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$100+ Cheap flights from Buffalo (BUF) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — CHS
feb. 25 — mar. 41
mar. 2/25
mar. 3/4
1 adult, Economy
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Cheap flight deals from Buffalo to South Carolina

Keep the following information in mind while searching for Buffalo to South Carolina flight deals. Data was last updated febrero 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$183
(Delta)

One-way from

$100
(American Airlines)

Popular in

April

Cheapest in

September

Average price

$377
Provider with most accurate pricing for Buffalo-Myrtle Beach Intl flight deals.
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From Buffalo to South Carolina
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One-way flight from Buffalo to South Carolina
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Highest demand for flights based on searches. 7% potential increase in price ($28 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Buffalo to South Carolina

Cheapest flights from Buffalo to South Carolina
Explore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 20, 2025.

This JetBlue deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/268:43 amBUF - CHS
1 stop7h 34mJetBlue
mar. 3/185:14 pmCHS - BUF
1 stop7h 09mJetBlue
Deal found 2/19$183
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/185:51 pmBUF - GSP
1 stop4h 09mAmerican Airlines
mié. 3/197:00 amGSP - BUF
1 stop5h 16mAmerican Airlines
Deal found 2/20$199
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/712:40 pmBUF - SAV
1 stop6h 11mAmerican Airlines
lun. 5/128:24 pmSAV - BUF
1 stop3h 51mAmerican Airlines
Deal found 2/19$199
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/12:54 pmBUF - SAV
2 stops9h 03mUnited Airlines
mié. 4/910:11 amSAV - BUF
1 stop4h 33mUnited Airlines
Deal found 2/19$204
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 4/1912:07 pmBUF - SAV
1 stop6h 59mDelta
jue. 4/246:50 pmSAV - BUF
1 stop5h 07mDelta
Deal found 2/19$223
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/185:30 amBUF - HHH
1 stop5h 34mAmerican Airlines
sáb. 3/225:59 pmHHH - BUF
1 stop6h 21mAmerican Airlines
Deal found 2/20$229
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/136:00 amBUF - CLT
1 stop7h 41mAmerican Airlines
jue. 3/134:35 pmCLT - BUF
Nonstop1h 43mAmerican Airlines
Deal found 2/19$231
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/205:51 pmBUF - CAE
1 stop5h 55mAmerican Airlines
jue. 3/275:10 pmCAE - BUF
1 stop5h 36mAmerican Airlines
Deal found 2/20$249
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/65:10 pmBUF - SAV
1 stop7h 00mSouthwest
jue. 4/103:00 pmSAV - BUF
1 stop4h 15mSouthwest
Deal found 2/18$249
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/97:00 amBUF - CHS
1 stop9h 23mDelta
lun. 4/145:25 pmCHS - BUF
1 stop7h 02mDelta
Deal found 2/19$255
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/167:19 pmBUF - CHS
1 stop4h 38mAmerican Airlines
mar. 4/226:28 amCHS - BUF
1 stop5h 55mAmerican Airlines
Deal found 2/19$257
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/206:00 amBUF - CLT
1 stop3h 50mUnited Airlines
dom. 3/236:00 amCLT - BUF
1 stop3h 52mUnited Airlines
Deal found 2/20$264

Find flights from Buffalo to South Carolina within your budget

Customize your flight search to find flights from Buffalo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.

Fly from

Buffalo

Fly to

South Carolina

Route

Depart

Return

Price

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

lun. 3/17

7:48 pm-12:09 pm

1 stop16h 21m

Charleston

jue. 3/27

7:00 am-7:07 pm

1 stop12h 07m

$183

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

sáb. 4/5

11:19 am-6:01 pm

1 stop6h 42m

Charleston

mié. 4/9

5:25 pm-10:00 pm

1 stop4h 35m

$193

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

mar. 3/18

5:51 pm-10:00 pm

1 stop4h 09m

Greenville

mié. 3/19

7:00 am-12:16 pm

1 stop5h 16m

$199

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

mié. 5/7

5:16 am-10:37 am

1 stop5h 21m

Savannah/Hilton Head

lun. 5/12

8:24 pm-12:15 am

1 stop3h 51m

$199

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

mar. 4/1

2:54 pm-11:57 pm

2 stops9h 03m

Savannah/Hilton Head

mié. 4/9

10:11 am-2:44 pm

1 stop4h 33m

$204

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

sáb. 4/19

12:07 pm-7:06 pm

1 stop6h 59m

Savannah/Hilton Head

jue. 4/24

6:50 pm-11:57 pm

1 stop5h 07m

$223

BuffaloHilton Head Island

BUF - HHH

BUFHHH

Buffalo

mar. 3/18

5:30 am-11:04 am

1 stop5h 34m

Hilton Head Island

sáb. 3/22

5:59 pm-12:20 am

1 stop6h 21m

$229

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

jue. 3/13

6:00 am-1:41 pm

1 stop7h 41m

Charlotte Douglas

jue. 3/13

4:35 pm-6:18 pm

Nonstop1h 43m

$231

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

dom. 4/6

5:10 pm-12:10 am

1 stop7h 00m

Savannah/Hilton Head

jue. 4/10

3:00 pm-7:15 pm

1 stop4h 15m

$249

BuffaloColumbia

BUF - CAE

BUFCAE

Buffalo

jue. 3/20

5:51 pm-11:46 pm

1 stop5h 55m

Columbia Metropolitan

jue. 3/27

5:10 pm-10:46 pm

1 stop5h 36m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 50 results
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Best time to book a flight from Buffalo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Buffalo to South Carolina

Get recent, data-driven insights about flights from Buffalo to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Buffalo to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of $217). Flying from Buffalo to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SC?

Find hourly flight availability from Buffalo to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated febrero 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Buffalo to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated febrero 20, 2025.
Read through reviews of airlines operating flights from Buffalo to South Carolina, such as Southwest, Delta and JetBlue. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Boarding

8.2

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Boarding

8.2

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,220 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Boarding

8.2

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

JetBlue
7.4
Good
3,070 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Boarding

8.2

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,766 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Boarding

8.2

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Boarding

8.2

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to South Carolina?

    Buffalo (BUF) is the airport you will fly out of if you book a flight from Buffalo to South Carolina. It is only a 8.3 mi journey to Buffalo (BUF) from Buffalo’s city center.

  • What are the cheapest airlines to fly from Buffalo to South Carolina one-way?

    The cheapest airlines for a one-way flight from Buffalo to South Carolina are American Airlines ($100), JetBlue ($102), and Delta ($109).

  • What are the most popular routes from Buffalo to South Carolina?

    While some choose either Buffalo - Savannah/Hilton Head or Buffalo - Charleston, Buffalo - Charlotte Douglas is the most popular route from Buffalo to South Carolina.

  • Can I find deals for flights from Buffalo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Buffalo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South Carolina.

  • Can I find deals for business class flights from Buffalo to South Carolina?

    Yes. Cheapflights offers flight deals from Buffalo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of $217). Flying from Buffalo to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Buffalo to South Carolina

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Top 5 airlines flying from Buffalo to South Carolina

Discover the top 5 airlines that operate flights from Buffalo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$175Average$265FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$196Average$395FlexibilityNo cancel feeOn-time71%
DeltaCheapest$198Average$337FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$218Average$400FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$234Average$386FlexibilityNo cancel feeOn-time69%
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