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$220+ Cheap flights from Panama City, FL to Sioux Falls (ECP - FSD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — FSD
Apr 20 — Apr 271
Sun 4/20
Sun 4/27
1 adult, Economy
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Cheap flight deals from Panama City to Sioux Falls

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Sioux Falls (FSD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 15, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$694
(Delta)

One-way from

$220
(American Airlines)

Popular in

June

Cheapest in

November

Average price

$388
Provider with most accurate pricing for Panama City NW Florida Beaches-Sioux Falls Joe Foss Field flight deals.
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Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Sioux Falls Joe Foss Field flights.
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From Panama City NW Florida Beaches to Sioux Falls Joe Foss Field
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One-way flight from Panama City NW Florida Beaches to Sioux Falls Joe Foss Field
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Highest demand for flights based on searches. 25% potential increase in price ($153 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($39 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Panama City to Sioux Falls

Cheapest flights from Panama City to Sioux Falls
Explore the most affordable flight options available from Panama City to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.

This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/33:35 pmECP - FSD
1 stop6h 02mAmerican Airlines
Mon 6/912:06 pmFSD - ECP
2 stops11h 43mAmerican Airlines
Deal found 4/13$414
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/82:47 pmECP - FSD
2 stops8h 57mDelta
Wed 6/115:15 amFSD - ECP
1 stop7h 27mDelta
Deal found 4/15$694

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2025.
Use the filters below to find and compare flights from Panama City to Sioux Falls that are best for you.

Fly from

Panama City

Fly to

Sioux Falls

Route

Depart

Return

Price

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Tue 6/3

3:35 pm-9:37 pm

1 stop6h 02m

Sioux Falls Joe Foss Field

Mon 6/9

12:06 pm-11:49 pm

2 stops11h 43m

$414

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Sun 6/8

2:47 pm-11:44 pm

2 stops8h 57m

Sioux Falls Joe Foss Field

Wed 6/11

5:15 am-12:42 pm

1 stop7h 27m

$694

Panama CitySioux Falls

ECP - FSD

ECPFSD

Panama City NW Florida Beaches

Sun 5/25

11:33 am-5:05 pm

1 stop5h 32m

$220

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/13

Compare providers for flights from Panama City to Sioux Falls

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Sioux Falls in April.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*2 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-Sioux Falls flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Sioux Falls flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Sioux Falls flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Sioux Falls flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Sioux Falls flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Sioux Falls

Have a flexible travel schedule? Discover the best time to fly to Sioux Falls from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Sioux Falls

What is the cheapest month to book a flight from Panama City, Florida to Sioux Falls?

Currently, September is the cheapest month in which you can book a flight from Panama City, Florida to Sioux Falls (average of $334). Flying from Panama City, Florida to Sioux Falls in December is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to FSD?

Find hourly flight availability from Panama City to Sioux Falls. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 15, 2025.

One of the essential ways to save on airfare from Panama City, Florida to Sioux Falls is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 39% on airfare.

Rainfall in Sioux Falls by month

Plan your trip to Sioux Falls by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Sioux Falls ranges from 0.6 - 3.9 inches per month. June is typically the wettest month, when rainfall can reach 3.9 in. January is typically the driest time to visit Sioux Falls when rainfall is around 0.6 in.

Temperature in Sioux Falls by month

Plan your trip to Sioux Falls by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Sioux Falls, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 15.8 F).

Reviews of airlines servicing Sioux Falls

Get insights into the airlines that provide service to Sioux Falls. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sioux Falls. Reviews last updated April 15, 2025.
Delta
8.0
Very good
7,918 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
Delta
8.0
Very good
7,918 reviews
Delta
8.0
Very good
7,918 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,918 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Sioux Falls. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City, Florida to Sioux Falls round-trip?

    Our cheapest airline available from Panama City, Florida to Sioux Falls is Delta. Our recent data shows that you can find tickets from as low as $694 on this airline. An additional option worth looking into is American Airlines, starting at $769.

  • Can I find deals for flights from Panama City to Sioux Falls that include hotel bookings?

    Yes. In addition to deals on Panama City to Sioux Falls flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Sioux Falls?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Sioux Falls.

  • Can I find deals for business class flights from Panama City to Sioux Falls?

    Yes. Cheapflights offers flight deals from Panama City to Sioux Falls by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Sioux Falls?

    Currently, September is the cheapest month in which you can book a flight from Panama City, Florida to Sioux Falls (average of $334). Flying from Panama City, Florida to Sioux Falls in December is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 2 airlines flying from Panama City to Sioux Falls

Discover the top 2 airlines that operate flights from Panama City to Sioux Falls. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$218Average$313FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$267Average$491FlexibilityNo cancel feeOn-time71%

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