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South America

$142+ Cheap flights from Midway (MDW) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — BOG
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Midway to South America

Keep the following information in mind while searching for Midway to South America flight deals. Data was last updated April 17, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$310
(LATAM Airlines)

One-way from

$142
(LATAM Airlines)

Popular in

December

Cheapest in

March

Average price

$873
Provider with most accurate pricing for Chicago (CHI)-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Sao Paulo (SAO) flights.
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From Chicago Midway to South America
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One-way flight from Chicago Midway to South America
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Highest demand for flights based on searches. 1% potential increase in price ($20 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Midway to South America

Cheapest flights from Midway to South America
Explore the most affordable flight options available from Midway to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This LATAM Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1410:25 amMDW - BOG
1 stop8h 50mLATAM Airlines
Wed 5/219:00 amBOG - MDW
1 stop12h 27mLATAM Airlines
Deal found 4/17$310
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/136:00 amMDW - BOG
1 stop7h 40mDelta
Tue 5/207:00 amBOG - MDW
2 stops14h 27mDelta
Deal found 4/16$316
This LATAM Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/19:52 amMDW - MDE
2 stops12h 51mLATAM Airlines
Tue 5/610:50 amMDE - MDW
2 stops11h 32mLATAM Airlines
Deal found 4/16$425
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/269:12 pmMDW - MDE
1 stop15h 46mMultiple Airlines
Wed 6/41:53 pmMDE - MDW
1 stop30h 24mMultiple Airlines
Deal found 4/17$436
This LATAM Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/36:04 amMDW - CTG
1 stop7h 08mLATAM Airlines
Thu 5/89:15 amCTG - MDW
2 stops24h 25mLATAM Airlines
Deal found 4/17$454
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/25:59 pmMDW - CTG
2 stops19h 13mDelta
Tue 5/62:34 pmCTG - MDW
1 stop7h 48mDelta
Deal found 4/17$463
This LATAM Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/246:04 amMDW - UIO
2 stops13h 01mLATAM Airlines
Fri 4/257:09 amUIO - MDW
2 stops25h 58mLATAM Airlines
Deal found 4/17$470
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/176:04 amMDW - UIO
2 stops13h 01mDelta
Thu 5/811:20 pmUIO - MDW
2 stops19h 25mDelta
Deal found 4/16$498
This LATAM Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/94:26 pmMDW - LIM
2 stops13h 59mLATAM Airlines
Sun 6/1512:05 amLIM - MDW
2 stops21h 40mLATAM Airlines
Deal found 4/15$509
This Trip.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/16:00 amMDW - BOG
1 stop13h 15mMultiple Airlines
Sun 6/87:00 amBOG - MDW
1 stop13h 17mMultiple Airlines
Deal found 4/17$513
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/29:52 amMDW - MDE
2 stops12h 13mDelta
Thu 5/85:27 amMDE - MDW
2 stops16h 01mDelta
Deal found 4/17$530
This KAYAK deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/276:50 pmMDW - CUZ
2 stops17h 40mLATAM Airlines
Sun 11/94:15 amCUZ - MDW
2 stops18h 29mLATAM Airlines
Deal found 4/16$561

Cheapflights Fare Finder

Customize your flight search to find flights from Midway to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to South America that are best for you.

Fly from

Midway

Fly to

South America

Route

Depart

Return

Price

ChicagoBogotá

MDW - BOG

MDWBOG

Chicago Midway

Wed 5/14

10:25 am-7:15 pm

1 stop8h 50m

Bogotá El Dorado

Wed 5/21

9:00 am-9:27 pm

1 stop12h 27m

$310

ChicagoBogotá

MDW - BOG

MDWBOG

Chicago Midway

Tue 5/13

6:00 am-1:40 pm

1 stop7h 40m

Bogotá El Dorado

Tue 5/20

7:00 am-9:27 pm

2 stops14h 27m

$316

ChicagoMedellín

MDW - MDE

MDWMDE

Chicago Midway

Thu 5/1

9:52 am-10:43 pm

2 stops12h 51m

Medellín Jose Maria Cordova Intl

Tue 5/6

10:50 am-10:22 pm

2 stops11h 32m

$425

ChicagoMedellín

MDW - MDE

MDWMDE

Chicago Midway

Mon 5/26

9:12 pm-12:58 pm

1 stop15h 46m

Medellín Jose Maria Cordova Intl

Wed 6/4

1:53 pm-8:17 pm

1 stop30h 24m

$436

ChicagoCartagena

MDW - CTG

MDWCTG

Chicago Midway

Sat 5/3

6:04 am-1:12 pm

1 stop7h 08m

Cartagena Rafael Nunez

Thu 5/8

9:15 am-9:40 am

2 stops24h 25m

$454

ChicagoCartagena

MDW - CTG

MDWCTG

Chicago Midway

Fri 5/2

5:59 pm-1:12 pm

2 stops19h 13m

Cartagena Rafael Nunez

Tue 5/6

2:34 pm-10:22 pm

1 stop7h 48m

$463

ChicagoQuito

MDW - UIO

MDWUIO

Chicago Midway

Thu 4/24

6:04 am-7:05 pm

2 stops13h 01m

Quito Mariscal Sucr

Fri 4/25

7:09 am-9:07 am

2 stops25h 58m

$470

ChicagoLima

MDW - LIM

MDWLIM

Chicago Midway

Mon 6/9

4:26 pm-6:25 am

2 stops13h 59m

Lima J Chavez Intl

Sun 6/15

12:05 am-9:45 pm

2 stops21h 40m

$509

ChicagoBogotá

MDW - BOG

MDWBOG

Chicago Midway

Sun 6/1

6:00 am-7:15 pm

1 stop13h 15m

Bogotá El Dorado

Sun 6/8

7:00 am-8:17 pm

1 stop13h 17m

$513

ChicagoQuito

MDW - UIO

MDWUIO

Chicago Midway

Mon 5/5

6:45 pm-7:05 pm

2 stops24h 20m

Quito Mariscal Sucr

Wed 5/21

9:11 am-9:27 pm

2 stops12h 16m

$513

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 56 results
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Best time to book a flight from Midway to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to South America

What is the cheapest time of day to fly from MDW to SA?

Find hourly flight availability from Midway to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Chicago Midway Airport to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 17, 2025.
Delta
8.0
Very good
7,917 reviews

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,917 reviews
Delta
8.0
Very good
7,917 reviews

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,761 reviews
Delta
8.0
Very good
7,917 reviews

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Midway to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the most popular routes from Chicago Midway Airport to South America?

    While some choose either Chicago Midway - Medellín Jose Maria Cordova Intl or Chicago Midway - Bogotá El Dorado, Chicago Midway - Lima J Chavez Intl is the most popular route from Chicago Midway Airport to South America.

  • Can I find deals for flights from Midway to South America that include hotel bookings?

    Yes. In addition to deals on Midway to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to South America.

  • Can I find deals for business class flights from Midway to South America?

    Yes. Cheapflights offers flight deals from Midway to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago Midway Airport to South America?

    Currently, May is the cheapest month in which you can book a flight from Chicago Midway Airport to South America (average of $359). Flying from Chicago Midway Airport to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Midway to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Midway to South America

Discover the top 2 airlines that operate flights from Midway to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$467Average$649FlexibilityNo cancel feeOn-time81%
DeltaCheapest$488Average$488FlexibilityNo cancel feeOn-timeN/A

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