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South America

$252+ Cheap flights from Charleston (CHS) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BOG
avr. 22 — avr. 291
mar. 4/22
mar. 4/29
1 adult, Economy
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Cheap flight deals from Charleston to South America

Keep the following information in mind while searching for Charleston to South America flight deals. Data was last updated avril 17, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$466
(Mytrip)

One-way from

$252
(Kiwi.com)
Provider with most accurate pricing for Charleston-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Charleston-Sao Paulo (SAO) flights.
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From Charleston to South America
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One-way flight from Charleston to South America
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Find flight deals from Charleston to South America

Cheapest flights from Charleston to South America
Explore the most affordable flight options available from Charleston to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on avril 17, 2025.

This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 5/146:00 amCHS - BOG
2 stops32h 05mSpirit Airlines
lun. 5/192:07 pmBOG - CHS
3 stops31h 02mSpirit Airlines
Deal found 4/17$466
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/266:12 amCHS - CTG
1 stop6h 53mAmerican Airlines
sam. 9/61:55 pmCTG - CHS
1 stop7h 57mAmerican Airlines
Deal found 4/17$491
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 5/159:43 amCHS - MDE
1 stop28h 32mMultiple Airlines
lun. 5/196:20 pmMDE - CHS
2 stops37h 54mMultiple Airlines
Deal found 4/17$492
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 5/1510:45 amCHS - CTG
2 stops12h 59mDelta
lun. 5/196:46 amCTG - CHS
2 stops15h 58mDelta
Deal found 4/17$521
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 8/2710:52 amCHS - MDE
1 stop13h 43mAmerican Airlines
sam. 9/65:50 amMDE - CHS
1 stop16h 02mAmerican Airlines
Deal found 4/17$533
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 5/159:43 amCHS - CTG
1 stop27h 27mMultiple Airlines
lun. 5/199:38 amCTG - CHS
2 stops35h 31mMultiple Airlines
Deal found 4/17$548
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 8/276:35 amCHS - MDE
2 stops15h 35mUnited Airlines
sam. 9/69:45 amMDE - CHS
2 stops24h 05mUnited Airlines
Deal found 4/17$549
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/410:26 amCHS - UIO
1 stop15h 19mAmerican Airlines
lun. 9/296:40 amUIO - CHS
1 stop15h 12mAmerican Airlines
Deal found 4/17$581
This LATAM Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/112:15 pmCHS - LIM
2 stops20h 45mLATAM Airlines
lun. 9/158:50 amLIM - CHS
2 stops13h 51mLATAM Airlines
Deal found 4/17$589
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/14:30 pmCHS - LIM
2 stops14h 55mDelta
dim. 9/1412:15 amLIM - CHS
2 stops19h 26mDelta
Deal found 4/16$593
This Copa Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 5/99:53 amCHS - MDE
2 stops13h 59mCopa Airlines
lun. 5/1211:29 amMDE - CHS
2 stops21h 42mCopa Airlines
Deal found 4/17$595
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/18:10 pmCHS - LIM
1 stop8h 10mAmerican Airlines
lun. 9/1510:00 pmLIM - CHS
1 stop20h 20mAmerican Airlines
Deal found 4/17$597

Cheapflights Fare Finder

Customize your flight search to find flights from Charleston to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated avril 17, 2025.
Use the filters below to find and compare flights from Charleston to South America that are best for you.

Fly from

Charleston

Fly to

South America

Route

Depart

Return

Price

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

mer. 5/14

6:00 am-1:05 pm

2 stops32h 05m

Bogotá El Dorado

lun. 5/19

2:07 pm-10:09 pm

3 stops31h 02m

$466

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

mar. 8/26

6:12 am-12:05 pm

1 stop6h 53m

Cartagena Rafael Nunez

sam. 9/6

1:55 pm-10:52 pm

1 stop7h 57m

$491

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

jeu. 5/15

9:43 am-1:15 pm

1 stop28h 32m

Medellín Jose Maria Cordova Intl

lun. 5/19

6:20 pm-9:14 am

2 stops37h 54m

$492

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

jeu. 5/15

10:45 am-10:44 pm

2 stops12h 59m

Cartagena Rafael Nunez

lun. 5/19

6:46 am-11:44 pm

2 stops15h 58m

$521

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

mer. 8/27

10:52 am-11:35 pm

1 stop13h 43m

Medellín Jose Maria Cordova Intl

sam. 9/6

5:50 am-10:52 pm

1 stop16h 02m

$533

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

jeu. 5/15

9:43 am-12:10 pm

1 stop27h 27m

Cartagena Rafael Nunez

lun. 5/19

9:38 am-10:09 pm

2 stops35h 31m

$548

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

mer. 8/27

6:35 am-9:10 pm

2 stops15h 35m

Medellín Jose Maria Cordova Intl

sam. 9/6

9:45 am-10:50 am

2 stops24h 05m

$549

CharlestonQuito

CHS - UIO

CHSUIO

Charleston

lun. 8/4

10:26 am-12:45 am

1 stop15h 19m

Quito Mariscal Sucr

lun. 9/29

6:40 am-10:52 pm

1 stop15h 12m

$581

CharlestonLima

CHS - LIM

CHSLIM

Charleston

lun. 9/1

12:15 pm-8:00 am

2 stops20h 45m

Lima J Chavez Intl

lun. 9/15

8:50 am-11:41 pm

2 stops13h 51m

$589

CharlestonLima

CHS - LIM

CHSLIM

Charleston

lun. 9/1

4:30 pm-6:25 am

2 stops14h 55m

Lima J Chavez Intl

dim. 9/14

12:15 am-8:41 pm

2 stops19h 26m

$593

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 47 results
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Best time to book a flight from Charleston to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to South America

What is the cheapest month to book a flight from Charleston to South America?

Currently, May is the cheapest month in which you can book a flight from Charleston to South America (average of $359). Flying from Charleston to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to SA?

Find hourly flight availability from Charleston to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated avril 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Charleston to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated avril 17, 2025.
Azul
8.0
Very good
774 reviews

Boarding

8.1

Crew

8.6

Food

7.1

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Azul
8.0
Very good
774 reviews
Azul
8.0
Very good
774 reviews

Boarding

8.1

Crew

8.6

Food

7.1

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Delta
8.0
Very good
7,917 reviews
Azul
8.0
Very good
774 reviews

Boarding

8.1

Crew

8.6

Food

7.1

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
Copa Airlines
7.6
Good
1,409 reviews
Azul
8.0
Very good
774 reviews

Boarding

8.1

Crew

8.6

Food

7.1

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
LATAM Airlines
7.5
Good
1,761 reviews
Azul
8.0
Very good
774 reviews

Boarding

8.1

Crew

8.6

Food

7.1

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.
United Airlines
7.4
Good
8,667 reviews
Azul
8.0
Very good
774 reviews

Boarding

8.1

Crew

8.6

Food

7.1

Entertainment

7.5

Comfort

8.0

Overall

8.0

Reviews

1 / 14
2.0
Mediocre

Mike,Feb 2025

NVT - LIS

Experience was terrible. Flight cancelled. Missed connection. Replace service with EuroAtlantic airlines. Awful seats, awful food.

Related info for your journey

Find useful and relevant information for your journey from Charleston to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to South America?

    For a flight from Charleston to South America, you will be flying from Charleston. Charleston (CHS) is just 10.2 mi from the center of the city.

  • What are the cheapest airlines to fly from Charleston to South America one-way?

    The cheapest airlines for a one-way flight from Charleston to South America are Copa Airlines ($321), United Airlines ($344), and Delta ($354).

  • What are the most popular routes from Charleston to South America?

    Most travelers choose Charleston - Medellín Jose Maria Cordova Intl, Charleston - Lima J Chavez Intl or Charleston - Cartagena Rafael Nunez when deciding on the best route from Charleston to South America.

  • Can I find deals for flights from Charleston to South America that include hotel bookings?

    Yes. In addition to deals on Charleston to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to South America.

  • Can I find deals for business class flights from Charleston to South America?

    Yes. Cheapflights offers flight deals from Charleston to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to South America?

    Currently, May is the cheapest month in which you can book a flight from Charleston to South America (average of $359). Flying from Charleston to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Charleston to South America

Discover the top 4 airlines that operate flights from Charleston to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated avril 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$199Average$355FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$405Average$894FlexibilityNo cancel feeOn-time71%
DeltaCheapest$405Average$879FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$544Average$906FlexibilityNo cancel feeOn-time81%

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