book a flight from O'Hare Intl to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to South Carolina

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to South Carolina (average of $217). Flying from Chicago O'Hare Intl Airport to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ORD to SC?

Find hourly flight availability from O'Hare Intl to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 15, 2025.

When flying from Chicago O'Hare Intl Airport to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Chicago O'Hare Intl Airport to South Carolina

Explore weekly flight availability from O'Hare Intl to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 15, 2025.

The most flights from ORD to USSC are scheduled on a Monday (15 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (9 on average).

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 15, 2025.
See what other customers who have flown with Southwest, Delta and Avelo Airlines from Chicago to South Carolina have to say. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,279 reviews

Crew

8.6

Boarding

8.2

Food

7.1

Entertainment

7.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,279 reviews
Southwest
8.0
Very good
4,279 reviews

Crew

8.6

Boarding

8.2

Food

7.1

Entertainment

7.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,918 reviews
Southwest
8.0
Very good
4,279 reviews

Crew

8.6

Boarding

8.2

Food

7.1

Entertainment

7.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Avelo Airlines
7.5
Good
Southwest
8.0
Very good
4,279 reviews

Crew

8.6

Boarding

8.2

Food

7.1

Entertainment

7.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,658 reviews
Southwest
8.0
Very good
4,279 reviews

Crew

8.6

Boarding

8.2

Food

7.1

Entertainment

7.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
JetBlue
7.3
Good
2,927 reviews
Southwest
8.0
Very good
4,279 reviews

Crew

8.6

Boarding

8.2

Food

7.1

Entertainment

7.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Chicago O'Hare Intl Airport to South Carolina one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $50. Users have also found prices from $70 and $81 on Frontier and American Airlines, respectively.

  • What are the most popular routes from Chicago O'Hare Intl Airport to South Carolina?

    The most popular route from Chicago O'Hare Intl Airport to South Carolina is Chicago O'Hare Intl - Charleston. You may also consider Chicago O'Hare Intl - Charlotte Douglas or Chicago O'Hare Intl - Savannah/Hilton Head.

  • What are the most reliable airlines from Chicago O'Hare Intl Airport to South Carolina?

    The top 3 most reliable airlines when flying from Chicago O'Hare Intl Airport to South Carolina are Lufthansa (87%), Emirates (85%) and Republic Airways (84%).

  • What are the cheapest flights from Chicago O'Hare Intl Airport to South Carolina?

    Looking at all options, your cheapest flight can be booked for $134. While the most popular route (Chicago O'Hare Intl - Charleston) can be booked for $161 on average our data indicates $506 when flying from Chicago O'Hare Intl Airport to South Carolina.

  • Can I find deals for flights from O'Hare Intl to South Carolina that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to South Carolina.

  • Can I find deals for business class flights from O'Hare Intl to South Carolina?

    Yes. Cheapflights offers flight deals from O'Hare Intl to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to South Carolina (average of $217). Flying from Chicago O'Hare Intl Airport to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for O'Hare Intl to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from O'Hare Intl to South Carolina

Discover the top 5 airlines that operate flights from O'Hare Intl to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$69Average$167FlexibilityNo cancel feeOn-time65%
DeltaCheapest$133Average$322FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$160Average$404FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$209Average$372FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$236Average$394FlexibilityNo cancel feeOn-time63%

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