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$212+ Cheap flights from Knoxville to Sioux Falls (TYS - FSD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FSD
Apr 16 — Apr 231
Wed 4/16
Wed 4/23
1 adult, Economy
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Cheap flight deals from Knoxville to Sioux Falls

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Sioux Falls (FSD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 11, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$264
(Delta)

One-way from

$212
(Booking.com)

Popular in

August

Cheapest in

September

Average price

$282
Provider with most accurate pricing for Knoxville McGhee Tyson-Sioux Falls Joe Foss Field flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Sioux Falls Joe Foss Field flights.
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From Knoxville McGhee Tyson to Sioux Falls Joe Foss Field
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One-way flight from Knoxville McGhee Tyson to Sioux Falls Joe Foss Field
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Highest demand for flights based on searches. 3% potential increase in price ($15 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($29 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Knoxville to Sioux Falls

Cheapest flights from Knoxville to Sioux Falls
Explore the most affordable flight options available from Knoxville to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2025.

This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/255:30 amTYS - FSD
2 stops7h 14mDelta
Tue 4/295:05 amFSD - TYS
1 stop5h 04mDelta
Deal found 4/10$264
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/195:24 amTYS - FSD
1 stop8h 35mAmerican Airlines
Sun 4/206:21 amFSD - TYS
1 stop7h 03mAmerican Airlines
Deal found 4/10$283
This Mytrip deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1811:13 amTYS - FSD
1 stop8h 14mAllegiant Air
Sun 4/209:45 amFSD - TYS
1 stop23h 38mAllegiant Air
Deal found 4/10$298
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/255:25 pmTYS - FSD
1 stop5h 47mUnited Airlines
Tue 4/293:15 pmFSD - TYS
1 stop6h 07mUnited Airlines
Deal found 4/10$329

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 11, 2025.
Use the filters below to find and compare flights from Knoxville to Sioux Falls that are best for you.

Fly from

Knoxville

Fly to

Sioux Falls

Route

Depart

Return

Price

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Fri 4/25

5:30 am-11:44 am

2 stops7h 14m

Sioux Falls Joe Foss Field

Tue 4/29

5:05 am-11:09 am

1 stop5h 04m

$264

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Sat 4/19

5:24 am-12:59 pm

1 stop8h 35m

Sioux Falls Joe Foss Field

Sun 4/20

6:21 am-2:24 pm

1 stop7h 03m

$283

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Fri 4/18

11:13 am-6:27 pm

1 stop8h 14m

Sioux Falls Joe Foss Field

Sun 4/20

9:45 am-10:23 am

1 stop23h 38m

$298

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Fri 4/25

5:25 pm-10:12 pm

1 stop5h 47m

Sioux Falls Joe Foss Field

Tue 4/29

3:15 pm-10:22 pm

1 stop6h 07m

$329

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Thu 6/12

5:25 pm-6:32 pm

1 stop26h 07m

$212

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Mon 4/14

6:49 pm-9:25 am

1 stop15h 36m

$259

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Thu 6/12

5:15 pm-11:44 pm

2 stops7h 29m

$265

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Mon 4/14

4:20 pm-10:40 pm

2 stops7h 20m

$455

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/10

Compare providers for flights from Knoxville to Sioux Falls

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Sioux Falls in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Sioux Falls flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Sioux Falls flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Sioux Falls flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Sioux Falls flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Sioux Falls flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Sioux Falls

Have a flexible travel schedule? Discover the best time to fly to Sioux Falls from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Sioux Falls

What is the cheapest month to book a flight from Knoxville to Sioux Falls?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Sioux Falls (average of $334). Flying from Knoxville to Sioux Falls in December is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to FSD?

Find hourly flight availability from Knoxville to Sioux Falls. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 11, 2025.

One of the essential ways to save on airfare from Knoxville to Sioux Falls is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 24% on airfare.

Rainfall in Sioux Falls by month

Plan your trip to Sioux Falls by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Sioux Falls ranges from 0.6 - 3.9 inches per month. June is typically the wettest month, when rainfall can reach 3.9 in. January is typically the driest time to visit Sioux Falls when rainfall is around 0.6 in.

Temperature in Sioux Falls by month

Plan your trip to Sioux Falls by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Sioux Falls, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 15.8 F).

Reviews of airlines servicing Sioux Falls

Get insights into the airlines that provide service to Sioux Falls. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sioux Falls. Reviews last updated April 11, 2025.
Delta
8.0
Very good
7,911 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,911 reviews
Delta
8.0
Very good
7,911 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,636 reviews
Delta
8.0
Very good
7,911 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,911 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,911 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
6.0
Okay
3,277 reviews
Delta
8.0
Very good
7,911 reviews

Crew

8.5

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Sioux Falls. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Knoxville to Sioux Falls round-trip?

    Flying on Delta is currently your cheapest option to Sioux Falls, with prices starting at $264. Additional round-trip tickets that might be worth considering are offered by American Airlines and Allegiant Air, with the lowest prices starting at $283 and $298, respectively. Users have found that Delta is 37% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Knoxville to Sioux Falls one-way?

    The cheapest airlines for a one-way flight from Knoxville to Sioux Falls are Frontier ($212), Allegiant Air ($259), and Delta ($265).

  • Can I find deals for flights from Knoxville to Sioux Falls that include hotel bookings?

    Yes. In addition to deals on Knoxville to Sioux Falls flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Sioux Falls?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Sioux Falls.

  • Can I find deals for business class flights from Knoxville to Sioux Falls?

    Yes. Cheapflights offers flight deals from Knoxville to Sioux Falls by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Sioux Falls?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Sioux Falls (average of $334). Flying from Knoxville to Sioux Falls in December is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Yankton

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Top 3 airlines flying from Knoxville to Sioux Falls

Discover the top 3 airlines that operate flights from Knoxville to Sioux Falls. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$195Average$597FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$227Average$446FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$359Average$573FlexibilityNo cancel feeOn-time69%

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