HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$46+ Cheap flights from Chicago (CHI) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — CHS
Jan 26 — Feb 21
Sun 1/26
Sun 2/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Chicago to South Carolina with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Chicago to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$119
(Frontier)

One-way from

$46
(FlightHub)

Good round-trip deal

$279 or less

Good one-way deal

$174 or less
From Chicago (CHI) to South Carolina
Search Deals
One-way flight from Chicago (CHI) to South Carolina
Search Deals
Price to beat on a round-trip flight from Chicago (CHI) to South Carolina.
Search Deals
Price to beat on a one-way flight from Chicago (CHI) to South Carolina.
Search Deals

Find flight deals from Chicago to South Carolina

Cheapest flights from Chicago to South Carolina
Explore the most affordable flight options available from Chicago to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This Frontier deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/287:18 pmORD - CLT
1 stop10h 50mFrontier
Mon 3/39:46 pmCLT - ORD
1 stop13h 05mFrontier
Deal found 1/20$119
This Frontier deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/77:15 amMDW - CLT
1 stop7h 53mFrontier
Mon 2/1012:46 pmCLT - MDW
1 stop10h 53mFrontier
Deal found 1/20$120
This Cheapflightsfares deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/2512:25 pmORD - CLT
1 stop6h 25mSpirit Airlines
Tue 1/286:07 pmCLT - ORD
1 stop5h 48mSpirit Airlines
Deal found 1/19$120
This CheapOair deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2712:59 pmORD - CLT
Nonstop2h 10mMultiple Airlines
Sun 3/27:17 amCLT - ORD
1 stop6h 20mMultiple Airlines
Deal found 1/20$124
This Cheapflightsfares deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/1512:31 pmORD - MYR
1 stop8h 33mSpirit Airlines
Wed 3/196:30 amMYR - ORD
1 stop5h 45mSpirit Airlines
Deal found 1/21$145
This Southwest deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/188:40 amMDW - CLT
Nonstop1h 55mSouthwest
Tue 2/256:20 amCLT - MDW
Nonstop2h 00mSouthwest
Deal found 1/21$157
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/46:00 pmORD - CLT
Nonstop2h 02mUnited Airlines
Mon 3/1010:46 amCLT - ORD
Nonstop2h 17mUnited Airlines
Deal found 1/20$157
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/44:41 pmORD - CLT
Nonstop1h 53mAmerican Airlines
Wed 3/1211:19 amCLT - ORD
Nonstop2h 13mAmerican Airlines
Deal found 1/20$163
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2010:57 amMDW - CLT
1 stop4h 08mDelta
Thu 2/277:05 amCLT - MDW
1 stop4h 07mDelta
Deal found 1/21$197
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/206:45 amORD - CLT
1 stop4h 19mDelta
Sun 2/234:59 pmCLT - ORD
1 stop4h 54mDelta
Deal found 1/21$197
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/46:15 pmORD - GSP
Nonstop1h 59mUnited Airlines
Tue 3/116:40 amGSP - ORD
Nonstop2h 23mUnited Airlines
Deal found 1/21$219
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/49:38 amORD - CAE
1 stop4h 09mDelta
Tue 3/115:40 amCAE - ORD
1 stop3h 57mDelta
Deal found 1/20$239

Find flights from Chicago to South Carolina within your budget

Customize your flight search to find flights from Chicago to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Fri 2/28

7:18 pm-7:08 am

1 stop10h 50m

Charlotte Douglas

Mon 3/3

9:46 pm-9:51 am

1 stop13h 05m

$119

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 2/7

7:15 am-4:08 pm

1 stop7h 53m

Charlotte Douglas

Mon 2/10

12:46 pm-10:39 pm

1 stop10h 53m

$120

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 2/27

12:59 pm-4:09 pm

Nonstop2h 10m

Charlotte Douglas

Sun 3/2

7:17 am-12:37 pm

1 stop6h 20m

$124

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Tue 2/18

5:15 am-5:36 pm

1 stop11h 21m

Charlotte Douglas

Tue 2/25

4:18 pm-11:58 pm

1 stop8h 40m

$126

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Sun 2/2

5:50 am-3:01 pm

1 stop8h 11m

Myrtle Beach Intl

Thu 2/6

9:11 am-2:32 pm

1 stop6h 21m

$146

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Tue 2/18

8:40 am-11:35 am

Nonstop1h 55m

Charlotte Douglas

Tue 2/25

6:20 am-7:20 am

Nonstop2h 00m

$157

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Tue 3/4

2:00 pm-5:02 pm

Nonstop2h 02m

Charlotte Douglas

Tue 3/11

6:40 am-8:00 am

Nonstop2h 20m

$157

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Tue 3/4

4:41 pm-7:34 pm

Nonstop1h 53m

Charlotte Douglas

Wed 3/12

11:19 am-12:32 pm

Nonstop2h 13m

$163

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Mon 2/24

6:45 am-12:11 pm

1 stop4h 26m

Myrtle Beach Intl

Tue 3/11

2:08 pm-6:55 pm

1 stop5h 47m

$197

ChicagoMyrtle Beach

MDW - MYR

MDWMYR

Chicago Midway

Tue 3/25

3:35 pm-8:35 pm

1 stop4h 00m

Myrtle Beach Intl

Tue 4/1

11:00 am-7:00 pm

1 stop9h 00m

$197

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Chicago to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Chicago to South Carolina

Get recent, data-driven insights about flights from Chicago to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Chicago to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Chicago to South Carolina (average of $217). Flying from Chicago to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to SC?

Find hourly flight availability from Chicago to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

When flying from Chicago to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Chicago to South Carolina

Explore weekly flight availability from Chicago to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 21, 2025.

The most flights from CHI to USSC are scheduled on a Monday (15 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (10 on average).

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 21, 2025.
Get a feel of what it's like to fly with Frontier, Spirit Airlines and Southwest from Chicago to South Carolina by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Boarding

8.2

Crew

8.7

Entertainment

7.7

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,662 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Boarding

8.2

Crew

8.7

Entertainment

7.7

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,521 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Boarding

8.2

Crew

8.7

Entertainment

7.7

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

JetBlue
7.4
Good
3,201 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Boarding

8.2

Crew

8.7

Entertainment

7.7

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,985 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Boarding

8.2

Crew

8.7

Entertainment

7.7

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Allegiant Air
7.4
Good
801 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Boarding

8.2

Crew

8.7

Entertainment

7.7

Overall

8.1

Food

7.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Chicago to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Chicago to South Carolina one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $46. Users have also found prices from $54 and $58 on Frontier and Allegiant Air, respectively.

  • What are the most popular routes from Chicago to South Carolina?

    When deciding which route to take from Chicago to South Carolina consider Chicago O'Hare Intl - Charleston, Chicago O'Hare Intl - Charlotte Douglas or Chicago O'Hare Intl - Savannah/Hilton Head as they are the most popular.

  • What are the most reliable airlines from Chicago to South Carolina?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Chicago to South Carolina on time: SkyWest Airlines (100%), American Airlines (94%), Alaska Airlines (94%).

  • What are the cheapest flights from Chicago to South Carolina?

    On average you can expect to pay $307 for a flight from Chicago to South Carolina. The cheapest flight overall is $144 while the most popular route, (Chicago O'Hare Intl - Charleston) is currently priced at $145.

  • Can I find deals for flights from Chicago to South Carolina that include hotel bookings?

    Yes. In addition to deals on Chicago to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to South Carolina.

  • Can I find deals for business class flights from Chicago to South Carolina?

    Yes. Cheapflights offers flight deals from Chicago to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Chicago to South Carolina (average of $217). Flying from Chicago to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Chicago to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Las Vegas flights
O'Hare Intl to Orlando flights
O'Hare Intl to Sky Harbor Intl flights
O'Hare Intl to Fort Lauderdale flights
O'Hare Intl to Miami flights
O'Hare Intl to John F Kennedy Intl flights
O'Hare Intl to Dallas/Fort Worth flights
O'Hare Intl to Tampa flights
O'Hare Intl to Denver flights
O'Hare Intl to Los Angeles flights
O'Hare Intl to Seattle flights
O'Hare Intl to LaGuardia flights
Midway to Sky Harbor Intl flights
O'Hare Intl to Boston flights
Midway to Las Vegas flights
O'Hare Intl to San Francisco flights
O'Hare Intl to Newark flights
Midway to Orlando flights
Midway to Dallas/Fort Worth flights
O'Hare Intl to Fort Myers flights
O'Hare Intl to Atlanta flights
Midway to Miami flights
O'Hare Intl to New Orleans flights
O'Hare Intl to Honolulu flights
O'Hare Intl to Austin flights
O'Hare Intl to Salt Lake City flights
O'Hare Intl to San Diego flights
Midway to Newark flights
Midway to Los Angeles flights
O'Hare Intl to Nashville flights
O'Hare Intl to West Palm Beach flights
Midway to Atlanta flights
O'Hare Intl to Santa Ana flights
O'Hare Intl to Baltimore flights
O'Hare Intl to Philadelphia flights
Midway to Hobby flights
Midway to Tampa flights
O'Hare Intl to Dulles Intl flights
O'Hare Intl to Sarasota flights
O'Hare Intl to Charleston flights
O'Hare Intl to Reagan-National flights
Midway to John F Kennedy Intl flights
Midway to LaGuardia flights
Midway to Denver flights
O'Hare Intl to Palm Springs flights
St. Louis to Las Vegas flights
O'Hare Intl to Hobby flights
O'Hare Intl to Ontario flights
Midway to Fort Myers flights
Midway to San Francisco flights

Top 5 airlines flying from Chicago to South Carolina

Discover the top 5 airlines that operate flights from Chicago to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$80Average$171FlexibilityNo cancel feeOn-time65%
DeltaCheapest$133Average$411FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$149Average$404FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$209Average$372FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$242Average$410FlexibilityNo cancel feeOn-time63%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.