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$53+ Cheap flights from Buffalo (BUF) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — CHS
Jan 21 — Jan 281
Tue 1/21
Tue 1/28
1 adult, Economy
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Cheap flight deals from Buffalo to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 16, 2025.

Round-trip from

$88
(Frontier)

One-way from

$53
(Trip.com)
From Buffalo to South Carolina
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One-way flight from Buffalo to South Carolina
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Find flight deals from Buffalo to South Carolina

Cheapest flights from Buffalo to South Carolina
Explore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 16, 2025.

This Frontier deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/74:26 pmBUF - CLT
Nonstop2h 01mFrontier
Sun 2/98:45 amCLT - BUF
Nonstop1h 50mFrontier
Deal found 1/14$88
This American Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/86:10 amBUF - CLT
Nonstop1h 57mAmerican Airlines
Wed 4/910:28 pmCLT - BUF
Nonstop1h 36mAmerican Airlines
Deal found 1/15$111
This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/56:00 amBUF - CLT
1 stop6h 14mUnited Airlines
Sat 2/89:55 amCLT - BUF
1 stop4h 13mUnited Airlines
Deal found 1/15$191
This American Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/125:21 amBUF - CAE
1 stop4h 34mAmerican Airlines
Wed 2/197:45 amCAE - BUF
1 stop4h 32mAmerican Airlines
Deal found 1/15$199
This American Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/226:00 amBUF - SAV
1 stop4h 37mAmerican Airlines
Wed 2/266:30 amSAV - BUF
1 stop4h 55mAmerican Airlines
Deal found 1/16$199
This JetBlue deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2211:32 amBUF - CHS
1 stop6h 32mJetBlue
Tue 2/255:14 pmCHS - BUF
1 stop7h 14mJetBlue
Deal found 1/16$203
This Delta deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/1012:03 pmBUF - CLT
1 stop3h 53mDelta
Tue 2/115:46 pmCLT - BUF
1 stop6h 31mDelta
Deal found 1/15$207
This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/211:55 pmBUF - CHS
1 stop7h 38mUnited Airlines
Thu 2/277:20 pmCHS - BUF
1 stop4h 24mUnited Airlines
Deal found 1/15$212
This United Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/46:00 amBUF - SAV
1 stop7h 15mUnited Airlines
Mon 2/102:05 pmSAV - BUF
1 stop5h 03mUnited Airlines
Deal found 1/16$214
This Delta deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/156:50 pmBUF - SAV
1 stop5h 14mDelta
Wed 4/165:30 amSAV - BUF
1 stop5h 46mDelta
Deal found 1/15$217
This Delta deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/711:47 amBUF - CHS
1 stop4h 30mDelta
Tue 2/116:24 pmCHS - BUF
1 stop4h 20mDelta
Deal found 1/16$217
This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/85:40 pmBUF - CAE
1 stop6h 49mUnited Airlines
Sat 2/1510:30 amCAE - BUF
1 stop6h 10mUnited Airlines
Deal found 1/15$224

Find flights from Buffalo to South Carolina within your budget

Customize your flight search to find flights from Buffalo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 16, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Fri 2/7

4:26 pm-6:27 pm

Nonstop2h 01m

Charlotte Douglas

Sun 2/9

8:45 am-10:35 am

Nonstop1h 50m

$88

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Tue 4/8

6:10 am-8:07 am

Nonstop1h 57m

Charlotte Douglas

Wed 4/9

10:28 pm-12:04 am

Nonstop1h 36m

$111

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Wed 2/5

6:00 am-12:14 pm

1 stop6h 14m

Charlotte Douglas

Sat 2/8

9:55 am-2:08 pm

1 stop4h 13m

$191

BuffaloColumbia

BUF - CAE

BUFCAE

Buffalo

Wed 2/12

5:21 am-9:55 am

1 stop4h 34m

Columbia Metropolitan

Wed 2/19

7:45 am-12:17 pm

1 stop4h 32m

$199

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Sat 2/22

6:00 am-10:37 am

1 stop4h 37m

Savannah/Hilton Head

Wed 2/26

6:30 am-11:25 am

1 stop4h 55m

$199

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Sat 2/22

11:32 am-6:04 pm

1 stop6h 32m

Charleston

Tue 2/25

5:14 pm-12:28 am

1 stop7h 14m

$203

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Mon 2/10

12:03 pm-3:56 pm

1 stop3h 53m

Charlotte Douglas

Tue 2/11

5:46 pm-12:17 am

1 stop6h 31m

$207

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Fri 2/21

1:55 pm-9:33 pm

1 stop7h 38m

Charleston

Thu 2/27

7:20 pm-11:44 pm

1 stop4h 24m

$212

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Tue 2/4

6:00 am-1:15 pm

1 stop7h 15m

Savannah/Hilton Head

Mon 2/10

2:05 pm-7:08 pm

1 stop5h 03m

$214

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Tue 4/15

6:50 pm-12:04 am

1 stop5h 14m

Savannah/Hilton Head

Wed 4/16

5:30 am-11:16 am

1 stop5h 46m

$217

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/16

Showing 1-10 of 52 results
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Best time to book a flight from Buffalo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Buffalo to South Carolina

Get recent, data-driven insights about flights from Buffalo to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Buffalo to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of $217). Flying from Buffalo to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SC?

Find hourly flight availability from Buffalo to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Buffalo to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 16, 2025.
Read through reviews of airlines operating flights from Buffalo to South Carolina, such as Frontier, American Airlines and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,659 reviews

Comfort

8.1

Entertainment

7.7

Overall

8.1

Food

7.2

Crew

8.7

Boarding

8.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,659 reviews
Southwest
8.1
Very good
4,659 reviews

Comfort

8.1

Entertainment

7.7

Overall

8.1

Food

7.2

Crew

8.7

Boarding

8.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,511 reviews
Southwest
8.1
Very good
4,659 reviews

Comfort

8.1

Entertainment

7.7

Overall

8.1

Food

7.2

Crew

8.7

Boarding

8.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

JetBlue
7.4
Good
3,199 reviews
Southwest
8.1
Very good
4,659 reviews

Comfort

8.1

Entertainment

7.7

Overall

8.1

Food

7.2

Crew

8.7

Boarding

8.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,965 reviews
Southwest
8.1
Very good
4,659 reviews

Comfort

8.1

Entertainment

7.7

Overall

8.1

Food

7.2

Crew

8.7

Boarding

8.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,659 reviews

Comfort

8.1

Entertainment

7.7

Overall

8.1

Food

7.2

Crew

8.7

Boarding

8.2

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to South Carolina?

    Buffalo (BUF) is the airport you will fly out of if you book a flight from Buffalo to South Carolina. It is only a 8.3 mi journey to Buffalo (BUF) from Buffalo’s city center.

  • What are the cheapest airlines to fly from Buffalo to South Carolina one-way?

    The cheapest airlines for a one-way flight from Buffalo to South Carolina are Frontier ($53), American Airlines ($100), and Delta ($109).

  • What are the most popular routes from Buffalo to South Carolina?

    While some choose either Buffalo - Myrtle Beach Intl or Buffalo - Charleston, Buffalo - Charlotte Douglas is the most popular route from Buffalo to South Carolina.

  • Can I find deals for flights from Buffalo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Buffalo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South Carolina.

  • Can I find deals for business class flights from Buffalo to South Carolina?

    Yes. Cheapflights offers flight deals from Buffalo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of $217). Flying from Buffalo to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Buffalo to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Buffalo to South Carolina

Discover the top 5 airlines that operate flights from Buffalo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$175Average$265FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$196Average$399FlexibilityNo cancel feeOn-time71%
DeltaCheapest$198Average$360FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$218Average$396FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$254Average$398FlexibilityNo cancel feeOn-time69%
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