South America

$311+ Cheap flights from Mississippi to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/17. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — BOG
Jan 26 — Feb 21
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Cheap flight deals from Mississippi to South America

Discover tips and strategies to find the most affordable flight options for your journey from Mississippi (USMS) to South America (0SA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$488
(Kiwi.com)

One-way from

$311
(American Airlines)
From Mississippi to South America
One-way flight from Mississippi to South America

Find flight deals from Mississippi to South America

Cheapest flights from Mississippi to South America
Explore the most affordable flight options available from Mississippi to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/68:42 amMEM - CTG
1 stop27h 25mMultiple Airlines
Thu 3/131:12 pmCTG - MEM
1 stop10h 25mMultiple Airlines
Deal found 1/20$488
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1012:10 pmJAN - BOG
1 stop7h 36mDelta
Fri 8/12:55 pmBOG - JAN
1 stop17h 33mDelta
Deal found 1/20$545
This CheapOair deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/68:02 pmMEM - CTG
2 stops16h 05mSpirit Airlines
Thu 3/131:12 pmCTG - MEM
1 stop10h 25mSpirit Airlines
Deal found 1/20$567
This United deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/36:30 amMEM - CTG
2 stops26h 11mUnited Airlines
Sun 4/69:38 amCTG - MEM
2 stops36h 37mUnited Airlines
Deal found 1/20$573
This Avianca Connect deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/208:57 amMEM - LIM
2 stops16h 53mMultiple Airlines
Tue 4/12:50 amLIM - MEM
2 stops15h 59mMultiple Airlines
Deal found 1/20$683
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/35:48 amMEM - CTG
1 stop6h 42mAmerican Airlines
Sun 4/61:35 pmCTG - MEM
2 stops19h 18mAmerican Airlines
Deal found 1/19$691
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/206:00 amMEM - LIM
2 stops15h 45mDelta
Wed 4/29:05 amLIM - MEM
2 stops14h 12mDelta
Deal found 1/20$705
This LATAM Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/37:16 pmMEM - CTG
1 stop17h 55mLATAM Airlines
Sun 4/62:26 pmCTG - MEM
1 stop17h 38mLATAM Airlines
Deal found 1/19$718
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/206:48 pmMEM - LIM
1 stop28h 52mUnited Airlines
Tue 4/112:45 amLIM - MEM
2 stops45h 29mUnited Airlines
Deal found 1/20$745
This SmartFares deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/236:00 amMEM - LIM
2 stops33h 05mLATAM Airlines
Sun 6/14:00 pmLIM - MEM
2 stops30h 51mLATAM Airlines
Deal found 1/20$746
This Delta deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1210:12 amMEM - CTG
2 stops13h 33mDelta
Mon 2/175:37 amCTG - MEM
2 stops13h 40mDelta
Deal found 1/19$768
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/102:16 pmJAN - BOG
1 stop7h 44mAmerican Airlines
Thu 7/311:55 amBOG - JAN
2 stops16h 07mAmerican Airlines
Deal found 1/20$778

Find flights from Mississippi to South America within your budget

Customize your flight search to find flights from Mississippi to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

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Fly to

Any airport

Route

Depart

Return

Price

MemphisCartagena

MEM - CTG

MEMCTG

Memphis

Thu 3/6

8:42 am-1:07 pm

1 stop27h 25m

Cartagena Rafael Nunez

Thu 3/13

1:12 pm-11:37 pm

1 stop10h 25m

$488

JacksonBogotá

JAN - BOG

JANBOG

Jackson-Evers Intl

Sat 5/10

12:10 pm-7:46 pm

1 stop7h 36m

Bogotá El Dorado

Fri 8/1

2:55 pm-8:28 am

1 stop17h 33m

$545

MemphisCartagena

MEM - CTG

MEMCTG

Memphis

Thu 3/6

8:02 pm-1:07 pm

2 stops16h 05m

Cartagena Rafael Nunez

Thu 3/13

1:12 pm-11:37 pm

1 stop10h 25m

$567

MemphisCartagena

MEM - CTG

MEMCTG

Memphis

Thu 4/3

11:42 am-8:41 am

2 stops20h 59m

Cartagena Rafael Nunez

Sun 4/6

9:38 am-10:15 pm

2 stops36h 37m

$573

MemphisLima

MEM - LIM

MEMLIM

Memphis

Thu 3/20

8:57 am-1:50 am

2 stops16h 53m

Lima J Chavez Intl

Tue 4/1

2:50 am-6:49 pm

2 stops15h 59m

$683

MemphisCartagena

MEM - CTG

MEMCTG

Memphis

Thu 4/3

5:48 am-12:30 pm

1 stop6h 42m

Cartagena Rafael Nunez

Sun 4/6

1:35 pm-8:53 am

2 stops19h 18m

$691

MemphisLima

MEM - LIM

MEMLIM

Memphis

Thu 3/20

6:00 am-9:45 pm

2 stops15h 45m

Lima J Chavez Intl

Wed 4/2

9:05 am-11:17 pm

2 stops14h 12m

$705

MemphisCartagena

MEM - CTG

MEMCTG

Memphis

Thu 4/3

7:16 pm-1:11 pm

1 stop17h 55m

Cartagena Rafael Nunez

Sun 4/6

2:26 pm-8:04 am

1 stop17h 38m

$718

MemphisLima

MEM - LIM

MEMLIM

Memphis

Thu 3/20

6:48 pm-11:40 pm

1 stop28h 52m

Lima J Chavez Intl

Tue 4/1

12:45 am-10:14 pm

2 stops45h 29m

$745

MemphisLima

MEM - LIM

MEMLIM

Memphis

Fri 5/23

6:00 am-3:05 pm

2 stops33h 05m

Lima J Chavez Intl

Sun 6/1

4:00 pm-10:51 pm

2 stops30h 51m

$746

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 38 results
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Best time to book a flight from Mississippi to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Mississippi to South America

Get recent, data-driven insights about flights from Mississippi to South America including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Mississippi to South America?

Currently, May is the cheapest month in which you can book a flight from Mississippi to South America (average of $359). Flying from Mississippi to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to SA?

Find hourly flight availability from Mississippi to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated January 21, 2025.
8.0
Very good
8,521 reviews

Comfort

8.0

Crew

8.6

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

8.0
Very good
8,521 reviews
8.0
Very good
8,521 reviews

Comfort

8.0

Crew

8.6

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

7.5
Good
1,858 reviews
8.0
Very good
8,521 reviews

Comfort

8.0

Crew

8.6

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

7.4
Good
8,985 reviews
8.0
Very good
8,521 reviews

Comfort

8.0

Crew

8.6

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

7.2
Good
10,000 reviews
8.0
Very good
8,521 reviews

Comfort

8.0

Crew

8.6

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

7.0
Good
8,635 reviews
8.0
Very good
8,521 reviews

Comfort

8.0

Crew

8.6

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • Can I find deals for flights from Mississippi to South America that include hotel bookings?

    Yes. In addition to deals on Mississippi to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South America.

  • Can I find deals for business class flights from Mississippi to South America?

    Yes. Cheapflights offers flight deals from Mississippi to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to South America?

    Currently, May is the cheapest month in which you can book a flight from Mississippi to South America (average of $359). Flying from Mississippi to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Mississippi to South America

Discover the top 2 airlines that operate flights from Mississippi to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$583Average$683FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$685Average$741FlexibilityNo cancel feeOn-time71%
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