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South America

$328+ Cheap flights from McAllen (MFE) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/20. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — BOG
Apr 9 — Apr 161
Wed 4/9
Wed 4/16
1 adult, Economy
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Cheap flight deals from McAllen to South America

Keep the following information in mind while searching for McAllen to South America flight deals. Data was last updated April 4, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$515
(Delta)

One-way from

$328
(United Airlines)
Provider with most accurate pricing for McAllen Miller Intl-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for McAllen Miller Intl-Sao Paulo (SAO) flights.
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From McAllen Miller Intl to South America
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One-way flight from McAllen Miller Intl to South America
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Find flight deals from McAllen to South America

Cheapest flights from McAllen to South America
Explore the most affordable flight options available from McAllen to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 4, 2025.

This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/245:15 pmMFE - BOG
2 stops20h 25mDelta
Tue 8/52:55 pmBOG - MFE
2 stops21h 10mDelta
Deal found 4/4$515
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/248:06 pmMFE - BOG
1 stop26h 24mAmerican Airlines
Tue 8/512:25 pmBOG - MFE
2 stops20h 14mAmerican Airlines
Deal found 4/4$605
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/287:00 amMFE - CTG
2 stops25h 41mUnited Airlines
Fri 5/29:38 amCTG - MFE
2 stops51h 49mUnited Airlines
Deal found 4/3$656
This United deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/247:25 pmMFE - BOG
1 stop9h 29mUnited Airlines
Tue 8/58:30 amBOG - MFE
1 stop15h 04mUnited Airlines
Deal found 4/4$738
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2212:33 pmMFE - GRU
2 stops18h 27mDelta
Fri 5/3010:05 amGRU - MFE
2 stops27h 48mDelta
Deal found 4/3$903
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/47:00 amMFE - GRU
2 stops48h 30mUnited Airlines
Sat 5/109:50 pmGRU - MFE
1 stop20h 12mUnited Airlines
Deal found 4/3$919
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/157:00 amMFE - GRU
2 stops23h 20mAmerican Airlines
Sun 7/1310:00 pmGRU - MFE
1 stop23h 26mAmerican Airlines
Deal found 4/3$993
This Mytrip deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/152:15 pmMFE - GRU
2 stops33h 55mMultiple Airlines
Sat 7/124:10 amGRU - MFE
2 stops34h 46mMultiple Airlines
Deal found 4/3$1,019
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/207:00 amMFE - EZE
2 stops22h 15mAmerican Airlines
Wed 5/2810:30 pmEZE - MFE
2 stops25h 00mAmerican Airlines
Deal found 4/3$1,055
This United deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/207:00 amMFE - EZE
1 stop23h 00mUnited Airlines
Wed 5/289:00 pmEZE - MFE
1 stop13h 53mUnited Airlines
Deal found 4/3$1,300
This Air Canada deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/207:00 amMFE - EZE
3 stops29h 30mAir Canada
Wed 5/284:35 pmEZE - MFE
3 stops32h 40mAir Canada
Deal found 4/2$1,314
This United deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/97:00 amMFE - EZE
1 stop23h 00mMultiple Airlines
Wed 4/164:35 pmEZE - MFE
2 stops32h 54mMultiple Airlines
Deal found 4/3$1,543

Cheapflights Fare Finder

Customize your flight search to find flights from McAllen to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2025.
Use the filters below to find and compare flights from McAllen to South America that are best for you.

Fly from

McAllen

Fly to

South America

Route

Depart

Return

Price

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Tue 6/24

5:15 pm-1:40 pm

2 stops20h 25m

Bogotá El Dorado

Tue 8/5

2:55 pm-12:05 pm

2 stops21h 10m

$515

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Tue 6/24

8:06 pm-10:30 pm

1 stop26h 24m

Bogotá El Dorado

Tue 8/5

12:25 pm-8:39 am

2 stops20h 14m

$605

McAllenCartagena

MFE - CTG

MFECTG

McAllen Miller Intl

Mon 4/28

7:00 am-8:41 am

2 stops25h 41m

Cartagena Rafael Nunez

Fri 5/2

9:38 am-1:27 pm

2 stops51h 49m

$656

McAllenBogotá

MFE - BOG

MFEBOG

McAllen Miller Intl

Tue 6/24

7:25 pm-4:54 am

1 stop9h 29m

Bogotá El Dorado

Tue 8/5

8:30 am-11:34 pm

1 stop15h 04m

$738

McAllenSao Paulo

MFE - GRU

MFEGRU

McAllen Miller Intl

Thu 5/22

12:33 pm-9:00 am

2 stops18h 27m

Sao Paulo Guarulhos Intl

Fri 5/30

10:05 am-11:53 am

2 stops27h 48m

$903

McAllenSao Paulo

MFE - GRU

MFEGRU

McAllen Miller Intl

Sun 5/4

7:00 am-9:30 am

2 stops48h 30m

Sao Paulo Guarulhos Intl

Sat 5/10

9:50 pm-4:02 pm

1 stop20h 12m

$919

McAllenSao Paulo

MFE - GRU

MFEGRU

McAllen Miller Intl

Thu 5/15

7:00 am-8:20 am

2 stops23h 20m

Sao Paulo Guarulhos Intl

Sun 7/13

10:00 pm-7:26 pm

1 stop23h 26m

$993

McAllenSao Paulo

MFE - GRU

MFEGRU

McAllen Miller Intl

Thu 5/15

2:15 pm-2:10 am

2 stops33h 55m

Sao Paulo Guarulhos Intl

Sat 7/12

4:10 am-12:56 pm

2 stops34h 46m

$1,019

McAllenBuenos Aires

MFE - EZE

MFEEZE

McAllen Miller Intl

Tue 5/20

7:00 am-7:15 am

2 stops22h 15m

Buenos Aires Ministro Pistarini

Wed 5/28

10:30 pm-9:30 pm

2 stops25h 00m

$1,055

McAllenBuenos Aires

MFE - EZE

MFEEZE

McAllen Miller Intl

Tue 5/20

7:00 am-8:00 am

1 stop23h 00m

Buenos Aires Ministro Pistarini

Wed 5/28

9:00 pm-8:53 am

1 stop13h 53m

$1,300

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/3

Showing 1-10 of 14 results
1
2

Best time to book a flight from McAllen to South America

Have a flexible travel schedule? Discover the best time to fly to South America from McAllen with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from McAllen to South America

What is the cheapest month to book a flight from McAllen to South America?

Currently, May is the cheapest month in which you can book a flight from McAllen to South America (average of $359). Flying from McAllen to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MFE to SA?

Find hourly flight availability from McAllen to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 4, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from McAllen to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 4, 2025.
Delta
8.0
Very good
7,899 reviews

Entertainment

7.9

Crew

8.5

Comfort

8.0

Boarding

8.2

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,899 reviews
Delta
8.0
Very good
7,899 reviews

Entertainment

7.9

Crew

8.5

Comfort

8.0

Boarding

8.2

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,618 reviews
Delta
8.0
Very good
7,899 reviews

Entertainment

7.9

Crew

8.5

Comfort

8.0

Boarding

8.2

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,899 reviews

Entertainment

7.9

Crew

8.5

Comfort

8.0

Boarding

8.2

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Air Canada
7.0
Good
9,040 reviews
Delta
8.0
Very good
7,899 reviews

Entertainment

7.9

Crew

8.5

Comfort

8.0

Boarding

8.2

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from McAllen to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from McAllen to South America?

    Located just 2.0 mi from the city center, McAllen Miller Intl (MFE) is the airport most travelers will use when flying to South America from McAllen.

  • What are the most popular routes from McAllen to South America?

    When deciding which route to take from McAllen to South America consider McAllen Miller Intl - Sao Paulo Guarulhos Intl, McAllen Miller Intl - Buenos Aires Ministro Pistarini or McAllen Miller Intl - Bogotá El Dorado as they are the most popular.

  • Can I find deals for flights from McAllen to South America that include hotel bookings?

    Yes. In addition to deals on McAllen to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from McAllen to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from McAllen to South America.

  • Can I find deals for business class flights from McAllen to South America?

    Yes. Cheapflights offers flight deals from McAllen to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from McAllen to South America?

    Currently, May is the cheapest month in which you can book a flight from McAllen to South America (average of $359). Flying from McAllen to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for McAllen to South America

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Top 3 airlines flying from McAllen to South America

Discover the top 3 airlines that operate flights from McAllen to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$368Average$611FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$429Average$750FlexibilityNo cancel feeOn-time69%
DeltaCheapest$622Average$693FlexibilityNo cancel feeOn-timeN/A

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