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$195+ Cheap flights from Mississippi to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/7. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — BOG
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Mississippi to South America

Keep the following information in mind while searching for Mississippi to South America flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$446
(FlightHub)

One-way from

$195
(Mytrip)
Provider with most accurate pricing for Jackson-Evers Intl-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Sao Paulo (SAO) flights.
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From Mississippi to South America
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One-way flight from Mississippi to South America
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Find flight deals from Mississippi to South America

Cheapest flights from Mississippi to South America
Explore the most affordable flight options available from Mississippi to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This FlightHub deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/38:57 amMEM - CTG
1 stop27h 10mSpirit Airlines
Sun 4/61:12 pmCTG - MEM
1 stop10h 47mSpirit Airlines
Deal found 2/19$446
This United deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/215:10 pmBTR - CTG
2 stops27h 44mMultiple Airlines
Mon 3/249:35 amCTG - BTR
2 stops32h 16mMultiple Airlines
Deal found 2/19$449
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/72:35 pmMEM - CTG
3 stops44h 32mMultiple Airlines
Mon 3/109:40 pmCTG - MEM
2 stops25h 59mMultiple Airlines
Deal found 2/20$489
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/265:06 amBTR - CTG
2 stops27h 33mUnited Airlines
Wed 4/29:38 amCTG - BTR
2 stops33h 45mUnited Airlines
Deal found 2/19$491
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/266:00 amBTR - CTG
2 stops13h 44mDelta
Wed 4/22:26 pmCTG - BTR
1 stop7h 56mDelta
Deal found 2/19$590
This United deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/36:30 amMEM - CTG
2 stops26h 11mUnited Airlines
Sun 4/69:38 amCTG - MEM
2 stops24h 08mUnited Airlines
Deal found 2/19$605
This LATAM Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/16:00 amMEM - LIM
2 stops16h 00mLATAM Airlines
Tue 7/88:50 amLIM - MEM
2 stops13h 58mLATAM Airlines
Deal found 2/19$645
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/157:00 amMEM - LIM
1 stop14h 05mDelta
Thu 7/318:50 amLIM - MEM
2 stops13h 58mDelta
Deal found 2/20$661
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/263:14 pmMEM - LIM
1 stop31h 46mUnited Airlines
Fri 5/212:45 amLIM - MEM
1 stop13h 16mUnited Airlines
Deal found 2/19$705
This Avianca Connect deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/215:00 amMEM - GRU
2 stops22h 35mMultiple Airlines
Mon 5/261:45 amGRU - MEM
2 stops23h 12mMultiple Airlines
Deal found 2/19$725
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/155:42 pmMEM - LIM
1 stop9h 33mAmerican Airlines
Thu 7/316:50 amLIM - MEM
1 stop17h 20mAmerican Airlines
Deal found 2/20$725
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/78:56 amMEM - LIM
2 stops15h 54mMultiple Airlines
Sat 3/158:25 pmLIM - MEM
3 stops35h 17mMultiple Airlines
Deal found 2/18$757

Find flights from Mississippi to South America within your budget

Customize your flight search to find flights from Mississippi to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Mississippi

Fly to

South America

Route

Depart

Return

Price

MemphisCartagena

MEM - CTG

MEMCTG

Memphis

Thu 4/3

8:57 am-12:07 pm

1 stop27h 10m

Cartagena Rafael Nunez

Sun 4/6

1:12 pm-11:59 pm

1 stop10h 47m

$446

Baton RougeCartagena

BTR - CTG

BTRCTG

Baton Rouge Ryan

Mon 3/10

2:00 pm-7:48 am

2 stops17h 48m

Cartagena Rafael Nunez

Mon 3/24

9:35 am-3:50 pm

2 stops30h 15m

$449

MemphisCartagena

MEM - CTG

MEMCTG

Memphis

Fri 3/7

2:35 pm-12:07 pm

3 stops44h 32m

Cartagena Rafael Nunez

Mon 3/10

9:40 pm-11:39 pm

2 stops25h 59m

$489

Baton RougeCartagena

BTR - CTG

BTRCTG

Baton Rouge Ryan

Wed 3/26

5:06 am-8:39 am

2 stops27h 33m

Cartagena Rafael Nunez

Wed 4/2

9:38 am-7:23 pm

2 stops33h 45m

$491

Baton RougeCartagena

BTR - CTG

BTRCTG

Baton Rouge Ryan

Fri 4/11

6:22 pm-12:35 pm

2 stops18h 13m

Cartagena Rafael Nunez

Mon 4/14

3:15 pm-12:36 pm

2 stops21h 21m

$569

Baton RougeCartagena

BTR - CTG

BTRCTG

Baton Rouge Ryan

Wed 3/26

6:00 am-7:44 pm

2 stops13h 44m

Cartagena Rafael Nunez

Wed 4/2

2:26 pm-10:22 pm

1 stop7h 56m

$590

MemphisCartagena

MEM - CTG

MEMCTG

Memphis

Thu 4/3

6:30 am-8:41 am

2 stops26h 11m

Cartagena Rafael Nunez

Sun 4/6

9:38 am-9:46 am

2 stops24h 08m

$605

MemphisLima

MEM - LIM

MEMLIM

Memphis

Tue 7/1

6:00 am-10:00 pm

2 stops16h 00m

Lima J Chavez Intl

Mon 7/7

12:05 am-6:16 pm

2 stops18h 11m

$645

MemphisLima

MEM - LIM

MEMLIM

Memphis

Sun 6/15

7:00 am-9:05 pm

1 stop14h 05m

Lima J Chavez Intl

Thu 7/31

8:50 am-10:48 pm

2 stops13h 58m

$661

MemphisLima

MEM - LIM

MEMLIM

Memphis

Sat 4/26

3:14 pm-11:00 pm

1 stop31h 46m

Lima J Chavez Intl

Fri 5/2

12:45 am-2:01 pm

1 stop13h 16m

$705

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 33 results
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Best time to book a flight from Mississippi to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Mississippi to South America

Get recent, data-driven insights about flights from Mississippi to South America including ideal travel times, pricing trends, and more.

What is the cheapest time of day to fly from MS to SA?

Find hourly flight availability from Mississippi to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated February 20, 2025.
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,219 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines
7.5
Good
1,795 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
8,765 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Air Canada
7.0
Good
8,748 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Mississippi to South America that include hotel bookings?

    Yes. In addition to deals on Mississippi to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South America.

  • Can I find deals for business class flights from Mississippi to South America?

    Yes. Cheapflights offers flight deals from Mississippi to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to South America?

    Currently, May is the cheapest month in which you can book a flight from Mississippi to South America (average of $359). Flying from Mississippi to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to South America

Discover the top 2 airlines that operate flights from Mississippi to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$583Average$699FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$685Average$741FlexibilityNo cancel feeOn-time71%
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