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$39+ Cheap flights from Chicago (CHI) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — CHS
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
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Cheap flight deals from Chicago to South Carolina

Keep the following information in mind while searching for Chicago to South Carolina flight deals. Data was last updated March 31, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$128
(SmartFares)

One-way from

$39
(Kiwi.com)

Popular in

November

Cheapest in

September

Average price

$396

Good round-trip deal

$189 or less

Good one-way deal

$135 or less
Provider with most accurate pricing for Chicago (CHI)-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Myrtle Beach Intl flights.
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From Chicago (CHI) to South Carolina
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One-way flight from Chicago (CHI) to South Carolina
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Highest demand for flights based on searches. 22% potential increase in price ($83 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Price to beat on a round-trip flight from Chicago (CHI) to South Carolina.
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Price to beat on a one-way flight from Chicago (CHI) to South Carolina.
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Find flight deals from Chicago to South Carolina

Cheapest flights from Chicago to South Carolina
Explore the most affordable flight options available from Chicago to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/87:47 amORD - MYR
1 stop10h 38mSpirit Airlines
Sat 5/1711:32 amMYR - ORD
Nonstop2h 10mSpirit Airlines
Deal found 3/31$122
This Cheapflightsfares deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/155:36 amORD - CLT
1 stop10h 02mSpirit Airlines
Fri 4/184:20 pmCLT - ORD
1 stop6h 06mSpirit Airlines
Deal found 3/30$128
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/306:51 amORD - CLT
1 stop7h 34mMultiple Airlines
Sun 5/412:01 pmCLT - ORD
Nonstop2h 33mMultiple Airlines
Deal found 3/30$136
This CheapOair deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/27:59 amORD - CLT
Nonstop2h 08mFrontier
Sun 5/412:01 pmCLT - ORD
Nonstop2h 33mFrontier
Deal found 3/31$142
This Frontier deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/19:51 amMDW - CLT
1 stop10h 55mFrontier
Fri 5/210:36 amCLT - MDW
1 stop10h 57mFrontier
Deal found 3/31$158
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/28:35 amMDW - SAV
Nonstop2h 09mAllegiant Air
Mon 5/126:30 amSAV - MDW
Nonstop2h 15mAllegiant Air
Deal found 3/30$166
This Southwest deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/126:45 pmMDW - CLT
Nonstop1h 50mSouthwest
Wed 5/146:40 pmCLT - MDW
Nonstop2h 15mSouthwest
Deal found 3/31$197
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1310:34 amORD - CLT
Nonstop2h 07mAmerican Airlines
Tue 5/208:30 pmCLT - ORD
Nonstop2h 13mAmerican Airlines
Deal found 3/30$197
This Booking.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/303:16 pmMDW - SAV
Nonstop2h 05mMultiple Airlines
Mon 6/23:12 pmSAV - MDW
1 stop5h 40mMultiple Airlines
Deal found 3/30$207
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/136:00 amMDW - CLT
1 stop6h 36mDelta
Tue 5/2011:24 amCLT - MDW
1 stop4h 56mDelta
Deal found 3/30$217
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/137:10 amORD - CLT
1 stop4h 01mDelta
Tue 5/202:21 pmCLT - ORD
1 stop5h 27mDelta
Deal found 3/30$217
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1011:37 amORD - CAE
1 stop5h 59mAmerican Airlines
Sat 5/174:19 pmCAE - ORD
1 stop4h 16mAmerican Airlines
Deal found 3/30$224

Cheapflights Fare Finder

Customize your flight search to find flights from Chicago to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from Chicago to South Carolina that are best for you.

Fly from

Chicago

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Thu 5/8

7:47 am-7:25 pm

1 stop10h 38m

Myrtle Beach Intl

Sat 5/17

11:32 am-12:42 pm

Nonstop2h 10m

$122

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Tue 4/15

5:36 am-4:38 pm

1 stop10h 02m

Charlotte Douglas

Fri 4/18

4:20 pm-9:26 pm

1 stop6h 06m

$128

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Wed 4/30

6:51 am-3:25 pm

1 stop7h 34m

Charlotte Douglas

Sun 5/4

12:01 pm-1:34 pm

Nonstop2h 33m

$136

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Fri 5/2

7:59 am-11:07 am

Nonstop2h 08m

Charlotte Douglas

Sun 5/4

12:01 pm-1:34 pm

Nonstop2h 33m

$142

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 5/1

9:51 am-9:46 pm

1 stop10h 55m

Charlotte Douglas

Mon 5/5

10:46 am-8:33 pm

1 stop10h 47m

$158

ChicagoSavannah

MDW - SAV

MDWSAV

Chicago Midway

Fri 5/2

8:35 am-11:44 am

Nonstop2h 09m

Savannah/Hilton Head

Mon 5/12

6:30 am-7:45 am

Nonstop2h 15m

$166

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Mon 5/12

6:45 pm-9:35 pm

Nonstop1h 50m

Charlotte Douglas

Wed 5/14

6:40 pm-7:55 pm

Nonstop2h 15m

$197

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Tue 5/13

10:34 am-1:41 pm

Nonstop2h 07m

Charlotte Douglas

Tue 5/20

8:30 pm-9:43 pm

Nonstop2h 13m

$197

ChicagoSavannah

MDW - SAV

MDWSAV

Chicago Midway

Fri 5/30

3:16 pm-6:21 pm

Nonstop2h 05m

Savannah/Hilton Head

Mon 6/2

3:12 pm-7:52 pm

1 stop5h 40m

$207

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Tue 5/13

6:00 am-1:36 pm

1 stop6h 36m

Charlotte Douglas

Tue 5/20

11:24 am-3:20 pm

1 stop4h 56m

$217

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 60 results
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Best time to book a flight from Chicago to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to South Carolina

What is the cheapest month to book a flight from Chicago to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Chicago to South Carolina (average of $217). Flying from Chicago to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to SC?

Find hourly flight availability from Chicago to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

When flying from Chicago to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Chicago to South Carolina

Explore weekly flight availability from Chicago to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 31, 2025.

The most flights from CHI to USSC are scheduled on a Monday (16 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (9 on average).

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 31, 2025.
Get a feel of what it's like to fly with Southwest, Delta and Avelo Airlines from Chicago to South Carolina by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,276 reviews

Comfort

8.0

Crew

8.6

Entertainment

7.6

Food

7.1

Overall

8.0

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,276 reviews
Southwest
8.0
Very good
4,276 reviews

Comfort

8.0

Crew

8.6

Entertainment

7.6

Food

7.1

Overall

8.0

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,899 reviews
Southwest
8.0
Very good
4,276 reviews

Comfort

8.0

Crew

8.6

Entertainment

7.6

Food

7.1

Overall

8.0

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Avelo Airlines
7.5
Good
Southwest
8.0
Very good
4,276 reviews

Comfort

8.0

Crew

8.6

Entertainment

7.6

Food

7.1

Overall

8.0

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,614 reviews
Southwest
8.0
Very good
4,276 reviews

Comfort

8.0

Crew

8.6

Entertainment

7.6

Food

7.1

Overall

8.0

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
JetBlue
7.3
Good
2,924 reviews
Southwest
8.0
Very good
4,276 reviews

Comfort

8.0

Crew

8.6

Entertainment

7.6

Food

7.1

Overall

8.0

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Chicago to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Chicago to South Carolina one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $39. Users have also found prices from $62 and $78 on Allegiant Air and Frontier, respectively.

  • What are the most popular routes from Chicago to South Carolina?

    When deciding which route to take from Chicago to South Carolina consider Chicago O'Hare Intl - Charleston, Chicago O'Hare Intl - Charlotte Douglas or Chicago O'Hare Intl - Savannah/Hilton Head as they are the most popular.

  • What are the most reliable airlines from Chicago to South Carolina?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Chicago to South Carolina on time: Lufthansa (87%), Emirates (87%), Envoy Air (86%).

  • What are the cheapest flights from Chicago to South Carolina?

    On average you can expect to pay $591 for a flight from Chicago to South Carolina. The cheapest flight overall is $134 while the most popular route, (Chicago O'Hare Intl - Charleston) is currently priced at $185.

  • Can I find deals for flights from Chicago to South Carolina that include hotel bookings?

    Yes. In addition to deals on Chicago to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to South Carolina.

  • Can I find deals for business class flights from Chicago to South Carolina?

    Yes. Cheapflights offers flight deals from Chicago to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Chicago to South Carolina (average of $217). Flying from Chicago to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Chicago to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Chicago to South Carolina

Discover the top 5 airlines that operate flights from Chicago to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$79Average$168FlexibilityNo cancel feeOn-time65%
DeltaCheapest$133Average$384FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$169Average$409FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$209Average$372FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$236Average$382FlexibilityNo cancel feeOn-time63%
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