South America

$111+ Cheap flights from the United States to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — BOG
Apr 22 — Apr 291
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1. Tell us where you want to go

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Cheap flight deals from USA to South America

Keep the following information in mind while searching for USA to South America flight deals. Data was last updated April 17, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$278
(Cheapflightsfares)

One-way from

$111
(Mytrip)

Popular in

December

Cheapest in

March

Average price

$753

Good round-trip deal

$222 or less

Good one-way deal

$72 or less
Provider with most accurate pricing for New York (NYC)-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for New York (NYC)-Sao Paulo (SAO) flights.
From USA to South America
One-way flight from USA to South America
Highest demand for flights based on searches. 11% potential increase in price ($108 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($39 potential savings vs. average RT price).
Average for round-trip flights in April 2025
Price to beat on a round-trip flight from USA to South America.
Price to beat on a one-way flight from USA to South America.

Find flight deals from USA to South America

Cheapest flights from USA to South America
Explore the most affordable flight options available from USA to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/310:15 amFLL - MDE
1 stop5h 23mMultiple Airlines
Fri 5/97:55 amMDE - FLL
1 stop8h 15mMultiple Airlines
Deal found 4/17$279
This Cheapflightsfares deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/156:00 amFLL - MDE
1 stop7h 58mSpirit Airlines
Sat 6/72:13 pmMDE - FLL
Nonstop3h 37mSpirit Airlines
Deal found 4/17$285
This Avianca deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/812:30 amJFK - GYE
2 stops12h 55mAvianca
Wed 7/239:45 amGYE - JFK
1 stop11h 55mAvianca
Deal found 4/16$290
This Flysmarter deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/256:50 pmMIA - MDE
Nonstop3h 25mAvianca
Thu 5/111:50 pmMDE - MIA
Nonstop3h 35mAvianca
Deal found 4/16$296
This Flightnetwork deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/266:27 pmMIA - MDE
1 stop5h 25mCopa Airlines
Tue 6/173:29 pmMDE - MIA
1 stop9h 15mCopa Airlines
Deal found 4/15$297
This eDestinos deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/232:09 pmMIA - MDE
1 stop7h 33mArajet
Sun 5/2510:05 amMDE - MIA
1 stop6h 50mArajet
Deal found 4/16$302
This Flightnetwork deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/315:45 pmMIA - MDE
1 stop16h 23mLATAM Airlines
Sat 6/79:43 pmMDE - MIA
1 stop7h 48mLATAM Airlines
Deal found 4/16$305
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/94:30 pmFLL - MDE
Nonstop3h 20mAvianca
Mon 5/1210:20 amMDE - FLL
Nonstop3h 25mAvianca
Deal found 4/17$307
This JetBlue deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/289:58 amFLL - MDE
Nonstop3h 27mJetBlue
Tue 5/61:30 pmMDE - FLL
Nonstop3h 34mJetBlue
Deal found 4/17$308
This Copa Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/126:11 pmFLL - MDE
1 stop15h 07mCopa Airlines
Tue 5/279:15 amMDE - FLL
1 stop5h 59mCopa Airlines
Deal found 4/17$311
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/255:15 pmMIA - MDE
1 stop24h 40mDelta
Sat 5/310:02 amMDE - MIA
1 stop24h 54mDelta
Deal found 4/16$319
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/96:30 amFLL - MDE
1 stop15h 40mUnited Airlines
Wed 6/189:45 amMDE - FLL
1 stop11h 28mUnited Airlines
Deal found 4/17$323

Cheapflights Fare Finder

Customize your flight search to find flights from USA to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from the United States to South America that are best for you.

Fly from

USA

Fly to

South America

Route

Depart

Return

Price

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Mon 4/28

10:50 am-1:15 pm

Nonstop3h 25m

Medellín Jose Maria Cordova Intl

Wed 5/7

1:53 pm-10:57 pm

1 stop8h 04m

$278

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Sat 5/3

10:15 am-2:38 pm

1 stop5h 23m

Medellín Jose Maria Cordova Intl

Fri 5/9

7:55 am-5:10 pm

1 stop8h 15m

$279

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Tue 5/6

3:20 pm-10:26 pm

1 stop8h 06m

Medellín Jose Maria Cordova Intl

Wed 5/7

10:20 am-2:45 pm

Nonstop3h 25m

$285

New YorkGuayaquil

JFK - GYE

JFKGYE

New York John F Kennedy Intl

Tue 7/8

12:30 am-12:25 pm

2 stops12h 55m

Guayaquil Jose Joaquin de Olmedo

Wed 7/23

9:45 am-10:40 pm

1 stop11h 55m

$290

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Fri 4/25

6:50 pm-9:15 pm

Nonstop3h 25m

Medellín Jose Maria Cordova Intl

Thu 5/1

11:50 pm-4:25 am

Nonstop3h 35m

$296

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Mon 5/26

6:27 pm-10:52 pm

1 stop5h 25m

Medellín Jose Maria Cordova Intl

Tue 6/17

3:29 pm-1:44 am

1 stop9h 15m

$297

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Fri 5/23

2:09 pm-8:42 pm

1 stop7h 33m

Medellín Jose Maria Cordova Intl

Sun 5/25

10:05 am-5:55 pm

1 stop6h 50m

$302

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Sat 5/31

5:45 pm-9:08 am

1 stop16h 23m

Medellín Jose Maria Cordova Intl

Sat 6/7

9:43 pm-6:31 am

1 stop7h 48m

$305

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Wed 5/21

6:11 pm-8:18 am

1 stop15h 07m

Medellín Jose Maria Cordova Intl

Tue 5/27

6:39 am-4:14 pm

1 stop8h 35m

$311

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Fri 4/25

5:15 pm-4:55 pm

1 stop24h 40m

Medellín Jose Maria Cordova Intl

Sat 5/3

10:02 am-11:56 am

1 stop24h 54m

$319

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 60 results
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Best time to book a flight from USA to South America

Have a flexible travel schedule? Discover the best time to fly to South America from USA with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the United States to South America

What is the cheapest month to book a flight from USA to South America?

Currently, May is the cheapest month in which you can book a flight from USA to South America (average of $359). Flying from USA to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from US to SA?

Find hourly flight availability from USA to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from USA to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 17, 2025.

Entertainment

6.8

Boarding

8.2

Comfort

7.9

Food

6.8

Crew

8.5

Overall

8.2

Reviews

1 / 9
6.0
Good

Anonymous,Mar 2025

JFK - GEO

Air hostesses were friendly. There should be more options for tea.

Entertainment

6.8

Boarding

8.2

Comfort

7.9

Food

6.8

Crew

8.5

Overall

8.2

Reviews

1 / 9
6.0
Good

Anonymous,Mar 2025

JFK - GEO

Air hostesses were friendly. There should be more options for tea.
8.0
Very good

Entertainment

6.8

Boarding

8.2

Comfort

7.9

Food

6.8

Crew

8.5

Overall

8.2

Reviews

1 / 9
6.0
Good

Anonymous,Mar 2025

JFK - GEO

Air hostesses were friendly. There should be more options for tea.

Entertainment

6.8

Boarding

8.2

Comfort

7.9

Food

6.8

Crew

8.5

Overall

8.2

Reviews

1 / 9
6.0
Good

Anonymous,Mar 2025

JFK - GEO

Air hostesses were friendly. There should be more options for tea.

Entertainment

6.8

Boarding

8.2

Comfort

7.9

Food

6.8

Crew

8.5

Overall

8.2

Reviews

1 / 9
6.0
Good

Anonymous,Mar 2025

JFK - GEO

Air hostesses were friendly. There should be more options for tea.

Entertainment

6.8

Boarding

8.2

Comfort

7.9

Food

6.8

Crew

8.5

Overall

8.2

Reviews

1 / 9
6.0
Good

Anonymous,Mar 2025

JFK - GEO

Air hostesses were friendly. There should be more options for tea.

Related info for your journey

Find useful and relevant information for your journey from USA to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How popular is this USA to South America flight route?

  • What are the cheapest airlines to fly from USA to South America one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $113. However, be on the lookout for offers from Avianca and Arajet, as they are both options that can get you from USA to South America for a low price.

  • Can I find deals for flights from USA to South America that include hotel bookings?

    Yes. In addition to deals on USA to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from USA to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from USA to South America.

  • Can I find deals for business class flights from USA to South America?

    Yes. Cheapflights offers flight deals from USA to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from USA to South America?

    Currently, May is the cheapest month in which you can book a flight from USA to South America (average of $359). Flying from USA to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for USA to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 10 airlines flying from USA to South America

Discover the top 10 airlines that operate flights from USA to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$78Average$98FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$87Average$548FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$127Average$943FlexibilityNo cancel feeOn-time69%
Spirit AirlinesCheapest$128Average$511FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$158Average$868FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$164Average$750FlexibilityNo cancel feeOn-time70%
AviancaCheapest$184Average$659FlexibilityNo cancel feeOn-time71%
DeltaCheapest$207Average$911FlexibilityNo cancel feeOn-timeN/A
VolarisCheapest$242Average$466FlexibilityNo cancel feeOn-time79%
EmiratesCheapest$286Average$338FlexibilityNo cancel feeOn-time75%

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