What are the cheapest airlines flying from Santiago to Santo Domingo round-trip?

Flying on Copa Airlines is currently your cheapest option to Santo Domingo, with prices starting at $510. Additional round-trip tickets that might be worth considering are offered by Avianca and Iberia, with the lowest prices starting at $561 and $2,962, respectively. Copa Airlines is 1% cheaper than the average price of flights available within the next 90 days to this destination.

What are the cheapest airlines to fly from Santiago to Santo Domingo one-way?

One-way options have recently been found by users for as low as $261 on Avianca. Other airlines that offer cheap prices include Copa Airlines from $330 and Arajet from $416 one-way.

What is the cheapest day to fly from Santiago to Santo Domingo?

Travelers seeking maximum savings on their Santiago to Santo Domingo flight should consider departing on Monday evenings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

What is the cheapest day to fly round-trip from Santiago to Santo Domingo?

Flights from Santiago to Santo Domingo are found to be more expensive on Tuesday. This shouldn't discourage you from searching as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Santo Domingo.

How far in advance should I book a flight from Santiago to Santo Domingo?

Travelers have found it’s best to book a flight 50 days in advance to save up to 19% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 50 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from Santiago to Santo Domingo 1-2 weeks in advance for as low as $470, or $515 for flights within the next 24 hours.

What is the cheapest month to fly from Santiago to Santo Domingo?

October is one of the best times of the year to fly to Santo Domingo from Santiago. Prices for October average $520 per person but you can even find prices for as low as $241. The most expensive prices can be found in the month of January. Opting for a October flight can save you 20% on your journey compared to booking in January

What is the cheapest time of day to fly from SCL to SDQ?

One of the essential ways to save on airfare from Santiago to Santo Domingo is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 12% on airfare.

Most accurate provider : When it comes to deals on Santiago-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santiago-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santiago-Santo Domingo flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Santiago-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Santiago to Santo Domingo that include hotel bookings?

Yes. In addition to deals on Santiago to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santiago to Santo Domingo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Santo Domingo.

Can I find deals for business class flights from Santiago to Santo Domingo?

Yes. Cheapflights offers flight deals from Santiago to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$261+ Flights from Santiago to Santo Domingo

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Santo Domingo Las Americas are usually found in October or August, booked 85 days in advance, depart on a Monday or Wednesday and return on a Thursday

Cheap flight deals from Santiago to Santo Domingo

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$510 (Copa Airlines)
One-way from	$261 (Priceline)
Popular in	January
Cheapest in	October
Average price	$573

Provider with most accurate pricing for Santiago Arturo Merino Benitez-Santo Domingo Las Americas flight deals.

Search Deals

Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Santo Domingo Las Americas flights.

Search Deals

From Santiago Arturo Merino Benitez to Santo Domingo Las Americas

Search Deals

One-way flight from Santiago Arturo Merino Benitez to Santo Domingo Las Americas

Search Deals

Highest demand for flights based on searches. 13% potential increase in price ($81 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

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Find flight deals from Santiago to Santo Domingo

Cheapest flights from Santiago to Santo Domingo
Explore the most affordable flight options available from Santiago to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

Mon 5/192:24 amSCL - SDQ

1 stop19h 44mCopa Airlines

Fri 6/1311:52 amSDQ - SCL

1 stop11h 16mCopa Airlines

Deal found 4/17

$510

Mon 7/711:55 pmSCL - SDQ

1 stop10h 55mAvianca

Wed 7/306:10 pmSDQ - SCL

1 stop10h 05mAvianca

Deal found 4/17

$561

Wed 6/2511:28 amSCL - SDQ

1 stop15h 17mMultiple Airlines

Wed 7/22:07 pmSDQ - SCL

2 stops14h 53mMultiple Airlines

Deal found 4/17

$1,091

Mon 11/310:45 pmSCL - SDQ

2 stops29h 04mUnited Airlines

Mon 11/102:55 pmSDQ - SCL

2 stops40h 55mUnited Airlines

Deal found 4/17

$1,581

Wed 6/257:00 pmSCL - SDQ

2 stops49h 45mIberia

Wed 7/24:20 pmSDQ - SCL

2 stops52h 30mIberia

Deal found 4/17

$2,962

Tue 10/149:40 pmSCL - SDQ

2 stops21h 12mDelta

Tue 10/217:00 amSDQ - SCL

2 stops24h 00mDelta

Deal found 4/17

$5,039

Best flights from Santiago to Santo Domingo
Discover carefully curated flight deals from Santiago to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2025.

Mon 5/192:24 amSCL - SDQ

1 stop19h 44mCopa Airlines

Fri 6/1311:52 amSDQ - SCL

1 stop11h 16mCopa Airlines

Deal found 4/17

$510

Mon 7/711:55 pmSCL - SDQ

1 stop10h 55mAvianca

Wed 7/306:10 pmSDQ - SCL

1 stop10h 05mAvianca

Deal found 4/17

$561

Wed 6/2511:28 amSCL - SDQ

1 stop15h 17mMultiple Airlines

Wed 7/22:07 pmSDQ - SCL

2 stops14h 53mMultiple Airlines

Deal found 4/17

$1,091

Wed 6/257:00 pmSCL - SDQ

2 stops49h 45mIberia

Wed 7/24:20 pmSDQ - SCL

2 stops52h 30mIberia

Deal found 4/17

$2,962

Tue 10/149:40 pmSCL - SDQ

2 stops21h 12mDelta

Tue 10/217:00 amSDQ - SCL

2 stops24h 00mDelta

Deal found 4/17

$5,039

Last-minute flights from Santiago to Santo Domingo
Discover last-minute flight deals from Santiago to Santo Domingo. Data last updated April 17, 2025 and is based on user searches.

Sun 4/208:40 pmSCL - SDQ

2 stops28h 10mDelta

Fri 4/257:00 amSDQ - SCL

2 stops24h 00mDelta

Deal found 4/17

$5,039

Sat 4/2612:30 amSCL - SDQ

1 stop12h 39mCopa Airlines

Fri 5/911:52 amSDQ - SCL

1 stop10h 52mCopa Airlines

Deal found 4/17

$1,165

Mon 5/192:24 amSCL - SDQ

1 stop19h 44mCopa Airlines

Fri 6/1311:52 amSDQ - SCL

1 stop11h 16mCopa Airlines

Deal found 4/17

$510

One-way flights from Santiago to Santo Domingo
Search for one-way flight options from Santiago to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated April 17, 2025.

Thu 6/2611:55 pmSCL - SDQ

1 stop17h 20mAvianca

Deal found 4/17

$261

Tue 6/243:35 amSCL - SDQ

1 stop11h 45mMultiple Airlines

Deal found 4/17

$302

Wed 4/304:17 amSCL - SDQ

1 stop17h 46mCopa Airlines

Deal found 4/17

$330

Tue 6/243:35 amSCL - SDQ

2 stops26h 24mArajet

Deal found 4/17

$416

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santiago to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 5/19

2:24 am-10:08 pm

1 stop19h 44m

Santo Domingo Las Americas

Fri 6/13

11:52 am-11:08 pm

1 stop11h 16m

$510

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 7/7

11:55 pm-10:50 am

1 stop10h 55m

Santo Domingo Las Americas

Wed 7/30

6:10 pm-4:15 am

1 stop10h 05m

$561

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Wed 6/25

11:28 am-2:45 am

1 stop15h 17m

Santo Domingo Las Americas

Wed 7/2

2:07 pm-5:00 am

2 stops14h 53m

$1,091

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Wed 6/25

7:00 pm-8:45 pm

2 stops49h 45m

Santo Domingo Las Americas

Wed 7/2

4:20 pm-8:50 pm

2 stops52h 30m

$2,962

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Tue 10/14

10:50 pm-5:52 pm

1 stop20h 02m

Santo Domingo Las Americas

Tue 10/21

7:00 am-8:00 am

2 stops24h 00m

$5,039

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Thu 6/26

11:55 pm-5:15 pm

1 stop17h 20m

$261

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Tue 6/24

3:35 am-3:20 pm

1 stop11h 45m

$302

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Wed 4/30

4:17 am-10:03 pm

1 stop17h 46m

$330

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Tue 6/24

3:35 am-5:59 am

2 stops26h 24m

$416

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Compare providers for flights from Santiago to Santo Domingo

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to Santo Domingo in April.

Provider	Price Accuracy	Trust Score*
eDreams	Price Accuracy3 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*2 stars
CheapTicketsDeal	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Santiago-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santiago-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santiago-Santo Domingo flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Santiago-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Santiago with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Santo Domingo

How far ahead should I book a flight from Santiago to Santo Domingo?

Booking 85 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to Santo Domingo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Santiago to Santo Domingo (average of $362). Flying from Santiago to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Santo Domingo by month

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

Temperature in Santo Domingo by month

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

Reviews of airlines servicing Santo Domingo

Delta

8.0

Very good

7,917 reviews

Reviews

1 / 20

6.0

Good

Moishe,Oct 2024

LGA - DEN

The plane had a mechanical error that delayed us by almost an hour. On the positive side the captain kept us all in the know

Delta

8.0

Very good

7,917 reviews

Delta

8.0

Very good

7,917 reviews

Reviews

1 / 20

6.0

Good

Moishe,Oct 2024

LGA - DEN

The plane had a mechanical error that delayed us by almost an hour. On the positive side the captain kept us all in the know

Copa Airlines

7.6

Good

1,409 reviews

Delta

8.0

Very good

7,917 reviews

Reviews

1 / 20

6.0

Good

Moishe,Oct 2024

LGA - DEN

The plane had a mechanical error that delayed us by almost an hour. On the positive side the captain kept us all in the know

Iberia

7.0

Good

2,676 reviews

Delta

8.0

Very good

7,917 reviews

Reviews

1 / 20

6.0

Good

Moishe,Oct 2024

LGA - DEN

The plane had a mechanical error that delayed us by almost an hour. On the positive side the captain kept us all in the know

Avianca

6.7

Okay

2,315 reviews

Delta

8.0

Very good

7,917 reviews

Reviews

1 / 20

6.0

Good

Moishe,Oct 2024

LGA - DEN

The plane had a mechanical error that delayed us by almost an hour. On the positive side the captain kept us all in the know

Related info for your journey

What are the cheapest airlines flying from Santiago to Santo Domingo round-trip?
Flying on Copa Airlines is currently your cheapest option to Santo Domingo, with prices starting at $510. Additional round-trip tickets that might be worth considering are offered by Avianca and Iberia, with the lowest prices starting at $561 and $2,962, respectively. Copa Airlines is 1% cheaper than the average price of flights available within the next 90 days to this destination.
What are the cheapest airlines to fly from Santiago to Santo Domingo one-way?
One-way options have recently been found by users for as low as $261 on Avianca. Other airlines that offer cheap prices include Copa Airlines from $330 and Arajet from $416 one-way.
Can I find deals for flights from Santiago to Santo Domingo that include hotel bookings?
Yes. In addition to deals on Santiago to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santiago to Santo Domingo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Santo Domingo.
Can I find deals for business class flights from Santiago to Santo Domingo?
Yes. Cheapflights offers flight deals from Santiago to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santiago to Santo Domingo?
Currently, January is the cheapest month in which you can book a flight from Santiago to Santo Domingo (average of $362). Flying from Santiago to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Santiago to Santo Domingo

Airline	Cheapest	Average	Flexibility	On-time
Copa Airlines	Cheapest$379	Average$576	FlexibilityNo cancel fee	On-time70%
Avianca	Cheapest$380	Average$545	FlexibilityNo cancel fee	On-time71%

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$261+ Cheap flights from Santiago (SCL) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/26. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santiago to Santo Domingo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Santo Domingo Las Americas are usually found in October or August, booked 85 days in advance, depart on a Monday or Wednesday and return on a Thursday

Cheap flight deals from Santiago to Santo Domingo

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Santiago to Santo Domingo

Cheapest flights from Santiago to Santo DomingoExplore the most affordable flight options available from Santiago to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

Explore the most affordable flight options available from Santiago to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santiago to Santo Domingo that are best for you.

Compare providers for flights from Santiago to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to Santo Domingo in April.

Best time to book a flight from Santiago to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Santiago with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Santo Domingo

How far ahead should I book a flight from Santiago to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Santo Domingo. Price data was last updated on April 11, 2025.

What is the cheapest month to book a flight from Santiago to Santo Domingo?

Rainfall in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average rainfall totals by month.

Temperature in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average temperature totals by month.

Reviews of airlines servicing Santo Domingo

Related info for your journey

Find useful and relevant information for your journey from Santiago to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Santiago to Santo Domingo round-trip?

What are the cheapest airlines to fly from Santiago to Santo Domingo one-way?

Can I find deals for flights from Santiago to Santo Domingo that include hotel bookings?

How can I find direct flights from Santiago to Santo Domingo?

Can I find deals for business class flights from Santiago to Santo Domingo?

What is the cheapest month to book a flight from Santiago to Santo Domingo?

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Alternative routes for Santiago to Santo Domingo

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Top 2 airlines flying from Santiago to Santo Domingo

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Cheapest flights from Santiago to Santo Domingo
Explore the most affordable flight options available from Santiago to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.