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South America

$143+ Cheap flights from Midway (MDW) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/2. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — BOG
abr. 2 — abr. 91
mié. 4/2
mié. 4/9
1 adult, Economy
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Cheap flight deals from Midway to South America

Keep the following information in mind while searching for Midway to South America flight deals. Data was last updated marzo 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$312
(Delta)

One-way from

$143
(Delta)

Popular in

December

Cheapest in

March

Average price

$708
Provider with most accurate pricing for Chicago (CHI)-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Sao Paulo (SAO) flights.
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From Chicago Midway to South America
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One-way flight from Chicago Midway to South America
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Highest demand for flights based on searches. 0% potential increase in price ($8 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Midway to South America

Cheapest flights from Midway to South America
Explore the most affordable flight options available from Midway to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on marzo 28, 2025.

This LATAM Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/26:00 amMDW - BOG
1 stop7h 40mLATAM Airlines
lun. 4/72:55 pmBOG - MDW
1 stop18h 12mLATAM Airlines
Deal found 3/26$312
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/36:04 amMDW - BOG
1 stop13h 11mDelta
sáb. 5/102:55 pmBOG - MDW
2 stops17h 45mDelta
Deal found 3/26$316
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/36:04 amMDW - CTG
1 stop7h 08mLATAM Airlines
sáb. 5/102:34 pmCTG - MDW
1 stop19h 06mLATAM Airlines
Deal found 3/27$368
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/56:04 amMDW - LIM
1 stop15h 06mDelta
lun. 5/2611:20 pmLIM - MDW
1 stop10h 15mDelta
Deal found 3/26$385
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/56:04 amMDW - MDE
2 stops11h 21mDelta
lun. 5/129:13 amMDE - MDW
2 stops26h 40mDelta
Deal found 3/27$407
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/306:25 pmMDW - CTG
2 stops18h 54mDelta
sáb. 6/212:30 pmCTG - MDW
1 stop21h 26mDelta
Deal found 3/27$410
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 4/265:59 pmMDW - UIO
2 stops26h 01mDelta
lun. 4/2811:20 pmUIO - MDW
1 stop9h 47mDelta
Deal found 3/27$431
This Trip.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/96:50 pmMDW - LIM
1 stop10h 10mLATAM Airlines
sáb. 10/2512:15 pmLIM - MDW
1 stop21h 36mLATAM Airlines
Deal found 3/26$448
This eDestinos deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/126:31 pmMDW - UIO
2 stops24h 34mLATAM Airlines
sáb. 5/177:09 pmUIO - MDW
2 stops26h 19mLATAM Airlines
Deal found 3/27$481
This LATAM Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/46:00 amMDW - MDE
2 stops24h 15mLATAM Airlines
mar. 4/87:55 amMDE - MDW
2 stops25h 12mLATAM Airlines
Deal found 3/27$483
This Kissandfly.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/116:00 amMDW - LIM
2 stops14h 15mKLM
dom. 5/181:30 pmLIM - MDW
2 stops20h 10mKLM
Deal found 3/26$501
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/1110:55 amMDW - BOG
1 stop9h 15mMultiple Airlines
dom. 5/184:59 amBOG - MDW
2 stops12h 31mMultiple Airlines
Deal found 3/26$602

Cheapflights Fare Finder

Customize your flight search to find flights from Midway to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 28, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to South America that are best for you.

Fly from

Midway

Fly to

South America

Route

Depart

Return

Price

ChicagoBogotá

MDW - BOG

MDWBOG

Chicago Midway

dom. 4/13

6:00 am-1:40 pm

1 stop7h 40m

Bogotá El Dorado

vie. 4/18

9:00 am-10:22 pm

1 stop13h 22m

$312

ChicagoBogotá

MDW - BOG

MDWBOG

Chicago Midway

sáb. 5/3

9:52 am-7:15 pm

1 stop9h 23m

Bogotá El Dorado

sáb. 5/10

2:55 pm-9:40 am

1 stop18h 45m

$331

ChicagoCartagena

MDW - CTG

MDWCTG

Chicago Midway

sáb. 5/3

6:04 am-1:12 pm

1 stop7h 08m

Cartagena Rafael Nunez

sáb. 5/10

2:34 pm-9:40 am

1 stop19h 06m

$368

ChicagoLima

MDW - LIM

MDWLIM

Chicago Midway

lun. 5/5

6:04 am-9:10 pm

1 stop15h 06m

Lima J Chavez Intl

lun. 5/26

11:20 pm-9:35 am

1 stop10h 15m

$385

ChicagoLima

MDW - LIM

MDWLIM

Chicago Midway

mar. 4/29

6:04 am-10:00 pm

2 stops15h 56m

Lima J Chavez Intl

mar. 5/6

1:30 pm-11:53 am

2 stops22h 23m

$389

ChicagoMedellín

MDW - MDE

MDWMDE

Chicago Midway

lun. 5/5

6:04 am-5:25 pm

2 stops11h 21m

Medellín Jose Maria Cordova Intl

lun. 5/12

9:13 am-11:53 am

2 stops26h 40m

$407

ChicagoCartagena

MDW - CTG

MDWCTG

Chicago Midway

vie. 5/30

6:25 pm-1:19 pm

2 stops18h 54m

Cartagena Rafael Nunez

sáb. 6/21

2:30 pm-11:56 am

1 stop21h 26m

$410

ChicagoQuito

MDW - UIO

MDWUIO

Chicago Midway

sáb. 4/26

5:59 pm-8:00 pm

2 stops26h 01m

Quito Mariscal Sucr

lun. 4/28

11:20 pm-9:07 am

1 stop9h 47m

$431

ChicagoQuito

MDW - UIO

MDWUIO

Chicago Midway

lun. 5/12

6:31 pm-7:05 pm

2 stops24h 34m

Quito Mariscal Sucr

sáb. 5/17

7:09 pm-9:28 pm

2 stops26h 19m

$481

ChicagoMedellín

MDW - MDE

MDWMDE

Chicago Midway

sáb. 4/12

6:00 am-6:14 am

2 stops24h 14m

Medellín Jose Maria Cordova Intl

jue. 4/17

8:03 pm-5:59 pm

2 stops21h 56m

$483

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Showing 1-10 of 53 results
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Best time to book a flight from Midway to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago Midway Airport to South America

What is the cheapest time of day to fly from MDW to SA?

Find hourly flight availability from Midway to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated marzo 28, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Chicago Midway Airport to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated marzo 28, 2025.
Delta
8.0
Very good
7,897 reviews

Entertainment

7.9

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,897 reviews
Delta
8.0
Very good
7,897 reviews

Entertainment

7.9

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
KLM
7.8
Good
1,321 reviews
Delta
8.0
Very good
7,897 reviews

Entertainment

7.9

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,750 reviews
Delta
8.0
Very good
7,897 reviews

Entertainment

7.9

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Volaris
6.7
Okay
1,170 reviews
Delta
8.0
Very good
7,897 reviews

Entertainment

7.9

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Midway to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Chicago Midway Airport to South America one-way?

    The cheapest airlines for a one-way flight from Chicago Midway Airport to South America are Delta ($143), LATAM Airlines ($144), and Volaris ($544).

  • What are the most popular routes from Chicago Midway Airport to South America?

    While some choose either Chicago Midway - Bogotá El Dorado or Chicago Midway - Medellín Jose Maria Cordova Intl, Chicago Midway - Lima J Chavez Intl is the most popular route from Chicago Midway Airport to South America.

  • Can I find deals for flights from Midway to South America that include hotel bookings?

    Yes. In addition to deals on Midway to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to South America.

  • Can I find deals for business class flights from Midway to South America?

    Yes. Cheapflights offers flight deals from Midway to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago Midway Airport to South America?

    Currently, May is the cheapest month in which you can book a flight from Chicago Midway Airport to South America (average of $359). Flying from Chicago Midway Airport to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Midway to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Midway to South America

Discover the top 2 airlines that operate flights from Midway to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$295Average$605FlexibilityNo cancel feeOn-time81%
DeltaCheapest$488Average$488FlexibilityNo cancel feeOn-timeN/A
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