HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South America

$156+ Cheap flights from Denver (DEN) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/4. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — BOG
Apr 20 — Apr 271
Sun 4/20
Sun 4/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Denver to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Denver to South America

Keep the following information in mind while searching for Denver to South America flight deals. Data was last updated April 15, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$334
(Copa Airlines)

One-way from

$156
(Delta)

Popular in

December

Cheapest in

October

Average price

$1,098
Provider with most accurate pricing for Denver Intl-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Sao Paulo (SAO) flights.
Search Deals
From Denver Intl to South America
Search Deals
One-way flight from Denver Intl to South America
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($178 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($40 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals

Find flight deals from Denver to South America

Cheapest flights from Denver to South America
Explore the most affordable flight options available from Denver to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.

This Copa Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/510:42 pmDEN - CTG
1 stop8h 40mCopa Airlines
Thu 6/126:20 amCTG - DEN
1 stop12h 57mCopa Airlines
Deal found 4/14$334
This LATAM Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/297:20 amDEN - BOG
1 stop10h 55mLATAM Airlines
Tue 5/139:00 amBOG - DEN
1 stop9h 39mLATAM Airlines
Deal found 4/14$343
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1011:59 pmDEN - CTG
1 stop13h 11mAmerican Airlines
Thu 9/41:55 pmCTG - DEN
1 stop10h 20mAmerican Airlines
Deal found 4/15$346
This United deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/307:45 amDEN - BOG
1 stop10h 35mUnited Airlines
Tue 5/612:14 amBOG - DEN
1 stop15h 18mUnited Airlines
Deal found 4/14$346
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2912:55 amDEN - BOG
2 stops14h 20mDelta
Wed 5/77:00 amBOG - DEN
2 stops18h 12mDelta
Deal found 4/14$347
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1212:06 pmDEN - CTG
1 stop24h 13mDelta
Thu 5/152:34 pmCTG - DEN
1 stop10h 42mDelta
Deal found 4/14$351
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/169:06 amDEN - BOG
1 stop12h 24mAmerican Airlines
Tue 4/222:10 pmBOG - DEN
1 stop22h 08mAmerican Airlines
Deal found 4/15$352
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1010:25 pmDEN - BOG
1 stop10h 04mCopa Airlines
Sat 5/179:45 amBOG - DEN
1 stop9h 32mCopa Airlines
Deal found 4/14$364
This KAYAK deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/512:59 amDEN - CTG
1 stop10h 53mLATAM Airlines
Sat 9/132:06 pmCTG - DEN
1 stop10h 41mLATAM Airlines
Deal found 4/15$406
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/178:29 pmDEN - CTG
2 stops35h 12mUnited Airlines
Fri 5/99:38 amCTG - DEN
2 stops24h 22mUnited Airlines
Deal found 4/14$408
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1510:25 pmDEN - MDE
1 stop8h 53mCopa Airlines
Mon 5/199:15 amMDE - DEN
1 stop10h 02mCopa Airlines
Deal found 4/13$440
This Copa Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1410:25 pmDEN - UIO
1 stop18h 05mCopa Airlines
Wed 5/215:59 amUIO - DEN
1 stop13h 18mCopa Airlines
Deal found 4/14$450

Cheapflights Fare Finder

Customize your flight search to find flights from Denver to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2025.
Use the filters below to find and compare flights from Denver to South America that are best for you.

Fly from

Denver

Fly to

South America

Route

Depart

Return

Price

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Thu 6/5

10:42 pm-8:22 am

1 stop8h 40m

Cartagena Rafael Nunez

Thu 6/12

6:20 am-6:17 pm

1 stop12h 57m

$334

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Tue 4/29

7:20 am-7:15 pm

1 stop10h 55m

Bogotá El Dorado

Fri 5/16

9:00 am-12:16 am

1 stop16h 16m

$343

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Sun 8/10

11:59 pm-2:10 pm

1 stop13h 11m

Cartagena Rafael Nunez

Thu 9/4

1:55 pm-11:15 pm

1 stop10h 20m

$346

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Wed 4/30

7:45 am-7:20 pm

1 stop10h 35m

Bogotá El Dorado

Tue 5/6

12:14 am-2:32 pm

1 stop15h 18m

$346

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Tue 4/29

12:55 am-4:15 pm

2 stops14h 20m

Bogotá El Dorado

Wed 5/7

7:00 am-12:12 am

2 stops18h 12m

$347

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Mon 5/12

12:06 pm-1:19 pm

1 stop24h 13m

Cartagena Rafael Nunez

Thu 5/15

2:34 pm-12:16 am

1 stop10h 42m

$351

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Thu 5/1

9:05 am-10:30 pm

1 stop12h 25m

Bogotá El Dorado

Mon 5/5

2:10 pm-11:21 am

1 stop22h 11m

$352

DenverBogotá

DEN - BOG

DENBOG

Denver Intl

Sat 5/10

10:25 pm-9:29 am

1 stop10h 04m

Bogotá El Dorado

Sat 5/17

9:45 am-6:17 pm

1 stop9h 32m

$364

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Fri 9/5

12:59 am-12:52 pm

1 stop10h 53m

Cartagena Rafael Nunez

Sat 9/13

2:06 pm-11:47 pm

1 stop10h 41m

$406

DenverCartagena

DEN - CTG

DENCTG

Denver Intl

Wed 5/14

5:16 am-8:43 am

2 stops26h 27m

Cartagena Rafael Nunez

Wed 5/21

9:38 am-11:58 pm

2 stops15h 20m

$408

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/14

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Denver to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to South America

What is the cheapest month to book a flight from Denver to South America?

Currently, May is the cheapest month in which you can book a flight from Denver to South America (average of $359). Flying from Denver to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to SA?

Find hourly flight availability from Denver to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Denver to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 15, 2025.
Azul
8.0
Very good
774 reviews

Comfort

8.0

Food

7.1

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Azul
8.0
Very good
774 reviews
Azul
8.0
Very good
774 reviews

Comfort

8.0

Food

7.1

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Delta
8.0
Very good
7,917 reviews
Azul
8.0
Very good
774 reviews

Comfort

8.0

Food

7.1

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Copa Airlines
7.6
Good
1,408 reviews
Azul
8.0
Very good
774 reviews

Comfort

8.0

Food

7.1

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
LATAM Airlines
7.5
Good
1,758 reviews
Azul
8.0
Very good
774 reviews

Comfort

8.0

Food

7.1

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
United Airlines
7.4
Good
8,658 reviews
Azul
8.0
Very good
774 reviews

Comfort

8.0

Food

7.1

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

Related info for your journey

Find useful and relevant information for your journey from Denver to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Denver to South America?

    Most people fly from Denver Intl (DEN) if they book a flight from Denver to South America. Denver Intl is conveniently located just 18.5 mi from Denver’s city center.

  • What are the cheapest airlines to fly from Denver to South America one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $156. However, be on the lookout for offers from LATAM Airlines and Copa Airlines, as they are both options that can get you from Denver to South America for a low price.

  • What are the most popular routes from Denver to South America?

    The most popular route from Denver to South America is Denver Intl - Medellín Jose Maria Cordova Intl. You may also consider Denver Intl - Bogotá El Dorado or Denver Intl - Lima J Chavez Intl.

  • Can I find deals for flights from Denver to South America that include hotel bookings?

    Yes. In addition to deals on Denver to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to South America.

  • Can I find deals for business class flights from Denver to South America?

    Yes. Cheapflights offers flight deals from Denver to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to South America?

    Currently, May is the cheapest month in which you can book a flight from Denver to South America (average of $359). Flying from Denver to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Denver to South America

See prices for flight routes from nearby airports that may be better suited for you.
Denver to Las Vegas flights
Denver to Newark flights
Denver to John F Kennedy Intl flights
Denver to Dallas/Fort Worth flights
Denver to Seattle flights
Denver to Hobby flights
Denver to O'Hare Intl flights
Denver to Orlando flights
Denver to Cancún flights
Denver to Sky Harbor Intl flights
Denver to LaGuardia flights
Denver to George Bush Intcntl flights
Denver to Heathrow flights
Denver to San Francisco flights
Denver to San Diego flights
Denver to Dulles Intl flights
Denver to Honolulu flights
Denver to Narita flights
Denver to Los Angeles flights
Denver to Nashville flights
Denver to Charlotte flights
Denver to Baltimore flights
Denver to Boston flights
Denver to Miami flights
Denver to Tampa flights
Denver to Philadelphia flights
Denver to Ontario flights
Denver to Vancouver Intl flights
Denver to Reagan-National flights
Denver to Austin flights
Denver to Fort Lauderdale flights
Denver to Anchorage flights
Denver to New Orleans flights
Denver to Kahului flights
Denver to Mexico City flights
Denver to Leonardo da Vinci/Fiumicino flights
Denver to Minneapolis flights
Denver to Raleigh flights
Denver to Charleston flights
Denver to Atlanta flights
Denver to Detroit flights
Denver to Portland flights
Denver to Charles de Gaulle flights
Denver to Santa Ana flights
Denver to Midway flights
Denver to Grand Rapids flights
Denver to Dublin flights
Denver to Lihue flights
Denver to San José del Cabo flights
Denver to Syracuse flights

Top 8 airlines flying from Denver to South America

Discover the top 8 airlines that operate flights from Denver to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$299Average$901FlexibilityNo cancel feeOn-time71%
DeltaCheapest$300Average$985FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$310Average$915FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$327Average$994FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$347Average$705FlexibilityNo cancel feeOn-time70%
AeromexicoCheapest$794Average$1,148FlexibilityNo cancel feeOn-timeN/A
Air CanadaCheapest$798Average$991FlexibilityNo cancel feeOn-time67%
GOLCheapest$823Average$1,233FlexibilityNo cancel feeOn-time74%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.