$175+ Cheap flights from San Francisco (SFO) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — BOG
Apr 27 — May 41
1 adult, Economy
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Find cheap flights from San Francisco to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to South America
Keep the following information in mind while searching for San Francisco to South America flight deals. Data was last updated April 22, 2025.
Most accurate provider | AranGrant 3 stars |
|---|---|
Most trusted provider | AranGrant 3 stars |
Round-trip from | $443 (Priceline) |
One-way from | $175 (Kiwi.com) |
Popular in | December |
Cheapest in | October |
Average price | $718 |
Find flight deals from San Francisco to South America
Cheapest flights from San Francisco to South AmericaExplore the most affordable flight options available from San Francisco to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.
Explore the most affordable flight options available from San Francisco to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.
This Priceline deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1412:05 amSFO - BOG
1 stop12h 04mAvianca
Sat 5/173:59 amBOG - SFO
1 stop10h 36mAvianca
Deal found 4/21![Avianca logo]()
$443
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1212:43 amSFO - BOG
1 stop16h 37mUnited Airlines
Thu 5/2212:14 amBOG - SFO
1 stop25h 20mUnited Airlines
Deal found 4/21![United Airlines logo]()
$446
This FlightHub deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/32:20 pmSFO - MDE
1 stop9h 45mAvianca
Wed 10/83:15 amMDE - SFO
1 stop11h 20mAvianca
Deal found 4/22![Avianca logo]()
$459
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/136:15 amSFO - BOG
1 stop11h 00mDelta
Fri 5/237:00 amBOG - SFO
2 stops19h 21mDelta
Deal found 4/22![Delta logo]()
$459
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/86:51 pmSFO - MDE
1 stop24h 19mUnited Airlines
Tue 5/209:45 amMDE - SFO
1 stop11h 46mUnited Airlines
Deal found 4/22![United Airlines logo]()
$467
This Copa Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/27:52 pmSFO - MDE
1 stop10h 53mCopa Airlines
Sat 5/106:39 amMDE - SFO
1 stop19h 01mCopa Airlines
Deal found 4/22![Copa Airlines logo]()
$474
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/59:00 pmSFO - UIO
2 stops21h 00mDelta
Fri 5/911:20 pmUIO - SFO
2 stops21h 40mDelta
Deal found 4/22![Delta logo]()
$498
This Cheapflightsfares deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/412:05 amSFO - UIO
2 stops20h 20mAvianca
Fri 5/99:43 pmUIO - SFO
2 stops16h 52mAvianca
Deal found 4/22![Avianca logo]()
$500
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2411:37 pmSFO - BOG
1 stop11h 28mAmerican Airlines
Sun 4/2712:25 amBOG - SFO
1 stop20h 39mAmerican Airlines
Deal found 4/21![American Airlines logo]()
$503
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1012:43 amSFO - UIO
1 stop20h 42mUnited Airlines
Fri 5/2312:35 amUIO - SFO
1 stop25h 24mUnited Airlines
Deal found 4/22![United Airlines logo]()
$505
This Gotogate deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/262:20 pmSFO - LIM
2 stops17h 10mAvianca
Fri 10/32:50 amLIM - SFO
2 stops23h 05mAvianca
Deal found 4/22![Avianca logo]()
$506
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/25:02 amSFO - MDE
2 stops13h 13mAmerican Airlines
Sat 5/106:00 amMDE - SFO
2 stops15h 16mAmerican Airlines
Deal found 4/22![American Airlines logo]()
$507
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
Use the filters below to find and compare flights from San Francisco to South America that are best for you.
Fly from
San Francisco
Fly to
South America
Route
Depart
Return
Price
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Wed 5/14
12:05 am-1:20 pm
1 stop11h 15m
Bogotá El Dorado
Mon 5/19
2:20 pm-10:45 pm
1 stop10h 25m
$443
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Mon 5/12
12:43 am-7:20 pm
1 stop16h 37m
Bogotá El Dorado
Thu 5/22
12:14 am-11:34 pm
1 stop25h 20m
$446
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Tue 5/13
11:59 pm-7:58 pm
2 stops17h 59m
Bogotá El Dorado
Fri 5/23
10:45 am-12:21 am
2 stops15h 36m
$459
San FranciscoMedellín
SFO - MDE
SFOMDE
San Francisco
Fri 6/13
2:20 pm-2:05 am
1 stop9h 45m
Medellín Jose Maria Cordova Intl
Wed 6/18
1:25 pm-10:45 pm
2 stops11h 20m
$459
San FranciscoMedellín
SFO - MDE
SFOMDE
San Francisco
Thu 5/8
6:51 pm-9:10 pm
1 stop24h 19m
Medellín Jose Maria Cordova Intl
Tue 5/20
9:45 am-7:31 pm
1 stop11h 46m
$467
San FranciscoMedellín
SFO - MDE
SFOMDE
San Francisco
Fri 5/2
7:52 pm-8:45 am
1 stop10h 53m
Medellín Jose Maria Cordova Intl
Sat 5/10
6:39 am-11:40 pm
1 stop19h 01m
$474
San FranciscoQuito
SFO - UIO
SFOUIO
San Francisco
Mon 5/5
4:00 pm-8:00 pm
2 stops26h 00m
Quito Mariscal Sucr
Wed 5/21
9:11 am-12:21 am
2 stops17h 10m
$498
San FranciscoQuito
SFO - UIO
SFOUIO
San Francisco
Sun 5/4
12:05 am-10:25 pm
2 stops20h 20m
Quito Mariscal Sucr
Fri 5/9
9:43 pm-12:35 pm
2 stops16h 52m
$500
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Fri 4/25
12:47 am-10:30 pm
1 stop19h 43m
Bogotá El Dorado
Mon 4/28
6:30 am-10:54 pm
1 stop18h 24m
$503
San FranciscoQuito
SFO - UIO
SFOUIO
San Francisco
Sat 5/10
12:43 am-11:25 pm
1 stop20h 42m
Quito Mariscal Sucr
Fri 5/23
12:35 am-11:59 pm
1 stop25h 24m
$505
Showing 1-10 of 60 results
Best time to book a flight from San Francisco to South America
Have a flexible travel schedule? Discover the best time to fly to South America from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to South America
What is the cheapest month to book a flight from San Francisco to South America?
Currently, May is the cheapest month in which you can book a flight from San Francisco to South America (average of $359). Flying from San Francisco to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SFO to SA?
Find hourly flight availability from San Francisco to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.
When flying from San Francisco to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Rainfall in South America by month
Plan your trip to South America by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.
Temperature in South America by month
Plan your trip to South America by taking into account the average temperature totals by month.
If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 22, 2025.
Entertainment
7.5
Food
7.1
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 14
2.0
MediocreMike,Feb 2025
NVT - LIS
Entertainment
7.5
Food
7.1
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 14
2.0
MediocreMike,Feb 2025
NVT - LIS
Entertainment
7.5
Food
7.1
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 14
2.0
MediocreMike,Feb 2025
NVT - LIS
Entertainment
7.5
Food
7.1
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 14
2.0
MediocreMike,Feb 2025
NVT - LIS
Entertainment
7.5
Food
7.1
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 14
2.0
MediocreMike,Feb 2025
NVT - LIS
Entertainment
7.5
Food
7.1
Boarding
8.1
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 14
2.0
MediocreMike,Feb 2025
NVT - LIS
Related info for your journey
Find useful and relevant information for your journey from San Francisco to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for San Francisco to South America
See prices for flight routes from nearby airports that may be better suited for you.
Top 10 airlines flying from San Francisco to South America
Discover the top 10 airlines that operate flights from San Francisco to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$242 | Average$466 | FlexibilityNo cancel fee | On-time79% | |
| Cheapest$333 | Average$877 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$354 | Average$892 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$376 | Average$793 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$387 | Average$930 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$389 | Average$637 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$389 | Average$929 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$389 | Average$877 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$579 | Average$878 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$665 | Average$926 | FlexibilityNo cancel fee | On-timeN/A |