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South America

$378+ Cheap flights from Des Moines (DSM) to South America

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — BOG
Jan 26 — Feb 21
Sun 1/26
Sun 2/2
1 adult, Economy
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Cheap flight deals from Des Moines to South America

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to South America (0SA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$543
(LATAM Airlines)

One-way from

$449
(eDestinos)
From Des Moines to South America
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One-way flight from Des Moines to South America
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Find flight deals from Des Moines to South America

Cheapest flights from Des Moines to South America
Explore the most affordable flight options available from Des Moines to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This LATAM Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/235:45 amDSM - UIO
2 stops17h 35mLATAM Airlines
Tue 4/2911:20 pmUIO - DSM
1 stop14h 06mLATAM Airlines
Deal found 1/20$543
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:54 amDSM - CTG
1 stop7h 16mAmerican Airlines
Wed 11/192:55 pmCTG - DSM
1 stop9h 50mAmerican Airlines
Deal found 1/20$546
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/235:45 amDSM - UIO
2 stops13h 20mDelta
Tue 4/2911:20 pmUIO - DSM
2 stops21h 56mDelta
Deal found 1/21$547
This United deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/233:34 pmDSM - UIO
2 stops31h 51mUnited Airlines
Mon 4/2812:35 amUIO - DSM
2 stops21h 17mUnited Airlines
Deal found 1/21$562
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/193:40 pmDSM - CTG
2 stops32h 31mMultiple Airlines
Wed 2/262:21 pmCTG - DSM
1 stop9h 54mMultiple Airlines
Deal found 1/20$603
This Avianca deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/158:00 amDSM - LIM
2 stops16h 35mMultiple Airlines
Mon 4/282:50 amLIM - DSM
2 stops19h 02mMultiple Airlines
Deal found 1/21$605
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:30 pmDSM - CTG
1 stop18h 16mDelta
Tue 11/184:46 amCTG - DSM
2 stops13h 52mDelta
Deal found 1/20$612
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/115:34 amDSM - LIM
1 stop14h 21mDelta
Tue 2/1811:55 pmLIM - DSM
1 stop11h 45mDelta
Deal found 1/21$646
This LATAM Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/115:34 amDSM - LIM
2 stops25h 41mLATAM Airlines
Tue 2/181:30 pmLIM - DSM
2 stops22h 10mLATAM Airlines
Deal found 1/21$650
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/207:25 amDSM - UIO
2 stops16h 24mAmerican Airlines
Wed 2/2612:35 amUIO - DSM
2 stops12h 46mAmerican Airlines
Deal found 1/21$660
This LATAM Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/195:34 amDSM - CTG
2 stops16h 57mLATAM Airlines
Tue 2/254:46 amCTG - DSM
2 stops13h 50mLATAM Airlines
Deal found 1/20$710
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/28:00 amDSM - GYE
1 stop15h 17mMultiple Airlines
Tue 2/114:15 amGYE - DSM
2 stops20h 03mMultiple Airlines
Deal found 1/20$723

Find flights from Des Moines to South America within your budget

Customize your flight search to find flights from Des Moines to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

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Fly to

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Route

Depart

Return

Price

Des MoinesCartagena

DSM - CTG

DSMCTG

Des Moines

Mon 4/7

7:30 am-12:07 pm

1 stop28h 37m

Cartagena Rafael Nunez

Fri 4/25

1:14 pm-10:55 pm

1 stop9h 41m

$378

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

Wed 4/23

5:45 am-11:20 pm

2 stops17h 35m

Quito Mariscal Sucr

Tue 4/29

11:20 pm-1:26 pm

1 stop14h 06m

$543

Des MoinesCartagena

DSM - CTG

DSMCTG

Des Moines

Mon 4/7

5:45 am-1:11 pm

1 stop7h 26m

Cartagena Rafael Nunez

Thu 4/24

2:05 pm-10:24 pm

1 stop8h 19m

$546

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

Wed 4/23

5:45 am-7:05 pm

2 stops13h 20m

Quito Mariscal Sucr

Tue 4/29

11:20 pm-9:16 pm

2 stops21h 56m

$547

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

Wed 4/23

3:34 pm-11:25 pm

2 stops31h 51m

Quito Mariscal Sucr

Mon 4/28

12:35 am-9:52 pm

2 stops21h 17m

$562

Des MoinesCartagena

DSM - CTG

DSMCTG

Des Moines

Fri 4/4

5:45 am-1:11 pm

1 stop7h 26m

Cartagena Rafael Nunez

Sat 4/26

2:05 pm-10:24 pm

1 stop8h 19m

$566

Des MoinesCartagena

DSM - CTG

DSMCTG

Des Moines

Wed 2/19

6:00 am-8:55 pm

2 stops13h 55m

Cartagena Rafael Nunez

Wed 2/26

4:15 pm-12:25 pm

2 stops21h 10m

$598

Des MoinesLima

DSM - LIM

DSMLIM

Des Moines

Tue 4/15

8:00 am-12:35 am

2 stops16h 35m

Lima J Chavez Intl

Mon 4/28

2:50 am-9:52 pm

2 stops19h 02m

$605

Des MoinesCartagena

DSM - CTG

DSMCTG

Des Moines

Thu 4/3

8:00 am-8:41 am

2 stops24h 41m

Cartagena Rafael Nunez

Wed 4/23

9:38 am-10:45 pm

2 stops37h 07m

$605

Des MoinesLima

DSM - LIM

DSMLIM

Des Moines

Tue 2/11

5:34 am-8:55 pm

1 stop14h 21m

Lima J Chavez Intl

Tue 2/18

11:55 pm-10:40 am

1 stop11h 45m

$646

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 36 results
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Best time to book a flight from Des Moines to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines to South America

Get recent, data-driven insights about flights from Des Moines to South America including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Des Moines to South America?

Currently, May is the cheapest month in which you can book a flight from Des Moines to South America (average of $359). Flying from Des Moines to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to SA?

Find hourly flight availability from Des Moines to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated January 21, 2025.
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Food

7.3

Crew

8.6

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,521 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Food

7.3

Crew

8.6

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines
7.5
Good
1,858 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Food

7.3

Crew

8.6

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
8,984 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Food

7.3

Crew

8.6

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Food

7.3

Crew

8.6

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Air Canada
7.0
Good
8,633 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Food

7.3

Crew

8.6

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to South America?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to South America.

  • What are the cheapest airlines to fly from Des Moines to South America one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $545. Users have also found prices from $579 and $581 on United Airlines and LATAM Airlines, respectively.

  • What are the most popular routes from Des Moines to South America?

    The most popular flight routes from Des Moines to South America are Des Moines - Lima J Chavez Intl, Des Moines - Cartagena Rafael Nunez and Des Moines - Quito Mariscal Sucr.

  • Can I find deals for flights from Des Moines to South America that include hotel bookings?

    Yes. In addition to deals on Des Moines to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to South America.

  • Can I find deals for business class flights from Des Moines to South America?

    Yes. Cheapflights offers flight deals from Des Moines to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to South America?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to South America (average of $359). Flying from Des Moines to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 4 airlines flying from Des Moines to South America

Discover the top 4 airlines that operate flights from Des Moines to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$457Average$802FlexibilityNo cancel feeOn-time71%
DeltaCheapest$508Average$928FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$631Average$1,130FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$757Average$1,198FlexibilityNo cancel feeOn-time69%
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