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$128+ Cheap flights from Indianapolis (IND) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel.
IND — BOG
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Indianapolis to South America

Keep the following information in mind while searching for Indianapolis to South America flight deals. Data was last updated April 17, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$334
(Cheapflightsfares)

One-way from

$128
(Expedia)

Popular in

April

Cheapest in

March

Average price

$3,966
Provider with most accurate pricing for Indianapolis-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Sao Paulo (SAO) flights.
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From Indianapolis to South America
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One-way flight from Indianapolis to South America
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Highest demand for flights based on searches. 31% potential increase in price ($624 potential increase over avg. RT price).
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Cheapest flight prices on average. 21% potential price decrease ($240 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Indianapolis to South America

Cheapest flights from Indianapolis to South America
Explore the most affordable flight options available from Indianapolis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/125:45 amIND - MDE
1 stop8h 13mSpirit Airlines
Tue 5/201:53 pmMDE - IND
1 stop9h 06mSpirit Airlines
Deal found 4/16$334
This Avianca Connect deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/158:15 amIND - CTG
2 stops14h 10mMultiple Airlines
Tue 5/206:55 amCTG - IND
2 stops15h 20mMultiple Airlines
Deal found 4/15$343
This CheapOair deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/118:15 amIND - BOG
1 stop29h 50mSpirit Airlines
Sat 5/172:07 pmBOG - IND
1 stop9h 03mSpirit Airlines
Deal found 4/17$373
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/175:45 amIND - MDE
1 stop8h 13mMultiple Airlines
Sun 5/257:09 amMDE - IND
2 stops15h 06mMultiple Airlines
Deal found 4/17$376
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/88:15 amIND - CTG
1 stop28h 55mSpirit Airlines
Sat 6/141:15 pmCTG - IND
1 stop10h 44mSpirit Airlines
Deal found 4/16$392
This Avianca Connect deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/138:15 amIND - BOG
1 stop10h 44mMultiple Airlines
Mon 5/199:00 amBOG - IND
1 stop13h 15mMultiple Airlines
Deal found 4/16$422
This Avianca Connect deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/18:15 amIND - CLO
2 stops14h 58mMultiple Airlines
Sun 6/84:24 amCLO - IND
2 stops17h 51mMultiple Airlines
Deal found 4/17$490
This LATAM Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/157:15 amIND - CLO
2 stops24h 01mLATAM Airlines
Thu 5/224:08 amCLO - IND
2 stops19h 07mLATAM Airlines
Deal found 4/17$494
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/17:05 amIND - BOG
2 stops13h 45mDelta
Mon 5/57:00 amBOG - IND
2 stops15h 07mDelta
Deal found 4/17$497
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/15:23 amIND - BOG
1 stop18h 07mAmerican Airlines
Sun 5/412:25 amBOG - IND
1 stop21h 01mAmerican Airlines
Deal found 4/17$501
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1311:46 amIND - CTG
2 stops21h 57mUnited Airlines
Fri 5/169:38 amCTG - IND
2 stops37h 17mUnited Airlines
Deal found 4/16$508
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/16:27 amIND - UIO
3 stops25h 33mMultiple Airlines
Sun 8/32:30 amUIO - IND
2 stops30h 16mMultiple Airlines
Deal found 4/17$535

Cheapflights Fare Finder

Customize your flight search to find flights from Indianapolis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Indianapolis to South America that are best for you.

Fly from

Indianapolis

Fly to

South America

Route

Depart

Return

Price

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

Mon 5/12

5:45 am-12:58 pm

1 stop8h 13m

Medellín Jose Maria Cordova Intl

Tue 5/20

1:53 pm-11:59 pm

1 stop9h 06m

$334

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

Thu 5/15

8:15 am-9:25 pm

2 stops14h 10m

Cartagena Rafael Nunez

Tue 5/20

6:55 am-11:15 pm

2 stops15h 20m

$343

IndianapolisBogotá

IND - BOG

INDBOG

Indianapolis

Sun 5/11

8:15 am-1:05 pm

1 stop29h 50m

Bogotá El Dorado

Sat 5/17

2:07 pm-12:10 am

1 stop9h 03m

$373

IndianapolisMedellín

IND - MDE

INDMDE

Indianapolis

Sat 5/17

5:45 am-12:58 pm

1 stop8h 13m

Medellín Jose Maria Cordova Intl

Sun 5/25

7:09 am-11:15 pm

2 stops15h 06m

$376

IndianapolisCartagena

IND - CTG

INDCTG

Indianapolis

Sun 6/8

8:15 am-12:10 pm

1 stop28h 55m

Cartagena Rafael Nunez

Sat 6/14

1:15 pm-12:59 am

1 stop10h 44m

$392

IndianapolisBogotá

IND - BOG

INDBOG

Indianapolis

Tue 5/13

8:15 am-5:59 pm

1 stop10h 44m

Bogotá El Dorado

Mon 5/19

9:00 am-11:15 pm

1 stop13h 15m

$422

IndianapolisCali

IND - CLO

INDCLO

Indianapolis

Sun 6/1

8:15 am-10:13 pm

2 stops14h 58m

Cali Alfonso B. Aragon Intl

Sun 6/8

4:24 am-11:15 pm

2 stops17h 51m

$490

IndianapolisCali

IND - CLO

INDCLO

Indianapolis

Thu 5/15

7:15 am-6:16 am

2 stops24h 01m

Cali Alfonso B. Aragon Intl

Thu 5/22

4:08 am-12:15 am

2 stops19h 07m

$494

IndianapolisBogotá

IND - BOG

INDBOG

Indianapolis

Thu 5/1

7:05 am-7:50 pm

2 stops13h 45m

Bogotá El Dorado

Mon 5/5

7:00 am-11:07 pm

2 stops15h 07m

$497

IndianapolisBogotá

IND - BOG

INDBOG

Indianapolis

Thu 5/1

5:23 am-10:30 pm

1 stop18h 07m

Bogotá El Dorado

Sun 5/4

12:25 am-10:26 pm

1 stop21h 01m

$501

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 53 results
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Best time to book a flight from Indianapolis to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Indianapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to South America

What is the cheapest month to book a flight from Indianapolis to South America?

Currently, May is the cheapest month in which you can book a flight from Indianapolis to South America (average of $359). Flying from Indianapolis to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to SA?

Find hourly flight availability from Indianapolis to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

When flying from Indianapolis to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 17, 2025.
Delta
8.0
Very good
7,916 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,916 reviews
Delta
8.0
Very good
7,916 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,409 reviews
Delta
8.0
Very good
7,916 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,761 reviews
Delta
8.0
Very good
7,916 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
SWISS
7.5
Good
1,580 reviews
Delta
8.0
Very good
7,916 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,667 reviews
Delta
8.0
Very good
7,916 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Indianapolis to South America?

    If you book a flight to South America from Indianapolis, you will be flying from Indianapolis, which is the city’s only airport. Indianapolis (IND) is located 8.3 mi from the center of Indianapolis.

  • What are the cheapest airlines to fly from Indianapolis to South America one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $128. Copa Airlines flights start at $274 while deals on Avianca start at $310 one-way.

  • What are the most popular routes from Indianapolis to South America?

    The most popular flight routes from Indianapolis to South America are Indianapolis - Bogotá El Dorado, Indianapolis - Medellín Jose Maria Cordova Intl and Indianapolis - Lima J Chavez Intl.

  • Can I find deals for flights from Indianapolis to South America that include hotel bookings?

    Yes. In addition to deals on Indianapolis to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indianapolis to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to South America.

  • Can I find deals for business class flights from Indianapolis to South America?

    Yes. Cheapflights offers flight deals from Indianapolis to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indianapolis to South America?

    Currently, May is the cheapest month in which you can book a flight from Indianapolis to South America (average of $359). Flying from Indianapolis to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indianapolis to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Indianapolis to South America

Discover the top 5 airlines that operate flights from Indianapolis to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$260Average$689FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$409Average$939FlexibilityNo cancel feeOn-time81%
DeltaCheapest$426Average$951FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$489Average$980FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$633Average$1,067FlexibilityNo cancel feeOn-time69%

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