South America

$183+ Cheap flights from San Francisco (SFO) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — BOG
Apr 8 — Apr 151
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Cheap flight deals from San Francisco to South America

Keep the following information in mind while searching for San Francisco to South America flight deals. Data was last updated April 3, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$445
(Avianca)

One-way from

$183
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$698
Provider with most accurate pricing for San Francisco-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for San Francisco-Sao Paulo (SAO) flights.
From San Francisco to South America
One-way flight from San Francisco to South America
Highest demand for flights based on searches. 12% potential increase in price ($106 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($36 potential savings vs. average RT price).
Average for round-trip flights in April 2025

Find flight deals from San Francisco to South America

Cheapest flights from San Francisco to South America
Explore the most affordable flight options available from San Francisco to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2025.

This Avianca deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/292:20 pmSFO - BOG
1 stop9h 35mAvianca
Tue 4/293:59 amBOG - SFO
1 stop10h 36mAvianca
Deal found 4/2$445
This Booking.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/61:40 amSFO - BOG
1 stop9h 49mCopa Airlines
Mon 4/216:17 pmBOG - SFO
1 stop26h 13mCopa Airlines
Deal found 4/2$458
This FlightHub deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/202:20 pmSFO - MDE
1 stop9h 45mAvianca
Thu 10/23:15 amMDE - SFO
1 stop11h 20mAvianca
Deal found 4/3$459
This Copa Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/91:37 amSFO - MDE
1 stop13h 24mCopa Airlines
Sun 5/1811:29 amMDE - SFO
1 stop14h 11mCopa Airlines
Deal found 4/3$474
This Avianca deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/12:30 amSFO - CTG
2 stops13h 09mAvianca
Tue 5/611:33 amCTG - SFO
2 stops13h 12mAvianca
Deal found 4/2$476
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/912:32 amSFO - BOG
1 stop25h 38mUnited Airlines
Wed 11/261:30 amBOG - SFO
1 stop25h 25mUnited Airlines
Deal found 4/2$496
This United deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/277:30 amSFO - MDE
1 stop11h 40mUnited Airlines
Tue 6/249:45 amMDE - SFO
1 stop16h 14mUnited Airlines
Deal found 4/2$503
This KAYAK deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/21:37 amSFO - LIM
1 stop21h 48mCopa Airlines
Thu 5/292:35 amLIM - SFO
1 stop23h 05mCopa Airlines
Deal found 4/2$507
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1212:47 amSFO - MDE
2 stops17h 28mAmerican Airlines
Fri 4/186:00 amMDE - SFO
1 stop16h 36mAmerican Airlines
Deal found 4/3$507
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/57:10 amSFO - BOG
1 stop10h 05mDelta
Sat 5/102:55 pmBOG - SFO
2 stops21h 32mDelta
Deal found 4/2$507
This Gotogate deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/32:20 pmSFO - LIM
1 stop11h 05mAvianca
Thu 5/291:40 amLIM - SFO
1 stop12h 55mAvianca
Deal found 4/2$515
This United deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2710:55 amSFO - CTG
1 stop19h 48mUnited Airlines
Mon 6/29:38 amCTG - SFO
1 stop13h 20mUnited Airlines
Deal found 4/2$520

Cheapflights Fare Finder

Customize your flight search to find flights from San Francisco to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2025.
Use the filters below to find and compare flights from San Francisco to South America that are best for you.

Fly from

San Francisco

Fly to

South America

Route

Depart

Return

Price

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Tue 4/29

2:20 pm-1:55 am

1 stop9h 35m

Bogotá El Dorado

Tue 4/29

3:59 am-12:35 pm

1 stop10h 36m

$445

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Sun 4/6

1:40 am-1:29 pm

1 stop9h 49m

Bogotá El Dorado

Mon 4/21

6:17 pm-6:30 pm

1 stop26h 13m

$458

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Sat 9/20

2:20 pm-2:05 am

1 stop9h 45m

Medellín Jose Maria Cordova Intl

Thu 10/2

3:15 am-12:35 pm

1 stop11h 20m

$459

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Fri 5/9

1:37 am-5:01 pm

1 stop13h 24m

Medellín Jose Maria Cordova Intl

Sun 5/18

11:29 am-11:40 pm

1 stop14h 11m

$474

San FranciscoCartagena

SFO - CTG

SFOCTG

San Francisco

Thu 5/1

12:05 am-4:33 pm

2 stops14h 28m

Cartagena Rafael Nunez

Tue 5/6

10:45 am-11:55 pm

3 stops15h 10m

$476

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Tue 5/27

7:30 am-9:10 pm

1 stop11h 40m

Medellín Jose Maria Cordova Intl

Tue 6/24

9:45 am-11:59 pm

1 stop16h 14m

$503

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Wed 6/4

11:59 pm-7:20 pm

1 stop17h 21m

Bogotá El Dorado

Thu 6/12

12:14 am-7:18 pm

1 stop21h 04m

$503

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Sun 4/13

11:59 pm-8:15 pm

2 stops18h 16m

Medellín Jose Maria Cordova Intl

Fri 4/18

6:00 am-9:05 pm

2 stops17h 05m

$507

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Mon 5/5

7:10 am-7:15 pm

1 stop10h 05m

Bogotá El Dorado

Sat 5/10

2:55 pm-10:27 am

2 stops21h 32m

$507

San FranciscoLima

SFO - LIM

SFOLIM

San Francisco

Fri 5/2

1:37 am-1:25 am

1 stop21h 48m

Lima J Chavez Intl

Thu 5/29

2:35 am-11:40 pm

1 stop23h 05m

$507

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/2

Showing 1-10 of 60 results
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Best time to book a flight from San Francisco to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to South America

What is the cheapest month to book a flight from San Francisco to South America?

Currently, May is the cheapest month in which you can book a flight from San Francisco to South America (average of $359). Flying from San Francisco to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to SA?

Find hourly flight availability from San Francisco to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 3, 2025.

When flying from San Francisco to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 3, 2025.
8.0
Very good

Overall

8.0

Boarding

8.1

Food

7.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
8.0
Very good
8.0
Very good

Overall

8.0

Boarding

8.1

Food

7.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
8.0
Very good
8.0
Very good

Overall

8.0

Boarding

8.1

Food

7.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
8.0
Very good

Overall

8.0

Boarding

8.1

Food

7.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
8.0
Very good

Overall

8.0

Boarding

8.1

Food

7.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
8.0
Very good

Overall

8.0

Boarding

8.1

Food

7.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Francisco to South America?

    Most people fly from San Francisco (SFO) if they book a flight from San Francisco to South America. San Francisco is conveniently located just 11.8 mi from San Francisco’s city center.

  • What are the cheapest airlines to fly from San Francisco to South America one-way?

    $200 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on Copa Airlines and United Airlines, with prices starting from $225 and $228, respectively.

  • What are the most popular routes from San Francisco to South America?

  • Can I find deals for flights from San Francisco to South America that include hotel bookings?

    Yes. In addition to deals on San Francisco to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to South America.

  • Can I find deals for business class flights from San Francisco to South America?

    Yes. Cheapflights offers flight deals from San Francisco to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to South America?

    Currently, May is the cheapest month in which you can book a flight from San Francisco to South America (average of $359). Flying from San Francisco to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Francisco to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 10 airlines flying from San Francisco to South America

Discover the top 10 airlines that operate flights from San Francisco to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
VolarisCheapest$242Average$466FlexibilityNo cancel feeOn-time79%
AviancaCheapest$324Average$843FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$343Average$850FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$375Average$782FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$387Average$904FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$389Average$640FlexibilityNo cancel feeOn-time62%
DeltaCheapest$389Average$926FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$389Average$903FlexibilityNo cancel feeOn-time81%
Air CanadaCheapest$579Average$889FlexibilityNo cancel feeOn-time67%
AeroMexico ConnectCheapest$615Average$1,107FlexibilityNo cancel feeOn-timeN/A

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