HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South America

$152+ Cheap flights from Denver (DEN) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — BOG
Mar 31 — Apr 71
Mon 3/31
Mon 4/7
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Denver to South America with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Denver to South America

Keep the following information in mind while searching for Denver to South America flight deals. Data was last updated March 26, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$334
(KAYAK)

One-way from

$152
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$1,050
Provider with most accurate pricing for Denver Intl-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Sao Paulo (SAO) flights.
Search Deals
From Denver Intl to South America
Search Deals
One-way flight from Denver Intl to South America
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($157 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($38 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2025
Search Deals

Find flight deals from Denver to South America

Cheapest flights from Denver to South America
Explore the most affordable flight options available from Denver to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2025.

This KAYAK deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/510:25 pmDEN - CTG
1 stop14h 41mCopa Airlines
Thu 5/86:20 amCTG - DEN
1 stop12h 57mCopa Airlines
Deal found 3/25$334
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/215:30 amDEN - BOG
1 stop12h 50mUnited Airlines
Mon 10/271:30 amBOG - DEN
1 stop11h 05mUnited Airlines
Deal found 3/25$343
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2610:45 amDEN - BOG
2 stops23h 10mDelta
Sat 11/12:48 pmBOG - DEN
1 stop9h 59mDelta
Deal found 3/25$347
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2611:56 pmDEN - CTG
1 stop13h 19mAmerican Airlines
Wed 4/301:35 pmCTG - DEN
2 stops23h 18mAmerican Airlines
Deal found 3/25$350
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/307:20 amDEN - BOG
2 stops12h 57mAmerican Airlines
Thu 5/812:25 amBOG - DEN
1 stop22h 31mAmerican Airlines
Deal found 3/25$354
This LATAM Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/254:00 pmDEN - BOG
2 stops27h 20mLATAM Airlines
Tue 4/12:55 pmBOG - DEN
1 stop21h 20mLATAM Airlines
Deal found 3/24$355
This Copa Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2710:20 pmDEN - BOG
1 stop18h 06mCopa Airlines
Wed 9/34:59 amBOG - DEN
1 stop14h 08mCopa Airlines
Deal found 3/25$371
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2912:55 amDEN - CTG
1 stop11h 16mDelta
Thu 4/179:15 amCTG - DEN
2 stops25h 10mDelta
Deal found 3/26$389
This LATAM Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2912:55 amDEN - CTG
1 stop11h 16mLATAM Airlines
Tue 4/222:34 pmCTG - DEN
1 stop10h 06mLATAM Airlines
Deal found 3/25$411
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/317:45 amDEN - CTG
2 stops23h 56mUnited Airlines
Fri 4/189:38 amCTG - DEN
2 stops15h 06mUnited Airlines
Deal found 3/26$428
This KAYAK deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2410:25 pmDEN - MDE
1 stop17h 36mCopa Airlines
Thu 5/19:42 amMDE - DEN
1 stop9h 35mCopa Airlines
Deal found 3/26$441
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/611:56 pmDEN - MDE
1 stop11h 59mAmerican Airlines
Thu 4/241:55 pmMDE - DEN
1 stop9h 56mAmerican Airlines
Deal found 3/25$453

Cheapflights Fare Finder

Customize your flight search to find flights from Denver to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2025.
Use the filters below to find and compare flights from Denver to South America that are best for you.

Fly from

Denver

Fly to

South America

Route

Depart

Return

Price

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Mon 5/5

10:25 pm-2:06 pm

1 stop14h 41m

Cartagena Rafael Nunez

Thu 5/8

6:20 am-6:17 pm

1 stop12h 57m

$334

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Sun 4/27

12:55 am-7:15 pm

1 stop17h 20m

Bogotá El Dorado

Fri 5/2

2:55 pm-9:25 am

1 stop19h 30m

$343

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Sat 4/26

11:56 pm-2:15 pm

1 stop13h 19m

Cartagena Rafael Nunez

Wed 4/30

1:35 pm-11:53 am

2 stops23h 18m

$350

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Tue 5/6

7:46 am-10:00 pm

1 stop13h 14m

Bogotá El Dorado

Sun 5/11

12:14 am-11:58 pm

1 stop24h 44m

$350

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Wed 4/30

7:20 am-9:17 pm

2 stops12h 57m

Bogotá El Dorado

Thu 5/8

12:25 am-9:56 pm

1 stop22h 31m

$354

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Wed 4/23

4:00 pm-4:15 pm

2 stops23h 15m

Bogotá El Dorado

Sat 4/26

7:00 am-9:25 am

2 stops27h 25m

$358

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Mon 4/28

12:55 am-1:19 pm

1 stop11h 24m

Cartagena Rafael Nunez

Wed 5/21

6:31 am-8:35 am

2 stops27h 04m

$404

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Wed 4/23

10:25 pm-1:29 pm

1 stop14h 04m

Bogotá El Dorado

Sat 4/26

8:35 am-6:17 pm

1 stop10h 42m

$409

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Wed 4/9

7:45 am-8:41 am

2 stops23h 56m

Cartagena Rafael Nunez

Wed 4/16

9:38 am-11:44 pm

2 stops15h 06m

$428

DenverMedellín

DEN - MDE

DENMDE

Denver Intl

Thu 4/24

10:25 pm-5:01 pm

1 stop17h 36m

Medellín Jose Maria Cordova Intl

Thu 5/1

9:42 am-6:17 pm

1 stop9h 35m

$441

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/25

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Denver to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to South America

What is the cheapest month to book a flight from Denver to South America?

Currently, May is the cheapest month in which you can book a flight from Denver to South America (average of $359). Flying from Denver to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to SA?

Find hourly flight availability from Denver to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 26, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Denver to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated March 26, 2025.
Azul
8.0
Very good
771 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Azul
8.0
Very good
771 reviews
Azul
8.0
Very good
771 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Delta
8.0
Very good
7,891 reviews
Azul
8.0
Very good
771 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Copa Airlines
7.6
Good
1,393 reviews
Azul
8.0
Very good
771 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
LATAM Airlines
7.5
Good
1,749 reviews
Azul
8.0
Very good
771 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
United Airlines
7.4
Good
8,608 reviews
Azul
8.0
Very good
771 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.1

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

Related info for your journey

Find useful and relevant information for your journey from Denver to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Denver to South America?

    Most people fly from Denver Intl (DEN) if they book a flight from Denver to South America. Denver Intl is conveniently located just 18.5 mi from Denver’s city center.

  • What are the cheapest airlines to fly from Denver to South America one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $152. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from Denver to South America for a low price.

  • What are the most popular routes from Denver to South America?

    The most popular route from Denver to South America is Denver Intl - Lima J Chavez Intl. You may also consider Denver Intl - Cartagena Rafael Nunez or Denver Intl - Bogotá El Dorado.

  • Can I find deals for flights from Denver to South America that include hotel bookings?

    Yes. In addition to deals on Denver to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to South America.

  • Can I find deals for business class flights from Denver to South America?

    Yes. Cheapflights offers flight deals from Denver to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to South America?

    Currently, May is the cheapest month in which you can book a flight from Denver to South America (average of $359). Flying from Denver to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Denver to South America

See prices for flight routes from nearby airports that may be better suited for you.
Denver to Las Vegas flights
Denver to Cancún flights
Denver to Dallas/Fort Worth flights
Denver to Newark flights
Denver to John F Kennedy Intl flights
Denver to Orlando flights
Denver to Seattle flights
Denver to Sky Harbor Intl flights
Denver to Heathrow flights
Denver to LaGuardia flights
Denver to Hobby flights
Denver to San Diego flights
Denver to O'Hare Intl flights
Denver to Dulles Intl flights
Denver to Reagan-National flights
Denver to Honolulu flights
Denver to Miami flights
Denver to Los Angeles flights
Denver to San Francisco flights
Denver to Tampa flights
Denver to Boston flights
Denver to Narita flights
Denver to Nashville flights
Denver to Baltimore flights
Denver to Charleston flights
Denver to New Orleans flights
Denver to Austin flights
Denver to Vancouver Intl flights
Denver to Charlotte flights
Denver to San José del Cabo flights
Denver to Detroit flights
Denver to George Bush Intcntl flights
Denver to Fort Lauderdale flights
Denver to Ontario flights
Denver to Leonardo da Vinci/Fiumicino flights
Denver to Philadelphia flights
Denver to Mexico City flights
Denver to Anchorage flights
Denver to Kahului flights
Denver to Portland flights
Denver to Raleigh flights
Denver to Cozumel flights
Denver to Minneapolis flights
Denver to Atlanta flights
Denver to Lihue flights
Denver to Frankfurt flights
Denver to Puerto Vallarta flights
Denver to Midway flights
Denver to Dublin flights
Denver to Pittsburgh flights

Top 9 airlines flying from Denver to South America

Discover the top 9 airlines that operate flights from Denver to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$251Average$901FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$299Average$781FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$299Average$858FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$323Average$928FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$330Average$673FlexibilityNo cancel feeOn-time70%
AviancaCheapest$413Average$539FlexibilityNo cancel feeOn-time71%
Air CanadaCheapest$798Average$976FlexibilityNo cancel feeOn-time67%
AeromexicoCheapest$803Average$945FlexibilityNo cancel feeOn-timeN/A
GOLCheapest$882Average$1,422FlexibilityNo cancel feeOn-time74%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.