What are the cheapest airlines to fly from Washington, D.C. Reagan-National Airport to South America one-way?

$123 is the cheapest one-way deal found within the past few days, from LATAM Airlines. You may also be able to find cheap deals on United Airlines and Delta, with prices starting from $148 and $153, respectively.

What are the most popular routes from Washington, D.C. Reagan-National Airport to South America?

The most popular route from Washington, D.C. Reagan-National Airport to South America is Washington, D.C. Reagan-National - Lima J Chavez Intl. You may also consider Washington, D.C. Reagan-National - Medellín Jose Maria Cordova Intl or Washington, D.C. Reagan-National - Bogotá El Dorado.

What are the most popular airlines that fly from Washington, D.C. Reagan-National Airport to South America?

The most popular airlines flying from Washington, D.C. Reagan-National Airport to South America are American Airlines, Delta and LATAM Airlines. Something to consider prior to booking your flight.

What is the cheapest month to fly from Washington, D.C. Reagan-National Airport to South America?

Our data shows that November tends to be the cheapest month to fly to South America from Washington, D.C. Reagan-National Airport. Users have commonly found prices around $790 for the month, but tickets can be as low as $493. Due to multiple factors, prepare for potentially higher prices in December.

Can I find deals for flights from Reagan-National to South America that include hotel bookings?

Yes. In addition to deals on Reagan-National to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Reagan-National to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Reagan-National to South America.

Can I find deals for business class flights from Reagan-National to South America?

Yes. Cheapflights offers flight deals from Reagan-National to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$341+ Flights from Washington, D.C. Reagan-National Airport to South America

Q: How far in advance should I book a flight from Washington, D.C. Reagan-National Airport to South America?

To save up to 16% on this flight, we recommend booking at least 42 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Washington, D.C. Reagan-National Airport to South America from $573 1-2 weeks out and tickets from $573 for flights departing within the next 72 hours.

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Reagan-National to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Reagan-National to South America

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$296 (Delta)
One-way from	$123 (LATAM Airlines)
Popular in	December
Cheapest in	November
Average price	$794

Provider with most accurate pricing for Washington, D.C. (WAS)-Sao Paulo (SAO) flight deals.

Search Deals

Provider most trusted by Cheapflights users for Washington, D.C. (WAS)-Sao Paulo (SAO) flights.

Search Deals

From Washington, D.C. Reagan-National to South America

Search Deals

One-way flight from Washington, D.C. Reagan-National to South America

Search Deals

Highest demand for flights based on searches. 14% potential increase in price ($130 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease ($40 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

Search Deals

Find flight deals from Reagan-National to South America

Cheapest flights from Reagan-National to South America
Explore the most affordable flight options available from Reagan-National to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 15, 2025.

mar. 5/136:00 amDCA - CTG

1 stop8h 19mDelta

sáb. 5/172:34 pmCTG - DCA

1 stop8h 09mDelta

Deal found 4/15

$296

vie. 5/308:45 pmDCA - CTG

1 stop16h 40mAmerican Airlines

vie. 6/61:25 pmCTG - DCA

1 stop8h 43mAmerican Airlines

Deal found 4/15

$299

mié. 9/107:00 amDCA - CTG

2 stops24h 02mLATAM Airlines

lun. 9/159:05 pmCTG - DCA

2 stops23h 59mLATAM Airlines

Deal found 4/15

$332

jue. 5/2911:10 amDCA - BOG

1 stop11h 50mSWISS

jue. 6/511:09 pmBOG - DCA

1 stop10h 18mSWISS

Deal found 4/14

$340

lun. 4/287:59 pmDCA - BOG

1 stop24h 21mUnited Airlines

lun. 5/128:30 amBOG - DCA

1 stop14h 29mUnited Airlines

Deal found 4/15

$351

sáb. 4/2612:25 pmDCA - BOG

1 stop7h 50mLATAM Airlines

mar. 5/610:45 amBOG - DCA

2 stops11h 54mLATAM Airlines

Deal found 4/15

$352

vie. 5/301:55 pmDCA - BOG

1 stop7h 03mDelta

jue. 6/510:15 amBOG - DCA

1 stop10h 45mDelta

Deal found 4/15

$353

lun. 5/1211:05 amDCA - MDE

1 stop11h 05mUnited Airlines

vie. 5/169:45 amMDE - DCA

1 stop24h 51mUnited Airlines

Deal found 4/15

$355

mié. 5/216:59 amDCA - MDE

2 stops16h 41mDelta

mar. 6/109:53 pmMDE - DCA

2 stops22h 44mDelta

Deal found 4/14

$357

dom. 5/256:00 amDCA - BOG

2 stops14h 58mMultiple Airlines

sáb. 5/3110:45 amBOG - DCA

1 stop25h 15mMultiple Airlines

Deal found 4/14

$365

mar. 4/296:59 amDCA - MDE

2 stops14h 29mLATAM Airlines

vie. 5/25:22 amMDE - DCA

2 stops16h 16mLATAM Airlines

Deal found 4/13

$367

vie. 4/2511:54 amDCA - BOG

1 stop11h 36mAmerican Airlines

mar. 4/296:30 amBOG - DCA

1 stop14h 45mAmerican Airlines

Deal found 4/15

$395

Best flights from Reagan-National to South America
Discover carefully curated flight deals from Reagan-National to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated abril 15, 2025.

mar. 5/136:00 amDCA - CTG

1 stop8h 19mDelta

sáb. 5/172:34 pmCTG - DCA

1 stop8h 09mDelta

Deal found 4/15

$296

vie. 5/308:45 pmDCA - CTG

1 stop16h 40mAmerican Airlines

vie. 6/61:25 pmCTG - DCA

1 stop8h 43mAmerican Airlines

Deal found 4/15

$299

jue. 5/2911:10 amDCA - BOG

1 stop11h 50mSWISS

jue. 6/511:09 pmBOG - DCA

1 stop10h 18mSWISS

Deal found 4/14

$340

sáb. 5/241:55 pmDCA - CTG

2 stops12h 15mLATAM Airlines

jue. 5/292:34 pmCTG - DCA

1 stop8h 09mLATAM Airlines

Deal found 4/15

$346

lun. 5/1211:05 amDCA - MDE

1 stop11h 05mUnited Airlines

vie. 5/169:45 amMDE - DCA

1 stop24h 51mUnited Airlines

Deal found 4/15

$355

vie. 5/161:55 pmDCA - BOG

1 stop7h 03mMultiple Airlines

lun. 5/192:55 pmBOG - DCA

1 stop17h 13mMultiple Airlines

Deal found 4/14

$358

sáb. 5/34:35 pmDCA - BOG

1 stop12h 30mAir Canada

dom. 5/49:00 amBOG - DCA

2 stops24h 19mAir Canada

Deal found 4/15

$550

vie. 4/256:05 amDCA - MDE

1 stop7h 20mJetBlue

sáb. 4/261:30 pmMDE - DCA

1 stop8h 16mJetBlue

Deal found 4/15

$553

vie. 5/164:24 pmDCA - GIG

2 stops25h 41mGOL

dom. 6/811:00 pmGIG - DCA

1 stop14h 41mGOL

Deal found 4/14

$684

sáb. 4/2612:25 pmDCA - BOG

1 stop7h 50mLATAM Airlines

mar. 5/610:45 amBOG - DCA

2 stops11h 54mLATAM Airlines

Deal found 4/15

$352

mar. 6/36:59 amDCA - BOG

1 stop10h 36mDelta

mar. 6/105:00 amBOG - DCA

2 stops17h 41mDelta

Deal found 4/14

$353

sáb. 4/2612:45 pmDCA - BOG

1 stop31h 35mUnited Airlines

lun. 5/512:14 amBOG - DCA

1 stop14h 48mUnited Airlines

Deal found 4/14

$361

Last-minute flights from Reagan-National to South America
Discover last-minute flight deals from Reagan-National to South America. Data last updated abril 15, 2025 and is based on user searches.

lun. 4/216:59 amDCA - LIM

1 stop15h 11mMultiple Airlines

mar. 5/610:45 amLIM - DCA

2 stops33h 04mMultiple Airlines

Deal found 4/14

$462

mar. 4/2211:54 amDCA - BOG

1 stop11h 36mAmerican Airlines

mié. 5/76:30 amBOG - DCA

1 stop11h 19mAmerican Airlines

Deal found 4/14

$389

mié. 4/231:55 pmDCA - UIO

1 stop30h 10mLATAM Airlines

vie. 4/257:09 amUIO - DCA

2 stops28h 49mLATAM Airlines

Deal found 4/14

$475

jue. 4/2412:41 pmDCA - LIM

1 stop9h 29mLATAM Airlines

mié. 5/712:05 amLIM - DCA

2 stops21h 37mLATAM Airlines

Deal found 4/14

$397

jue. 4/248:59 amDCA - UIO

1 stop12h 01mDelta

sáb. 5/311:20 pmUIO - DCA

1 stop8h 46mDelta

Deal found 4/14

$415

jue. 4/2411:05 amDCA - BOG

1 stop9h 15mUnited Airlines

dom. 4/2712:14 amBOG - DCA

1 stop22h 45mUnited Airlines

Deal found 4/15

$480

vie. 4/256:00 amDCA - MDE

2 stops17h 25mDelta

vie. 5/27:27 amMDE - DCA

2 stops24h 39mDelta

Deal found 4/15

$363

vie. 4/2512:45 pmDCA - MDE

1 stop9h 25mUnited Airlines

mar. 5/69:45 amMDE - DCA

1 stop11h 30mUnited Airlines

Deal found 4/13

$394

vie. 4/251:55 pmDCA - MDE

2 stops31h 15mMultiple Airlines

lun. 5/59:35 pmMDE - DCA

2 stops22h 14mMultiple Airlines

Deal found 4/14

$404

vie. 4/256:59 amDCA - BOG

1 stop7h 41mLATAM Airlines

jue. 5/12:55 pmBOG - DCA

1 stop30h 43mLATAM Airlines

Deal found 4/15

$412

vie. 4/258:55 pmDCA - MDE

1 stop17h 00mAmerican Airlines

lun. 5/51:50 pmMDE - DCA

1 stop18h 15mAmerican Airlines

Deal found 4/14

$431

vie. 4/256:59 amDCA - MDE

2 stops15h 26mLATAM Airlines

vie. 5/24:22 amMDE - DCA

2 stops17h 16mLATAM Airlines

Deal found 4/15

$455

One-way flights from Reagan-National to South America
Search for one-way flight options from Reagan-National to South America. Find affordable one-way fares based on user searches. Data last updated abril 15, 2025.

jue. 5/226:59 amDCA - CTG

1 stop7h 20mLATAM Airlines

Deal found 4/14

$123

lun. 7/286:00 amDCA - BOG

1 stop14h 20mUnited Airlines

Deal found 4/15

$148

vie. 4/256:00 amDCA - BOG

2 stops11h 15mDelta

Deal found 4/14

$153

mar. 6/36:59 amDCA - BOG

1 stop10h 36mMultiple Airlines

Deal found 4/15

$155

lun. 6/96:30 pmDCA - BOG

2 stops17h 25mLATAM Airlines

Deal found 4/14

$158

jue. 8/147:59 pmDCA - MDE

1 stop9h 43mUnited Airlines

Deal found 4/15

$158

jue. 8/147:00 amDCA - MDE

2 stops27h 00mLATAM Airlines

Deal found 4/14

$163

lun. 5/58:05 amDCA - UIO

1 stop16h 20mUnited Airlines

Deal found 4/15

$165

mar. 5/61:55 pmDCA - UIO

2 stops10h 25mLATAM Airlines

Deal found 4/14

$172

mié. 4/2310:13 amDCA - UIO

2 stops11h 43mAmerican Airlines

Deal found 4/14

$177

sáb. 4/267:35 pmDCA - UIO

2 stops24h 30mDelta

Deal found 4/14

$181

mié. 6/257:59 pmDCA - BOG

1 stop16h 21mAmerican Airlines

Deal found 4/14

$189

Cheapflights Fare Finder

Use the filters below to find and compare flights from Washington, D.C. Reagan-National Airport to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Washington, D.C.Cartagena

DCA - CTG

DCACTG

Washington, D.C. Reagan-National

mar. 5/13

6:00 am-1:19 pm

1 stop8h 19m

Cartagena Rafael Nunez

sáb. 5/17

2:34 pm-11:43 pm

1 stop8h 09m

$296

Washington, D.C.Cartagena

DCA - CTG

DCACTG

Washington, D.C. Reagan-National

vie. 5/30

8:45 pm-12:25 pm

1 stop16h 40m

Cartagena Rafael Nunez

vie. 6/6

1:25 pm-11:08 pm

1 stop8h 43m

$299

Washington, D.C.Cartagena

DCA - CTG

DCACTG

Washington, D.C. Reagan-National

mié. 9/10

7:00 am-6:02 am

2 stops24h 02m

Cartagena Rafael Nunez

lun. 9/15

9:05 pm-10:04 pm

2 stops23h 59m

$332

Washington, D.C.Bogotá

DCA - BOG

DCABOG

Washington, D.C. Reagan-National

jue. 5/29

11:10 am-10:00 pm

1 stop11h 50m

Bogotá El Dorado

jue. 6/5

11:09 pm-10:27 am

1 stop10h 18m

$340

Washington, D.C.Bogotá

DCA - BOG

DCABOG

Washington, D.C. Reagan-National

lun. 4/28

7:59 pm-7:20 pm

1 stop24h 21m

Bogotá El Dorado

lun. 5/12

8:30 am-11:59 pm

1 stop14h 29m

$351

Washington, D.C.Bogotá

DCA - BOG

DCABOG

Washington, D.C. Reagan-National

sáb. 4/26

12:25 pm-7:15 pm

1 stop7h 50m

Bogotá El Dorado

mar. 5/6

10:45 am-11:39 pm

2 stops11h 54m

$352

Washington, D.C.Bogotá

DCA - BOG

DCABOG

Washington, D.C. Reagan-National

vie. 5/30

1:55 pm-7:58 pm

1 stop7h 03m

Bogotá El Dorado

lun. 6/2

1:35 am-12:55 pm

1 stop10h 20m

$353

Washington, D.C.Medellín

DCA - MDE

DCAMDE

Washington, D.C. Reagan-National

lun. 5/12

11:05 am-9:10 pm

1 stop11h 05m

Medellín Jose Maria Cordova Intl

vie. 5/16

9:45 am-11:36 am

1 stop24h 51m

$355

Washington, D.C.Medellín

DCA - MDE

DCAMDE

Washington, D.C. Reagan-National

mié. 5/21

6:59 am-10:40 pm

2 stops16h 41m

Medellín Jose Maria Cordova Intl

dom. 6/8

10:54 pm-10:18 pm

2 stops22h 24m

$357

Washington, D.C.Bogotá

DCA - BOG

DCABOG

Washington, D.C. Reagan-National

dom. 5/25

6:00 am-7:58 pm

2 stops14h 58m

Bogotá El Dorado

sáb. 5/31

10:45 am-1:00 pm

1 stop25h 15m

$365

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/14

Showing 1-10 of 60 results

...

Best time to book a flight from Reagan-National to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Reagan-National with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Washington, D.C. Reagan-National Airport to South America

What is the cheapest month to book a flight from Washington, D.C. Reagan-National Airport to South America?

Currently, May is the cheapest month in which you can book a flight from Washington, D.C. Reagan-National Airport to South America (average of $359). Flying from Washington, D.C. Reagan-National Airport to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DCA to SA?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Washington, D.C. Reagan-National Airport to South America as you normally would.

Rainfall in South America by month

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Azul

8.0

Very good

774 reviews

Reviews

1 / 14

2.0

Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

Azul

8.0

Very good

774 reviews

Azul

8.0

Very good

774 reviews

Reviews

1 / 14

2.0

Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

Delta

8.0

Very good

7,918 reviews

Azul

8.0

Very good

774 reviews

Reviews

1 / 14

2.0

Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

LATAM Airlines

7.5

Good

1,758 reviews

Azul

8.0

Very good

774 reviews

Reviews

1 / 14

2.0

Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

SWISS

7.5

Good

1,578 reviews

Azul

8.0

Very good

774 reviews

Reviews

1 / 14

2.0

Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

United Airlines

7.4

Good

8,658 reviews

Azul

8.0

Very good

774 reviews

Reviews

1 / 14

2.0

Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

Related info for your journey

What are the cheapest airlines to fly from Washington, D.C. Reagan-National Airport to South America one-way?
$123 is the cheapest one-way deal found within the past few days, from LATAM Airlines. You may also be able to find cheap deals on United Airlines and Delta, with prices starting from $148 and $153, respectively.
What are the most popular routes from Washington, D.C. Reagan-National Airport to South America?
The most popular route from Washington, D.C. Reagan-National Airport to South America is Washington, D.C. Reagan-National - Lima J Chavez Intl. You may also consider Washington, D.C. Reagan-National - Medellín Jose Maria Cordova Intl or Washington, D.C. Reagan-National - Bogotá El Dorado.
Can I find deals for flights from Reagan-National to South America that include hotel bookings?
Yes. In addition to deals on Reagan-National to South America flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Reagan-National to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Reagan-National to South America.
Can I find deals for business class flights from Reagan-National to South America?
Yes. Cheapflights offers flight deals from Reagan-National to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Washington, D.C. Reagan-National Airport to South America?
Currently, May is the cheapest month in which you can book a flight from Washington, D.C. Reagan-National Airport to South America (average of $359). Flying from Washington, D.C. Reagan-National Airport to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 8 airlines flying from Reagan-National to South America

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$179	Average$802	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$249	Average$805	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$299	Average$782	FlexibilityNo cancel fee	On-timeN/A
LATAM Airlines	Cheapest$299	Average$738	FlexibilityNo cancel fee	On-time81%
Avianca	Cheapest$336	Average$747	FlexibilityNo cancel fee	On-time71%
Copa Airlines	Cheapest$349	Average$474	FlexibilityNo cancel fee	On-time70%
Air Canada	Cheapest$597	Average$952	FlexibilityNo cancel fee	On-time67%
GOL	Cheapest$633	Average$1,180	FlexibilityNo cancel fee	On-time74%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$123+ Cheap flights from Reagan-National (DCA) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Reagan-National to South America with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Reagan-National to South America

Keep the following information in mind while searching for Reagan-National to South America flight deals. Data was last updated abril 15, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Reagan-National to South America

Cheapest flights from Reagan-National to South AmericaExplore the most affordable flight options available from Reagan-National to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 15, 2025.

Explore the most affordable flight options available from Reagan-National to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 15, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Washington, D.C. Reagan-National Airport to South America that are best for you.

Best time to book a flight from Reagan-National to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Reagan-National with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Washington, D.C. Reagan-National Airport to South America

What is the cheapest month to book a flight from Washington, D.C. Reagan-National Airport to South America?

What is the cheapest time of day to fly from DCA to SA?

Find hourly flight availability from Reagan-National to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 15, 2025.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

Reviews of airlines servicing South America

Related info for your journey

Find useful and relevant information for your journey from Reagan-National to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines to fly from Washington, D.C. Reagan-National Airport to South America one-way?

What are the most popular routes from Washington, D.C. Reagan-National Airport to South America?

Can I find deals for flights from Reagan-National to South America that include hotel bookings?

How can I find direct flights from Reagan-National to South America?

Can I find deals for business class flights from Reagan-National to South America?

What is the cheapest month to book a flight from Washington, D.C. Reagan-National Airport to South America?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Reagan-National to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 8 airlines flying from Reagan-National to South America

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Reagan-National to South America
Explore the most affordable flight options available from Reagan-National to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 15, 2025.