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Santo Domingo

$94+ Cheap flights from South Carolina to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/5. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SDQ
Feb 28 — Mar 71
Fri 2/28
Fri 3/7
1 adult, Economy
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Cheap flight deals from South Carolina to Santo Domingo

Keep the following information in mind while searching for South Carolina to Santo Domingo flight deals. Data was last updated February 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$208
(Gotogate)

One-way from

$94
(Booking.com)
Provider with most accurate pricing for Myrtle Beach Intl-Santo Domingo Las Americas flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Santo Domingo Las Americas flights.
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From South Carolina to Santo Domingo Las Americas
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One-way flight from South Carolina to Santo Domingo Las Americas
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Find flight deals from South Carolina to Santo Domingo

Cheapest flights from South Carolina to Santo Domingo
Explore the most affordable flight options available from South Carolina to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2025.

This Gotogate deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/317:54 pmCLT - SDQ
1 stop17h 50mFrontier
Mon 4/712:02 pmSDQ - CLT
1 stop8h 05mFrontier
Deal found 2/21$208
This FlightHub deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/47:00 amCLT - SDQ
1 stop8h 49mMultiple Airlines
Mon 4/712:02 pmSDQ - CLT
1 stop8h 05mMultiple Airlines
Deal found 2/22$267
This FlightHub deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/27:00 amCLT - SDQ
1 stop8h 39mSpirit Airlines
Sat 4/53:44 pmSDQ - CLT
1 stop8h 48mSpirit Airlines
Deal found 2/21$311
This FlightHub deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/32:15 pmCHS - SDQ
2 stops25h 34mSpirit Airlines
Mon 4/74:44 pmSDQ - CHS
1 stop17h 13mSpirit Airlines
Deal found 2/21$358
This Mytrip deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/510:48 amCHS - SDQ
1 stop4h 56mMultiple Airlines
Wed 5/710:19 amSDQ - CHS
3 stops31h 49mMultiple Airlines
Deal found 2/22$395
This Mytrip deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/74:35 pmGSP - SDQ
2 stops22h 12mMultiple Airlines
Sat 4/53:44 pmSDQ - GSP
2 stops22h 10mMultiple Airlines
Deal found 2/22$427
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/312:55 pmCHS - SDQ
1 stop11h 50mDelta
Mon 4/77:16 amSDQ - CHS
1 stop9h 07mDelta
Deal found 2/21$431
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/127:46 pmSAV - SDQ
1 stop15h 29mAmerican Airlines
Thu 4/2412:15 pmSDQ - SAV
1 stop11h 44mAmerican Airlines
Deal found 2/22$465
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/127:18 pmCHS - SDQ
1 stop15h 57mAmerican Airlines
Thu 4/174:20 pmSDQ - CHS
1 stop17h 31mAmerican Airlines
Deal found 2/21$478
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2110:26 amGSP - SDQ
2 stops12h 14mAmerican Airlines
Tue 6/108:00 amSDQ - GSP
1 stop11h 27mAmerican Airlines
Deal found 2/22$479
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/256:45 amSAV - SDQ
1 stop6h 11mDelta
Wed 3/53:22 pmSDQ - SAV
1 stop9h 35mDelta
Deal found 2/22$485
This Booking.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/239:45 amMYR - SDQ
1 stop4h 41mSpirit Airlines
Sun 3/24:31 pmSDQ - MYR
1 stop6h 01mSpirit Airlines
Deal found 2/22$493

Find flights from South Carolina to Santo Domingo within your budget

Customize your flight search to find flights from South Carolina to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2025.

Fly from

South Carolina

Fly to

Santo Domingo

Route

Depart

Return

Price

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

Mon 3/31

7:54 pm-1:44 pm

1 stop17h 50m

Santo Domingo Las Americas

Mon 4/7

12:02 pm-8:07 pm

1 stop8h 05m

$208

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

Fri 4/4

7:00 am-3:49 pm

1 stop8h 49m

Santo Domingo Las Americas

Mon 4/7

12:02 pm-8:07 pm

1 stop8h 05m

$267

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

Wed 4/2

7:00 am-3:39 pm

1 stop8h 39m

Santo Domingo Las Americas

Sat 4/5

3:44 pm-12:32 am

1 stop8h 48m

$311

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Thu 4/3

2:15 pm-3:49 pm

2 stops25h 34m

Santo Domingo Las Americas

Mon 4/7

4:44 pm-9:57 am

1 stop17h 13m

$358

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Wed 3/5

10:48 am-4:44 pm

1 stop4h 56m

Santo Domingo Las Americas

Wed 5/7

10:19 am-6:08 pm

3 stops31h 49m

$395

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Fri 3/7

4:35 pm-3:47 pm

2 stops22h 12m

Santo Domingo Las Americas

Sat 4/5

3:44 pm-1:54 pm

2 stops22h 10m

$427

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Thu 4/3

12:55 pm-12:45 am

1 stop11h 50m

Santo Domingo Las Americas

Mon 4/7

7:16 am-4:23 pm

1 stop9h 07m

$431

SavannahSanto Domingo

SAV - SDQ

SAVSDQ

Savannah/Hilton Head

Sat 4/12

7:46 pm-11:15 am

1 stop15h 29m

Santo Domingo Las Americas

Thu 4/24

12:15 pm-11:59 pm

1 stop11h 44m

$465

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Sat 4/12

7:18 pm-11:15 am

1 stop15h 57m

Santo Domingo Las Americas

Thu 4/17

4:20 pm-9:51 am

1 stop17h 31m

$478

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Wed 5/21

10:26 am-10:40 pm

2 stops12h 14m

Santo Domingo Las Americas

Tue 6/10

8:00 am-7:27 pm

1 stop11h 27m

$479

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/21

Showing 1-10 of 22 results
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Best time to book a flight from South Carolina to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to Santo Domingo

Get recent, data-driven insights about flights from South Carolina to Santo Domingo including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Santo Domingo (average of $362). Flying from South Carolina to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SDQ?

Find hourly flight availability from South Carolina to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 23, 2025.

When flying from South Carolina to Santo Domingo, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

Temperature in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated February 23, 2025.
See what other customers who have flown with Delta, JetBlue and United Airlines from South Carolina to Santo Domingo have to say. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Crew

8.5

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,203 reviews
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Crew

8.5

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

JetBlue
7.4
Good
3,068 reviews
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Crew

8.5

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
8,754 reviews
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Crew

8.5

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Crew

8.5

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Spirit Airlines
6.3
Okay
8,012 reviews
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Crew

8.5

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santo Domingo from South Carolina?

    If you book a flight to Santo Domingo from South Carolina, you will be flying to Las Americas, which is the city’s only airport. Santo Domingo Las Americas (SDQ) is located 17.5 mi from the center of Santo Domingo.

  • What are the cheapest airlines to fly from South Carolina to Santo Domingo one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $94. Users have also found prices from $153 and $276 on Spirit Airlines and Delta, respectively.

  • What are the most popular routes from South Carolina to Santo Domingo?

    The most popular route from South Carolina to Santo Domingo is Charlotte Douglas - Santo Domingo Las Americas. You may also consider Greenville - Santo Domingo Las Americas or Savannah/Hilton Head - Santo Domingo Las Americas.

  • Can I find deals for flights from South Carolina to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on South Carolina to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santo Domingo.

  • Can I find deals for business class flights from South Carolina to Santo Domingo?

    Yes. Cheapflights offers flight deals from South Carolina to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Santo Domingo (average of $362). Flying from South Carolina to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
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Alternative routes for South Carolina to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Santo Domingo

Discover the top 2 airlines that operate flights from South Carolina to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$320Average$643FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$410Average$662FlexibilityNo cancel feeOn-time71%
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