HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santo Domingo

$122+ Cheap flights from South Carolina to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SDQ
Jan 26 — Feb 21
Sun 1/26
Sun 2/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Santo Domingo with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from South Carolina (USSC) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$281
(Mytrip)

One-way from

$122
(FlightHub)
From South Carolina to Santo Domingo Las Americas
Search Deals
One-way flight from South Carolina to Santo Domingo Las Americas
Search Deals

Find flight deals from South Carolina to Santo Domingo

Cheapest flights from South Carolina to Santo Domingo
Explore the most affordable flight options available from South Carolina to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This Mytrip deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/612:55 pmCLT - SDQ
1 stop21h 49mFrontier
Sun 3/91:28 pmSDQ - CLT
2 stops29h 15mFrontier
Deal found 1/21$281
This eDestinos deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/78:55 pmCLT - SDQ
1 stop15h 00mSpirit Airlines
Mon 2/1012:51 pmSDQ - CLT
1 stop8h 44mSpirit Airlines
Deal found 1/20$284
This Booking.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/209:11 amCLT - SDQ
1 stop25h 23mMultiple Airlines
Sat 3/14:46 pmSDQ - CLT
1 stop7h 55mMultiple Airlines
Deal found 1/20$290
This CheapOair deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/111:21 amSAV - SDQ
2 stops24h 47mFrontier
Mon 3/3112:04 pmSDQ - SAV
1 stop9h 20mFrontier
Deal found 1/20$339
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/211:00 pmCHS - SDQ
2 stops9h 49mAmerican Airlines
Tue 2/47:30 amSDQ - CHS
2 stops10h 48mAmerican Airlines
Deal found 1/20$425
This CheapOair deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/710:37 pmMYR - SDQ
1 stop16h 10mSpirit Airlines
Fri 3/144:44 pmSDQ - MYR
2 stops24h 28mSpirit Airlines
Deal found 1/21$426
This JetBlue Airways deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/285:14 pmCHS - SDQ
1 stop6h 45mJetBlue
Mon 3/35:30 amSDQ - CHS
1 stop11h 47mJetBlue
Deal found 1/21$431
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/47:00 amCHS - SDQ
1 stop10h 31mDelta
Wed 6/112:30 pmSDQ - CHS
1 stop7h 38mDelta
Deal found 1/21$462
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/18:16 pmSAV - SDQ
1 stop14h 39mAmerican Airlines
Tue 4/15:00 amSDQ - SAV
1 stop14h 39mAmerican Airlines
Deal found 1/20$465
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/136:00 amCLT - SDQ
1 stop8h 00mUnited Airlines
Tue 9/301:10 pmSDQ - CLT
1 stop7h 48mUnited Airlines
Deal found 1/20$475
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/137:00 amCLT - SDQ
1 stop11h 16mDelta
Sat 3/227:16 amSDQ - CLT
1 stop10h 55mDelta
Deal found 1/20$485
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2312:59 pmSAV - SDQ
1 stop10h 57mDelta
Fri 2/77:05 amSDQ - SAV
1 stop11h 05mDelta
Deal found 1/20$485

Find flights from South Carolina to Santo Domingo within your budget

Customize your flight search to find flights from South Carolina to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

Thu 3/6

12:55 pm-11:44 am

1 stop21h 49m

Santo Domingo Las Americas

Sun 3/9

1:28 pm-6:43 pm

2 stops29h 15m

$281

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

Fri 2/7

8:55 pm-12:55 pm

1 stop15h 00m

Santo Domingo Las Americas

Mon 2/10

12:51 pm-8:35 pm

1 stop8h 44m

$284

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

Tue 2/11

6:10 am-3:54 pm

1 stop8h 44m

Santo Domingo Las Americas

Thu 2/13

4:00 pm-7:08 am

1 stop16h 08m

$285

SavannahSanto Domingo

SAV - SDQ

SAVSDQ

Savannah/Hilton Head

Sat 3/1

11:21 am-1:08 pm

2 stops24h 47m

Santo Domingo Las Americas

Mon 3/31

12:04 pm-9:24 pm

1 stop9h 20m

$339

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Fri 3/7

10:37 pm-3:47 pm

1 stop16h 10m

Santo Domingo Las Americas

Fri 3/14

4:44 pm-5:12 pm

2 stops24h 28m

$426

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Fri 2/28

5:14 pm-1:58 am

1 stop7h 44m

Santo Domingo Las Americas

Sun 3/2

2:28 am-12:19 pm

1 stop10h 51m

$431

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Thu 4/3

7:50 pm-1:20 pm

1 stop17h 30m

Santo Domingo Las Americas

Mon 4/7

6:50 am-11:42 pm

1 stop16h 52m

$437

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

Wed 6/4

7:00 am-5:31 pm

1 stop10h 31m

Santo Domingo Las Americas

Wed 6/11

2:30 pm-10:08 pm

1 stop7h 38m

$462

SavannahSanto Domingo

SAV - SDQ

SAVSDQ

Savannah/Hilton Head

Sat 3/1

8:16 pm-11:55 am

1 stop14h 39m

Santo Domingo Las Americas

Tue 4/1

5:00 am-7:39 pm

1 stop14h 39m

$465

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

Thu 3/13

2:52 pm-12:54 am

1 stop10h 02m

Santo Domingo Las Americas

Tue 3/25

7:16 am-6:50 pm

1 stop11h 34m

$485

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 34 results
1
2
3
4

Best time to book a flight from South Carolina to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to Santo Domingo

Get recent, data-driven insights about flights from South Carolina to Santo Domingo including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Santo Domingo (average of $362). Flying from South Carolina to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SDQ?

Find hourly flight availability from South Carolina to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

When flying from South Carolina to Santo Domingo, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

Temperature in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated January 21, 2025.
See what other customers who have flown with Delta, Frontier and Spirit Airlines from South Carolina to Santo Domingo have to say. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,521 reviews

Food

7.3

Comfort

8.0

Crew

8.6

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,521 reviews
Delta
8.0
Very good
8,521 reviews

Food

7.3

Comfort

8.0

Crew

8.6

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines
7.7
Good
1,662 reviews
Delta
8.0
Very good
8,521 reviews

Food

7.3

Comfort

8.0

Crew

8.6

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

JetBlue
7.4
Good
3,200 reviews
Delta
8.0
Very good
8,521 reviews

Food

7.3

Comfort

8.0

Crew

8.6

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
8,984 reviews
Delta
8.0
Very good
8,521 reviews

Food

7.3

Comfort

8.0

Crew

8.6

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,521 reviews

Food

7.3

Comfort

8.0

Crew

8.6

Boarding

8.2

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santo Domingo from South Carolina?

    If you book a flight to Santo Domingo from South Carolina, you will be flying to Las Americas, which is the city’s only airport. Santo Domingo Las Americas (SDQ) is located 17.5 mi from the center of Santo Domingo.

  • What are the cheapest airlines to fly from South Carolina to Santo Domingo one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $122. Users have also found prices from $130 and $199 on Spirit Airlines and Delta, respectively.

  • What are the most popular routes from South Carolina to Santo Domingo?

    The most popular route from South Carolina to Santo Domingo is Charlotte Douglas - Santo Domingo Las Americas. You may also consider Charleston - Santo Domingo Las Americas or Greenville - Santo Domingo Las Americas.

  • Can I find deals for flights from South Carolina to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on South Carolina to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santo Domingo.

  • Can I find deals for business class flights from South Carolina to Santo Domingo?

    Yes. Cheapflights offers flight deals from South Carolina to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Santo Domingo (average of $362). Flying from South Carolina to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Punta Cana flights
John F Kennedy Intl to Santo Domingo flights
Newark to Punta Cana flights
John F Kennedy Intl to Santiago de los Caballeros flights
Newark to Santiago de los Caballeros flights
Newark to Santo Domingo flights
LaGuardia to Punta Cana flights
O'Hare Intl to Punta Cana flights
Dulles Intl to Punta Cana flights
Boston to Punta Cana flights
Atlanta to Punta Cana flights
Philadelphia to Punta Cana flights
Miami to Santo Domingo flights
Baltimore to Punta Cana flights
LaGuardia to Santo Domingo flights
Boston to Santo Domingo flights
Orlando to Punta Cana flights
Dallas/Fort Worth to Punta Cana flights
Reagan-National to Punta Cana flights
Miami to Punta Cana flights
Orlando to Santo Domingo flights
Fort Lauderdale to Punta Cana flights
Newark to Puerto Plata flights
LaGuardia to Santiago de los Caballeros flights
John F Kennedy Intl to Puerto Plata flights
Midway to Punta Cana flights
Fort Lauderdale to Santo Domingo flights
Charlotte to Punta Cana flights
Detroit to Punta Cana flights
Minneapolis to Punta Cana flights
Hobby to Punta Cana flights
Atlanta to Santo Domingo flights
Boston to Santiago de los Caballeros flights
George Bush Intcntl to Punta Cana flights
Cleveland to Punta Cana flights
Los Angeles to Punta Cana flights
LaGuardia to Puerto Plata flights
Orlando to Santiago de los Caballeros flights
Philadelphia to Santo Domingo flights
Miami to Santiago de los Caballeros flights
Raleigh to Punta Cana flights
Dulles Intl to Santo Domingo flights
Baltimore to Santo Domingo flights
Milwaukee to Punta Cana flights
Cincinnati to Punta Cana flights
Tampa to Punta Cana flights
Seattle to Punta Cana flights
Columbus to Punta Cana flights
San Francisco to Punta Cana flights
O'Hare Intl to Santo Domingo flights

Top 3 airlines flying from South Carolina to Santo Domingo

Discover the top 3 airlines that operate flights from South Carolina to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$210Average$348FlexibilityNo cancel feeOn-time65%
DeltaCheapest$320Average$641FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$410Average$661FlexibilityNo cancel feeOn-time71%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.