What are the cheapest airlines to fly from Des Moines to South America one-way?

For one-way options, check prices for LATAM Airlines. According to our data, you can fly for as low as $422. Users have also found prices from $439 and $544 on United Airlines and American Airlines, respectively.

What are the most popular routes from Des Moines to South America?

The most popular flight routes from Des Moines to South America are Des Moines - Lima J Chavez Intl, Des Moines - Santiago Arturo Merino Benitez and Des Moines - Buenos Aires Ministro Pistarini.

What is the cheapest month to fly from Des Moines to South America?

Due to multiple factors, expect to potentially pay more when booking in June. For low rates, November can be a great choice for travel to South America. Flights to South America from Des Moines in November are about $1,146 on average during November, but can be found for as low as $923.

What airport do you fly from for flights from Des Moines to South America?

Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to South America.

Can I find deals for flights from Des Moines to South America that include hotel bookings?

Yes. In addition to deals on Des Moines to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to South America.

Can I find deals for business class flights from Des Moines to South America?

Yes. Cheapflights offers flight deals from Des Moines to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$886+ Flights from Des Moines to South America

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Des Moines to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to South America

Round-trip from	$449 (Kiwi.com)
One-way from	$422 (LATAM Airlines)

From Des Moines to South America

Search Deals

One-way flight from Des Moines to South America

Search Deals

Find flight deals from Des Moines to South America

Cheapest flights from Des Moines to South America
Explore the most affordable flight options available from Des Moines to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2024.

Fri 12/275:39 pmDSM - CTG

2 stops20h 36mAmerican Airlines

Mon 12/308:35 amCTG - DSM

2 stops15h 32mAmerican Airlines

Deal found 12/22

$985

Tue 12/245:50 amDSM - LIM

2 stops14h 05mLATAM Airlines

Sat 1/1812:10 pmLIM - DSM

1 stop11h 40mLATAM Airlines

Deal found 12/22

$1,308

Tue 12/246:55 amDSM - LIM

2 stops13h 00mDelta

Sat 1/188:20 amLIM - DSM

2 stops27h 25mDelta

Deal found 12/22

$1,345

Fri 12/274:10 pmDSM - LIM

1 stop30h 45mUnited Airlines

Wed 1/11:50 amLIM - DSM

1 stop13h 51mUnited Airlines

Deal found 12/22

$1,780

Tue 12/246:45 amDSM - LIM

1 stop15h 40mAmerican Airlines

Fri 1/1712:45 amLIM - DSM

1 stop22h 44mAmerican Airlines

Deal found 12/22

$1,784

Best flights from Des Moines to South America
Discover carefully curated flight deals from Des Moines to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 23, 2024.

Thu 2/68:00 amDSM - CTG

1 stop28h 08mMultiple Airlines

Thu 2/132:21 pmCTG - DSM

1 stop25h 17mMultiple Airlines

Deal found 12/23

$449

Wed 2/55:30 amDSM - CTG

2 stops14h 25mAmerican Airlines

Wed 2/122:30 pmCTG - DSM

1 stop8h 59mAmerican Airlines

Deal found 12/22

$590

Thu 2/68:00 amDSM - UIO

1 stop15h 30mUnited Airlines

Wed 2/121:35 amUIO - DSM

1 stop21h 55mUnited Airlines

Deal found 12/22

$590

Thu 2/65:34 amDSM - UIO

1 stop13h 26mDelta

Thu 2/1311:59 pmUIO - DSM

1 stop18h 37mDelta

Deal found 12/22

$641

Thu 2/67:00 amDSM - UIO

3 stops15h 24mLATAM Airlines

Thu 2/1311:59 pmUIO - DSM

2 stops12h 32mLATAM Airlines

Deal found 12/22

$664

Thu 2/68:00 amDSM - LIM

1 stop14h 55mLufthansa

Wed 2/121:50 amLIM - DSM

1 stop13h 21mLufthansa

Deal found 12/22

$825

Wed 2/53:05 pmDSM - FOR

2 stops22h 25mGOL

Wed 2/1212:45 pmFOR - DSM

2 stops24h 48mGOL

Deal found 12/22

$875

Wed 2/58:00 amDSM - SCL

2 stops25h 10mAir Canada

Wed 2/128:50 pmSCL - DSM

2 stops40h 43mAir Canada

Deal found 12/22

$901

Wed 2/53:05 pmDSM - SCL

1 stop14h 45mCopa Airlines

Tue 2/113:28 amSCL - DSM

2 stops22h 02mCopa Airlines

Deal found 12/22

$1,138

Wed 2/58:00 amDSM - LIM

1 stop14h 55mUnited Airlines

Tue 2/111:50 amLIM - DSM

1 stop13h 25mUnited Airlines

Deal found 12/22

$644

Wed 2/55:55 amDSM - LIM

2 stops14h 35mAmerican Airlines

Wed 2/127:00 amLIM - DSM

2 stops16h 08mAmerican Airlines

Deal found 12/22

$653

Wed 2/55:34 amDSM - CTG

1 stop7h 41mDelta

Tue 2/114:46 amCTG - DSM

2 stops13h 50mDelta

Deal found 12/22

$693

Last-minute flights from Des Moines to South America
Discover last-minute flight deals from Des Moines to South America. Data last updated December 23, 2024 and is based on user searches.

Fri 12/275:39 pmDSM - CTG

2 stops20h 36mAmerican Airlines

Mon 12/302:30 pmCTG - DSM

1 stop9h 56mAmerican Airlines

Deal found 12/22

$985

Wed 1/11:15 pmDSM - SCL

2 stops21h 50mLATAM Airlines

Sat 1/1111:00 amSCL - DSM

1 stop33h 36mLATAM Airlines

Deal found 12/22

$1,246

Wed 1/11:15 pmDSM - SCL

1 stop15h 05mDelta

Sat 1/1111:00 amSCL - DSM

1 stop14h 50mDelta

Deal found 12/23

$1,603

Wed 1/18:00 amDSM - SCL

2 stops27h 20mAvianca

Fri 1/1012:45 amSCL - DSM

2 stops24h 07mAvianca

Deal found 12/22

$4,340

Sat 1/48:00 amDSM - GRU

1 stop20h 15mUnited Airlines

Sun 1/1910:15 pmGRU - DSM

2 stops22h 39mUnited Airlines

Deal found 12/22

$1,181

Sat 1/410:48 amDSM - GRU

2 stops39h 12mLATAM Airlines

Sun 1/1911:10 pmGRU - DSM

2 stops38h 35mLATAM Airlines

Deal found 12/22

$1,217

Tue 1/75:33 amDSM - SCL

2 stops22h 27mLATAM Airlines

Thu 1/236:00 pmSCL - DSM

2 stops19h 45mLATAM Airlines

Deal found 12/22

$847

Tue 1/78:00 amDSM - SCL

1 stop21h 50mUnited Airlines

Thu 1/2310:45 pmSCL - DSM

2 stops26h 07mUnited Airlines

Deal found 12/22

$877

Tue 1/710:32 amDSM - SCL

3 stops24h 48mMultiple Airlines

Thu 1/232:55 pmSCL - DSM

3 stops34h 07mMultiple Airlines

Deal found 12/22

$1,353

Sun 1/126:45 pmDSM - EZE

2 stops33h 35mUnited Airlines

Thu 1/2311:55 pmEZE - DSM

2 stops24h 57mUnited Airlines

Deal found 12/22

$1,383

Fri 1/175:30 amDSM - LIM

2 stops16h 55mAmerican Airlines

Fri 1/247:00 amLIM - DSM

2 stops17h 01mAmerican Airlines

Deal found 12/22

$689

Fri 1/176:45 pmDSM - LIM

2 stops52h 10mUnited Airlines

Thu 1/231:50 amLIM - DSM

2 stops33h 48mUnited Airlines

Deal found 12/22

$780

One-way flights from Des Moines to South America
Search for one-way flight options from Des Moines to South America. Find affordable one-way fares based on user searches. Data last updated December 23, 2024.

Sun 3/306:30 pmDSM - LIM

2 stops11h 55mLATAM Airlines

Deal found 12/22

$422

Sun 3/307:30 amDSM - LIM

3 stops21h 30mMultiple Airlines

Deal found 12/22

$435

Sun 3/303:12 pmDSM - LIM

1 stop31h 48mUnited Airlines

Deal found 12/22

$439

Wed 2/56:46 amDSM - FOR

2 stops30h 44mAmerican Airlines

Deal found 12/22

$544

Mon 1/68:00 amDSM - SCL

2 stops21h 50mUnited Airlines

Deal found 12/23

$592

Thu 12/265:50 amDSM - CNF

2 stops24h 20mDelta

Deal found 12/22

$592

Sun 1/512:47 pmDSM - SCL

1 stop16h 03mAmerican Airlines

Deal found 12/23

$632

Mon 1/611:30 amDSM - FOR

2 stops20h 55mDelta

Deal found 12/22

$657

Fri 1/35:44 amDSM - SCL

3 stops38h 06mLATAM Airlines

Deal found 12/22

$678

Thu 12/266:26 amDSM - CNF

3 stops23h 49mAmerican Airlines

Deal found 12/22

$860

Find flights from Des Moines to South America within your budget

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesCartagena

DSM - CTG

DSMCTG

Des Moines

Thu 2/6

8:00 am-1:08 pm

1 stop28h 08m

Cartagena Rafael Nunez

Thu 2/13

2:21 pm-2:38 pm

1 stop25h 17m

$449

Des MoinesCartagena

DSM - CTG

DSMCTG

Des Moines

Wed 2/5

5:30 am-8:55 pm

2 stops14h 25m

Cartagena Rafael Nunez

Wed 2/12

2:30 pm-10:29 pm

1 stop8h 59m

$590

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

Thu 2/6

8:00 am-12:30 am

1 stop15h 30m

Quito Mariscal Sucr

Wed 2/12

1:35 am-10:30 pm

1 stop21h 55m

$590

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

Thu 2/6

5:34 am-8:00 pm

1 stop13h 26m

Quito Mariscal Sucr

Thu 2/13

11:59 pm-5:36 pm

1 stop18h 37m

$641

Des MoinesLima

DSM - LIM

DSMLIM

Des Moines

Wed 2/5

8:00 am-11:55 pm

1 stop14h 55m

Lima J Chavez Intl

Tue 2/11

1:50 am-2:15 pm

1 stop13h 25m

$644

Des MoinesLima

DSM - LIM

DSMLIM

Des Moines

Wed 2/5

5:55 am-9:30 pm

2 stops14h 35m

Lima J Chavez Intl

Wed 2/12

7:00 am-10:08 pm

2 stops16h 08m

$653

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

Thu 2/6

7:00 am-11:24 pm

3 stops15h 24m

Quito Mariscal Sucr

Thu 2/13

11:59 pm-11:31 am

2 stops12h 32m

$664

Des MoinesCartagena

DSM - CTG

DSMCTG

Des Moines

Wed 2/5

5:34 am-2:15 pm

1 stop7h 41m

Cartagena Rafael Nunez

Tue 2/11

4:46 am-5:36 pm

2 stops13h 50m

$693

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

Thu 2/6

8:00 am-8:50 am

2 stops23h 50m

Quito Mariscal Sucr

Thu 2/13

7:13 pm-11:31 pm

3 stops29h 18m

$701

Des MoinesLima

DSM - LIM

DSMLIM

Des Moines

Tue 2/11

6:26 pm-8:55 pm

1 stop25h 29m

Lima J Chavez Intl

Tue 2/18

11:55 pm-5:36 pm

1 stop18h 41m

$706

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Showing 1-10 of 38 results

Best time to book a flight from Des Moines to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines to South America

Get recent, data-driven insights about flights from Des Moines to South America including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Des Moines to South America?

Currently, May is the cheapest month in which you can book a flight from Des Moines to South America (average of $359). Flying from Des Moines to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to SA?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to South America as you normally would.

Rainfall in South America by month

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Delta

8.0

Very good

8,588 reviews

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

8,588 reviews

Delta

8.0

Very good

8,588 reviews

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines

7.7

Good

1,712 reviews

Delta

8.0

Very good

8,588 reviews

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines

7.5

Good

1,865 reviews

Delta

8.0

Very good

8,588 reviews

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Qantas Airways

7.5

Good

809 reviews

Delta

8.0

Very good

8,588 reviews

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

9,022 reviews

Delta

8.0

Very good

8,588 reviews

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What airport do you fly from for flights from Des Moines to South America?
Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to South America.
What are the cheapest airlines to fly from Des Moines to South America one-way?
For one-way options, check prices for LATAM Airlines. According to our data, you can fly for as low as $422. Users have also found prices from $439 and $544 on United Airlines and American Airlines, respectively.
What are the most popular routes from Des Moines to South America?
The most popular flight routes from Des Moines to South America are Des Moines - Lima J Chavez Intl, Des Moines - Santiago Arturo Merino Benitez and Des Moines - Buenos Aires Ministro Pistarini.
Can I find deals for flights from Des Moines to South America that include hotel bookings?
Yes. In addition to deals on Des Moines to South America flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to South America.
Can I find deals for business class flights from Des Moines to South America?
Yes. Cheapflights offers flight deals from Des Moines to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to South America?
Currently, May is the cheapest month in which you can book a flight from Des Moines to South America (average of $359). Flying from Des Moines to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Des Moines to South America

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$444	Average$839	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$508	Average$903	FlexibilityNo cancel fee	On-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$422+ Cheap flights from Des Moines (DSM) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/30. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to South America with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Des Moines to South America

Round-trip from

One-way from

Find flight deals from Des Moines to South America

Cheapest flights from Des Moines to South AmericaExplore the most affordable flight options available from Des Moines to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2024.

Explore the most affordable flight options available from Des Moines to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2024.

Find flights from Des Moines to South America within your budget

Best time to book a flight from Des Moines to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Des Moines with our price prediction graph.

Travel insights for flights from Des Moines to South America

Get recent, data-driven insights about flights from Des Moines to South America including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Des Moines to South America?

What is the cheapest time of day to fly from DSM to SA?

Find hourly flight availability from Des Moines to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 23, 2024.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

Reviews of airlines servicing South America

Related info for your journey

Find useful and relevant information for your journey from Des Moines to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Des Moines to South America?

What are the cheapest airlines to fly from Des Moines to South America one-way?

What are the most popular routes from Des Moines to South America?

Can I find deals for flights from Des Moines to South America that include hotel bookings?

How can I find direct flights from Des Moines to South America?

Can I find deals for business class flights from Des Moines to South America?

What is the cheapest month to book a flight from Des Moines to South America?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Des Moines to South America

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Des Moines to South America
Explore the most affordable flight options available from Des Moines to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2024.