HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South America

$150+ Cheap flights from Durham, NC to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — BOG
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Durham to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Durham to South America

Keep the following information in mind while searching for Durham to South America flight deals. Data was last updated April 17, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$277
(Copa Airlines)

One-way from

$150
(American Airlines)

Popular in

May

Cheapest in

March

Average price

$565
Provider with most accurate pricing for Raleigh-Durham-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Sao Paulo (SAO) flights.
Search Deals
From Durham to South America
Search Deals
One-way flight from Durham to South America
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($161 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($38 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals

Find flight deals from Durham to South America

Cheapest flights from Durham to South America
Explore the most affordable flight options available from Durham to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Copa Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/144:19 pmRDU - BOG
1 stop8h 47mCopa Airlines
Wed 5/214:54 amBOG - RDU
1 stop8h 35mCopa Airlines
Deal found 4/16$277
This CheapOair deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/27:00 amRDU - BOG
1 stop10h 35mLATAM Airlines
Tue 6/107:00 amBOG - RDU
1 stop11h 15mLATAM Airlines
Deal found 4/16$286
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/96:43 amRDU - BOG
1 stop15h 34mAmerican Airlines
Mon 5/122:10 pmBOG - RDU
1 stop20h 06mAmerican Airlines
Deal found 4/16$288
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/95:25 amRDU - BOG
1 stop14h 50mDelta
Sat 5/246:44 amBOG - RDU
2 stops16h 35mDelta
Deal found 4/16$289
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/135:00 pmRDU - BOG
1 stop12h 54mUnited Airlines
Sun 5/1812:14 amBOG - RDU
1 stop10h 15mUnited Airlines
Deal found 4/16$303
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/198:47 amRDU - CTG
1 stop6h 23mAmerican Airlines
Fri 5/233:10 pmCTG - RDU
1 stop17h 08mAmerican Airlines
Deal found 4/16$319
This FlightHub deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/27:05 amRDU - CTG
2 stops18h 20mLATAM Airlines
Wed 5/76:32 amCTG - RDU
2 stops12h 17mLATAM Airlines
Deal found 4/17$327
This Copa Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/274:22 pmRDU - CTG
1 stop7h 37mCopa Airlines
Wed 9/36:20 amCTG - RDU
1 stop7h 08mCopa Airlines
Deal found 4/16$336
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/14:20 pmRDU - MDE
1 stop19h 35mCopa Airlines
Sun 6/89:42 amMDE - RDU
1 stop27h 47mCopa Airlines
Deal found 4/17$347
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/41:00 pmRDU - MDE
2 stops16h 42mUnited Airlines
Thu 6/129:45 amMDE - RDU
2 stops27h 25mUnited Airlines
Deal found 4/16$355
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/112:19 pmRDU - BOG
1 stop10h 40mMultiple Airlines
Sun 5/112:07 pmBOG - RDU
1 stop18h 05mMultiple Airlines
Deal found 4/17$359
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/211:45 amRDU - BOG
1 stop26h 19mSpirit Airlines
Sun 5/112:07 pmBOG - RDU
1 stop18h 05mSpirit Airlines
Deal found 4/16$364

Cheapflights Fare Finder

Customize your flight search to find flights from Durham to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Durham to South America that are best for you.

Fly from

Durham

Fly to

South America

Route

Depart

Return

Price

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Wed 5/14

4:19 pm-12:06 am

1 stop8h 47m

Bogotá El Dorado

Wed 5/21

4:54 am-2:29 pm

1 stop8h 35m

$277

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Mon 6/2

7:00 am-4:35 pm

1 stop10h 35m

Bogotá El Dorado

Tue 6/10

7:00 am-7:15 pm

1 stop11h 15m

$286

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Fri 5/9

6:43 am-9:17 pm

1 stop15h 34m

Bogotá El Dorado

Mon 5/12

2:10 pm-11:16 am

1 stop20h 06m

$288

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Fri 5/9

5:25 am-7:15 pm

1 stop14h 50m

Bogotá El Dorado

Sat 5/24

6:44 am-12:19 am

2 stops16h 35m

$289

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Tue 5/13

5:00 pm-4:54 am

1 stop12h 54m

Bogotá El Dorado

Sun 5/18

12:14 am-11:29 am

1 stop10h 15m

$303

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Mon 5/19

8:47 am-2:10 pm

1 stop6h 23m

Cartagena Rafael Nunez

Fri 5/23

3:10 pm-9:18 am

1 stop17h 08m

$319

RaleighCartagena

RDU - CTG

RDUCTG

Raleigh-Durham

Fri 5/2

7:05 am-12:25 am

2 stops18h 20m

Cartagena Rafael Nunez

Wed 5/7

6:32 am-7:49 pm

2 stops12h 17m

$327

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Sun 6/1

4:20 pm-10:55 am

1 stop19h 35m

Medellín Jose Maria Cordova Intl

Sun 6/8

9:42 am-2:29 pm

1 stop27h 47m

$347

RaleighMedellín

RDU - MDE

RDUMDE

Raleigh-Durham

Wed 6/4

1:00 pm-4:42 am

2 stops16h 42m

Medellín Jose Maria Cordova Intl

Thu 6/12

9:45 am-2:10 pm

2 stops27h 25m

$355

RaleighBogotá

RDU - BOG

RDUBOG

Raleigh-Durham

Thu 5/1

12:19 pm-9:59 pm

1 stop10h 40m

Bogotá El Dorado

Sun 5/11

2:07 pm-9:12 am

1 stop18h 05m

$359

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Durham to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to South America

What is the cheapest month to book a flight from Durham to South America?

Currently, May is the cheapest month in which you can book a flight from Durham to South America (average of $359). Flying from Durham to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SA?

Find hourly flight availability from Durham to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

When flying from Durham to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 17, 2025.
Azul
8.0
Very good
774 reviews

Boarding

8.1

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Azul
8.0
Very good
774 reviews
Azul
8.0
Very good
774 reviews

Boarding

8.1

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Delta
8.0
Very good
7,917 reviews
Azul
8.0
Very good
774 reviews

Boarding

8.1

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Copa Airlines
7.6
Good
1,409 reviews
Azul
8.0
Very good
774 reviews

Boarding

8.1

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
LATAM Airlines
7.5
Good
1,761 reviews
Azul
8.0
Very good
774 reviews

Boarding

8.1

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
United Airlines
7.4
Good
8,667 reviews
Azul
8.0
Very good
774 reviews

Boarding

8.1

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

Related info for your journey

Find useful and relevant information for your journey from Durham to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Durham to South America one-way?

    The cheapest airlines for a one-way flight from Durham to South America are American Airlines ($150), United Airlines ($153), and Copa Airlines ($155).

  • What are the most popular routes from Durham to South America?

    While some choose either Raleigh-Durham - Bogotá El Dorado or Raleigh-Durham - Lima J Chavez Intl, Raleigh-Durham - Medellín Jose Maria Cordova Intl is the most popular route from Durham to South America.

  • Can I find deals for flights from Durham to South America that include hotel bookings?

    Yes. In addition to deals on Durham to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to South America.

  • Can I find deals for business class flights from Durham to South America?

    Yes. Cheapflights offers flight deals from Durham to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to South America?

    Currently, May is the cheapest month in which you can book a flight from Durham to South America (average of $359). Flying from Durham to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Durham to South America

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to John F Kennedy Intl flights
Raleigh to John F Kennedy Intl flights
Raleigh to LaGuardia flights
Raleigh to Seattle flights
Charlotte to LaGuardia flights
Raleigh to Newark flights
Charlotte to Boston flights
Charlotte to Newark flights
Charlotte to Denver flights
Raleigh to O'Hare Intl flights
Charlotte to Hobby flights
Raleigh to Miami flights
Raleigh to Denver flights
Charlotte to O'Hare Intl flights
Charlotte to Seattle flights
Charlotte to Las Vegas flights
Raleigh to Las Vegas flights
Charlotte to George Bush Intcntl flights
Charlotte to Fort Lauderdale flights
Charlotte to Heathrow flights
Raleigh to Orlando flights
Raleigh to San Francisco flights
Raleigh to Luis Munoz Marin Intl flights
Raleigh to Boston flights
Raleigh to Nashville flights
Raleigh to Hobby flights
Charlotte to Dallas/Fort Worth flights
Charlotte to Orlando flights
Charlotte to Cancún flights
Raleigh to Dallas/Fort Worth flights
Raleigh to Los Angeles flights
Raleigh to Fort Lauderdale flights
Raleigh to Atlanta flights
Charlotte to Miami flights
Raleigh to Heathrow flights
Raleigh to Charles de Gaulle flights
Charlotte to Dulles Intl flights
Norfolk to O'Hare Intl flights
Raleigh to George Bush Intcntl flights
Charlotte to Sky Harbor Intl flights
Raleigh to Islip flights
Charlotte to Detroit flights
Greensboro to John F Kennedy Intl flights
Charlotte to Leonardo da Vinci/Fiumicino flights
Greensboro to LaGuardia flights
Charlotte to Salt Lake City flights
Norfolk to Hobby flights
Charlotte to Los Angeles flights
Raleigh to Austin flights
Charlotte to Luis Munoz Marin Intl flights

Top 9 airlines flying from Durham to South America

Discover the top 9 airlines that operate flights from Durham to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$232Average$698FlexibilityNo cancel feeOn-time69%
AviancaCheapest$244Average$669FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$256Average$556FlexibilityNo cancel feeOn-time70%
Spirit AirlinesCheapest$261Average$676FlexibilityNo cancel feeOn-time65%
LATAM AirlinesCheapest$282Average$666FlexibilityNo cancel feeOn-time81%
DeltaCheapest$292Average$803FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$315Average$869FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$373Average$562FlexibilityNo cancel feeOn-time62%
GOLCheapest$451Average$748FlexibilityNo cancel feeOn-time74%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.