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South America

$168+ Cheap flights from Midway (MDW) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
MDW — BOG
ene. 26 — feb. 21
dom. 1/26
dom. 2/2
1 adult, Economy
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Cheap flight deals from Midway to South America

Discover tips and strategies to find the most affordable flight options for your journey from Midway (MDW) to South America (0SA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated enero 21, 2025.

Round-trip from

$312
(CheapOair)

One-way from

$173
(Delta)
From Chicago Midway to South America
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One-way flight from Chicago Midway to South America
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Find flight deals from Midway to South America

Cheapest flights from Midway to South America
Explore the most affordable flight options available from Midway to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 21, 2025.

This CheapOair deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/26:00 amMDW - BOG
1 stop13h 33mLATAM Airlines
lun. 4/72:55 pmBOG - MDW
1 stop18h 12mLATAM Airlines
Deal found 1/21$312
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 3/166:00 amMDW - BOG
1 stop13h 30mDelta
vie. 3/213:50 pmBOG - MDW
1 stop17h 19mDelta
Deal found 1/21$313
This LATAM Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 3/26:00 amMDW - CTG
1 stop7h 15mLATAM Airlines
mié. 3/122:26 pmCTG - MDW
1 stop8h 01mLATAM Airlines
Deal found 1/19$366
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/36:00 amMDW - CTG
1 stop7h 15mDelta
sáb. 2/153:30 pmCTG - MDW
1 stop7h 50mDelta
Deal found 1/21$367
This LATAM Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/410:57 amMDW - MDE
2 stops19h 50mLATAM Airlines
mié. 3/129:48 amMDE - MDW
2 stops23h 21mLATAM Airlines
Deal found 1/20$383
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 1/2910:57 amMDW - UIO
1 stop8h 03mDelta
lun. 2/1011:59 pmUIO - MDW
1 stop13h 00mDelta
Deal found 1/20$424
This LATAM Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/13:41 pmMDW - UIO
2 stops26h 21mLATAM Airlines
mar. 3/187:13 amUIO - MDW
2 stops25h 56mLATAM Airlines
Deal found 1/21$442
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/66:00 amMDW - MDE
2 stops15h 14mDelta
mar. 3/185:33 amMDE - MDW
2 stops16h 50mDelta
Deal found 1/20$451
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/1712:43 pmMDW - MDE
1 stop24h 16mMultiple Airlines
lun. 2/242:54 pmMDE - MDW
1 stop25h 18mMultiple Airlines
Deal found 1/20$494
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/196:00 amMDW - CTG
1 stop7h 15mMultiple Airlines
mié. 2/266:39 amCTG - MDW
2 stops12h 44mMultiple Airlines
Deal found 1/20$511
This Kissandfly.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/66:00 amMDW - CTG
1 stop7h 15mKLM
jue. 3/132:26 pmCTG - MDW
2 stops22h 10mKLM
Deal found 1/19$515
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/108:00 amMDW - LIM
1 stop30h 35mMultiple Airlines
lun. 4/141:15 amLIM - MDW
2 stops18h 30mMultiple Airlines
Deal found 1/21$519

Find flights from Midway to South America within your budget

Customize your flight search to find flights from Midway to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 21, 2025.

Fly from

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Fly to

Any airport

Route

Depart

Return

Price

ChicagoBogotá

MDW - BOG

MDWBOG

Chicago Midway

mié. 4/2

6:00 am-7:33 pm

1 stop13h 33m

Bogotá El Dorado

lun. 4/7

2:55 pm-9:07 am

1 stop18h 12m

$312

ChicagoBogotá

MDW - BOG

MDWBOG

Chicago Midway

jue. 3/6

6:00 am-2:25 pm

1 stop7h 25m

Bogotá El Dorado

mar. 3/11

3:50 pm-9:09 am

1 stop17h 19m

$313

ChicagoCartagena

MDW - CTG

MDWCTG

Chicago Midway

lun. 2/3

6:00 am-2:15 pm

1 stop7h 15m

Cartagena Rafael Nunez

vie. 2/7

3:30 pm-10:20 pm

1 stop7h 50m

$367

ChicagoMedellín

MDW - MDE

MDWMDE

Chicago Midway

mar. 3/4

10:57 am-7:47 am

2 stops19h 50m

Medellín Jose Maria Cordova Intl

mié. 3/12

9:48 am-9:09 am

2 stops23h 21m

$383

ChicagoCartagena

MDW - CTG

MDWCTG

Chicago Midway

dom. 2/2

5:07 pm-2:15 pm

1 stop20h 08m

Cartagena Rafael Nunez

mié. 2/5

3:30 pm-10:20 pm

1 stop7h 50m

$417

ChicagoQuito

MDW - UIO

MDWUIO

Chicago Midway

lun. 2/3

10:57 am-8:00 pm

1 stop8h 03m

Quito Mariscal Sucr

lun. 2/10

11:59 pm-4:20 pm

1 stop17h 21m

$424

ChicagoMedellín

MDW - MDE

MDWMDE

Chicago Midway

jue. 3/6

6:00 am-10:14 pm

2 stops15h 14m

Medellín Jose Maria Cordova Intl

mar. 3/18

5:33 am-10:23 pm

2 stops16h 50m

$451

ChicagoQuito

MDW - UIO

MDWUIO

Chicago Midway

mar. 2/4

10:57 am-8:00 pm

1 stop8h 03m

Quito Mariscal Sucr

mié. 2/5

11:59 pm-10:12 am

1 stop11h 13m

$467

ChicagoMedellín

MDW - MDE

MDWMDE

Chicago Midway

lun. 2/17

12:43 pm-1:59 pm

1 stop24h 16m

Medellín Jose Maria Cordova Intl

lun. 2/24

2:54 pm-3:12 pm

1 stop25h 18m

$494

ChicagoLima

MDW - LIM

MDWLIM

Chicago Midway

jue. 4/10

8:00 am-2:35 pm

1 stop30h 35m

Lima J Chavez Intl

lun. 4/14

1:15 am-7:45 pm

2 stops18h 30m

$519

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 59 results
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Best time to book a flight from Midway to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Midway with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Midway to South America

Get recent, data-driven insights about flights from Midway to South America including ideal travel times, pricing trends, and more.

What is the cheapest time of day to fly from MDW to SA?

Find hourly flight availability from Midway to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated enero 21, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Chicago Midway Airport to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated enero 21, 2025.
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.6

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,521 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.6

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

KLM
7.8
Good
1,341 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.6

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines
7.5
Good
1,858 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.6

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Aeromexico
7.5
Good
1,849 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.6

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Volaris
6.7
Okay
1,249 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.6

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Midway to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Chicago Midway Airport to South America one-way?

    The cheapest airlines for a one-way flight from Chicago Midway Airport to South America are Delta ($173), LATAM Airlines ($178), and Volaris ($426).

  • What are the most popular routes from Chicago Midway Airport to South America?

    While some choose either Chicago Midway - Bogotá El Dorado or Chicago Midway - Cartagena Rafael Nunez, Chicago Midway - Lima J Chavez Intl is the most popular route from Chicago Midway Airport to South America.

  • Can I find deals for flights from Midway to South America that include hotel bookings?

    Yes. In addition to deals on Midway to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Midway to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Midway to South America.

  • Can I find deals for business class flights from Midway to South America?

    Yes. Cheapflights offers flight deals from Midway to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago Midway Airport to South America?

    Currently, May is the cheapest month in which you can book a flight from Chicago Midway Airport to South America (average of $359). Flying from Chicago Midway Airport to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Midway to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Midway to South America

Discover the top 2 airlines that operate flights from Midway to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$295Average$605FlexibilityNo cancel feeOn-time81%
DeltaCheapest$488Average$488FlexibilityNo cancel feeOn-timeN/A
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