South America

$86+ Cheap flights from South Carolina to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BOG
Feb 25 — Mar 41
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Cheap flight deals from South Carolina to South America

Keep the following information in mind while searching for South Carolina to South America flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$245
(FlightHub)

One-way from

$86
(FlightHub)
Provider with most accurate pricing for Myrtle Beach Intl-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Sao Paulo (SAO) flights.
From South Carolina to South America
One-way flight from South Carolina to South America

Find flight deals from South Carolina to South America

Cheapest flights from South Carolina to South America
Explore the most affordable flight options available from South Carolina to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This FlightHub deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/247:00 amCLT - CTG
1 stop6h 07mSpirit Airlines
Fri 4/181:12 pmCTG - CLT
1 stop8h 26mSpirit Airlines
Deal found 2/19$245
This Cheapflightsfares deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/267:00 amCLT - BOG
1 stop7h 04mSpirit Airlines
Sat 5/31:59 pmBOG - CLT
1 stop7h 39mSpirit Airlines
Deal found 2/19$263
This Cheapflightsfares deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/176:55 amCLT - MDE
1 stop7h 13mSpirit Airlines
Wed 4/162:14 pmMDE - CLT
1 stop7h 24mSpirit Airlines
Deal found 2/19$331
This Avianca Connect deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1710:30 amCLT - CTG
2 stops13h 29mMultiple Airlines
Tue 4/296:06 amCTG - CLT
2 stops15h 32mMultiple Airlines
Deal found 2/20$333
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/257:00 amCLT - BOG
1 stop7h 04mMultiple Airlines
Sat 4/261:59 pmBOG - CLT
2 stops17h 49mMultiple Airlines
Deal found 2/19$349
This Avianca Connect deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/157:24 pmCLT - MDE
1 stop22h 21mMultiple Airlines
Tue 3/188:20 amMDE - CLT
1 stop28h 02mMultiple Airlines
Deal found 2/19$361
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/186:30 amCLT - MDE
2 stops23h 12mUnited Airlines
Fri 7/49:45 amMDE - CLT
2 stops23h 37mUnited Airlines
Deal found 2/19$419
This Avianca Connect deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1410:30 amCLT - GYE
2 stops13h 10mMultiple Airlines
Mon 4/213:35 amGYE - CLT
2 stops18h 03mMultiple Airlines
Deal found 2/20$449
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/312:49 pmCLT - BOG
1 stop6h 41mLATAM Airlines
Wed 3/269:00 amBOG - CLT
1 stop8h 09mLATAM Airlines
Deal found 2/19$452
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/121:30 pmCLT - BOG
1 stop11h 29mAmerican Airlines
Sun 3/1612:10 amBOG - CLT
1 stop14h 41mAmerican Airlines
Deal found 2/19$453
This United deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/125:26 pmCLT - BOG
2 stops12h 44mUnited Airlines
Tue 3/181:30 amBOG - CLT
2 stops21h 29mUnited Airlines
Deal found 2/19$457
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1411:00 amCLT - CTG
1 stop9h 55mAmerican Airlines
Mon 3/173:15 pmCTG - CLT
1 stop7h 54mAmerican Airlines
Deal found 2/20$466

Find flights from South Carolina to South America within your budget

Customize your flight search to find flights from South Carolina to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

South Carolina

Fly to

South America

Route

Depart

Return

Price

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Mon 3/24

7:00 am-12:07 pm

1 stop6h 07m

Cartagena Rafael Nunez

Fri 4/18

1:12 pm-10:38 pm

1 stop8h 26m

$245

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

Sat 4/26

7:00 am-1:04 pm

1 stop7h 04m

Bogotá El Dorado

Sat 5/3

1:59 pm-10:38 pm

1 stop7h 39m

$263

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Mon 3/17

6:55 am-1:08 pm

1 stop7h 13m

Medellín Jose Maria Cordova Intl

Wed 4/16

2:14 pm-10:38 pm

1 stop7h 24m

$331

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Thu 4/17

10:30 am-10:59 pm

2 stops13h 29m

Cartagena Rafael Nunez

Tue 4/29

6:06 am-10:38 pm

2 stops15h 32m

$333

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

Fri 4/25

7:00 am-1:04 pm

1 stop7h 04m

Bogotá El Dorado

Sat 4/26

1:59 pm-8:48 am

2 stops17h 49m

$349

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sat 3/15

7:24 pm-4:45 pm

1 stop22h 21m

Medellín Jose Maria Cordova Intl

Tue 3/18

8:20 am-1:22 pm

1 stop28h 02m

$361

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sat 5/3

10:21 am-9:10 pm

2 stops11h 49m

Medellín Jose Maria Cordova Intl

Tue 5/6

9:45 am-10:21 am

2 stops23h 36m

$426

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Mon 4/14

10:30 am-10:40 pm

2 stops13h 10m

Guayaquil Jose Joaquin de Olmedo

Mon 4/21

3:35 am-10:38 pm

2 stops18h 03m

$449

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

Mon 3/3

12:49 pm-7:30 pm

1 stop6h 41m

Bogotá El Dorado

Wed 3/26

9:00 am-6:09 pm

1 stop8h 09m

$452

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

Wed 3/12

1:30 pm-11:59 pm

1 stop11h 29m

Bogotá El Dorado

Sun 3/16

12:10 am-3:51 pm

1 stop14h 41m

$453

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to South America

Have a flexible travel schedule? Discover the best time to fly to South America from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to South America

Get recent, data-driven insights about flights from South Carolina to South America including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to South America?

Currently, May is the cheapest month in which you can book a flight from South Carolina to South America (average of $359). Flying from South Carolina to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SA?

Find hourly flight availability from South Carolina to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated February 20, 2025.
8.0
Very good

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

8.0

Comfort

8.0

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

8.0
Very good
8.0
Very good

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

8.0

Comfort

8.0

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

8.0
Very good

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

8.0

Comfort

8.0

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

8.0
Very good

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

8.0

Comfort

8.0

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

8.0
Very good

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

8.0

Comfort

8.0

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

8.0
Very good

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

8.0

Comfort

8.0

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from South Carolina to South America one-way?

    $86 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Copa Airlines and Avianca, with prices starting from $259 and $270, respectively.

  • Can I find deals for flights from South Carolina to South America that include hotel bookings?

    Yes. In addition to deals on South Carolina to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to South America.

  • Can I find deals for business class flights from South Carolina to South America?

    Yes. Cheapflights offers flight deals from South Carolina to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to South America?

    Currently, May is the cheapest month in which you can book a flight from South Carolina to South America (average of $359). Flying from South Carolina to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from South Carolina to South America

Discover the top 4 airlines that operate flights from South Carolina to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$199Average$410FlexibilityNo cancel feeOn-time65%
DeltaCheapest$355Average$887FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$383Average$806FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$502Average$903FlexibilityNo cancel feeOn-time81%
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