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South America

$124+ Cheap flights from Missouri to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/7. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BOG
Jan 22 — Jan 291
Wed 1/22
Wed 1/29
1 adult, Economy
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Cheap flight deals from Missouri to South America

Discover tips and strategies to find the most affordable flight options for your journey from Missouri (USMO) to South America (0SA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 17, 2025.

Round-trip from

$342
(Kiwi.com)

One-way from

$124
(Mytrip)
From Missouri to South America
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One-way flight from Missouri to South America
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Find flight deals from Missouri to South America

Cheapest flights from Missouri to South America
Explore the most affordable flight options available from Missouri to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/154:17 pmMCI - BOG
1 stop20h 48mSpirit Airlines
Fri 2/213:00 pmBOG - MCI
1 stop25h 03mSpirit Airlines
Deal found 1/16$342
This Kiwi.com deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/55:05 pmSTL - BOG
1 stop18h 40mMultiple Airlines
Sat 2/81:46 pmBOG - STL
1 stop10h 45mMultiple Airlines
Deal found 1/16$360
This FlightHub deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/214:17 pmMCI - MDE
2 stops20h 42mSpirit Airlines
Thu 2/272:54 pmMDE - MCI
2 stops25h 09mSpirit Airlines
Deal found 1/16$360
This FlightHub deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/43:48 pmSTL - BOG
1 stop17h 38mSpirit Airlines
Mon 2/103:06 pmBOG - STL
1 stop24h 37mSpirit Airlines
Deal found 1/16$383
This Mytrip deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/214:17 pmMCI - MDE
2 stops20h 42mMultiple Airlines
Thu 2/276:00 amMDE - MCI
3 stops29h 35mMultiple Airlines
Deal found 1/16$453
This Mytrip deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/154:17 pmMCI - BOG
3 stops30h 00mMultiple Airlines
Fri 2/213:00 pmBOG - MCI
2 stops20h 35mMultiple Airlines
Deal found 1/16$465
This United Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/176:25 pmMCI - MDE
2 stops26h 40mUnited Airlines
Tue 4/89:45 amMDE - MCI
1 stop12h 34mUnited Airlines
Deal found 1/16$467
This KAYAK deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/96:00 amMCI - MDE
2 stops25h 37mLATAM Airlines
Wed 10/154:02 amMDE - MCI
2 stops19h 51mLATAM Airlines
Deal found 1/16$486
This American Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/136:38 pmMCI - MDE
2 stops18h 34mAmerican Airlines
Thu 5/12:15 pmMDE - MCI
1 stop8h 48mAmerican Airlines
Deal found 1/15$487
This Copa Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/58:15 amSTL - BOG
2 stops13h 48mCopa Airlines
Tue 2/1111:39 amBOG - STL
2 stops23h 45mCopa Airlines
Deal found 1/16$553
This FlightHub deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/43:48 pmSTL - LIM
1 stop30h 00mSpirit Airlines
Mon 2/1011:56 pmLIM - STL
1 stop15h 47mSpirit Airlines
Deal found 1/16$559
This Delta deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/227:00 amMCI - MDE
2 stops16h 00mDelta
Sat 4/59:32 amMDE - MCI
2 stops14h 25mDelta
Deal found 1/16$561

Find flights from Missouri to South America within your budget

Customize your flight search to find flights from Missouri to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 17, 2025.

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Route

Depart

Return

Price

Kansas CityBogotá

MCI - BOG

MCIBOG

Kansas City

Sat 2/15

4:17 pm-2:05 pm

1 stop20h 48m

Bogotá El Dorado

Fri 2/21

3:00 pm-3:03 pm

1 stop25h 03m

$342

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

Wed 2/5

5:05 pm-12:45 pm

1 stop18h 40m

Bogotá El Dorado

Sat 2/8

1:46 pm-11:31 pm

1 stop10h 45m

$360

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Fri 2/21

4:17 pm-1:59 pm

2 stops20h 42m

Medellín Jose Maria Cordova Intl

Thu 2/27

2:54 pm-3:03 pm

2 stops25h 09m

$360

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

Tue 2/4

3:48 pm-10:26 am

1 stop17h 38m

Bogotá El Dorado

Mon 2/10

3:06 pm-2:43 pm

1 stop24h 37m

$383

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Fri 2/21

4:17 pm-1:59 pm

2 stops20h 42m

Medellín Jose Maria Cordova Intl

Thu 2/27

6:00 am-10:35 am

3 stops29h 35m

$453

Kansas CityBogotá

MCI - BOG

MCIBOG

Kansas City

Sat 2/15

4:17 pm-11:17 pm

3 stops30h 00m

Bogotá El Dorado

Fri 2/21

3:00 pm-10:35 am

2 stops20h 35m

$465

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Mon 3/17

6:25 pm-9:05 pm

2 stops26h 40m

Medellín Jose Maria Cordova Intl

Tue 4/8

9:45 am-10:19 pm

1 stop12h 34m

$467

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Sun 4/13

6:38 pm-1:12 pm

2 stops18h 34m

Medellín Jose Maria Cordova Intl

Thu 5/1

2:15 pm-11:03 pm

1 stop8h 48m

$487

St. LouisBogotá

STL - BOG

STLBOG

Lambert-St Louis

Wed 1/29

8:15 am-9:23 am

2 stops24h 08m

Bogotá El Dorado

Tue 2/4

4:42 am-7:09 pm

2 stops15h 27m

$553

St. LouisLima

STL - LIM

STLLIM

Lambert-St Louis

Tue 2/4

3:48 pm-10:48 pm

1 stop30h 00m

Lima J Chavez Intl

Mon 2/10

11:56 pm-2:43 pm

1 stop15h 47m

$559

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/16

Showing 1-10 of 48 results
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Best time to book a flight from Missouri to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to South America

Get recent, data-driven insights about flights from Missouri to South America including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri to South America?

Currently, May is the cheapest month in which you can book a flight from Missouri to South America (average of $359). Flying from Missouri to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SA?

Find hourly flight availability from Missouri to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 17, 2025.

When flying from Missouri to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated January 17, 2025.
Delta
8.0
Very good
8,511 reviews

Food

7.3

Entertainment

7.9

Crew

8.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,511 reviews
Delta
8.0
Very good
8,511 reviews

Food

7.3

Entertainment

7.9

Crew

8.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines
7.7
Good
1,658 reviews
Delta
8.0
Very good
8,511 reviews

Food

7.3

Entertainment

7.9

Crew

8.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines
7.5
Good
1,849 reviews
Delta
8.0
Very good
8,511 reviews

Food

7.3

Entertainment

7.9

Crew

8.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
8,965 reviews
Delta
8.0
Very good
8,511 reviews

Food

7.3

Entertainment

7.9

Crew

8.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

GOL
7.3
Good
1,088 reviews
Delta
8.0
Very good
8,511 reviews

Food

7.3

Entertainment

7.9

Crew

8.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Missouri to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to South America one-way?

    $128 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Avianca and Copa Airlines, with prices starting from $281 and $298, respectively.

  • Can I find deals for flights from Missouri to South America that include hotel bookings?

    Yes. In addition to deals on Missouri to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to South America.

  • Can I find deals for business class flights from Missouri to South America?

    Yes. Cheapflights offers flight deals from Missouri to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to South America?

    Currently, May is the cheapest month in which you can book a flight from Missouri to South America (average of $359). Flying from Missouri to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Missouri to South America

Discover the top 6 airlines that operate flights from Missouri to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$247Average$423FlexibilityNo cancel feeOn-time65%
DeltaCheapest$299Average$840FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$370Average$894FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$389Average$924FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$398Average$891FlexibilityNo cancel feeOn-time71%
Air CanadaCheapest$743Average$956FlexibilityNo cancel feeOn-time67%
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