What are the cheapest airlines to fly from Orlando Airport to South America one-way?

One-way options have recently been found by users for as low as $77 on Spirit Airlines. Other airlines that offer cheap prices include Copa Airlines from $111 and LATAM Airlines from $115 one-way.

What are the most popular routes from Orlando Airport to South America?

The most popular flight routes from Orlando Airport to South America are Orlando - Medellín Jose Maria Cordova Intl, Orlando - Bogotá El Dorado and Orlando - Sao Paulo Guarulhos Intl.

What are the cheapest flights from Orlando Airport to South America?

The cheapest flight price from Orlando Airport to South America is $132. On average you can expect to pay $1,148. The most popular route, (Orlando - Medellín Jose Maria Cordova Intl), can usually be booked for $230.

What are the most reliable airlines from Orlando Airport to South America?

The top 3 most reliable airlines when flying from Orlando Airport to South America are Delta (91%), United Airlines (90%) and LATAM Airlines (88%).

What are the most popular airlines that fly from Orlando Airport to South America?

Consider American Airlines, Avianca or Copa Airlines when booking your flight. These represent the most popular airlines when flying from Orlando Airport to South America.

How far in advance should I book a flight from Orlando Airport to South America?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 47 days in advance, which can save you up to 32% on flights from Orlando Airport to South America compared to booking the week you need them. Waiting 47 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $561. For sooner than that we have options available in the next 3 days from $631.

What is the cheapest month to fly from Orlando Airport to South America?

The best pricing can be found in the month of March. Prices to South America from Orlando Airport average $674. You can even find prices in March for less than $674, as users have found deals to South America from as low as $251. The month of December appears to be one of the more expensive times to travel to South America from Orlando Airport. Flying in the targeted month can save you up to 57%.

Can I find deals for flights from Orlando to South America that include hotel bookings?

Yes. In addition to deals on Orlando to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Orlando to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Orlando to South America.

Can I find deals for business class flights from Orlando to South America?

Yes. Cheapflights offers flight deals from Orlando to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$243+ Flights from Orlando Airport to South America

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Cheap flight deals from Orlando to South America

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$229 (Cheapflightsfares)
One-way from	$77 (Cheapflightsfares)
Popular in	December
Cheapest in	March
Average price	$630
Good round-trip deal	$290 or less
Good one-way deal	$135 or less

Provider with most accurate pricing for Orlando (ORL)-Sao Paulo (SAO) flight deals.

Search Deals

Provider most trusted by Cheapflights users for Orlando (ORL)-Sao Paulo (SAO) flights.

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From Orlando to South America

Search Deals

One-way flight from Orlando to South America

Search Deals

Highest demand for flights based on searches. 10% potential increase in price ($81 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease ($36 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

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Price to beat on a round-trip flight from Orlando to South America.

Search Deals

Price to beat on a one-way flight from Orlando to South America.

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Find flight deals from Orlando to South America

Cheapest flights from Orlando to South America
Explore the most affordable flight options available from Orlando to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2025.

Wed 5/148:17 amMCO - CTG

1 stop4h 53mSpirit Airlines

Fri 5/161:15 pmCTG - MCO

1 stop6h 22mSpirit Airlines

Deal found 4/2

$229

Mon 8/183:15 pmMCO - MDE

1 stop9h 02mAvianca

Thu 8/215:59 amMDE - MCO

Nonstop4h 01mAvianca

Deal found 4/2

$256

Wed 5/710:13 amMCO - MDE

Nonstop3h 45mSpirit Airlines

Sun 5/111:53 pmMDE - MCO

Nonstop3h 59mSpirit Airlines

Deal found 4/1

$257

Fri 4/255:57 pmMCO - MDE

1 stop15h 21mCopa Airlines

Tue 5/65:06 amMDE - MCO

1 stop6h 26mCopa Airlines

Deal found 4/2

$259

Sat 4/53:26 pmMCO - CTG

1 stop8h 33mCopa Airlines

Thu 4/103:29 pmCTG - MCO

1 stop6h 11mCopa Airlines

Deal found 4/2

$266

Sun 4/275:05 pmMCO - MDE

1 stop13h 55mLATAM Airlines

Mon 6/99:35 pmMDE - MCO

1 stop16h 59mLATAM Airlines

Deal found 4/2

$278

Fri 5/308:55 pmMCO - CTG

1 stop17h 24mDelta

Thu 6/56:01 amCTG - MCO

1 stop8h 34mDelta

Deal found 4/1

$278

Mon 8/255:30 amMCO - BOG

1 stop8h 38mSpirit Airlines

Thu 9/412:52 pmBOG - MCO

Nonstop4h 21mSpirit Airlines

Deal found 4/2

$280

Sat 4/125:57 pmMCO - BOG

1 stop16h 32mCopa Airlines

Mon 4/214:54 amBOG - MCO

1 stop6h 38mCopa Airlines

Deal found 4/2

$281

Thu 5/153:15 pmMCO - BOG

Nonstop3h 59mAvianca

Tue 5/209:20 amBOG - MCO

Nonstop4h 25mAvianca

Deal found 4/2

$282

Sat 4/267:10 amMCO - MDE

2 stops12h 44mDelta

Tue 5/66:01 amMDE - MCO

1 stop8h 34mDelta

Deal found 4/2

$284

Mon 5/59:01 amMCO - CTG

1 stop6h 09mAmerican Airlines

Sat 5/171:25 pmCTG - MCO

2 stops18h 18mAmerican Airlines

Deal found 4/2

$290

Best flights from Orlando to South America
Discover carefully curated flight deals from Orlando to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 3, 2025.

Wed 5/148:17 amMCO - CTG

1 stop4h 53mSpirit Airlines

Fri 5/161:15 pmCTG - MCO

1 stop6h 22mSpirit Airlines

Deal found 4/2

$229

Mon 8/183:15 pmMCO - MDE

1 stop9h 02mAvianca

Thu 8/215:59 amMDE - MCO

Nonstop4h 01mAvianca

Deal found 4/2

$256

Fri 4/255:57 pmMCO - MDE

1 stop15h 21mCopa Airlines

Tue 5/65:06 amMDE - MCO

1 stop6h 26mCopa Airlines

Deal found 4/2

$259

Sun 4/134:58 pmMCO - CTG

1 stop7h 01mMultiple Airlines

Thu 5/11:12 pmCTG - MCO

1 stop7h 41mMultiple Airlines

Deal found 4/2

$275

Sun 4/275:05 pmMCO - MDE

1 stop15h 38mLATAM Airlines

Sat 6/149:43 pmMDE - MCO

1 stop13h 37mLATAM Airlines

Deal found 4/2

$278

Fri 5/308:55 pmMCO - CTG

1 stop17h 24mDelta

Thu 6/56:01 amCTG - MCO

1 stop8h 34mDelta

Deal found 4/1

$278

Fri 4/257:17 pmMCO - CTG

1 stop19h 58mAmerican Airlines

Fri 5/21:35 pmCTG - MCO

2 stops9h 57mAmerican Airlines

Deal found 4/2

$296

Sat 4/267:00 amMCO - MDE

1 stop15h 10mUnited Airlines

Fri 5/99:45 amMDE - MCO

1 stop13h 01mUnited Airlines

Deal found 4/2

$303

Fri 5/99:10 pmMCO - VCP

1 stop12h 30mGOL

Wed 5/285:55 pmVCP - MCO

1 stop24h 10mGOL

Deal found 4/2

$433

Wed 6/410:30 pmMCO - GIG

1 stop13h 15mAzul

Wed 6/115:10 pmGIG - MCO

1 stop28h 20mAzul

Deal found 4/1

$472

Wed 5/710:13 amMCO - MDE

Nonstop3h 45mSpirit Airlines

Sun 5/111:53 pmMDE - MCO

Nonstop3h 59mSpirit Airlines

Deal found 4/1

$257

Mon 4/143:26 pmMCO - CTG

1 stop8h 33mCopa Airlines

Fri 4/186:20 amCTG - MCO

1 stop15h 10mCopa Airlines

Deal found 4/2

$271

Last-minute flights from Orlando to South America
Discover last-minute flight deals from Orlando to South America. Data last updated April 3, 2025 and is based on user searches.

Sat 4/58:05 amMCO - CTG

1 stop15h 54mCopa Airlines

Thu 4/109:38 amCTG - MCO

1 stop12h 02mCopa Airlines

Deal found 4/2

$266

Mon 4/73:26 pmMCO - CLO

1 stop8h 59mCopa Airlines

Fri 4/1811:59 amCLO - MCO

1 stop9h 41mCopa Airlines

Deal found 4/2

$322

Tue 4/85:05 pmMCO - BOG

Nonstop4h 05mMultiple Airlines

Sun 4/201:59 pmBOG - MCO

1 stop6h 54mMultiple Airlines

Deal found 4/2

$294

Tue 4/87:10 amMCO - CLO

2 stops16h 38mLATAM Airlines

Thu 5/87:29 amCLO - MCO

1 stop7h 06mLATAM Airlines

Deal found 4/2

$339

Wed 4/94:25 pmMCO - BOG

Nonstop4h 00mAvianca

Wed 4/239:20 amBOG - MCO

Nonstop4h 25mAvianca

Deal found 4/2

$282

Wed 4/97:00 amMCO - BOG

1 stop15h 17mAmerican Airlines

Wed 4/166:30 amBOG - MCO

1 stop9h 05mAmerican Airlines

Deal found 4/2

$297

Wed 4/911:55 amMCO - BOG

1 stop8h 25mUnited Airlines

Wed 5/712:14 amBOG - MCO

2 stops20h 27mUnited Airlines

Deal found 4/2

$319

Wed 4/95:05 pmMCO - MDE

1 stop16h 22mMultiple Airlines

Wed 4/301:55 pmMDE - MCO

Nonstop3h 57mMultiple Airlines

Deal found 4/2

$332

Thu 4/106:00 amMCO - BOG

1 stop8h 04mSpirit Airlines

Fri 4/181:59 pmBOG - MCO

1 stop6h 54mSpirit Airlines

Deal found 4/2

$292

Fri 4/111:11 pmMCO - MDE

1 stop8h 59mUnited Airlines

Fri 5/169:45 amMDE - MCO

1 stop11h 15mUnited Airlines

Deal found 4/2

$321

Sat 4/125:57 pmMCO - BOG

1 stop16h 32mCopa Airlines

Mon 4/214:54 amBOG - MCO

1 stop6h 38mCopa Airlines

Deal found 4/2

$281

Sat 4/125:05 pmMCO - MDE

1 stop6h 30mDelta

Thu 5/156:32 amMDE - MCO

1 stop8h 03mDelta

Deal found 4/2

$307

One-way flights from Orlando to South America
Search for one-way flight options from Orlando to South America. Find affordable one-way fares based on user searches. Data last updated April 3, 2025.

Sun 5/189:42 pmMCO - CTG

1 stop15h 28mSpirit Airlines

Deal found 4/2

$77

Tue 4/85:57 pmMCO - CTG

1 stop15h 44mCopa Airlines

Deal found 4/2

$111

Sat 5/1710:13 amMCO - MDE

Nonstop3h 45mSpirit Airlines

Deal found 4/2

$112

Thu 6/121:40 pmMCO - MDE

1 stop17h 52mLATAM Airlines

Deal found 4/2

$115

Tue 5/2711:37 amMCO - MDE

1 stop6h 24mCopa Airlines

Deal found 4/2

$116

Sun 4/67:00 amMCO - CTG

1 stop6h 35mAmerican Airlines

Deal found 4/1

$118

Thu 5/85:05 pmMCO - BOG

Nonstop4h 05mLATAM Airlines

Deal found 4/1

$119

Wed 6/111:40 pmMCO - BOG

Nonstop3h 55mDelta

Deal found 3/31

$120

Wed 9/109:00 amMCO - CLO

1 stop7h 58mMultiple Airlines

Deal found 4/2

$120

Thu 4/104:25 pmMCO - BOG

Nonstop4h 00mAvianca

Deal found 4/1

$121

Tue 4/83:26 pmMCO - BOG

1 stop9h 40mCopa Airlines

Deal found 4/1

$122

Tue 4/297:10 amMCO - MDE

2 stops15h 30mDelta

Deal found 4/2

$123

Cheapflights Fare Finder

Use the filters below to find and compare flights from Orlando Airport to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

OrlandoCartagena

MCO - CTG

MCOCTG

Orlando

Wed 5/14

8:17 am-12:10 pm

1 stop4h 53m

Cartagena Rafael Nunez

Fri 5/16

1:15 pm-8:37 pm

1 stop6h 22m

$229

OrlandoMedellín

MCO - MDE

MCOMDE

Orlando

Wed 5/7

10:13 am-12:58 pm

Nonstop3h 45m

Medellín Jose Maria Cordova Intl

Sun 5/11

1:53 pm-6:52 pm

Nonstop3h 59m

$257

OrlandoMedellín

MCO - MDE

MCOMDE

Orlando

Fri 4/25

5:57 pm-8:18 am

1 stop15h 21m

Medellín Jose Maria Cordova Intl

Tue 5/6

5:06 am-12:32 pm

1 stop6h 26m

$259

OrlandoCartagena

MCO - CTG

MCOCTG

Orlando

Mon 4/14

3:26 pm-10:59 pm

1 stop8h 33m

Cartagena Rafael Nunez

Fri 4/18

6:20 am-10:30 pm

1 stop15h 10m

$271

OrlandoCartagena

MCO - CTG

MCOCTG

Orlando

Sun 4/13

4:58 pm-10:59 pm

1 stop7h 01m

Cartagena Rafael Nunez

Thu 5/1

1:12 pm-9:53 pm

1 stop7h 41m

$275

OrlandoMedellín

MCO - MDE

MCOMDE

Orlando

Sun 4/27

5:05 pm-7:43 am

1 stop15h 38m

Medellín Jose Maria Cordova Intl

Sat 6/14

9:43 pm-12:20 pm

1 stop13h 37m

$278

OrlandoCartagena

MCO - CTG

MCOCTG

Orlando

Fri 5/30

8:55 pm-1:19 pm

1 stop17h 24m

Cartagena Rafael Nunez

Thu 6/5

6:01 am-3:35 pm

1 stop8h 34m

$278

OrlandoBogotá

MCO - BOG

MCOBOG

Orlando

Mon 8/25

5:30 am-1:08 pm

1 stop8h 38m

Bogotá El Dorado

Thu 9/4

12:52 pm-6:13 pm

Nonstop4h 21m

$280

OrlandoBogotá

MCO - BOG

MCOBOG

Orlando

Sat 4/12

5:57 pm-9:29 am

1 stop16h 32m

Bogotá El Dorado

Mon 4/21

4:54 am-12:32 pm

1 stop6h 38m

$281

OrlandoBogotá

MCO - BOG

MCOBOG

Orlando

Thu 5/15

3:15 pm-6:14 pm

Nonstop3h 59m

Bogotá El Dorado

Tue 5/20

9:20 am-2:45 pm

Nonstop4h 25m

$282

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/2

Showing 1-10 of 60 results

...

Best time to book a flight from Orlando to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Orlando with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Orlando Airport to South America

What is the cheapest month to book a flight from Orlando Airport to South America?

Currently, May is the cheapest month in which you can book a flight from Orlando Airport to South America (average of $359). Flying from Orlando Airport to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MCO to SA?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Orlando Airport to South America as you normally would.

Weekly flight availability from Orlando Airport to South America

The most flights from MCO to 0SA are scheduled on a Monday (7 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (5 on average).

Rainfall in South America by month

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Azul

8.0

Very good

773 reviews

Reviews

1 / 14

2.0

Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

Azul

8.0

Very good

773 reviews

Azul

8.0

Very good

773 reviews

Reviews

1 / 14

2.0

Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

Delta

8.0

Very good

7,897 reviews

Azul

8.0

Very good

773 reviews

Reviews

1 / 14

2.0

Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

Copa Airlines

7.6

Good

1,400 reviews

Azul

8.0

Very good

773 reviews

Reviews

1 / 14

2.0

Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

LATAM Airlines

7.5

Good

1,754 reviews

Azul

8.0

Very good

773 reviews

Reviews

1 / 14

2.0

Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

Aeromexico

7.5

Good

1,701 reviews

Azul

8.0

Very good

773 reviews

Reviews

1 / 14

2.0

Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

Related info for your journey

What are the cheapest airlines to fly from Orlando Airport to South America one-way?
One-way options have recently been found by users for as low as $77 on Spirit Airlines. Other airlines that offer cheap prices include Copa Airlines from $111 and LATAM Airlines from $115 one-way.
What are the most popular routes from Orlando Airport to South America?
The most popular flight routes from Orlando Airport to South America are Orlando - Medellín Jose Maria Cordova Intl, Orlando - Bogotá El Dorado and Orlando - Sao Paulo Guarulhos Intl.
What are the most reliable airlines from Orlando Airport to South America?
The top 3 most reliable airlines when flying from Orlando Airport to South America are Delta (91%), United Airlines (90%) and LATAM Airlines (88%).
What are the cheapest flights from Orlando Airport to South America?
The cheapest flight price from Orlando Airport to South America is $132. On average you can expect to pay $1,148. The most popular route, (Orlando - Medellín Jose Maria Cordova Intl), can usually be booked for $230.
Can I find deals for flights from Orlando to South America that include hotel bookings?
Yes. In addition to deals on Orlando to South America flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Orlando to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Orlando to South America.
Can I find deals for business class flights from Orlando to South America?
Yes. Cheapflights offers flight deals from Orlando to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Orlando Airport to South America?
Currently, May is the cheapest month in which you can book a flight from Orlando Airport to South America (average of $359). Flying from Orlando Airport to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 10 airlines flying from Orlando to South America

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$185	Average$320	FlexibilityNo cancel fee	On-time65%
Delta	Cheapest$233	Average$581	FlexibilityNo cancel fee	On-timeN/A
Avianca	Cheapest$236	Average$532	FlexibilityNo cancel fee	On-time71%
Copa Airlines	Cheapest$237	Average$601	FlexibilityNo cancel fee	On-time70%
American Airlines	Cheapest$272	Average$625	FlexibilityNo cancel fee	On-time71%
LATAM Airlines	Cheapest$274	Average$614	FlexibilityNo cancel fee	On-time81%
United Airlines	Cheapest$302	Average$919	FlexibilityNo cancel fee	On-time69%
Azul	Cheapest$322	Average$658	FlexibilityNo cancel fee	On-time82%
GOL	Cheapest$472	Average$770	FlexibilityNo cancel fee	On-time74%
Aerolineas Argentinas	Cheapest$939	Average$1,073	FlexibilityNo cancel fee	On-time59%

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$77+ Cheap flights from Orlando (MCO) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Orlando to South America with Cheapflights

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2. Select your favorite providers

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Cheap flight deals from Orlando to South America

Keep the following information in mind while searching for Orlando to South America flight deals. Data was last updated April 3, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Orlando to South America

Cheapest flights from Orlando to South AmericaExplore the most affordable flight options available from Orlando to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2025.

Explore the most affordable flight options available from Orlando to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Orlando Airport to South America that are best for you.

Best time to book a flight from Orlando to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Orlando with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Orlando Airport to South America

What is the cheapest month to book a flight from Orlando Airport to South America?

What is the cheapest time of day to fly from MCO to SA?

Find hourly flight availability from Orlando to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 3, 2025.

Weekly flight availability from Orlando Airport to South America

Explore weekly flight availability from Orlando to South America. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 3, 2025.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

Reviews of airlines servicing South America

Related info for your journey

Find useful and relevant information for your journey from Orlando to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines to fly from Orlando Airport to South America one-way?

What are the most popular routes from Orlando Airport to South America?

What are the most reliable airlines from Orlando Airport to South America?

What are the cheapest flights from Orlando Airport to South America?

Can I find deals for flights from Orlando to South America that include hotel bookings?

How can I find direct flights from Orlando to South America?

Can I find deals for business class flights from Orlando to South America?

What is the cheapest month to book a flight from Orlando Airport to South America?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Orlando to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 10 airlines flying from Orlando to South America

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Cheapest flights from Orlando to South America
Explore the most affordable flight options available from Orlando to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2025.