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$373+ Cheap flights from Des Moines (DSM) to Sao Paulo, Brazil (SAO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAO
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
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Cheap flight deals from Des Moines to Sao Paulo

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Sao Paulo (SAO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 31, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$790
(American Airlines)

One-way from

$373
(Avianca)

Popular in

June

Cheapest in

April

Average price

$977
Provider with most accurate pricing for Des Moines-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Sao Paulo (SAO) flights.
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From Des Moines to Sao Paulo (SAO)
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One-way flight from Des Moines to Sao Paulo (SAO)
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Highest demand for flights based on searches. 20% potential increase in price ($296 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($113 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Des Moines to Sao Paulo

Cheapest flights from Des Moines to Sao Paulo
Explore the most affordable flight options available from Des Moines to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/145:13 amDSM - GRU
1 stop24h 02mAmerican Airlines
Wed 5/2110:00 pmGRU - DSM
1 stop16h 21mAmerican Airlines
Deal found 3/30$790
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/143:20 pmDSM - GRU
1 stop14h 15mUnited Airlines
Wed 5/2110:20 pmGRU - DSM
1 stop13h 50mUnited Airlines
Deal found 3/30$800
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1411:26 amDSM - GRU
3 stops25h 54mMultiple Airlines
Wed 5/216:40 amGRU - DSM
3 stops42h 47mMultiple Airlines
Deal found 3/30$820
This Expedia deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/152:15 pmDSM - GRU
1 stop13h 25mLATAM Airlines
Wed 5/213:40 amGRU - DSM
2 stops33h 01mLATAM Airlines
Deal found 3/31$932
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/811:04 amDSM - GRU
2 stops17h 11mDelta
Fri 9/1910:50 pmGRU - DSM
1 stop13h 28mDelta
Deal found 3/30$1,079
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/148:07 amDSM - GRU
2 stops19h 28mAvianca
Tue 5/201:45 amGRU - DSM
2 stops22h 07mAvianca
Deal found 3/30$1,589
This Copa Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/88:00 amDSM - GRU
2 stops20h 30mCopa Airlines
Thu 9/181:40 amGRU - DSM
2 stops21h 11mCopa Airlines
Deal found 3/31$1,756

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from Des Moines to Sao Paulo that are best for you.

Fly from

Des Moines

Fly to

Sao Paulo

Route

Depart

Return

Price

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 5/14

5:13 am-7:15 am

1 stop24h 02m

Sao Paulo Guarulhos Intl

Wed 5/21

10:00 pm-12:21 pm

1 stop16h 21m

$790

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 5/14

11:26 am-9:30 am

2 stops20h 04m

Sao Paulo Guarulhos Intl

Wed 5/21

9:30 pm-2:42 pm

2 stops19h 12m

$800

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 5/14

11:26 am-3:20 pm

3 stops25h 54m

Sao Paulo Guarulhos Intl

Wed 5/21

6:40 am-11:27 pm

3 stops42h 47m

$820

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Thu 5/15

2:15 pm-5:40 am

1 stop13h 25m

Sao Paulo Guarulhos Intl

Wed 5/21

3:40 am-10:41 am

2 stops33h 01m

$932

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 9/8

11:04 am-6:15 am

2 stops17h 11m

Sao Paulo Guarulhos Intl

Fri 9/19

10:50 pm-10:18 am

1 stop13h 28m

$1,079

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 5/14

8:07 am-5:35 am

2 stops19h 28m

Sao Paulo Guarulhos Intl

Tue 5/20

1:45 am-9:52 pm

2 stops22h 07m

$1,589

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 9/8

8:00 am-6:30 am

2 stops20h 30m

Sao Paulo Guarulhos Intl

Thu 9/18

1:40 am-8:51 pm

2 stops21h 11m

$1,756

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Tue 4/15

8:00 am-5:35 am

2 stops19h 35m

$373

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Tue 4/15

11:30 am-5:40 am

1 stop16h 10m

$459

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Fri 4/11

8:00 am-5:35 am

2 stops19h 35m

$558

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Compare providers for flights from Des Moines to Sao Paulo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Sao Paulo in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*1 star
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Sao Paulo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Sao Paulo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Sao Paulo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Sao Paulo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Sao Paulo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Sao Paulo

Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Sao Paulo

What is the cheapest month to book a flight from Des Moines to Sao Paulo?

Currently, October is the cheapest month in which you can book a flight from Des Moines to Sao Paulo (average of $691). Flying from Des Moines to Sao Paulo in December is currently the most expensive (average of $1,209). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Sao Paulo by month

Plan your trip to Sao Paulo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Sao Paulo ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit Sao Paulo when rainfall is around 0.8 in.

Temperature in Sao Paulo by month

Plan your trip to Sao Paulo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Sao Paulo, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing Sao Paulo

Get insights into the airlines that provide service to Sao Paulo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sao Paulo. Reviews last updated March 31, 2025.
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,899 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,400 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,754 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,614 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Sao Paulo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Sao Paulo?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Sao Paulo from Des Moines. Booking flights from Des Moines (DSM) to Sao Paulo should be relatively easy as there are 0 daily outbound flights to Sao Paulo from 1 airline.

  • What are the cheapest airlines flying from Des Moines to Sao Paulo round-trip?

    Flying on American Airlines is currently your cheapest option to Sao Paulo, with prices starting at $790. Additional round-trip tickets that might be worth considering are offered by United Airlines and LATAM Airlines, with the lowest prices starting at $800 and $932, respectively. American Airlines is currently priced 30% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Sao Paulo that include hotel bookings?

    Yes. In addition to deals on Des Moines to Sao Paulo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Sao Paulo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Sao Paulo.

  • Can I find deals for business class flights from Des Moines to Sao Paulo?

    Yes. Cheapflights offers flight deals from Des Moines to Sao Paulo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Sao Paulo?

    Currently, October is the cheapest month in which you can book a flight from Des Moines to Sao Paulo (average of $691). Flying from Des Moines to Sao Paulo in December is currently the most expensive (average of $1,209). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
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Alternative routes for Des Moines to Sao Paulo

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to Guarulhos Intl flights
Omaha to Guarulhos Intl flights
Moline to Guarulhos Intl flights

Top airline flying from Des Moines to Sao Paulo

Discover the top airline that operate flights from Des Moines to Sao Paulo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$677Average$861FlexibilityNo cancel feeOn-timeN/A
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