South America

$184+ Cheap flights from San Diego (SAN) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/21. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — BOG
Apr 20 — Apr 271
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Cheap flight deals from San Diego to South America

Keep the following information in mind while searching for San Diego to South America flight deals. Data was last updated April 15, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$403
(Copa Airlines)

One-way from

$184
(Kiwi.com)

Popular in

December

Cheapest in

February

Average price

$884
Provider with most accurate pricing for San Diego-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for San Diego-Sao Paulo (SAO) flights.
From San Diego to South America
One-way flight from San Diego to South America
Highest demand for flights based on searches. 9% potential increase in price ($106 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($21 potential savings vs. average RT price).
Average for round-trip flights in April 2025

Find flight deals from San Diego to South America

Cheapest flights from San Diego to South America
Explore the most affordable flight options available from San Diego to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.

This Copa Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/208:58 pmSAN - MDE
1 stop15h 17mCopa Airlines
Sun 7/279:15 amMDE - SAN
1 stop10h 29mCopa Airlines
Deal found 4/15$403
This Copa Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/28:58 pmSAN - BOG
1 stop11h 12mCopa Airlines
Mon 7/78:35 amBOG - SAN
1 stop11h 09mCopa Airlines
Deal found 4/14$403
This Copa Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/249:03 pmSAN - CTG
1 stop9h 19mCopa Airlines
Mon 9/296:20 amCTG - SAN
1 stop13h 30mCopa Airlines
Deal found 4/15$408
This FlightHub deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/116:58 pmSAN - MDE
2 stops16h 17mSpirit Airlines
Sat 5/242:13 pmMDE - SAN
2 stops19h 00mSpirit Airlines
Deal found 4/15$417
This Expedia deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/156:58 pmSAN - BOG
2 stops16h 07mSpirit Airlines
Thu 5/222:07 pmBOG - SAN
2 stops19h 06mSpirit Airlines
Deal found 4/15$431
This Copa Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/79:03 pmSAN - LIM
1 stop13h 22mCopa Airlines
Sun 9/217:00 amLIM - SAN
1 stop12h 50mCopa Airlines
Deal found 4/14$445
This CheapOair deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2910:30 pmSAN - BOG
1 stop18h 45mMultiple Airlines
Mon 6/22:07 pmBOG - SAN
2 stops19h 06mMultiple Airlines
Deal found 4/15$480
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/111:56 pmSAN - MDE
1 stop21h 19mMultiple Airlines
Sat 5/242:13 pmMDE - SAN
2 stops29h 50mMultiple Airlines
Deal found 4/14$503
This United deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1110:38 amSAN - BOG
2 stops16h 16mUnited Airlines
Mon 9/1512:14 amBOG - SAN
1 stop15h 50mUnited Airlines
Deal found 4/14$513
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2710:30 pmSAN - BOG
2 stops19h 28mDelta
Fri 5/3010:45 amBOG - SAN
2 stops13h 35mDelta
Deal found 4/15$517
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/78:10 amSAN - BOG
1 stop12h 20mAmerican Airlines
Mon 5/1212:25 amBOG - SAN
1 stop22h 21mAmerican Airlines
Deal found 4/14$521
This Copa Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/298:58 pmSAN - GIG
1 stop23h 17mCopa Airlines
Fri 9/125:05 amGIG - SAN
1 stop16h 45mCopa Airlines
Deal found 4/13$527

Cheapflights Fare Finder

Customize your flight search to find flights from San Diego to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2025.
Use the filters below to find and compare flights from San Diego to South America that are best for you.

Fly from

San Diego

Fly to

South America

Route

Depart

Return

Price

San DiegoMedellín

SAN - MDE

SANMDE

San Diego

Sun 7/20

8:58 pm-2:15 pm

1 stop15h 17m

Medellín Jose Maria Cordova Intl

Sun 7/27

9:15 am-5:44 pm

1 stop10h 29m

$403

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Wed 7/2

8:58 pm-10:10 am

1 stop11h 12m

Bogotá El Dorado

Mon 7/7

8:35 am-5:44 pm

1 stop11h 09m

$403

San DiegoCartagena

SAN - CTG

SANCTG

San Diego

Wed 9/24

9:03 pm-8:22 am

1 stop9h 19m

Cartagena Rafael Nunez

Mon 9/29

6:20 am-5:50 pm

1 stop13h 30m

$408

San DiegoMedellín

SAN - MDE

SANMDE

San Diego

Sun 5/11

6:58 pm-1:15 pm

2 stops16h 17m

Medellín Jose Maria Cordova Intl

Sat 5/24

2:13 pm-7:13 am

2 stops19h 00m

$417

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Thu 5/15

6:58 pm-1:05 pm

2 stops16h 07m

Bogotá El Dorado

Thu 5/22

2:07 pm-7:13 am

2 stops19h 06m

$431

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Thu 5/29

10:30 pm-7:15 pm

1 stop18h 45m

Bogotá El Dorado

Mon 6/2

2:07 pm-7:13 am

2 stops19h 06m

$480

San DiegoMedellín

SAN - MDE

SANMDE

San Diego

Sun 5/11

1:56 pm-1:15 pm

1 stop21h 19m

Medellín Jose Maria Cordova Intl

Sat 5/24

2:13 pm-6:03 pm

2 stops29h 50m

$503

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Tue 5/27

6:15 am-7:20 pm

1 stop11h 05m

Bogotá El Dorado

Sun 6/1

12:14 am-9:17 am

1 stop11h 03m

$513

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Tue 5/27

10:30 pm-7:58 pm

2 stops19h 28m

Bogotá El Dorado

Fri 5/30

10:45 am-10:20 pm

2 stops13h 35m

$517

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Wed 5/7

8:10 am-10:30 pm

1 stop12h 20m

Bogotá El Dorado

Mon 5/12

12:25 am-8:46 pm

1 stop22h 21m

$521

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/15

Showing 1-10 of 60 results
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Best time to book a flight from San Diego to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to South America

What is the cheapest month to book a flight from San Diego to South America?

Currently, May is the cheapest month in which you can book a flight from San Diego to South America (average of $359). Flying from San Diego to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to SA?

Find hourly flight availability from San Diego to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 15, 2025.

When flying from San Diego to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 15, 2025.
8.0
Very good

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good
8.0
Very good

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Diego to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Diego to South America?

    Located just 2.6 mi from the city center, San Diego (SAN) is the airport most travelers will use when flying to South America from San Diego.

  • What are the cheapest airlines to fly from San Diego to South America one-way?

    The cheapest airlines for a one-way flight from San Diego to South America are Copa Airlines ($185), Spirit Airlines ($218), and American Airlines ($233).

  • What are the most popular routes from San Diego to South America?

  • Can I find deals for flights from San Diego to South America that include hotel bookings?

    Yes. In addition to deals on San Diego to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to South America.

  • Can I find deals for business class flights from San Diego to South America?

    Yes. Cheapflights offers flight deals from San Diego to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to South America?

    Currently, May is the cheapest month in which you can book a flight from San Diego to South America (average of $359). Flying from San Diego to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for San Diego to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 8 airlines flying from San Diego to South America

Discover the top 8 airlines that operate flights from San Diego to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$395Average$926FlexibilityNo cancel feeOn-time69%
Spirit AirlinesCheapest$406Average$491FlexibilityNo cancel feeOn-time65%
Copa AirlinesCheapest$444Average$819FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$449Average$947FlexibilityNo cancel feeOn-time81%
DeltaCheapest$449Average$1,001FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$467Average$1,025FlexibilityNo cancel feeOn-time71%
GOLCheapest$819Average$1,038FlexibilityNo cancel feeOn-time74%
Air CanadaCheapest$985Average$1,084FlexibilityNo cancel feeOn-time67%

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