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South America

$258+ Cheap flights from Charleston (CHS) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BOG
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Cheap flight deals from Charleston to South America

Keep the following information in mind while searching for Charleston to South America flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$268
(Mytrip)

One-way from

$258
(Mytrip)
Provider with most accurate pricing for Charleston-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Charleston-Sao Paulo (SAO) flights.
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From Charleston to South America
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One-way flight from Charleston to South America
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Find flight deals from Charleston to South America

Cheapest flights from Charleston to South America
Explore the most affordable flight options available from Charleston to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This Mytrip deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/37:15 pmCHS - CTG
1 stop17h 52mSpirit Airlines
Sat 5/101:15 pmCTG - CHS
1 stop18h 23mSpirit Airlines
Deal found 3/27$268
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/94:30 pmCHS - CTG
2 stops20h 40mMultiple Airlines
Fri 5/161:15 pmCTG - CHS
1 stop18h 23mMultiple Airlines
Deal found 3/27$349
This Mytrip deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/410:25 amCHS - MDE
1 stop27h 50mSpirit Airlines
Fri 5/92:13 pmMDE - CHS
1 stop17h 25mSpirit Airlines
Deal found 3/26$395
This Avianca Connect deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2510:32 amCHS - MDE
1 stop9h 18mMultiple Airlines
Wed 4/3010:20 amMDE - CHS
1 stop7h 15mMultiple Airlines
Deal found 3/26$407
This Avianca Connect deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2510:32 amCHS - BOG
1 stop8h 27mMultiple Airlines
Wed 4/309:00 amBOG - CHS
1 stop8h 35mMultiple Airlines
Deal found 3/26$427
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/159:40 amCHS - BOG
1 stop10h 35mDelta
Thu 5/227:00 amBOG - CHS
2 stops10h 58mDelta
Deal found 3/26$513
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/97:10 pmCHS - CTG
1 stop20h 00mAmerican Airlines
Fri 5/163:10 pmCTG - CHS
1 stop6h 50mAmerican Airlines
Deal found 3/27$517
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1510:32 amCHS - BOG
1 stop11h 45mAmerican Airlines
Thu 5/222:10 pmBOG - CHS
1 stop18h 42mAmerican Airlines
Deal found 3/26$522
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/114:50 pmCHS - BOG
1 stop12h 20mUnited Airlines
Thu 11/208:15 amBOG - CHS
1 stop13h 39mUnited Airlines
Deal found 3/26$523
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/35:35 amCHS - CTG
1 stop8h 37mDelta
Fri 5/93:07 amCTG - CHS
2 stops14h 51mDelta
Deal found 3/27$536
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/175:02 pmCHS - MDE
1 stop20h 48mAmerican Airlines
Sat 5/246:00 amMDE - CHS
1 stop9h 22mAmerican Airlines
Deal found 3/27$552
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/176:37 amCHS - MDE
2 stops13h 23mDelta
Sat 5/245:27 amMDE - CHS
2 stops12h 31mDelta
Deal found 3/27$554

Cheapflights Fare Finder

Customize your flight search to find flights from Charleston to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Charleston to South America that are best for you.

Fly from

Charleston

Fly to

South America

Route

Depart

Return

Price

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Sat 5/3

7:15 pm-12:07 pm

1 stop17h 52m

Cartagena Rafael Nunez

Sat 5/10

1:15 pm-8:38 am

1 stop18h 23m

$268

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Fri 5/9

4:30 pm-12:10 pm

2 stops20h 40m

Cartagena Rafael Nunez

Fri 5/16

1:15 pm-8:38 am

1 stop18h 23m

$349

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Sun 5/4

10:25 am-1:15 pm

1 stop27h 50m

Medellín Jose Maria Cordova Intl

Fri 5/9

2:13 pm-8:38 am

1 stop17h 25m

$395

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Fri 4/25

10:32 am-6:50 pm

1 stop9h 18m

Medellín Jose Maria Cordova Intl

Wed 4/30

10:20 am-6:35 pm

1 stop7h 15m

$407

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

Fri 4/25

10:32 am-5:59 pm

1 stop8h 27m

Bogotá El Dorado

Wed 4/30

9:00 am-6:35 pm

1 stop8h 35m

$427

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

Thu 5/15

9:40 am-7:15 pm

1 stop10h 35m

Bogotá El Dorado

Thu 5/22

7:00 am-6:58 pm

2 stops10h 58m

$513

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Fri 5/9

7:10 pm-2:10 pm

1 stop20h 00m

Cartagena Rafael Nunez

Fri 5/16

3:10 pm-11:00 pm

1 stop6h 50m

$517

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

Thu 5/15

10:32 am-9:17 pm

1 stop11h 45m

Bogotá El Dorado

Thu 5/22

2:10 pm-9:52 am

1 stop18h 42m

$522

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Sat 5/3

5:35 am-1:12 pm

1 stop8h 37m

Cartagena Rafael Nunez

Fri 5/9

3:07 am-6:58 pm

2 stops14h 51m

$536

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Sat 5/17

5:02 pm-12:50 pm

1 stop20h 48m

Medellín Jose Maria Cordova Intl

Sat 5/24

6:00 am-4:22 pm

1 stop9h 22m

$552

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Showing 1-10 of 39 results
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Best time to book a flight from Charleston to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to South America

What is the cheapest month to book a flight from Charleston to South America?

Currently, May is the cheapest month in which you can book a flight from Charleston to South America (average of $359). Flying from Charleston to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to SA?

Find hourly flight availability from Charleston to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Charleston to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated March 28, 2025.
Azul
8.0
Very good
772 reviews

Entertainment

7.5

Overall

8.0

Food

7.1

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Azul
8.0
Very good
772 reviews
Azul
8.0
Very good
772 reviews

Entertainment

7.5

Overall

8.0

Food

7.1

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Delta
8.0
Very good
7,896 reviews
Azul
8.0
Very good
772 reviews

Entertainment

7.5

Overall

8.0

Food

7.1

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
LATAM Airlines
7.5
Good
1,750 reviews
Azul
8.0
Very good
772 reviews

Entertainment

7.5

Overall

8.0

Food

7.1

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Copa Airlines
7.5
Good
1,395 reviews
Azul
8.0
Very good
772 reviews

Entertainment

7.5

Overall

8.0

Food

7.1

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
United Airlines
7.4
Good
8,603 reviews
Azul
8.0
Very good
772 reviews

Entertainment

7.5

Overall

8.0

Food

7.1

Comfort

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

Related info for your journey

Find useful and relevant information for your journey from Charleston to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to South America?

    For a flight from Charleston to South America, you will be flying from Charleston. Charleston (CHS) is just 10.2 mi from the center of the city.

  • What are the cheapest airlines to fly from Charleston to South America one-way?

    The cheapest airlines for a one-way flight from Charleston to South America are American Airlines ($357), Copa Airlines ($421), and Delta ($733).

  • What are the most popular routes from Charleston to South America?

    Most travelers choose Charleston - Lima J Chavez Intl, Charleston - Cartagena Rafael Nunez or Charleston - Sao Paulo Guarulhos Intl when deciding on the best route from Charleston to South America.

  • Can I find deals for flights from Charleston to South America that include hotel bookings?

    Yes. In addition to deals on Charleston to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to South America.

  • Can I find deals for business class flights from Charleston to South America?

    Yes. Cheapflights offers flight deals from Charleston to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to South America?

    Currently, May is the cheapest month in which you can book a flight from Charleston to South America (average of $359). Flying from Charleston to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Charleston to South America

Discover the top 4 airlines that operate flights from Charleston to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$199Average$376FlexibilityNo cancel feeOn-time65%
DeltaCheapest$355Average$828FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$405Average$838FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$544Average$904FlexibilityNo cancel feeOn-time81%
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