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$178+ Cheap flights from Cape Cod and the Islands to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/8. Fares are subject to change and may not be available on all flights or dates of travel.
ACK — CHS
Feb 16 — Feb 231
Sun 2/16
Sun 2/23
1 adult, Economy
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Cheap flight deals from Cape Cod and the Islands to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Cape Cod and the Islands (zzKDT) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 11, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$414
(JetBlue)

One-way from

$178
(Delta)

Popular in

April

Cheapest in

February

Average price

$142
Provider with most accurate pricing for Boston Logan Intl-Myrtle Beach Intl flight deals.
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From Cape Cod and the Islands to South Carolina
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One-way flight from Cape Cod and the Islands to South Carolina
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Highest demand for flights based on searches. 6% potential increase in price ($12 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Cape Cod and the Islands to South Carolina

Cheapest flights from Cape Cod and the Islands to South Carolina
Explore the most affordable flight options available from Cape Cod and the Islands to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2025.

This JetBlue deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/183:50 pmHYA - CHS
1 stop6h 29mJetBlue
Tue 3/256:00 amCHS - HYA
1 stop4h 10mJetBlue
Deal found 2/10$414
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/242:50 pmMVY - CHS
1 stop7h 33mDelta
Mon 5/267:00 amCHS - MVY
1 stop7h 03mDelta
Deal found 2/11$503
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/212:50 pmMVY - SAV
1 stop6h 43mDelta
Sat 6/287:25 amSAV - MVY
1 stop6h 37mDelta
Deal found 2/10$613
This JetBlue deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/155:45 pmMVY - SAV
1 stop5h 00mJetBlue
Mon 3/176:03 amSAV - MVY
1 stop4h 27mJetBlue
Deal found 2/10$639
This JetBlue deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/185:00 pmMVY - CHS
1 stop5h 19mJetBlue
Tue 3/256:00 amCHS - MVY
1 stop3h 50mJetBlue
Deal found 2/10$674
This United deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/67:10 amHYA - CLT
2 stops10h 05mMultiple Airlines
Sun 6/87:00 amCLT - HYA
2 stops11h 03mMultiple Airlines
Deal found 2/10$817
This Mytrip deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/117:37 amEWB - CLT
3 stops30h 08mMultiple Airlines
Mon 3/176:55 amCLT - EWB
3 stops35h 22mMultiple Airlines
Deal found 2/10$895

Find flights from Cape Cod and the Islands to South Carolina within your budget

Customize your flight search to find flights from Cape Cod and the Islands to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Tue 3/18

3:50 pm-10:19 pm

1 stop6h 29m

Charleston

Tue 3/25

6:00 am-10:10 am

1 stop4h 10m

$414

West TisburyCharleston

MVY - CHS

MVYCHS

West Tisbury Martha's Vineyard

Sat 5/24

2:50 pm-10:23 pm

1 stop7h 33m

Charleston

Mon 5/26

7:00 am-2:03 pm

1 stop7h 03m

$503

West TisburySavannah

MVY - SAV

MVYSAV

West Tisbury Martha's Vineyard

Sat 6/21

2:50 pm-9:33 pm

1 stop6h 43m

Savannah/Hilton Head

Sat 6/28

7:25 am-2:02 pm

1 stop6h 37m

$613

West TisburySavannah

MVY - SAV

MVYSAV

West Tisbury Martha's Vineyard

Sat 3/15

5:45 pm-10:45 pm

1 stop5h 00m

Savannah/Hilton Head

Mon 3/17

6:03 am-10:30 am

1 stop4h 27m

$639

West TisburyCharleston

MVY - CHS

MVYCHS

West Tisbury Martha's Vineyard

Tue 3/18

5:00 pm-10:19 pm

1 stop5h 19m

Charleston

Tue 3/25

6:00 am-9:50 am

1 stop3h 50m

$674

HyannisCharlotte

HYA - CLT

HYACLT

Hyannis Barnstable

Fri 6/6

7:10 am-5:15 pm

2 stops10h 05m

Charlotte Douglas

Sun 6/8

7:00 am-6:03 pm

2 stops11h 03m

$817

New BedfordCharlotte

EWB - CLT

EWBCLT

New Bedford Regional

Tue 3/11

7:37 am-1:45 pm

3 stops30h 08m

Charlotte Douglas

Mon 3/17

6:55 am-6:17 pm

3 stops35h 22m

$895

NantucketCharlotte

ACK - CLT

ACKCLT

Nantucket Memorial

Fri 8/8

4:15 pm-6:47 pm

1 stop26h 32m

$178

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Wed 3/26

3:50 pm-10:19 pm

1 stop6h 29m

$247

West TisburyCharlotte

MVY - CLT

MVYCLT

West Tisbury Martha's Vineyard

Thu 8/7

2:50 pm-7:24 pm

2 stops28h 34m

$262

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/11

Showing 1-10 of 17 results
1
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Best time to book a flight from Cape Cod and the Islands to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Cape Cod and the Islands with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Cape Cod and the Islands to South Carolina

Get recent, data-driven insights about flights from Cape Cod and the Islands to South Carolina including ideal travel times, pricing trends, and more.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated February 11, 2025.
To help decide which airline to fly from Cape Cod and the Islands to South Carolina, see what other customers have to say about Delta, JetBlue and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,332 reviews

Food

7.3

Crew

8.5

Comfort

8.0

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,332 reviews
Delta
8.0
Very good
8,332 reviews

Food

7.3

Crew

8.5

Comfort

8.0

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

JetBlue
7.4
Good
3,110 reviews
Delta
8.0
Very good
8,332 reviews

Food

7.3

Crew

8.5

Comfort

8.0

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,332 reviews

Food

7.3

Crew

8.5

Comfort

8.0

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Cape Cod and the Islands to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Cape Cod and the Islands to South Carolina one-way?

    $178 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on JetBlue and American Airlines, with prices starting from $222 and $359, respectively.

  • Can I find deals for flights from Cape Cod and the Islands to South Carolina that include hotel bookings?

    Yes. In addition to deals on Cape Cod and the Islands to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cape Cod and the Islands to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cape Cod and the Islands to South Carolina.

  • Can I find deals for business class flights from Cape Cod and the Islands to South Carolina?

    Yes. Cheapflights offers flight deals from Cape Cod and the Islands to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cape Cod and the Islands to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Cape Cod and the Islands to South Carolina (average of $217). Flying from Cape Cod and the Islands to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Cape Cod and the Islands to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Cape Cod and the Islands to South Carolina

Discover the top airline that operate flights from Cape Cod and the Islands to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$263Average$357FlexibilityNo cancel feeOn-time62%
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