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$87+ Cheap flights from Ohio to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — BOG
mar. 31 — abr. 71
lun. 3/31
lun. 4/7
1 adult, Economy
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Cheap flight deals from Ohio to South America

Keep the following information in mind while searching for Ohio to South America flight deals. Data was last updated marzo 26, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$246
(Expedia)

One-way from

$87
(FlightHub)

Popular in

December

Cheapest in

February

Average price

$872
Provider with most accurate pricing for Cleveland Hopkins Intl-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Sao Paulo (SAO) flights.
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From Ohio to South America
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One-way flight from Ohio to South America
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Highest demand for flights based on searches. 16% potential increase in price ($209 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Ohio to South America

Cheapest flights from Ohio to South America
Explore the most affordable flight options available from Ohio to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on marzo 26, 2025.

This FlightHub deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/55:00 amDTW - CTG
1 stop8h 07mSpirit Airlines
sáb. 5/101:15 pmCTG - DTW
1 stop10h 12mSpirit Airlines
Deal found 3/25$232
This Cheapflightsfares deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/119:33 pmCMH - BOG
1 stop16h 31mSpirit Airlines
dom. 4/201:59 pmBOG - CMH
1 stop8h 25mSpirit Airlines
Deal found 3/24$282
This eDestinos deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/119:02 pmDTW - MDE
1 stop17h 13mSpirit Airlines
vie. 4/252:14 pmMDE - DTW
1 stop18h 33mSpirit Airlines
Deal found 3/24$315
This Cheapflightsfares deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/259:33 pmCMH - MDE
1 stop16h 42mSpirit Airlines
mié. 5/142:13 pmMDE - CMH
1 stop17h 37mSpirit Airlines
Deal found 3/25$328
This Mytrip deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/295:00 amDTW - MDE
2 stops14h 54mMultiple Airlines
vie. 5/167:48 pmMDE - DTW
2 stops27h 39mMultiple Airlines
Deal found 3/25$341
This Avianca Connect deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/99:55 amCMH - BOG
1 stop9h 04mMultiple Airlines
mar. 6/39:00 amBOG - CMH
1 stop22h 50mMultiple Airlines
Deal found 3/25$344
This Mytrip deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/259:33 pmCMH - MDE
2 stops25h 08mMultiple Airlines
mié. 5/146:00 amMDE - CMH
2 stops25h 50mMultiple Airlines
Deal found 3/25$360
This Mytrip deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/11:56 pmDTW - CTG
3 stops32h 29mMultiple Airlines
vie. 5/96:06 amCTG - DTW
3 stops29h 32mMultiple Airlines
Deal found 3/25$389
This Mytrip deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/96:38 amDTW - BOG
3 stops31h 27mMultiple Airlines
vie. 5/169:28 pmBOG - DTW
3 stops25h 59mMultiple Airlines
Deal found 3/25$414
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/117:18 pmCLE - MDE
1 stop18h 57mSpirit Airlines
vie. 4/182:14 pmMDE - CLE
1 stop26h 59mSpirit Airlines
Deal found 3/25$419
This Cheapflightsfares deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/156:00 amDTW - BOG
1 stop8h 05mSpirit Airlines
lun. 5/192:07 pmBOG - DTW
1 stop9h 20mSpirit Airlines
Deal found 3/25$453
This Mytrip deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/206:00 amDTW - LIM
2 stops20h 45mMultiple Airlines
mié. 5/288:25 pmLIM - DTW
2 stops27h 02mMultiple Airlines
Deal found 3/25$457

Cheapflights Fare Finder

Customize your flight search to find flights from Ohio to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 26, 2025.
Use the filters below to find and compare flights from Ohio to South America that are best for you.

Fly from

Ohio

Fly to

South America

Route

Depart

Return

Price

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

lun. 5/5

5:00 am-12:07 pm

1 stop8h 07m

Cartagena Rafael Nunez

sáb. 5/10

1:15 pm-12:27 am

1 stop10h 12m

$232

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

vie. 4/11

9:33 pm-1:04 pm

1 stop16h 31m

Bogotá El Dorado

dom. 4/20

1:59 pm-11:24 pm

1 stop8h 25m

$282

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

vie. 4/11

9:02 pm-1:15 pm

1 stop17h 13m

Medellín Jose Maria Cordova Intl

vie. 4/25

2:14 pm-9:47 am

1 stop18h 33m

$315

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

vie. 4/25

9:33 pm-1:15 pm

1 stop16h 42m

Medellín Jose Maria Cordova Intl

mié. 5/14

2:13 pm-8:50 am

1 stop17h 37m

$328

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

mar. 4/29

5:00 am-6:54 pm

2 stops14h 54m

Medellín Jose Maria Cordova Intl

vie. 5/16

7:48 pm-12:27 am

2 stops27h 39m

$341

ColumbusBogotá

CMH - BOG

CMHBOG

Columbus

vie. 5/9

9:55 am-5:59 pm

1 stop9h 04m

Bogotá El Dorado

mar. 6/3

9:00 am-8:50 am

1 stop22h 50m

$344

ColumbusMedellín

CMH - MDE

CMHMDE

Columbus

vie. 4/25

9:33 pm-9:41 pm

2 stops25h 08m

Medellín Jose Maria Cordova Intl

mié. 5/14

6:00 am-8:50 am

2 stops25h 50m

$360

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

jue. 5/1

1:56 pm-9:25 pm

3 stops32h 29m

Cartagena Rafael Nunez

vie. 5/9

6:06 am-12:38 pm

3 stops29h 32m

$389

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

vie. 5/9

6:38 am-1:05 pm

3 stops31h 27m

Bogotá El Dorado

vie. 5/16

9:28 pm-12:27 am

3 stops25h 59m

$414

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

vie. 4/11

7:18 pm-1:15 pm

1 stop18h 57m

Medellín Jose Maria Cordova Intl

vie. 4/18

2:14 pm-6:13 pm

1 stop26h 59m

$419

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/25

Showing 1-10 of 60 results
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Best time to book a flight from Ohio to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to South America

What is the cheapest month to book a flight from Ohio to South America?

Currently, May is the cheapest month in which you can book a flight from Ohio to South America (average of $359). Flying from Ohio to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to SA?

Find hourly flight availability from Ohio to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated marzo 26, 2025.

When flying from Ohio to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated marzo 26, 2025.
Delta
8.0
Very good
7,891 reviews

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,891 reviews
Delta
8.0
Very good
7,891 reviews

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,393 reviews
Delta
8.0
Very good
7,891 reviews

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,749 reviews
Delta
8.0
Very good
7,891 reviews

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,608 reviews
Delta
8.0
Very good
7,891 reviews

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
GOL
7.3
Good
1,050 reviews
Delta
8.0
Very good
7,891 reviews

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Ohio to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Ohio to South America one-way?

    The cheapest airlines for a one-way flight from Ohio to South America are Spirit Airlines ($87), Copa Airlines ($239), and Avianca ($264).

  • Can I find deals for flights from Ohio to South America that include hotel bookings?

    Yes. In addition to deals on Ohio to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to South America.

  • Can I find deals for business class flights from Ohio to South America?

    Yes. Cheapflights offers flight deals from Ohio to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to South America?

    Currently, May is the cheapest month in which you can book a flight from Ohio to South America (average of $359). Flying from Ohio to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Ohio to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Ohio to South America

Discover the top 6 airlines that operate flights from Ohio to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$259Average$893FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$262Average$400FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$370Average$815FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$389Average$980FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$400Average$870FlexibilityNo cancel feeOn-time71%
Air CanadaCheapest$744Average$1,014FlexibilityNo cancel feeOn-time67%
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