South America

$134+ Cheap flights from Durham, NC to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — BOG
Apr 6 — Apr 131
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Cheap flight deals from Durham to South America

Keep the following information in mind while searching for Durham to South America flight deals. Data was last updated April 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$256
(Copa Airlines)

One-way from

$134
(Avianca Connect)

Popular in

May

Cheapest in

March

Average price

$570
Provider with most accurate pricing for Raleigh-Durham-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for Raleigh-Durham-Sao Paulo (SAO) flights.
From Durham to South America
One-way flight from Durham to South America
Highest demand for flights based on searches. 18% potential increase in price ($169 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($38 potential savings vs. average RT price).
Average for round-trip flights in April 2025

Find flight deals from Durham to South America

Cheapest flights from Durham to South America
Explore the most affordable flight options available from Durham to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2025.

This Copa Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/144:18 pmRDU - BOG
1 stop8h 48mCopa Airlines
Wed 4/234:54 amBOG - RDU
1 stop8h 35mCopa Airlines
Deal found 3/31$256
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/269:59 amRDU - BOG
1 stop10h 16mDelta
Thu 5/87:00 amBOG - RDU
1 stop11h 49mDelta
Deal found 3/31$283
This LATAM Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/277:59 pmRDU - BOG
2 stops21h 16mLATAM Airlines
Thu 5/82:55 pmBOG - RDU
1 stop18h 09mLATAM Airlines
Deal found 3/31$300
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/96:10 amRDU - BOG
1 stop14h 10mUnited Airlines
Fri 5/2312:14 amBOG - RDU
1 stop10h 17mUnited Airlines
Deal found 4/1$303
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2610:21 amRDU - BOG
2 stops11h 56mAmerican Airlines
Sat 5/36:30 amBOG - RDU
1 stop14h 52mAmerican Airlines
Deal found 3/30$322
This FlightHub deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/49:53 pmRDU - CTG
1 stop15h 14mSpirit Airlines
Tue 4/81:12 pmCTG - RDU
1 stop6h 36mSpirit Airlines
Deal found 3/31$331
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/184:19 pmRDU - UIO
1 stop9h 14mCopa Airlines
Thu 5/226:27 pmUIO - RDU
1 stop19h 02mCopa Airlines
Deal found 3/30$349
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/77:20 pmRDU - CTG
2 stops17h 46mAmerican Airlines
Tue 11/112:55 pmCTG - RDU
2 stops18h 10mAmerican Airlines
Deal found 4/1$352
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/46:30 amRDU - MDE
1 stop15h 40mUnited Airlines
Thu 6/129:45 amMDE - RDU
2 stops27h 25mUnited Airlines
Deal found 3/31$354
This LATAM Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/118:20 amRDU - CTG
2 stops23h 07mLATAM Airlines
Mon 9/159:05 pmCTG - RDU
2 stops22h 51mLATAM Airlines
Deal found 3/31$356
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/147:05 amRDU - MDE
2 stops18h 00mDelta
Mon 4/212:48 amMDE - RDU
2 stops15h 59mDelta
Deal found 3/31$374
This Copa Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/74:19 pmRDU - GYE
1 stop8h 18mCopa Airlines
Wed 5/284:28 amGYE - RDU
1 stop9h 01mCopa Airlines
Deal found 3/31$382

Cheapflights Fare Finder

Customize your flight search to find flights from Durham to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2025.
Use the filters below to find and compare flights from Durham to South America that are best for you.

Fly from

Durham

Fly to

South America

Route

Depart

Return

Price

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Mon 4/14

4:18 pm-12:06 am

1 stop8h 48m

Bogotá El Dorado

Wed 4/23

4:54 am-2:29 pm

1 stop8h 35m

$256

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Sat 4/26

9:59 am-7:15 pm

1 stop10h 16m

Bogotá El Dorado

Thu 5/8

7:00 am-7:49 pm

1 stop11h 49m

$283

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Sun 4/27

7:59 pm-4:15 pm

2 stops21h 16m

Bogotá El Dorado

Thu 5/8

2:55 pm-10:04 am

1 stop18h 09m

$300

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Fri 5/9

6:10 am-7:20 pm

1 stop14h 10m

Bogotá El Dorado

Fri 5/23

12:14 am-11:31 am

1 stop10h 17m

$303

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Sat 4/26

10:21 am-9:17 pm

2 stops11h 56m

Bogotá El Dorado

Sat 5/3

6:30 am-10:22 pm

1 stop14h 52m

$322

RaleighQuito

RDU - UIO

RDUUIO

Raleigh-Durham

Sun 5/18

4:19 pm-12:33 am

1 stop9h 14m

Quito Mariscal Sucr

Thu 5/22

6:27 pm-2:29 pm

1 stop19h 02m

$349

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Thu 5/15

8:27 pm-12:25 pm

2 stops16h 58m

Cartagena Rafael Nunez

Thu 5/22

3:10 pm-8:25 am

2 stops16h 15m

$352

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Wed 6/4

6:30 am-9:10 pm

1 stop15h 40m

Medellín Jose Maria Cordova Intl

Thu 6/12

9:45 am-2:10 pm

2 stops27h 25m

$354

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Thu 9/11

8:20 am-6:27 am

2 stops23h 07m

Cartagena Rafael Nunez

Mon 9/15

9:05 pm-8:56 pm

2 stops22h 51m

$356

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Mon 4/14

7:05 am-12:05 am

2 stops18h 00m

Medellín Jose Maria Cordova Intl

Mon 4/21

2:48 am-7:47 pm

2 stops15h 59m

$374

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 60 results
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Best time to book a flight from Durham to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to South America

What is the cheapest month to book a flight from Durham to South America?

Currently, May is the cheapest month in which you can book a flight from Durham to South America (average of $359). Flying from Durham to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SA?

Find hourly flight availability from Durham to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 1, 2025.

When flying from Durham to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 1, 2025.
8.0
Very good

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
8.0
Very good
8.0
Very good

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
8.0
Very good
8.0
Very good

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
8.0
Very good

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
8.0
Very good

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
8.0
Very good

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

Related info for your journey

Find useful and relevant information for your journey from Durham to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from Durham to South America one-way?

    The cheapest airlines for a one-way flight from Durham to South America are Spirit Airlines ($157), United Airlines ($158), and American Airlines ($184).

  • What are the most popular routes from Durham to South America?

  • Can I find deals for flights from Durham to South America that include hotel bookings?

    Yes. In addition to deals on Durham to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to South America.

  • Can I find deals for business class flights from Durham to South America?

    Yes. Cheapflights offers flight deals from Durham to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to South America?

    Currently, May is the cheapest month in which you can book a flight from Durham to South America (average of $359). Flying from Durham to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Durham to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 9 airlines flying from Durham to South America

Discover the top 9 airlines that operate flights from Durham to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$225Average$654FlexibilityNo cancel feeOn-time81%
AviancaCheapest$244Average$669FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$256Average$536FlexibilityNo cancel feeOn-time70%
Spirit AirlinesCheapest$260Average$598FlexibilityNo cancel feeOn-time65%
DeltaCheapest$308Average$793FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$311Average$759FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$316Average$838FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$373Average$563FlexibilityNo cancel feeOn-time62%
GOLCheapest$451Average$667FlexibilityNo cancel feeOn-time74%
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