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South America

$255+ Cheap flights from Knoxville (TYS) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — BOG
Dec 27 — Jan 31
Fri 12/27
Fri 1/3
1 adult, Economy
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Cheap flight deals from Knoxville to South America

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to South America (0SA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 22, 2024.

Round-trip from

$545
(American Airlines)

One-way from

$255
(Kiwi.com)
From Knoxville McGhee Tyson to South America
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One-way flight from Knoxville McGhee Tyson to South America
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Find flight deals from Knoxville to South America

Cheapest flights from Knoxville to South America
Explore the most affordable flight options available from Knoxville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 22, 2024.

This Mytrip deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/306:00 amTYS - PEI
2 stops26h 30mMultiple Airlines
Wed 2/1210:47 pmPEI - TYS
3 stops24h 22mMultiple Airlines
Deal found 12/20$737
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/259:50 amTYS - GRU
2 stops19h 25mUnited Airlines
Fri 12/2710:25 pmGRU - TYS
1 stop14h 14mUnited Airlines
Deal found 12/21$1,237
This Mytrip deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/259:30 pmTYS - GRU
2 stops30h 10mMultiple Airlines
Fri 12/274:35 pmGRU - TYS
3 stops28h 02mMultiple Airlines
Deal found 12/21$1,348
This eDestinos deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/244:19 pmTYS - LIM
2 stops39h 56mMultiple Airlines
Mon 1/612:30 amLIM - TYS
2 stops16h 04mMultiple Airlines
Deal found 12/21$1,446
This KAYAK deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/313:50 pmTYS - GRU
1 stop11h 50mLATAM Airlines
Fri 1/31:00 amGRU - TYS
2 stops24h 55mLATAM Airlines
Deal found 12/21$1,552
This CheapOair deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/266:25 amTYS - EZE
2 stops21h 50mLATAM Airlines
Fri 12/2710:02 amEZE - TYS
2 stops38h 09mLATAM Airlines
Deal found 12/20$1,632
This KAYAK deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2212:00 pmTYS - LIM
1 stop8h 55mLATAM Airlines
Sun 12/2210:55 pmLIM - TYS
2 stops23h 16mLATAM Airlines
Deal found 12/21$1,813
This United Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2611:50 amTYS - EZE
1 stop17h 30mUnited Airlines
Fri 12/2711:55 pmEZE - TYS
1 stop20h 10mUnited Airlines
Deal found 12/20$1,954
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/246:00 amTYS - LIM
1 stop17h 25mAmerican Airlines
Tue 1/710:55 pmLIM - TYS
1 stop23h 28mAmerican Airlines
Deal found 12/21$1,992
This CheapOair deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/286:57 pmTYS - SCL
2 stops18h 03mLATAM Airlines
Sat 1/411:40 amSCL - TYS
2 stops32h 11mLATAM Airlines
Deal found 12/21$2,021
This United deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/287:00 amTYS - SCL
1 stop23h 50mUnited Airlines
Sat 1/410:45 pmSCL - TYS
1 stop23h 15mUnited Airlines
Deal found 12/21$2,109
This Mytrip deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2612:27 pmTYS - EZE
3 stops24h 18mMultiple Airlines
Fri 12/277:10 pmEZE - TYS
3 stops29h 01mMultiple Airlines
Deal found 12/20$2,133

Find flights from Knoxville to South America within your budget

Customize your flight search to find flights from Knoxville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 22, 2024.

Fly from

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Fly to

Any airport

Route

Depart

Return

Price

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

Tue 2/4

6:20 am-1:30 pm

1 stop7h 10m

Cartagena Rafael Nunez

Sun 2/9

8:35 am-10:23 pm

1 stop13h 48m

$545

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

Tue 2/4

12:08 pm-11:31 pm

2 stops11h 23m

Cartagena Rafael Nunez

Sun 2/9

5:24 am-8:49 pm

2 stops15h 25m

$570

KnoxvilleLima

TYS - LIM

TYSLIM

Knoxville McGhee Tyson

Wed 3/19

10:35 am-11:40 pm

1 stop14h 05m

Lima J Chavez Intl

Tue 3/25

1:30 am-11:54 pm

2 stops21h 24m

$597

KnoxvilleLima

TYS - LIM

TYSLIM

Knoxville McGhee Tyson

Sat 1/18

5:15 pm-10:48 pm

1 stop29h 33m

Lima J Chavez Intl

Thu 1/23

11:56 pm-12:14 pm

1 stop12h 18m

$604

KnoxvilleLima

TYS - LIM

TYSLIM

Knoxville McGhee Tyson

Mon 5/12

4:00 pm-5:00 am

1 stop14h 00m

Lima J Chavez Intl

Wed 5/28

11:20 pm-3:06 pm

1 stop14h 46m

$629

KnoxvilleLima

TYS - LIM

TYSLIM

Knoxville McGhee Tyson

Wed 3/19

7:25 pm-5:00 am

1 stop10h 35m

Lima J Chavez Intl

Wed 3/26

11:55 pm-11:05 am

1 stop10h 10m

$643

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Wed 3/12

7:05 am-7:50 am

1 stop23h 45m

Santiago Arturo Merino Benitez

Mon 3/24

9:45 pm-6:07 pm

1 stop21h 22m

$773

KnoxvilleLima

TYS - LIM

TYSLIM

Knoxville McGhee Tyson

Sat 1/18

5:52 am-11:25 pm

1 stop17h 33m

Lima J Chavez Intl

Wed 1/22

12:45 am-10:23 pm

1 stop21h 38m

$811

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Sun 3/16

12:00 pm-5:57 am

2 stops16h 57m

Santiago Arturo Merino Benitez

Sun 3/23

11:20 pm-6:13 pm

2 stops19h 53m

$1,127

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Sat 3/15

5:51 am-7:55 am

1 stop25h 04m

Santiago Arturo Merino Benitez

Sat 3/22

10:45 pm-10:55 pm

1 stop25h 10m

$1,146

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Showing 1-10 of 16 results
1
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Best time to book a flight from Knoxville to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to South America

Get recent, data-driven insights about flights from Knoxville to South America including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to South America?

Currently, May is the cheapest month in which you can book a flight from Knoxville to South America (average of $359). Flying from Knoxville to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to SA?

Find hourly flight availability from Knoxville to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 22, 2024.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated December 22, 2024.
Delta
8.0
Very good
8,597 reviews

Entertainment

7.9

Food

7.3

Crew

8.6

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,597 reviews
Delta
8.0
Very good
8,597 reviews

Entertainment

7.9

Food

7.3

Crew

8.6

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines
7.7
Good
1,713 reviews
Delta
8.0
Very good
8,597 reviews

Entertainment

7.9

Food

7.3

Crew

8.6

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines
7.5
Good
1,868 reviews
Delta
8.0
Very good
8,597 reviews

Entertainment

7.9

Food

7.3

Crew

8.6

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
9,035 reviews
Delta
8.0
Very good
8,597 reviews

Entertainment

7.9

Food

7.3

Crew

8.6

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,597 reviews

Entertainment

7.9

Food

7.3

Crew

8.6

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to South America?

    If you book a flight to South America from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • What are the cheapest airlines to fly from Knoxville to South America one-way?

    The cheapest airline one-way is Copa Airlines, with whom users have recently found tickets for as low as $365. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Knoxville to South America for a low price.

  • What are the most popular routes from Knoxville to South America?

    Most travelers choose Knoxville McGhee Tyson - Lima J Chavez Intl, Knoxville McGhee Tyson - Buenos Aires Ministro Pistarini or Knoxville McGhee Tyson - Santiago Arturo Merino Benitez when deciding on the best route from Knoxville to South America.

  • Can I find deals for flights from Knoxville to South America that include hotel bookings?

    Yes. In addition to deals on Knoxville to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to South America.

  • Can I find deals for business class flights from Knoxville to South America?

    Yes. Cheapflights offers flight deals from Knoxville to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to South America?

    Currently, May is the cheapest month in which you can book a flight from Knoxville to South America (average of $359). Flying from Knoxville to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Knoxville to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Knoxville to South America

Discover the top 2 airlines that operate flights from Knoxville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 22, 2024.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$391Average$932FlexibilityNo cancel feeOn-time71%
DeltaCheapest$399Average$1,041FlexibilityNo cancel feeOn-timeN/A
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