HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$62+ Cheap flights from Chicago (CHI) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/30. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — CHS
abr. 27 — may. 41
dom. 4/27
dom. 5/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Chicago to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Chicago to South Carolina

Keep the following information in mind while searching for Chicago to South Carolina flight deals. Data was last updated abril 22, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$115
(FlightHub)

One-way from

$62
(Booking.com)

Popular in

November

Cheapest in

September

Average price

$327

Good round-trip deal

$159 or less

Good one-way deal

$54 or less
Provider with most accurate pricing for Chicago (CHI)-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago (CHI)-Myrtle Beach Intl flights.
Search Deals
From Chicago (CHI) to South Carolina
Search Deals
One-way flight from Chicago (CHI) to South Carolina
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($78 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals
Price to beat on a round-trip flight from Chicago (CHI) to South Carolina.
Search Deals
Price to beat on a one-way flight from Chicago (CHI) to South Carolina.
Search Deals

Find flight deals from Chicago to South Carolina

Cheapest flights from Chicago to South Carolina
Explore the most affordable flight options available from Chicago to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 22, 2025.

This FlightHub deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/208:05 amMDW - SAV
Nonstop2h 07mAllegiant Air
vie. 6/276:00 amSAV - MDW
Nonstop2h 15mAllegiant Air
Deal found 4/21$115
This Frontier deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/157:55 amORD - CLT
Nonstop2h 16mFrontier
dom. 5/1812:01 pmCLT - ORD
Nonstop2h 33mFrontier
Deal found 4/22$156
This Cheapflightsfares deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 6/71:59 pmORD - MYR
Nonstop1h 58mSpirit Airlines
sáb. 6/146:00 amMYR - ORD
Nonstop2h 24mSpirit Airlines
Deal found 4/22$159
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/1412:41 pmORD - CLT
1 stop8h 19mMultiple Airlines
vie. 5/1612:01 pmCLT - ORD
Nonstop2h 33mMultiple Airlines
Deal found 4/22$159
This Frontier deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/159:51 amMDW - CLT
1 stop10h 55mFrontier
dom. 5/185:29 pmCLT - MDW
1 stop6h 11mFrontier
Deal found 4/22$160
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/245:00 amORD - CLT
Nonstop2h 07mAmerican Airlines
dom. 5/2510:51 pmCLT - ORD
Nonstop2h 20mAmerican Airlines
Deal found 4/22$161
This Cheapflightsfares deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/1312:41 pmORD - CLT
1 stop8h 19mSpirit Airlines
jue. 5/156:00 amCLT - ORD
1 stop11h 03mSpirit Airlines
Deal found 4/21$163
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/247:45 pmMDW - CLT
Nonstop1h 50mSouthwest
vie. 7/46:35 amCLT - MDW
Nonstop1h 55mSouthwest
Deal found 4/22$174
This Gotogate deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/68:05 amMDW - SAV
Nonstop2h 07mMultiple Airlines
lun. 6/93:12 pmSAV - MDW
1 stop5h 40mMultiple Airlines
Deal found 4/21$190
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/2410:25 amMDW - CLT
1 stop6h 56mDelta
dom. 5/255:40 amCLT - MDW
1 stop5h 00mDelta
Deal found 4/22$197
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/249:45 amORD - CLT
1 stop4h 11mDelta
dom. 5/257:30 amCLT - ORD
1 stop6h 11mDelta
Deal found 4/22$197
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/29:25 amORD - MYR
1 stop6h 19mDelta
vie. 7/45:25 pmMYR - ORD
1 stop7h 34mDelta
Deal found 4/21$199

Cheapflights Fare Finder

Customize your flight search to find flights from Chicago to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 22, 2025.
Use the filters below to find and compare flights from Chicago to South Carolina that are best for you.

Fly from

Chicago

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoSavannah

MDW - SAV

MDWSAV

Chicago Midway

vie. 6/20

8:05 am-11:12 am

Nonstop2h 07m

Savannah/Hilton Head

vie. 6/27

6:00 am-7:15 am

Nonstop2h 15m

$115

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

jue. 5/15

7:55 am-11:11 am

Nonstop2h 16m

Charlotte Douglas

dom. 5/18

12:01 pm-1:34 pm

Nonstop2h 33m

$156

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

sáb. 6/7

1:59 pm-4:57 pm

Nonstop1h 58m

Myrtle Beach Intl

sáb. 6/14

6:00 am-7:24 am

Nonstop2h 24m

$159

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

mié. 5/14

12:41 pm-10:00 pm

1 stop8h 19m

Charlotte Douglas

vie. 5/16

12:01 pm-1:34 pm

Nonstop2h 33m

$159

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

jue. 5/15

9:51 am-9:46 pm

1 stop10h 55m

Charlotte Douglas

dom. 5/18

5:29 pm-10:40 pm

1 stop6h 11m

$160

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

sáb. 5/24

5:00 am-8:07 am

Nonstop2h 07m

Charlotte Douglas

dom. 5/25

10:51 pm-12:11 am

Nonstop2h 20m

$161

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

mar. 5/13

12:41 pm-10:00 pm

1 stop8h 19m

Charlotte Douglas

jue. 5/15

6:00 am-4:03 pm

1 stop11h 03m

$163

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

mar. 6/24

7:45 pm-10:35 pm

Nonstop1h 50m

Charlotte Douglas

vie. 7/4

6:35 am-7:30 am

Nonstop1h 55m

$174

ChicagoSavannah

MDW - SAV

MDWSAV

Chicago Midway

vie. 6/6

8:05 am-11:12 am

Nonstop2h 07m

Savannah/Hilton Head

lun. 6/9

3:12 pm-7:52 pm

1 stop5h 40m

$190

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

sáb. 5/24

10:25 am-6:21 pm

1 stop6h 56m

Charlotte Douglas

dom. 5/25

5:40 am-9:40 am

1 stop5h 00m

$197

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/21

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Chicago to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to South Carolina

What is the cheapest month to book a flight from Chicago to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Chicago to South Carolina (average of $217). Flying from Chicago to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to SC?

Find hourly flight availability from Chicago to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 22, 2025.

When flying from Chicago to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Chicago to South Carolina

Explore weekly flight availability from Chicago to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated abril 22, 2025.

The most flights from CHI to USSC are scheduled on a Monday (16 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (9 on average).

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated abril 22, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Southwest and Delta from Chicago to South Carolina by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,906 reviews

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

7.9

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Alaska Airlines
8.0
Very good
9,906 reviews
Alaska Airlines
8.0
Very good
9,906 reviews

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

7.9

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Southwest
8.0
Very good
4,286 reviews
Alaska Airlines
8.0
Very good
9,906 reviews

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

7.9

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Delta
8.0
Very good
7,920 reviews
Alaska Airlines
8.0
Very good
9,906 reviews

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

7.9

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Avelo Airlines
7.5
Good
Alaska Airlines
8.0
Very good
9,906 reviews

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

7.9

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
United Airlines
7.4
Good
8,683 reviews
Alaska Airlines
8.0
Very good
9,906 reviews

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

7.9

Entertainment

7.1

Crew

8.5

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Related info for your journey

Find useful and relevant information for your journey from Chicago to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Chicago to South Carolina one-way?

    For one-way options, check prices for Allegiant Air. According to our data, you can fly for as low as $62. Users have also found prices from $72 and $73 on Spirit Airlines and Frontier, respectively.

  • What are the most popular routes from Chicago to South Carolina?

    When deciding which route to take from Chicago to South Carolina consider Chicago O'Hare Intl - Charleston, Chicago O'Hare Intl - Charlotte Douglas or Chicago O'Hare Intl - Savannah/Hilton Head as they are the most popular.

  • What are the most reliable airlines from Chicago to South Carolina?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Chicago to South Carolina on time: Lufthansa (90%), Emirates (86%), Republic Airways (83%).

  • What are the cheapest flights from Chicago to South Carolina?

    On average you can expect to pay $460 for a flight from Chicago to South Carolina. The cheapest flight overall is $139 while the most popular route, (Chicago O'Hare Intl - Charleston) is currently priced at $206.

  • Can I find deals for flights from Chicago to South Carolina that include hotel bookings?

    Yes. In addition to deals on Chicago to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to South Carolina.

  • Can I find deals for business class flights from Chicago to South Carolina?

    Yes. Cheapflights offers flight deals from Chicago to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Chicago to South Carolina (average of $217). Flying from Chicago to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Chicago to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to LaGuardia flights
O'Hare Intl to Dallas/Fort Worth flights
O'Hare Intl to John F Kennedy Intl flights
O'Hare Intl to Las Vegas flights
O'Hare Intl to Los Angeles flights
O'Hare Intl to Newark flights
O'Hare Intl to Seattle flights
O'Hare Intl to Sky Harbor Intl flights
O'Hare Intl to Denver flights
O'Hare Intl to Miami flights
O'Hare Intl to Orlando flights
Midway to John F Kennedy Intl flights
O'Hare Intl to San Francisco flights
Midway to Newark flights
Midway to Las Vegas flights
O'Hare Intl to Boston flights
O'Hare Intl to Fort Lauderdale flights
O'Hare Intl to San Diego flights
O'Hare Intl to Hobby flights
O'Hare Intl to Atlanta flights
O'Hare Intl to New Orleans flights
O'Hare Intl to San Antonio flights
O'Hare Intl to Tampa flights
St. Louis to Seattle flights
O'Hare Intl to Honolulu flights
O'Hare Intl to Philadelphia flights
O'Hare Intl to George Bush Intcntl flights
O'Hare Intl to Dulles Intl flights
O'Hare Intl to Austin flights
Midway to Dallas/Fort Worth flights
O'Hare Intl to Santa Ana flights
O'Hare Intl to Reagan-National flights
O'Hare Intl to Portland flights
O'Hare Intl to Nashville flights
O'Hare Intl to Baltimore flights
O'Hare Intl to Salt Lake City flights
O'Hare Intl to Charleston flights
Midway to Sky Harbor Intl flights
Midway to Atlanta flights
O'Hare Intl to Charlotte flights
O'Hare Intl to Savannah flights
O'Hare Intl to Raleigh flights
St. Louis to Las Vegas flights
Midway to LaGuardia flights
O'Hare Intl to Anchorage flights
Midway to Los Angeles flights
O'Hare Intl to Fort Myers flights
O'Hare Intl to Burbank flights
Midway to San Francisco flights
O'Hare Intl to Ontario flights

Top 5 airlines flying from Chicago to South Carolina

Discover the top 5 airlines that operate flights from Chicago to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$67Average$166FlexibilityNo cancel feeOn-time65%
DeltaCheapest$133Average$376FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$163Average$403FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$209Average$372FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$236Average$382FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.