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South America

$302+ Cheap flights from Mississippi to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/17. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — BOG
abr. 27 — may. 41
dom. 4/27
dom. 5/4
1 adult, Economy
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Cheap flight deals from Mississippi to South America

Keep the following information in mind while searching for Mississippi to South America flight deals. Data was last updated abril 22, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$559
(United Airlines)

One-way from

$302
(Kiwi.com)
Provider with most accurate pricing for Jackson-Evers Intl-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Sao Paulo (SAO) flights.
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From Mississippi to South America
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One-way flight from Mississippi to South America
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Find flight deals from Mississippi to South America

Cheapest flights from Mississippi to South America
Explore the most affordable flight options available from Mississippi to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 22, 2025.

This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/65:14 pmMEM - PEI
3 stops28h 18mMultiple Airlines
vie. 6/1310:20 amPEI - MEM
2 stops21h 20mMultiple Airlines
Deal found 4/22$526
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/1112:04 pmJAN - BOG
1 stop16h 50mUnited Airlines
sáb. 9/1312:14 amBOG - JAN
1 stop15h 53mUnited Airlines
Deal found 4/22$559
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/106:59 pmJAN - BOG
2 stops15h 56mDelta
lun. 7/145:00 amBOG - JAN
2 stops18h 19mDelta
Deal found 4/22$563
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/127:00 amMEM - LIM
1 stop16h 00mUnited Airlines
vie. 11/141:50 amLIM - MEM
1 stop17h 14mUnited Airlines
Deal found 4/22$645
This LATAM Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/123:35 pmMEM - LIM
2 stops14h 50mLATAM Airlines
vie. 11/1412:10 amLIM - MEM
2 stops21h 19mLATAM Airlines
Deal found 4/22$665
This Avianca Connect deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/265:00 amMEM - LIM
2 stops20h 45mMultiple Airlines
mié. 7/302:50 amLIM - MEM
2 stops20h 07mMultiple Airlines
Deal found 4/22$673
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/85:10 amJAN - BOG
2 stops16h 07mAmerican Airlines
mié. 5/1412:25 amBOG - JAN
1 stop15h 05mAmerican Airlines
Deal found 4/22$712
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/69:16 amMEM - GRU
2 stops28h 04mMultiple Airlines
jue. 6/123:05 amGRU - MEM
2 stops30h 35mMultiple Airlines
Deal found 4/21$722
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/95:14 pmMEM - GIG
2 stops21h 16mMultiple Airlines
lun. 6/166:10 amGIG - MEM
2 stops30h 36mMultiple Airlines
Deal found 4/21$738
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/46:00 amMEM - LIM
2 stops14h 15mDelta
vie. 7/1112:05 amLIM - MEM
2 stops20h 21mDelta
Deal found 4/22$749
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/215:05 pmMEM - SCL
1 stop12h 55mDelta
lun. 10/2712:25 amSCL - MEM
2 stops19h 52mDelta
Deal found 4/22$754
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/111:43 amMEM - PEI
2 stops35h 41mUnited Airlines
dom. 7/66:17 amPEI - MEM
2 stops39h 57mUnited Airlines
Deal found 4/22$760

Cheapflights Fare Finder

Customize your flight search to find flights from Mississippi to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 22, 2025.
Use the filters below to find and compare flights from Mississippi to South America that are best for you.

Fly from

Mississippi

Fly to

South America

Route

Depart

Return

Price

MemphisPereira

MEM - PEI

MEMPEI

Memphis

vie. 6/6

5:14 pm-9:32 pm

3 stops28h 18m

Pereira Matecana

vie. 6/13

10:20 am-7:40 am

2 stops21h 20m

$526

JacksonBogotá

JAN - BOG

JANBOG

Jackson-Evers Intl

jue. 9/11

12:04 pm-4:54 am

1 stop16h 50m

Bogotá El Dorado

sáb. 9/13

12:14 am-4:07 pm

1 stop15h 53m

$559

JacksonBogotá

JAN - BOG

JANBOG

Jackson-Evers Intl

jue. 7/10

6:59 pm-10:55 am

2 stops15h 56m

Bogotá El Dorado

lun. 7/14

5:00 am-11:19 pm

2 stops18h 19m

$563

MemphisLima

MEM - LIM

MEMLIM

Memphis

dom. 10/12

7:00 am-11:00 pm

1 stop16h 00m

Lima J Chavez Intl

vie. 11/14

1:50 am-6:04 pm

1 stop17h 14m

$645

MemphisLima

MEM - LIM

MEMLIM

Memphis

dom. 10/12

3:35 pm-6:25 am

2 stops14h 50m

Lima J Chavez Intl

vie. 11/14

12:10 am-8:29 pm

2 stops21h 19m

$665

MemphisLima

MEM - LIM

MEMLIM

Memphis

sáb. 7/26

5:00 am-1:45 am

2 stops20h 45m

Lima J Chavez Intl

mié. 7/30

2:50 am-10:57 pm

2 stops20h 07m

$673

JacksonBogotá

JAN - BOG

JANBOG

Jackson-Evers Intl

jue. 5/8

5:10 am-9:17 pm

2 stops16h 07m

Bogotá El Dorado

mié. 5/14

12:25 am-3:30 pm

1 stop15h 05m

$712

MemphisSao Paulo

MEM - GRU

MEMGRU

Memphis

vie. 6/6

9:16 am-3:20 pm

2 stops28h 04m

Sao Paulo Guarulhos Intl

jue. 6/12

3:05 am-7:40 am

2 stops30h 35m

$722

MemphisRio de Janeiro

MEM - GIG

MEMGIG

Memphis

lun. 6/9

5:14 pm-4:30 pm

2 stops21h 16m

Rio de Janeiro–Galeão Intl

lun. 6/16

6:10 am-10:46 am

2 stops30h 36m

$738

MemphisLima

MEM - LIM

MEMLIM

Memphis

vie. 7/4

5:55 pm-5:00 am

1 stop11h 05m

Lima J Chavez Intl

vie. 7/11

12:05 am-6:16 pm

2 stops18h 11m

$749

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Showing 1-10 of 34 results
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Best time to book a flight from Mississippi to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to South America

What is the cheapest month to book a flight from Mississippi to South America?

Currently, May is the cheapest month in which you can book a flight from Mississippi to South America (average of $359). Flying from Mississippi to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to SA?

Find hourly flight availability from Mississippi to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 22, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated abril 22, 2025.
Delta
8.0
Very good
7,920 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,920 reviews
Delta
8.0
Very good
7,920 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,764 reviews
Delta
8.0
Very good
7,920 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,683 reviews
Delta
8.0
Very good
7,920 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,920 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Air Canada
7.0
Good
9,179 reviews
Delta
8.0
Very good
7,920 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Mississippi to South America that include hotel bookings?

    Yes. In addition to deals on Mississippi to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South America.

  • Can I find deals for business class flights from Mississippi to South America?

    Yes. Cheapflights offers flight deals from Mississippi to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to South America?

    Currently, May is the cheapest month in which you can book a flight from Mississippi to South America (average of $359). Flying from Mississippi to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to South America

Discover the top 2 airlines that operate flights from Mississippi to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$528Average$658FlexibilityNo cancel feeOn-time69%
DeltaCheapest$583Average$674FlexibilityNo cancel feeOn-timeN/A

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