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South America

$225+ Cheap flights from Greenville (GSP) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — BOG
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Greenville to South America

Keep the following information in mind while searching for Greenville to South America flight deals. Data was last updated April 17, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$473
(Avianca)

One-way from

$225
(Kiwi.com)
Provider with most accurate pricing for Greenville-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Greenville-Sao Paulo (SAO) flights.
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From Greenville to South America
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One-way flight from Greenville to South America
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Find flight deals from Greenville to South America

Cheapest flights from Greenville to South America
Explore the most affordable flight options available from Greenville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Avianca deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/286:00 amGSP - BOG
1 stop14h 50mMultiple Airlines
Mon 5/511:00 pmBOG - GSP
1 stop9h 52mMultiple Airlines
Deal found 4/17$473
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/85:34 pmGSP - MDE
1 stop12h 08mUnited Airlines
Wed 7/169:45 amMDE - GSP
1 stop11h 15mUnited Airlines
Deal found 4/17$506
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/205:31 amGSP - MDE
2 stops15h 24mAmerican Airlines
Tue 10/285:50 amMDE - GSP
1 stop12h 36mAmerican Airlines
Deal found 4/17$510
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/256:18 pmGSP - BOG
1 stop19h 47mAmerican Airlines
Mon 6/96:30 amBOG - GSP
1 stop12h 12mAmerican Airlines
Deal found 4/16$527
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/255:30 amGSP - BOG
1 stop14h 45mDelta
Mon 6/910:45 amBOG - GSP
2 stops21h 15mDelta
Deal found 4/16$547
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/156:30 amGSP - MDE
2 stops17h 13mDelta
Thu 5/228:02 amMDE - GSP
2 stops14h 50mDelta
Deal found 4/17$557
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/154:33 pmGSP - MDE
2 stops21h 42mMultiple Airlines
Wed 5/2112:10 amMDE - GSP
2 stops40h 16mMultiple Airlines
Deal found 4/17$569
This FlightHub deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/287:30 amGSP - BOG
1 stop12h 45mLATAM Airlines
Tue 7/89:00 amBOG - GSP
1 stop13h 45mLATAM Airlines
Deal found 4/17$620
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/286:50 amGSP - BOG
2 stops23h 04mUnited Airlines
Sun 5/412:14 amBOG - GSP
2 stops21h 46mUnited Airlines
Deal found 4/17$636
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/55:57 amGSP - LIM
1 stop17h 23mAmerican Airlines
Fri 9/126:55 amLIM - GSP
1 stop16h 29mAmerican Airlines
Deal found 4/16$649
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/55:45 amGSP - LIM
2 stops16h 55mDelta
Fri 9/121:30 pmLIM - GSP
2 stops20h 26mDelta
Deal found 4/16$653
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/305:18 pmGSP - UIO
1 stop31h 07mUnited Airlines
Fri 6/61:15 amUIO - GSP
1 stop20h 00mUnited Airlines
Deal found 4/17$667

Cheapflights Fare Finder

Customize your flight search to find flights from Greenville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Greenville to South America that are best for you.

Fly from

Greenville

Fly to

South America

Route

Depart

Return

Price

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Mon 4/28

6:00 am-7:50 pm

1 stop14h 50m

Bogotá El Dorado

Mon 5/5

11:00 pm-9:52 am

1 stop9h 52m

$473

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Tue 7/8

5:34 pm-4:42 am

1 stop12h 08m

Medellín Jose Maria Cordova Intl

Wed 7/16

9:45 am-10:00 pm

1 stop11h 15m

$506

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Sun 5/25

6:18 pm-1:05 pm

1 stop19h 47m

Bogotá El Dorado

Mon 6/9

6:30 am-7:42 pm

1 stop12h 12m

$527

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sun 5/25

6:18 pm-12:50 pm

1 stop19h 32m

Medellín Jose Maria Cordova Intl

Mon 6/9

6:00 am-7:42 pm

1 stop12h 42m

$536

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Sun 5/25

5:30 am-7:15 pm

1 stop14h 45m

Bogotá El Dorado

Sun 6/8

1:35 am-9:41 pm

2 stops19h 06m

$547

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Thu 5/15

6:30 am-10:43 pm

2 stops17h 13m

Medellín Jose Maria Cordova Intl

Thu 5/22

8:02 am-11:52 pm

2 stops14h 50m

$557

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Thu 5/15

4:33 pm-1:15 pm

2 stops21h 42m

Medellín Jose Maria Cordova Intl

Wed 5/21

12:10 am-5:26 pm

2 stops40h 16m

$569

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Sat 6/28

7:30 am-7:15 pm

1 stop12h 45m

Bogotá El Dorado

Tue 7/8

9:00 am-11:45 pm

1 stop13h 45m

$620

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Mon 4/28

6:50 am-4:54 am

2 stops23h 04m

Bogotá El Dorado

Sun 5/4

12:14 am-11:00 pm

2 stops21h 46m

$636

GreenvilleLima

GSP - LIM

GSPLIM

Greenville

Fri 9/5

5:57 am-10:20 pm

1 stop17h 23m

Lima J Chavez Intl

Fri 9/12

6:55 am-12:24 am

1 stop16h 29m

$649

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 42 results
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Best time to book a flight from Greenville to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to South America

What is the cheapest month to book a flight from Greenville to South America?

Currently, May is the cheapest month in which you can book a flight from Greenville to South America (average of $359). Flying from Greenville to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to SA?

Find hourly flight availability from Greenville to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

When flying from Greenville to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 17, 2025.
Delta
8.0
Very good
7,916 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,916 reviews
Delta
8.0
Very good
7,916 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,409 reviews
Delta
8.0
Very good
7,916 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,761 reviews
Delta
8.0
Very good
7,916 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,667 reviews
Delta
8.0
Very good
7,916 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,916 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Greenville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to South America?

    For a flight from Greenville to South America, you will be flying from Greenville. Greenville (GSP) is just 10.4 mi from the center of the city.

  • What are the cheapest airlines to fly from Greenville to South America one-way?

    To fly one-way, consider booking your trip with Copa Airlines, which is currently one of the cheapest options available, starting at $274. American Airlines flights start at $310 while deals on United Airlines start at $318 one-way.

  • What are the most popular routes from Greenville to South America?

    The most popular route from Greenville to South America is Greenville - Medellín Jose Maria Cordova Intl. You may also consider Greenville - Bogotá El Dorado or Greenville - Lima J Chavez Intl.

  • Can I find deals for flights from Greenville to South America that include hotel bookings?

    Yes. In addition to deals on Greenville to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to South America.

  • Can I find deals for business class flights from Greenville to South America?

    Yes. Cheapflights offers flight deals from Greenville to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to South America?

    Currently, May is the cheapest month in which you can book a flight from Greenville to South America (average of $359). Flying from Greenville to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Greenville to South America

Discover the top 3 airlines that operate flights from Greenville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$465Average$701FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$502Average$873FlexibilityNo cancel feeOn-time81%
DeltaCheapest$532Average$972FlexibilityNo cancel feeOn-timeN/A

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