What are the cheapest airlines to fly from Santa Ana to South America one-way?

$206 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Copa Airlines and LATAM Airlines, with prices starting from $360 and $373, respectively.

What are the most popular routes from Santa Ana to South America?

The most popular flight routes from Santa Ana to South America are Santa Ana J. Wayne/Orange Cnty - Medellín Jose Maria Cordova Intl, Santa Ana J. Wayne/Orange Cnty - Quito Mariscal Sucr and Santa Ana J. Wayne/Orange Cnty - Bogotá El Dorado.

How far in advance should I book a flight from Santa Ana to South America?

Find a great deal and save up to 101% by booking at least 52 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Santa Ana to South America within the next two weeks, with the cheapest ticket starting at $537.

What is the cheapest month to fly from Santa Ana to South America?

Our data shows that February tends to be the cheapest month to fly to South America from Santa Ana. Users have commonly found prices around $686 for the month, but tickets can be as low as $400. Due to multiple factors, prepare for potentially higher prices in December.

What airport do you fly from for flights from Santa Ana to South America?

Santa Ana J. Wayne/Orange Cnty (SNA) is the airport you will fly out of if you book a flight from Santa Ana to South America. It is only a 4.8 mi journey to J. Wayne/Orange Cnty (SNA) from Santa Ana’s city center.

Can I find deals for flights from Santa Ana to South America that include hotel bookings?

Yes. In addition to deals on Santa Ana to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santa Ana to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to South America.

Can I find deals for business class flights from Santa Ana to South America?

Yes. Cheapflights offers flight deals from Santa Ana to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$690+ Flights from Santa Ana to South America

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Cheap flight deals from Santa Ana to South America

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$414 (CheapOair)
One-way from	$206 (CheapOair)
Popular in	December
Cheapest in	February
Average price	$621

Provider with most accurate pricing for Los Angeles-Sao Paulo (SAO) flight deals.

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Provider most trusted by Cheapflights users for Los Angeles-Sao Paulo (SAO) flights.

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From Santa Ana J. Wayne/Orange Cnty to South America

Search Deals

One-way flight from Santa Ana J. Wayne/Orange Cnty to South America

Search Deals

Highest demand for flights based on searches. 15% potential increase in price ($127 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 6% potential price decrease ($39 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

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Find flight deals from Santa Ana to South America

Cheapest flights from Santa Ana to South America
Explore the most affordable flight options available from Santa Ana to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

Sat 5/104:27 pmSNA - BOG

2 stops18h 38mSpirit Airlines

Fri 5/162:07 pmBOG - SNA

2 stops22h 45mSpirit Airlines

Deal found 4/22

$414

Thu 5/296:45 amSNA - MDE

2 stops28h 30mSpirit Airlines

Mon 6/22:13 pmMDE - SNA

2 stops22h 39mSpirit Airlines

Deal found 4/21

$432

Thu 6/125:22 pmSNA - CTG

2 stops16h 48mSpirit Airlines

Wed 6/181:15 pmCTG - SNA

2 stops24h 35mSpirit Airlines

Deal found 4/22

$497

Thu 6/125:22 pmSNA - CTG

3 stops34h 53mMultiple Airlines

Wed 6/181:15 pmCTG - SNA

2 stops24h 35mMultiple Airlines

Deal found 4/22

$503

Wed 10/88:00 amSNA - BOG

1 stop9h 20mUnited Airlines

Fri 10/2412:14 amBOG - SNA

2 stops22h 29mUnited Airlines

Deal found 4/22

$513

Mon 6/306:50 amSNA - MDE

2 stops19h 52mUnited Airlines

Sun 7/2012:15 amMDE - SNA

2 stops22h 52mUnited Airlines

Deal found 4/22

$537

Fri 6/63:00 pmSNA - CLO

2 stops17h 43mMultiple Airlines

Fri 6/135:41 amCLO - SNA

2 stops18h 19mMultiple Airlines

Deal found 4/22

$557

Mon 6/306:45 amSNA - MDE

2 stops14h 50mAmerican Airlines

Thu 7/246:00 amMDE - SNA

2 stops17h 51mAmerican Airlines

Deal found 4/22

$649

Sun 5/253:14 pmSNA - BOG

2 stops19h 51mAmerican Airlines

Sat 5/3112:25 amBOG - SNA

1 stop12h 16mAmerican Airlines

Deal found 4/22

$655

Fri 6/63:00 pmSNA - CLO

2 stops24h 26mUnited Airlines

Fri 6/134:41 amCLO - SNA

2 stops32h 18mUnited Airlines

Deal found 4/22

$659

Mon 6/303:27 pmSNA - MDE

2 stops32h 38mMultiple Airlines

Thu 7/241:25 pmMDE - SNA

3 stops22h 54mMultiple Airlines

Deal found 4/22

$666

Tue 9/167:00 pmSNA - LIM

2 stops26h 00mUnited Airlines

Thu 9/2512:40 amLIM - SNA

1 stop12h 27mUnited Airlines

Deal found 4/21

$669

Best flights from Santa Ana to South America
Discover carefully curated flight deals from Santa Ana to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 22, 2025.

Sat 5/104:27 pmSNA - BOG

2 stops18h 38mSpirit Airlines

Fri 5/162:07 pmBOG - SNA

2 stops22h 45mSpirit Airlines

Deal found 4/22

$414

Thu 6/125:22 pmSNA - CTG

3 stops34h 53mMultiple Airlines

Wed 6/181:15 pmCTG - SNA

2 stops24h 35mMultiple Airlines

Deal found 4/22

$503

Wed 10/88:00 amSNA - BOG

1 stop9h 20mUnited Airlines

Fri 10/2412:14 amBOG - SNA

2 stops22h 29mUnited Airlines

Deal found 4/22

$513

Mon 6/306:45 amSNA - MDE

2 stops14h 50mAmerican Airlines

Thu 7/246:00 amMDE - SNA

2 stops17h 51mAmerican Airlines

Deal found 4/22

$649

Tue 9/169:20 pmSNA - BOG

1 stop14h 20mLATAM Airlines

Tue 9/239:00 amBOG - SNA

1 stop15h 20mLATAM Airlines

Deal found 4/22

$710

Sun 5/251:05 pmSNA - BOG

2 stops22h 35mDelta

Sat 5/311:35 amBOG - SNA

2 stops22h 40mDelta

Deal found 4/22

$733

Thu 5/296:45 amSNA - MDE

2 stops28h 30mSpirit Airlines

Mon 6/22:13 pmMDE - SNA

2 stops22h 39mSpirit Airlines

Deal found 4/21

$432

Tue 5/271:35 pmSNA - GRU

2 stops39h 40mAir Canada

Wed 6/49:40 pmGRU - SNA

2 stops42h 42mAir Canada

Deal found 4/22

$923

Thu 6/57:13 pmSNA - GRU

2 stops25h 17mCopa Airlines

Wed 6/113:10 amGRU - SNA

2 stops23h 02mCopa Airlines

Deal found 4/22

$998

Mon 6/303:04 pmSNA - MDE

1 stop11h 38mUnited Airlines

Sun 7/2012:15 amMDE - SNA

2 stops22h 52mUnited Airlines

Deal found 4/22

$537

Thu 6/125:22 pmSNA - CTG

2 stops16h 48mSpirit Airlines

Wed 6/181:15 pmCTG - SNA

2 stops24h 35mSpirit Airlines

Deal found 4/22

$497

Fri 6/63:00 pmSNA - CLO

2 stops17h 43mMultiple Airlines

Fri 6/135:41 amCLO - SNA

2 stops18h 19mMultiple Airlines

Deal found 4/22

$557

Last-minute flights from Santa Ana to South America
Discover last-minute flight deals from Santa Ana to South America. Data last updated April 22, 2025 and is based on user searches.

Fri 4/253:36 pmSNA - CLO

2 stops29h 49mUnited Airlines

Fri 5/24:41 amCLO - SNA

2 stops32h 35mUnited Airlines

Deal found 4/22

$895

Sun 4/273:11 pmSNA - MDE

2 stops20h 04mSpirit Airlines

Fri 5/22:14 pmMDE - SNA

2 stops21h 31mSpirit Airlines

Deal found 4/22

$674

Mon 4/288:25 pmSNA - GRU

2 stops47h 45mCopa Airlines

Thu 5/11:40 amGRU - SNA

2 stops24h 20mCopa Airlines

Deal found 4/20

$5,493

Fri 5/28:20 amSNA - BOG

1 stop9h 00mUnited Airlines

Wed 5/78:30 amBOG - SNA

1 stop15h 06mUnited Airlines

Deal found 4/22

$629

Fri 5/21:35 pmSNA - BOG

2 stops36h 30mAir Canada

Wed 5/79:00 amBOG - SNA

2 stops29h 32mAir Canada

Deal found 4/22

$934

Sat 5/104:27 pmSNA - BOG

2 stops18h 38mSpirit Airlines

Fri 5/162:07 pmBOG - SNA

2 stops22h 45mSpirit Airlines

Deal found 4/22

$414

Sun 5/189:20 pmSNA - BOG

1 stop14h 20mLATAM Airlines

Sun 6/19:00 amBOG - SNA

1 stop15h 15mLATAM Airlines

Deal found 4/22

$729

Sun 5/189:20 pmSNA - LIM

1 stop21h 50mLATAM Airlines

Thu 5/2911:20 pmLIM - SNA

1 stop13h 50mLATAM Airlines

Deal found 4/20

$868

Mon 5/197:58 pmSNA - LIM

2 stops31h 08mMultiple Airlines

Mon 5/266:14 amLIM - SNA

2 stops41h 03mMultiple Airlines

Deal found 4/22

$746

Mon 5/199:20 pmSNA - LIM

1 stop21h 50mDelta

Mon 5/2611:20 pmLIM - SNA

1 stop13h 47mDelta

Deal found 4/22

$934

Sun 5/253:14 pmSNA - BOG

2 stops19h 51mAmerican Airlines

Sat 5/3112:25 amBOG - SNA

1 stop12h 16mAmerican Airlines

Deal found 4/22

$655

Sun 5/251:05 pmSNA - BOG

2 stops22h 35mDelta

Sat 5/311:35 amBOG - SNA

2 stops22h 40mDelta

Deal found 4/22

$733

One-way flights from Santa Ana to South America
Search for one-way flight options from Santa Ana to South America. Find affordable one-way fares based on user searches. Data last updated April 22, 2025.

Thu 5/226:45 amSNA - BOG

2 stops28h 20mSpirit Airlines

Deal found 4/22

$206

Fri 5/167:58 pmSNA - MDE

2 stops15h 00mSpirit Airlines

Deal found 4/20

$238

Wed 5/287:15 pmSNA - BOG

2 stops16h 14mCopa Airlines

Deal found 4/22

$360

Sat 5/242:15 pmSNA - BOG

1 stop21h 25mLATAM Airlines

Deal found 4/22

$373

Wed 4/3010:56 amSNA - UIO

2 stops13h 49mMultiple Airlines

Deal found 4/22

$392

Wed 4/3010:20 amSNA - UIO

1 stop11h 05mUnited Airlines

Deal found 4/22

$400

Tue 7/153:04 pmSNA - LIM

1 stop29h 56mUnited Airlines

Deal found 4/20

$438

Wed 5/148:25 pmSNA - MDE

2 stops22h 45mUnited Airlines

Deal found 4/20

$457

Fri 7/182:29 pmSNA - CTG

1 stop20h 23mLATAM Airlines

Deal found 4/22

$494

Mon 7/219:20 pmSNA - LIM

1 stop21h 50mLATAM Airlines

Deal found 4/22

$512

Wed 7/96:45 amSNA - UIO

1 stop11h 15mLATAM Airlines

Deal found 4/22

$549

Sun 5/48:20 amSNA - GRU

1 stop19h 15mUnited Airlines

Deal found 4/20

$558

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaBogotá

SNA - BOG

SNABOG

Santa Ana J. Wayne/Orange Cnty

Sat 5/10

4:27 pm-1:05 pm

2 stops18h 38m

Bogotá El Dorado

Fri 5/16

2:07 pm-10:52 am

2 stops22h 45m

$414

Santa AnaMedellín

SNA - MDE

SNAMDE

Santa Ana J. Wayne/Orange Cnty

Thu 5/29

6:45 am-1:15 pm

2 stops28h 30m

Medellín Jose Maria Cordova Intl

Mon 6/2

2:13 pm-10:52 am

2 stops22h 39m

$432

Santa AnaCartagena

SNA - CTG

SNACTG

Santa Ana J. Wayne/Orange Cnty

Thu 6/12

5:22 pm-12:10 pm

2 stops16h 48m

Cartagena Rafael Nunez

Wed 6/18

1:15 pm-11:50 am

2 stops24h 35m

$497

Santa AnaCartagena

SNA - CTG

SNACTG

Santa Ana J. Wayne/Orange Cnty

Thu 6/12

5:22 pm-6:15 am

3 stops34h 53m

Cartagena Rafael Nunez

Wed 6/18

1:15 pm-11:50 am

2 stops24h 35m

$503

Santa AnaBogotá

SNA - BOG

SNABOG

Santa Ana J. Wayne/Orange Cnty

Wed 10/8

8:00 am-7:20 pm

1 stop9h 20m

Bogotá El Dorado

Fri 10/24

12:14 am-8:43 pm

2 stops22h 29m

$513

Santa AnaMedellín

SNA - MDE

SNAMDE

Santa Ana J. Wayne/Orange Cnty

Mon 6/30

3:04 pm-4:42 am

1 stop11h 38m

Medellín Jose Maria Cordova Intl

Sun 7/20

12:15 am-9:07 pm

2 stops22h 52m

$537

Santa AnaCali

SNA - CLO

SNACLO

Santa Ana J. Wayne/Orange Cnty

Fri 6/6

3:00 pm-10:43 am

2 stops17h 43m

Cali Alfonso B. Aragon Intl

Fri 6/13

5:41 am-10:00 pm

2 stops18h 19m

$557

Santa AnaMedellín

SNA - MDE

SNAMDE

Santa Ana J. Wayne/Orange Cnty

Mon 6/30

6:45 am-11:35 pm

2 stops14h 50m

Medellín Jose Maria Cordova Intl

Thu 7/24

6:00 am-9:51 pm

2 stops17h 51m

$649

Santa AnaBogotá

SNA - BOG

SNABOG

Santa Ana J. Wayne/Orange Cnty

Sun 5/25

3:14 pm-1:05 pm

2 stops19h 51m

Bogotá El Dorado

Sat 5/31

12:25 am-10:41 am

1 stop12h 16m

$655

Santa AnaCali

SNA - CLO

SNACLO

Santa Ana J. Wayne/Orange Cnty

Fri 6/6

3:00 pm-5:26 pm

2 stops24h 26m

Cali Alfonso B. Aragon Intl

Fri 6/13

4:41 am-10:59 am

2 stops32h 18m

$659

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Showing 1-10 of 47 results

...

Best time to book a flight from Santa Ana to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Santa Ana with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to South America

What is the cheapest month to book a flight from Santa Ana to South America?

Currently, May is the cheapest month in which you can book a flight from Santa Ana to South America (average of $359). Flying from Santa Ana to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SNA to SA?

When flying from Santa Ana to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,920 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines

7.5

Good

1,764 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines

7.5

Good

1,408 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

8,683 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What airport do you fly from for flights from Santa Ana to South America?
Santa Ana J. Wayne/Orange Cnty (SNA) is the airport you will fly out of if you book a flight from Santa Ana to South America. It is only a 4.8 mi journey to J. Wayne/Orange Cnty (SNA) from Santa Ana’s city center.
What are the cheapest airlines to fly from Santa Ana to South America one-way?
$206 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Copa Airlines and LATAM Airlines, with prices starting from $360 and $373, respectively.
What are the most popular routes from Santa Ana to South America?
The most popular flight routes from Santa Ana to South America are Santa Ana J. Wayne/Orange Cnty - Medellín Jose Maria Cordova Intl, Santa Ana J. Wayne/Orange Cnty - Quito Mariscal Sucr and Santa Ana J. Wayne/Orange Cnty - Bogotá El Dorado.
Can I find deals for flights from Santa Ana to South America that include hotel bookings?
Yes. In addition to deals on Santa Ana to South America flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santa Ana to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to South America.
Can I find deals for business class flights from Santa Ana to South America?
Yes. Cheapflights offers flight deals from Santa Ana to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santa Ana to South America?
Currently, May is the cheapest month in which you can book a flight from Santa Ana to South America (average of $359). Flying from Santa Ana to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Santa Ana to South America flights

Top 4 airlines flying from Santa Ana to South America

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$413	Average$956	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$499	Average$1,075	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$742	Average$901	FlexibilityNo cancel fee	On-timeN/A
LATAM Airlines	Cheapest$788	Average$905	FlexibilityNo cancel fee	On-time81%

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$206+ Cheap flights from Santa Ana (SNA) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santa Ana to South America with Cheapflights

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Cheap flight deals from Santa Ana to South America

Keep the following information in mind while searching for Santa Ana to South America flight deals. Data was last updated April 22, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Santa Ana to South America

Cheapest flights from Santa Ana to South AmericaExplore the most affordable flight options available from Santa Ana to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

Explore the most affordable flight options available from Santa Ana to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to South America that are best for you.

Best time to book a flight from Santa Ana to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Santa Ana with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to South America

What is the cheapest month to book a flight from Santa Ana to South America?

What is the cheapest time of day to fly from SNA to SA?

Find hourly flight availability from Santa Ana to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

Reviews of airlines servicing South America

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Santa Ana to South America?

What are the cheapest airlines to fly from Santa Ana to South America one-way?

What are the most popular routes from Santa Ana to South America?

Can I find deals for flights from Santa Ana to South America that include hotel bookings?

How can I find direct flights from Santa Ana to South America?

Can I find deals for business class flights from Santa Ana to South America?

What is the cheapest month to book a flight from Santa Ana to South America?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santa Ana to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Santa Ana to South America

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Cheapest flights from Santa Ana to South America
Explore the most affordable flight options available from Santa Ana to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.