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$190+ Cheap flights from Cape Cod and the Islands to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/30. Fares are subject to change and may not be available on all flights or dates of travel.
ACK — CHS
Apr 29 — May 61
Tue 4/29
Tue 5/6
1 adult, Economy
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Cheap flight deals from Cape Cod and the Islands to South Carolina

Keep the following information in mind while searching for Cape Cod and the Islands to South Carolina flight deals. Data was last updated April 24, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$248
(Delta)

One-way from

$200
(American Airlines)

Popular in

April

Cheapest in

February

Average price

$277
Provider with most accurate pricing for Boston Logan Intl-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Boston Logan Intl-Myrtle Beach Intl flights.
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From Cape Cod and the Islands to South Carolina
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One-way flight from Cape Cod and the Islands to South Carolina
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Highest demand for flights based on searches. 14% potential increase in price ($32 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Cape Cod and the Islands to South Carolina

Cheapest flights from Cape Cod and the Islands to South Carolina
Explore the most affordable flight options available from Cape Cod and the Islands to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/64:56 pmMVY - CHS
1 stop5h 20mDelta
Mon 6/97:00 amCHS - MVY
1 stop6h 36mDelta
Deal found 4/23$248
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2212:15 pmMVY - CLT
1 stop7h 04mDelta
Mon 5/267:05 amCLT - MVY
1 stop4h 27mDelta
Deal found 4/23$332
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2711:55 amMVY - SAV
1 stop5h 55mDelta
Fri 7/47:10 amSAV - MVY
1 stop6h 26mDelta
Deal found 4/23$406
This JetBlue Airways deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/83:50 pmHYA - CHS
1 stop25h 10mMultiple Airlines
Mon 5/128:45 pmCHS - HYA
1 stop17h 55mMultiple Airlines
Deal found 4/23$530
This JetBlue deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2211:25 amHYA - CHS
1 stop5h 35mJetBlue
Sun 5/2511:12 amCHS - HYA
1 stop5h 23mJetBlue
Deal found 4/22$681
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/64:55 pmACK - CLT
2 stops29h 05mMultiple Airlines
Sat 5/104:46 pmCLT - ACK
2 stops16h 49mMultiple Airlines
Deal found 4/22$815
This JetBlue deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/282:15 pmMVY - CHS
1 stop6h 39mJetBlue
Mon 12/110:20 amCHS - MVY
1 stop6h 50mJetBlue
Deal found 4/23$866

Cheapflights Fare Finder

Customize your flight search to find flights from Cape Cod and the Islands to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
Use the filters below to find and compare flights from Cape Cod and the Islands to South Carolina that are best for you.

Fly from

Cape Cod and the Islands

Fly to

South Carolina

Route

Depart

Return

Price

West TisburyCharleston

MVY - CHS

MVYCHS

West Tisbury Martha's Vineyard

Fri 6/6

4:56 pm-10:16 pm

1 stop5h 20m

Charleston

Mon 6/9

7:00 am-1:36 pm

1 stop6h 36m

$248

West TisburyCharlotte

MVY - CLT

MVYCLT

West Tisbury Martha's Vineyard

Thu 5/22

12:15 pm-7:19 pm

1 stop7h 04m

Charlotte Douglas

Mon 5/26

7:05 am-11:32 am

1 stop4h 27m

$332

West TisburySavannah

MVY - SAV

MVYSAV

West Tisbury Martha's Vineyard

Fri 6/27

11:55 am-5:50 pm

1 stop5h 55m

Savannah/Hilton Head

Fri 7/4

7:10 am-1:36 pm

1 stop6h 26m

$406

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Thu 5/8

3:50 pm-5:00 pm

1 stop25h 10m

Charleston

Mon 5/12

8:45 pm-2:40 pm

1 stop17h 55m

$530

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Thu 5/22

11:25 am-5:00 pm

1 stop5h 35m

Charleston

Sun 5/25

11:12 am-4:35 pm

1 stop5h 23m

$681

NantucketCharlotte

ACK - CLT

ACKCLT

Nantucket Memorial

Tue 5/6

4:55 pm-10:00 pm

2 stops29h 05m

Charlotte Douglas

Sat 5/10

4:46 pm-9:35 am

2 stops16h 49m

$815

NantucketCharlotte

ACK - CLT

ACKCLT

Nantucket Memorial

Sat 8/30

2:55 pm-8:02 am

1 stop17h 07m

$190

West TisburyCharlotte

MVY - CLT

MVYCLT

West Tisbury Martha's Vineyard

Sat 7/12

11:49 am-2:15 pm

Nonstop2h 26m

$200

West TisburySavannah

MVY - SAV

MVYSAV

West Tisbury Martha's Vineyard

Fri 5/23

4:56 pm-11:34 pm

1 stop6h 38m

$203

West TisburyCharlotte

MVY - CLT

MVYCLT

West Tisbury Martha's Vineyard

Sun 5/25

4:56 pm-10:15 pm

1 stop5h 19m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Showing 1-10 of 17 results
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Best time to book a flight from Cape Cod and the Islands to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Cape Cod and the Islands with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cape Cod and the Islands to South Carolina

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 24, 2025.
To help decide which airline to fly from Cape Cod and the Islands to South Carolina, see what other customers have to say about Delta, United Airlines and JetBlue. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,920 reviews
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,685 reviews
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
JetBlue
7.3
Good
2,924 reviews
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Cape Cod and the Islands to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Cape Cod and the Islands to South Carolina one-way?

    $200 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and JetBlue, with prices starting from $203 and $279, respectively.

  • Can I find deals for flights from Cape Cod and the Islands to South Carolina that include hotel bookings?

    Yes. In addition to deals on Cape Cod and the Islands to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cape Cod and the Islands to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cape Cod and the Islands to South Carolina.

  • Can I find deals for business class flights from Cape Cod and the Islands to South Carolina?

    Yes. Cheapflights offers flight deals from Cape Cod and the Islands to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cape Cod and the Islands to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Cape Cod and the Islands to South Carolina (average of $217). Flying from Cape Cod and the Islands to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Cape Cod and the Islands to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Cape Cod and the Islands to South Carolina

Discover the top airline that operate flights from Cape Cod and the Islands to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$263Average$357FlexibilityNo cancel feeOn-time62%

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