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$135+ Cheap flights from Indianapolis (IND) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel.
IND — BOG
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Cheap flight deals from Indianapolis to South America

Keep the following information in mind while searching for Indianapolis to South America flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$301
(Mytrip)

One-way from

$135
(Mytrip)

Popular in

April

Cheapest in

March

Average price

$827
Provider with most accurate pricing for Indianapolis-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Sao Paulo (SAO) flights.
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From Indianapolis to South America
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One-way flight from Indianapolis to South America
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Highest demand for flights based on searches. 32% potential increase in price ($647 potential increase over avg. RT price).
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Cheapest flight prices on average. 21% potential price decrease ($239 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Indianapolis to South America

Cheapest flights from Indianapolis to South America
Explore the most affordable flight options available from Indianapolis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This Mytrip deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/26:49 pmIND - CTG
1 stop18h 18mSpirit Airlines
Thu 5/81:15 pmCTG - IND
1 stop10h 08mSpirit Airlines
Deal found 3/26$301
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1210:03 amIND - BOG
1 stop28h 01mSpirit Airlines
Sun 5/41:59 pmBOG - IND
2 stops19h 37mSpirit Airlines
Deal found 3/26$345
This Avianca Connect deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/158:00 amIND - BOG
1 stop10h 59mMultiple Airlines
Wed 5/289:00 amBOG - IND
1 stop14h 23mMultiple Airlines
Deal found 3/27$348
This Cheapflightsfares deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/145:35 amIND - MDE
1 stop8h 25mSpirit Airlines
Fri 4/182:14 pmMDE - IND
1 stop17h 44mSpirit Airlines
Deal found 3/26$357
This Mytrip deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1410:03 amIND - MDE
2 stops36h 45mMultiple Airlines
Fri 4/187:55 amMDE - IND
2 stops24h 03mMultiple Airlines
Deal found 3/26$389
This Mytrip deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/81:15 pmIND - CTG
3 stops42h 00mMultiple Airlines
Sun 5/111:15 pmCTG - IND
1 stop9h 00mMultiple Airlines
Deal found 3/27$392
This Avianca Connect deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/118:00 amIND - CLO
2 stops16h 18mMultiple Airlines
Sun 5/186:23 amCLO - IND
2 stops17h 00mMultiple Airlines
Deal found 3/27$428
This Avianca Connect deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/110:11 amIND - UIO
2 stops13h 14mMultiple Airlines
Fri 5/91:40 amUIO - IND
2 stops21h 43mMultiple Airlines
Deal found 3/26$455
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/711:49 amIND - BOG
2 stops16h 26mDelta
Wed 4/162:55 pmBOG - IND
1 stop8h 33mDelta
Deal found 3/26$493
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/269:00 amIND - BOG
2 stops11h 20mUnited Airlines
Sun 5/412:14 amBOG - IND
1 stop14h 30mUnited Airlines
Deal found 3/27$503
This Mytrip deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/141:54 pmIND - VCP
3 stops28h 11mMultiple Airlines
Mon 4/286:20 amVCP - IND
3 stops33h 29mMultiple Airlines
Deal found 3/26$521
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/125:23 amIND - BOG
1 stop18h 07mAmerican Airlines
Sat 5/312:25 amBOG - IND
1 stop21h 09mAmerican Airlines
Deal found 3/26$521

Cheapflights Fare Finder

Customize your flight search to find flights from Indianapolis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Indianapolis to South America that are best for you.

Fly from

Indianapolis

Fly to

South America

Route

Depart

Return

Price

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

Fri 5/2

6:49 pm-12:07 pm

1 stop18h 18m

Cartagena Rafael Nunez

Thu 5/8

1:15 pm-12:23 am

1 stop10h 08m

$301

IndianapolisBogotá

IND - BOG

INDBOG

Indianapolis

Sat 4/12

10:03 am-1:04 pm

1 stop28h 01m

Bogotá El Dorado

Sun 5/4

1:59 pm-10:36 am

2 stops19h 37m

$345

IndianapolisBogotá

IND - BOG

INDBOG

Indianapolis

Thu 5/15

8:00 am-5:59 pm

1 stop10h 59m

Bogotá El Dorado

Wed 5/28

9:00 am-12:23 am

1 stop14h 23m

$348

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

Mon 4/14

5:35 am-1:00 pm

1 stop8h 25m

Medellín Jose Maria Cordova Intl

Fri 4/18

2:14 pm-8:58 am

1 stop17h 44m

$357

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

Mon 4/14

10:03 am-9:48 pm

2 stops36h 45m

Medellín Jose Maria Cordova Intl

Fri 4/18

7:55 am-8:58 am

2 stops24h 03m

$389

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

Thu 5/8

1:15 pm-6:15 am

3 stops42h 00m

Cartagena Rafael Nunez

Sun 5/11

1:15 pm-11:15 pm

1 stop9h 00m

$392

IndianapolisCali

IND - CLO

INDCLO

Indianapolis

Sun 5/11

8:00 am-11:18 pm

2 stops16h 18m

Cali Alfonso B. Aragon Intl

Sun 5/18

6:23 am-12:23 am

2 stops17h 00m

$428

IndianapolisQuito

IND - UIO

INDUIO

Indianapolis

Thu 5/1

10:11 am-10:25 pm

2 stops13h 14m

Quito Mariscal Sucr

Fri 5/9

1:40 am-12:23 am

2 stops21h 43m

$455

IndianapolisBogotá

IND - BOG

INDBOG

Indianapolis

Mon 4/7

11:49 am-3:15 am

2 stops16h 26m

Bogotá El Dorado

Wed 4/16

2:55 pm-12:28 am

1 stop8h 33m

$493

IndianapolisBogotá

IND - BOG

INDBOG

Indianapolis

Sat 4/26

9:00 am-7:20 pm

2 stops11h 20m

Bogotá El Dorado

Sun 5/4

12:14 am-3:44 pm

1 stop14h 30m

$503

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Showing 1-10 of 53 results
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Best time to book a flight from Indianapolis to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to South America

What is the cheapest month to book a flight from Indianapolis to South America?

Currently, May is the cheapest month in which you can book a flight from Indianapolis to South America (average of $359). Flying from Indianapolis to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to SA?

Find hourly flight availability from Indianapolis to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

When flying from Indianapolis to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated March 28, 2025.
Delta
8.0
Very good
7,896 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,896 reviews
Delta
8.0
Very good
7,896 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,750 reviews
Delta
8.0
Very good
7,896 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.5
Good
1,395 reviews
Delta
8.0
Very good
7,896 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,603 reviews
Delta
8.0
Very good
7,896 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,896 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to South America?

    If you book a flight to South America from Indianapolis, you will be flying from Indianapolis, which is the city’s only airport. Indianapolis (IND) is located 8.3 mi from the center of Indianapolis.

  • What are the cheapest airlines to fly from Indianapolis to South America one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $135. Avianca flights start at $294 while deals on American Airlines start at $352 one-way.

  • What are the most popular routes from Indianapolis to South America?

    The most popular flight routes from Indianapolis to South America are Indianapolis - Medellín Jose Maria Cordova Intl, Indianapolis - Bogotá El Dorado and Indianapolis - Quito Mariscal Sucr.

  • Can I find deals for flights from Indianapolis to South America that include hotel bookings?

    Yes. In addition to deals on Indianapolis to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to South America.

  • Can I find deals for business class flights from Indianapolis to South America?

    Yes. Cheapflights offers flight deals from Indianapolis to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to South America?

    Currently, May is the cheapest month in which you can book a flight from Indianapolis to South America (average of $359). Flying from Indianapolis to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indianapolis to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Indianapolis to South America

Discover the top 5 airlines that operate flights from Indianapolis to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$257Average$633FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$389Average$943FlexibilityNo cancel feeOn-time81%
DeltaCheapest$399Average$942FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$423Average$937FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$633Average$1,072FlexibilityNo cancel feeOn-time69%
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