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South America

$135+ Cheap flights from Myrtle Beach (MYR) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — BOG
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Myrtle Beach to South America

Cheapest flights from Myrtle Beach to South America
Explore the most affordable flight options available from Myrtle Beach to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This KAYAK deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/149:54 amMYR - MDE
2 stops25h 01mSpirit Airlines
Fri 12/192:25 amMDE - MYR
1 stop15h 43mSpirit Airlines
Deal found 12/10$446
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:54 amMYR - LIM
1 stop12h 41mMultiple Airlines
Thu 2/2611:30 pmLIM - MYR
1 stop14h 43mMultiple Airlines
Deal found 12/11$513
This FlightHub deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:54 amMYR - MDE
1 stop15h 34mSpirit Airlines
Mon 1/52:25 amMDE - MYR
1 stop15h 43mSpirit Airlines
Deal found 12/11$518
This Cheapflightsfares deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/139:54 amMYR - BOG
1 stop15h 18mSpirit Airlines
Sun 12/142:17 amBOG - MYR
1 stop15h 31mSpirit Airlines
Deal found 12/11$527
This Mytrip deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:54 amMYR - LIM
1 stop12h 41mSpirit Airlines
Thu 2/2611:30 pmLIM - MYR
2 stops15h 14mSpirit Airlines
Deal found 12/11$538
This Cheapflightsfares deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/149:54 amMYR - BOG
1 stop15h 18mSpirit Airlines
Fri 12/192:17 amBOG - MYR
1 stop15h 51mSpirit Airlines
Deal found 12/10$640
This Mytrip deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/149:54 amMYR - BOG
1 stop15h 18mMultiple Airlines
Sat 12/2010:00 pmBOG - MYR
2 stops20h 08mMultiple Airlines
Deal found 12/10$668
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:01 pmMYR - LIM
2 stops13h 09mAmerican Airlines
Wed 2/2512:45 amLIM - MYR
2 stops13h 43mAmerican Airlines
Deal found 12/11$693
This KAYAK deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/129:54 amMYR - CLO
1 stop28h 17mSpirit Airlines
Sun 12/143:20 pmCLO - MYR
1 stop26h 28mSpirit Airlines
Deal found 12/10$763
This Cheapflightsfares deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:00 amMYR - LIM
1 stop14h 20mLATAM Airlines
Thu 2/2611:40 pmLIM - MYR
1 stop18h 18mLATAM Airlines
Deal found 12/11$782
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:46 pmMYR - CTG
2 stops19h 44mAmerican Airlines
Wed 12/318:00 amCTG - MYR
2 stops25h 20mAmerican Airlines
Deal found 12/10$792
This Cheapflightsfares deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/139:54 amMYR - BOG
1 stop15h 18mSpirit Airlines
Fri 1/22:17 amBOG - MYR
1 stop15h 51mSpirit Airlines
Deal found 12/10$857

Find flight deals from Myrtle Beach to South America

Keep the following information in mind while searching for Myrtle Beach to South America flight deals. Data was last updated December 12, 2025.

Round-trip from

$315
(KAYAK)

One-way from

$135
(Kiwi.com)
From Myrtle Beach Intl to South America
Search Deals
One-way flight from Myrtle Beach Intl to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Myrtle Beach to South America that are best for you.

Fly from

Myrtle Beach

Fly to

South America

Route

Depart

Return

Price

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Thu 2/19

9:10 am-2:13 pm

1 stop29h 03m

Medellín Jose Maria Cordova Intl

Mon 2/23

3:10 pm-8:15 am

1 stop17h 05m

$315

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Thu 2/5

8:15 pm-2:15 pm

1 stop18h 00m

Medellín Jose Maria Cordova Intl

Mon 2/9

3:15 pm-7:20 pm

1 stop28h 05m

$318

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

Sun 2/1

8:15 pm-2:07 pm

1 stop17h 52m

Bogotá El Dorado

Sat 2/7

3:06 pm-7:20 pm

1 stop28h 14m

$338

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Thu 1/29

8:15 pm-2:15 pm

1 stop18h 00m

Medellín Jose Maria Cordova Intl

Mon 2/2

3:15 pm-2:42 pm

2 stops23h 27m

$404

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Thu 1/15

8:15 pm-1:55 pm

2 stops17h 40m

Medellín Jose Maria Cordova Intl

Mon 1/19

2:50 pm-12:12 pm

1 stop21h 22m

$427

Myrtle BeachLima

MYR - LIM

MYRLIM

Myrtle Beach Intl

Wed 1/21

3:39 pm-10:35 pm

2 stops30h 56m

Lima J Chavez Intl

Wed 1/28

11:33 pm-9:04 pm

2 stops21h 31m

$452

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

Tue 3/10

9:10 am-6:10 pm

1 stop10h 00m

Bogotá El Dorado

Mon 3/16

9:15 am-5:39 pm

1 stop7h 24m

$461

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Thu 2/19

9:09 am-6:57 pm

3 stops33h 48m

Medellín Jose Maria Cordova Intl

Mon 2/23

10:48 pm-8:13 am

3 stops33h 25m

$464

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

Mon 2/2

6:00 am-7:30 pm

1 stop13h 30m

Bogotá El Dorado

Thu 2/5

9:00 am-5:59 pm

1 stop8h 59m

$493

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

Tue 3/10

6:58 pm-1:45 pm

2 stops19h 47m

Bogotá El Dorado

Mon 3/16

3:55 pm-9:38 am

1 stop16h 43m

$513

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 46 results
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Best time to book a flight from Myrtle Beach to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to South America

What is the cheapest month to book a flight from Myrtle Beach to South America?

Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to South America (average of $176). Flying from Myrtle Beach to South America in October is currently the most expensive (average of $647). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SA?

Find hourly flight availability from Myrtle Beach to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

One of the essential ways to save on airfare from Myrtle Beach to South America is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 38% on airfare.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated December 12, 2025.
Peruse reviews from past customers who have flown with LATAM Airlines and Spirit Airlines from Myrtle Beach to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,887 reviews

Boarding

7.6

Overall

7.5

Comfort

7.4

Crew

8.1

Food

6.7

Entertainment

7.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Oct 2025

MIA - GRU

Terrible baggage service! Almost lost my connection flight in SP
LATAM Airlines
7.5
Good
1,887 reviews
LATAM Airlines
7.5
Good
1,887 reviews

Boarding

7.6

Overall

7.5

Comfort

7.4

Crew

8.1

Food

6.7

Entertainment

7.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Oct 2025

MIA - GRU

Terrible baggage service! Almost lost my connection flight in SP
Spirit Airlines
6.3
Okay
8,180 reviews
LATAM Airlines
7.5
Good
1,887 reviews

Boarding

7.6

Overall

7.5

Comfort

7.4

Crew

8.1

Food

6.7

Entertainment

7.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Oct 2025

MIA - GRU

Terrible baggage service! Almost lost my connection flight in SP

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to South America?

    Myrtle Beach Intl (MYR), located 2.1 mi from the city center, is the airport you fly out of when you book flights from Myrtle Beach to South America.

  • How long is the flight from Myrtle Beach to South America?

    Spirit Airlines, LATAM Airlines, and United Airlines can get you from Myrtle Beach to South America in just under 13h 30m. Your travel time can differ by up to 19h 30m. There are 2024 mi between Myrtle Beach and South America. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Myrtle Beach to South America?

    When deciding which route to take from Myrtle Beach to South America consider Myrtle Beach Intl - Lima J Chavez Intl, Myrtle Beach Intl - Medellín Jose Maria Cordova Intl or Myrtle Beach Intl - Bogotá El Dorado as they are the most popular.

  • Can I find deals for flights from Myrtle Beach to South America that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to South America.

  • Can I find deals for business class flights from Myrtle Beach to South America?

    Yes. Cheapflights offers flight deals from Myrtle Beach to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to South America?

    Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to South America (average of $176). Flying from Myrtle Beach to South America in October is currently the most expensive (average of $647). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Myrtle Beach to South America

Discover the top 2 airlines that operate flights from Myrtle Beach to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$327Average$395FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$593Average$722FlexibilityNo cancel feeOn-time81%

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