South America

$188+ Cheap flights from San Francisco (SFO) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/10. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — BOG
feb. 4 — feb. 111
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Cheap flight deals from San Francisco to South America

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to South America (0SA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated enero 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$439
(Avianca)

One-way from

$188
(Cheapflightsfares)

Popular in

December

Cheapest in

August

Average price

$791
Provider with most accurate pricing for San Francisco-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for San Francisco-Sao Paulo (SAO) flights.
From San Francisco to South America
One-way flight from San Francisco to South America
Highest demand for flights based on searches. 12% potential increase in price ($112 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($37 potential savings vs. average RT price).
Average for round-trip flights in January 2025

Find flight deals from San Francisco to South America

Cheapest flights from San Francisco to South America
Explore the most affordable flight options available from San Francisco to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 30, 2025.

This Avianca deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/191:20 pmSFO - MDE
1 stop9h 35mAvianca
mié. 2/263:20 amMDE - SFO
1 stop11h 40mAvianca
Deal found 1/30$439
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 3/17:20 amSFO - MDE
1 stop11h 45mUnited Airlines
jue. 3/610:45 amMDE - SFO
1 stop15h 50mUnited Airlines
Deal found 1/29$451
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/1711:55 pmSFO - CTG
1 stop11h 16mDelta
jue. 3/272:26 pmCTG - SFO
1 stop11h 56mDelta
Deal found 1/30$456
This Copa Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/171:51 amSFO - CTG
1 stop10h 13mCopa Airlines
mar. 3/259:35 amCTG - SFO
1 stop16h 05mCopa Airlines
Deal found 1/30$458
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/286:40 pmSFO - CTG
2 stops34h 50mUnited Airlines
mié. 3/55:55 pmCTG - SFO
2 stops32h 40mUnited Airlines
Deal found 1/28$459
This Copa Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 1/307:13 pmSFO - MDE
1 stop12h 20mCopa Airlines
jue. 2/69:22 amMDE - SFO
1 stop17h 02mCopa Airlines
Deal found 1/30$473
This United deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/135:00 amSFO - BOG
1 stop14h 35mUnited Airlines
jue. 2/208:15 amBOG - SFO
1 stop19h 15mUnited Airlines
Deal found 1/30$476
This FlightHub deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/611:15 pmSFO - BOG
1 stop12h 10mAvianca
dom. 3/911:00 amBOG - SFO
3 stops13h 55mAvianca
Deal found 1/29$477
This LATAM Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/229:30 pmSFO - CTG
1 stop13h 45mLATAM Airlines
jue. 2/273:30 pmCTG - SFO
1 stop11h 16mLATAM Airlines
Deal found 1/30$481
This KAYAK deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/712:44 amSFO - BOG
1 stop20h 18mCopa Airlines
mar. 2/1811:39 amBOG - SFO
1 stop14h 45mCopa Airlines
Deal found 1/30$484
This Cheapflightsfares deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 3/21:20 pmSFO - LIM
1 stop11h 10mAvianca
mar. 3/111:50 amLIM - SFO
1 stop13h 10mAvianca
Deal found 1/29$487
This Ovago deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/36:00 amSFO - BOG
1 stop10h 30mLATAM Airlines
lun. 2/103:50 pmBOG - SFO
1 stop21h 45mLATAM Airlines
Deal found 1/30$493

Find flights from San Francisco to South America within your budget

Customize your flight search to find flights from San Francisco to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 30, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

mié. 2/19

1:20 pm-1:55 am

1 stop9h 35m

Medellín Jose Maria Cordova Intl

mié. 2/26

3:20 am-12:00 pm

1 stop11h 40m

$439

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

sáb. 3/1

7:20 am-10:05 pm

1 stop11h 45m

Medellín Jose Maria Cordova Intl

jue. 3/6

10:45 am-11:35 pm

1 stop15h 50m

$451

San FranciscoCartagena

SFO - CTG

SFOCTG

San Francisco

lun. 3/17

11:55 pm-1:11 pm

1 stop11h 16m

Cartagena Rafael Nunez

jue. 3/27

2:26 pm-12:22 am

1 stop11h 56m

$456

San FranciscoCartagena

SFO - CTG

SFOCTG

San Francisco

lun. 3/17

1:51 am-2:04 pm

1 stop10h 13m

Cartagena Rafael Nunez

mar. 3/25

9:35 am-11:40 pm

1 stop16h 05m

$458

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

mar. 3/11

1:51 am-7:57 pm

1 stop16h 06m

Medellín Jose Maria Cordova Intl

mié. 3/19

5:05 am-11:40 pm

1 stop20h 35m

$473

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

jue. 2/13

5:00 am-10:35 pm

1 stop14h 35m

Bogotá El Dorado

jue. 2/20

8:15 am-12:30 am

1 stop19h 15m

$476

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

jue. 3/6

11:15 pm-2:25 pm

1 stop12h 10m

Bogotá El Dorado

dom. 3/9

10:11 am-10:55 pm

3 stops14h 44m

$477

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

vie. 3/7

12:51 am-5:12 pm

1 stop13h 21m

Bogotá El Dorado

vie. 4/25

4:59 am-6:30 pm

1 stop15h 31m

$479

San FranciscoCartagena

SFO - CTG

SFOCTG

San Francisco

sáb. 2/22

9:30 pm-2:15 pm

1 stop13h 45m

Cartagena Rafael Nunez

jue. 2/27

3:30 pm-11:46 pm

1 stop11h 16m

$481

San FranciscoLima

SFO - LIM

SFOLIM

San Francisco

dom. 3/2

1:20 pm-3:30 am

1 stop11h 10m

Lima J Chavez Intl

mar. 3/11

1:50 am-1:00 pm

1 stop13h 10m

$487

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/29

Showing 1-10 of 60 results
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Best time to book a flight from San Francisco to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from San Francisco to South America

Get recent, data-driven insights about flights from San Francisco to South America including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from San Francisco to South America?

Currently, May is the cheapest month in which you can book a flight from San Francisco to South America (average of $359). Flying from San Francisco to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to SA?

Find hourly flight availability from San Francisco to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated enero 30, 2025.

When flying from San Francisco to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated enero 30, 2025.

Crew

8.7

Food

7.7

Entertainment

7.8

Boarding

8.4

Comfort

8.2

Overall

8.3

Reviews

1 / 20

10.0
Excellent

L,Nov 2024

SNA - SEA

Excellent crew, great food and decent audio selection. Seats are wide and have plenty of leg room but could use some more padding.

Crew

8.7

Food

7.7

Entertainment

7.8

Boarding

8.4

Comfort

8.2

Overall

8.3

Reviews

1 / 20

10.0
Excellent

L,Nov 2024

SNA - SEA

Excellent crew, great food and decent audio selection. Seats are wide and have plenty of leg room but could use some more padding.

8.0
Very good

Crew

8.7

Food

7.7

Entertainment

7.8

Boarding

8.4

Comfort

8.2

Overall

8.3

Reviews

1 / 20

10.0
Excellent

L,Nov 2024

SNA - SEA

Excellent crew, great food and decent audio selection. Seats are wide and have plenty of leg room but could use some more padding.

8.0
Very good

Crew

8.7

Food

7.7

Entertainment

7.8

Boarding

8.4

Comfort

8.2

Overall

8.3

Reviews

1 / 20

10.0
Excellent

L,Nov 2024

SNA - SEA

Excellent crew, great food and decent audio selection. Seats are wide and have plenty of leg room but could use some more padding.

Crew

8.7

Food

7.7

Entertainment

7.8

Boarding

8.4

Comfort

8.2

Overall

8.3

Reviews

1 / 20

10.0
Excellent

L,Nov 2024

SNA - SEA

Excellent crew, great food and decent audio selection. Seats are wide and have plenty of leg room but could use some more padding.

Crew

8.7

Food

7.7

Entertainment

7.8

Boarding

8.4

Comfort

8.2

Overall

8.3

Reviews

1 / 20

10.0
Excellent

L,Nov 2024

SNA - SEA

Excellent crew, great food and decent audio selection. Seats are wide and have plenty of leg room but could use some more padding.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Francisco to South America?

    Most people fly from San Francisco (SFO) if they book a flight from San Francisco to South America. San Francisco is conveniently located just 11.8 mi from San Francisco’s city center.

  • What are the cheapest airlines to fly from San Francisco to South America one-way?

    $188 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on Copa Airlines and Delta, with prices starting from $199 and $203, respectively.

  • What are the most popular routes from San Francisco to South America?

  • Can I find deals for flights from San Francisco to South America that include hotel bookings?

    Yes. In addition to deals on San Francisco to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to South America.

  • Can I find deals for business class flights from San Francisco to South America?

    Yes. Cheapflights offers flight deals from San Francisco to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to South America?

    Currently, May is the cheapest month in which you can book a flight from San Francisco to South America (average of $359). Flying from San Francisco to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Francisco to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 10 airlines flying from San Francisco to South America

Discover the top 10 airlines that operate flights from San Francisco to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$226Average$868FlexibilityNo cancel feeOn-time69%
VolarisCheapest$242Average$469FlexibilityNo cancel feeOn-time79%
AviancaCheapest$323Average$735FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$339Average$524FlexibilityNo cancel feeOn-time62%
Copa AirlinesCheapest$350Average$773FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$365Average$910FlexibilityNo cancel feeOn-time71%
DeltaCheapest$389Average$909FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$389Average$909FlexibilityNo cancel feeOn-time81%
AeromexicoCheapest$583Average$911FlexibilityNo cancel feeOn-timeN/A
AeroMexico ConnectCheapest$615Average$1,107FlexibilityNo cancel feeOn-timeN/A
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