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$140+ Cheap flights from Myrtle Beach (MYR) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — BOG
Feb 27 — Mar 61
Thu 2/27
Thu 3/6
1 adult, Economy
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Cheap flight deals from Myrtle Beach to South America

Keep the following information in mind while searching for Myrtle Beach to South America flight deals. Data was last updated February 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$307
(FlightHub)

One-way from

$140
(Kiwi.com)
Provider with most accurate pricing for Myrtle Beach Intl-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Sao Paulo (SAO) flights.
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From Myrtle Beach Intl to South America
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One-way flight from Myrtle Beach Intl to South America
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Find flight deals from Myrtle Beach to South America

Cheapest flights from Myrtle Beach to South America
Explore the most affordable flight options available from Myrtle Beach to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2025.

This FlightHub deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/410:27 pmMYR - CTG
1 stop14h 40mSpirit Airlines
Tue 4/81:12 pmCTG - MYR
1 stop6h 10mSpirit Airlines
Deal found 2/22$307
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/226:46 pmMYR - BOG
2 stops22h 25mDelta
Sat 3/296:35 amBOG - MYR
2 stops16h 15mDelta
Deal found 2/21$491
This FlightHub deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/226:41 pmMYR - BOG
1 stop19h 23mSpirit Airlines
Sat 3/291:59 pmBOG - MYR
1 stop29h 23mSpirit Airlines
Deal found 2/21$518
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/138:47 pmMYR - CTG
2 stops18h 13mAmerican Airlines
Sat 7/263:30 pmCTG - MYR
2 stops17h 35mAmerican Airlines
Deal found 2/21$523
This LATAM Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/266:00 amMYR - MDE
2 stops17h 05mLATAM Airlines
Mon 3/3111:53 pmMDE - MYR
2 stops17h 08mLATAM Airlines
Deal found 2/21$649
This FlightHub deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/269:19 amMYR - MDE
2 stops28h 34mSpirit Airlines
Mon 3/312:18 pmMDE - MYR
1 stop26h 18mSpirit Airlines
Deal found 2/21$656
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/141:05 pmMYR - CTG
1 stop24h 47mDelta
Sat 7/262:06 pmCTG - MYR
1 stop19h 05mDelta
Deal found 2/21$688
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/267:00 amMYR - MDE
2 stops14h 16mAmerican Airlines
Sun 3/3012:20 amMDE - MYR
2 stops18h 12mAmerican Airlines
Deal found 2/21$707
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/21:05 pmMYR - LIM
2 stops19h 55mDelta
Sun 6/158:50 amLIM - MYR
2 stops24h 21mDelta
Deal found 2/21$716
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2210:22 amMYR - BOG
2 stops14h 37mAmerican Airlines
Fri 3/2812:10 amBOG - MYR
2 stops12h 54mAmerican Airlines
Deal found 2/21$728
This Mytrip deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/269:45 amMYR - GYE
3 stops25h 32mMultiple Airlines
Fri 3/72:59 pmGYE - MYR
3 stops26h 37mMultiple Airlines
Deal found 2/21$800
This Mytrip deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2612:11 pmMYR - LIM
3 stops40h 31mMultiple Airlines
Tue 3/112:15 pmLIM - MYR
3 stops40h 39mMultiple Airlines
Deal found 2/21$838

Find flights from Myrtle Beach to South America within your budget

Customize your flight search to find flights from Myrtle Beach to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.

Fly from

Myrtle Beach

Fly to

South America

Route

Depart

Return

Price

Myrtle BeachCartagena

MYR - CTG

MYRCTG

Myrtle Beach Intl

Fri 4/4

10:27 pm-12:07 pm

1 stop14h 40m

Cartagena Rafael Nunez

Tue 4/8

1:12 pm-8:22 pm

1 stop6h 10m

$307

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

Sat 3/22

6:46 pm-4:11 pm

2 stops22h 25m

Bogotá El Dorado

Sat 3/29

6:35 am-11:50 pm

2 stops16h 15m

$491

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

Sat 3/22

6:41 pm-1:04 pm

1 stop19h 23m

Bogotá El Dorado

Sat 3/29

1:59 pm-8:22 pm

1 stop29h 23m

$518

Myrtle BeachCartagena

MYR - CTG

MYRCTG

Myrtle Beach Intl

Sun 7/13

8:47 pm-2:00 pm

2 stops18h 13m

Cartagena Rafael Nunez

Sat 7/26

3:30 pm-10:05 am

2 stops17h 35m

$523

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Wed 3/26

6:00 am-10:05 pm

2 stops17h 05m

Medellín Jose Maria Cordova Intl

Mon 3/31

11:53 pm-6:01 pm

2 stops17h 08m

$649

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Wed 3/26

9:19 am-12:53 pm

2 stops28h 34m

Medellín Jose Maria Cordova Intl

Mon 3/31

2:18 pm-5:36 pm

1 stop26h 18m

$656

Myrtle BeachCartagena

MYR - CTG

MYRCTG

Myrtle Beach Intl

Mon 7/14

1:05 pm-12:52 pm

1 stop24h 47m

Cartagena Rafael Nunez

Sat 7/26

2:06 pm-10:11 am

1 stop19h 05m

$688

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Wed 3/26

7:00 am-8:16 pm

2 stops14h 16m

Medellín Jose Maria Cordova Intl

Sun 3/30

12:20 am-7:32 pm

2 stops18h 12m

$707

Myrtle BeachLima

MYR - LIM

MYRLIM

Myrtle Beach Intl

Mon 6/2

1:05 pm-8:00 am

2 stops19h 55m

Lima J Chavez Intl

Sun 6/15

8:50 am-10:11 am

2 stops24h 21m

$716

Myrtle BeachBogotá

MYR - BOG

MYRBOG

Myrtle Beach Intl

Sat 3/22

10:22 am-11:59 pm

2 stops14h 37m

Bogotá El Dorado

Fri 3/28

12:10 am-2:04 pm

2 stops12h 54m

$728

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 16 results
1
2

Best time to book a flight from Myrtle Beach to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Myrtle Beach to South America

Get recent, data-driven insights about flights from Myrtle Beach to South America including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Myrtle Beach to South America?

Currently, May is the cheapest month in which you can book a flight from Myrtle Beach to South America (average of $359). Flying from Myrtle Beach to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SA?

Find hourly flight availability from Myrtle Beach to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 22, 2025.

When flying from Myrtle Beach to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated February 22, 2025.
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,203 reviews
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines
7.5
Good
1,789 reviews
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
8,754 reviews
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Spirit Airlines
6.3
Okay
8,012 reviews
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to South America?

    Myrtle Beach Intl (MYR), located 2.1 mi from the city center, is the airport you fly out of when you book flights from Myrtle Beach to South America.

  • What are the most popular routes from Myrtle Beach to South America?

    When deciding which route to take from Myrtle Beach to South America consider Myrtle Beach Intl - Cartagena Rafael Nunez, Myrtle Beach Intl - Lima J Chavez Intl or Myrtle Beach Intl - Medellín Jose Maria Cordova Intl as they are the most popular.

  • Can I find deals for flights from Myrtle Beach to South America that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to South America.

  • Can I find deals for business class flights from Myrtle Beach to South America?

    Yes. Cheapflights offers flight deals from Myrtle Beach to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to South America?

    Currently, May is the cheapest month in which you can book a flight from Myrtle Beach to South America (average of $359). Flying from Myrtle Beach to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Myrtle Beach to South America

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Top 2 airlines flying from Myrtle Beach to South America

Discover the top 2 airlines that operate flights from Myrtle Beach to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$278Average$477FlexibilityNo cancel feeOn-time65%
DeltaCheapest$691Average$907FlexibilityNo cancel feeOn-timeN/A
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