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Santo Domingo

$210+ Cheap flights from Missouri to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SDQ
may. 4 — may. 111
dom. 5/4
dom. 5/11
1 adult, Economy
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Cheap flight deals from Missouri to Santo Domingo

Keep the following information in mind while searching for Missouri to Santo Domingo flight deals. Data was last updated abril 29, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$405
(FlightHub)

One-way from

$210
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$544
Provider with most accurate pricing for Kansas City-Santo Domingo Las Americas flight deals.
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Provider most trusted by Cheapflights users for Kansas City-Santo Domingo Las Americas flights.
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From Missouri to Santo Domingo Las Americas
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One-way flight from Missouri to Santo Domingo Las Americas
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Highest demand for flights based on searches. 14% potential increase in price ($100 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($32 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Missouri to Santo Domingo

Cheapest flights from Missouri to Santo Domingo
Explore the most affordable flight options available from Missouri to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 29, 2025.

This FlightHub deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/96:43 pmMCI - SDQ
1 stop6h 27mSpirit Airlines
lun. 9/152:45 amSDQ - MCI
2 stops15h 53mSpirit Airlines
Deal found 4/27$393
This Priceline deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/115:35 pmSTL - SDQ
1 stop14h 33mFrontier
mié. 6/1811:53 amSDQ - STL
2 stops26h 47mFrontier
Deal found 4/27$478
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/12:59 pmMCI - SDQ
1 stop8h 51mDelta
lun. 5/127:00 amSDQ - MCI
1 stop12h 26mDelta
Deal found 4/28$493
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/45:09 amMCI - SDQ
1 stop9h 03mAmerican Airlines
dom. 5/1112:15 pmSDQ - MCI
1 stop11h 23mAmerican Airlines
Deal found 4/27$498
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/295:15 amSTL - SDQ
2 stops12h 05mAmerican Airlines
mar. 8/52:35 pmSDQ - STL
2 stops10h 16mAmerican Airlines
Deal found 4/28$519
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/127:58 pmMCI - SDQ
2 stops24h 47mMultiple Airlines
lun. 5/194:50 pmSDQ - MCI
2 stops22h 00mMultiple Airlines
Deal found 4/28$535
This Booking.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/187:20 pmMCI - SDQ
2 stops12h 48mFrontier
dom. 6/2211:49 amSDQ - MCI
2 stops23h 31mFrontier
Deal found 4/27$553
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/106:32 pmMCI - SDQ
2 stops18h 38mUnited Airlines
lun. 10/133:20 pmSDQ - MCI
2 stops20h 17mUnited Airlines
Deal found 4/28$587
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/105:00 amSTL - SDQ
2 stops19h 50mUnited Airlines
sáb. 7/193:20 pmSDQ - STL
1 stop9h 12mUnited Airlines
Deal found 4/27$899

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 29, 2025.
Use the filters below to find and compare flights from Missouri to Santo Domingo that are best for you.

Fly from

Missouri

Fly to

Santo Domingo

Route

Depart

Return

Price

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

mar. 5/20

5:46 am-3:00 pm

2 stops32h 14m

Santo Domingo Las Americas

lun. 6/2

4:50 pm-10:41 pm

2 stops30h 51m

$466

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

mié. 6/11

5:35 pm-9:08 am

1 stop14h 33m

Santo Domingo Las Americas

mié. 6/18

11:53 am-1:40 pm

2 stops26h 47m

$478

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

jue. 5/1

5:45 am-1:15 pm

1 stop6h 30m

Santo Domingo Las Americas

lun. 5/12

7:00 am-6:26 pm

1 stop12h 26m

$493

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

dom. 5/4

5:09 am-3:12 pm

1 stop9h 03m

Santo Domingo Las Americas

dom. 5/11

12:15 pm-10:38 pm

1 stop11h 23m

$498

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

mié. 6/11

10:48 am-12:37 am

2 stops12h 49m

Santo Domingo Las Americas

mié. 6/18

6:00 am-6:44 pm

2 stops13h 44m

$519

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

lun. 5/12

7:58 pm-9:45 pm

2 stops24h 47m

Santo Domingo Las Americas

lun. 5/19

4:50 pm-1:50 pm

2 stops22h 00m

$535

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

mié. 6/18

7:20 pm-9:08 am

2 stops12h 48m

Santo Domingo Las Americas

dom. 6/22

11:49 am-10:20 am

2 stops23h 31m

$553

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

mié. 6/11

5:25 am-1:35 pm

1 stop7h 10m

Santo Domingo Las Americas

mié. 6/18

10:13 am-11:59 pm

1 stop14h 46m

$575

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

lun. 5/12

6:40 pm-2:10 pm

2 stops18h 30m

Santo Domingo Las Americas

mar. 5/27

1:10 pm-10:10 pm

1 stop10h 00m

$618

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

jue. 7/10

5:00 am-1:50 am

2 stops19h 50m

Santo Domingo Las Americas

sáb. 7/19

3:20 pm-11:32 pm

1 stop9h 12m

$899

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/26

Showing 1-10 of 16 results
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Best time to book a flight from Missouri to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Santo Domingo

What is the cheapest month to book a flight from Missouri to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Missouri to Santo Domingo (average of $362). Flying from Missouri to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SDQ?

Find hourly flight availability from Missouri to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 29, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Santo Domingo as you normally would.

Rainfall in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

Temperature in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated abril 29, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines and American Airlines from Missouri to Santo Domingo to help guide your decision. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,929 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Spirit Airlines
6.3
Okay
7,954 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santo Domingo from Missouri?

    Most people fly into Santo Domingo Las Americas (SDQ) if they book a flight to Santo Domingo from Missouri. Las Americas is conveniently located just 17.5 mi from Santo Domingo’s city center.

  • What are the cheapest airlines to fly from Missouri to Santo Domingo one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $210. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from Missouri to Santo Domingo for a low price.

  • Can I find deals for flights from Missouri to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Missouri to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Santo Domingo.

  • Can I find deals for business class flights from Missouri to Santo Domingo?

    Yes. Cheapflights offers flight deals from Missouri to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Santo Domingo (average of $362). Flying from Missouri to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missouri?

Book flights to Missouri if you plan to visit one of these locations
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Alternative routes for Missouri to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Santo Domingo

Discover the top 4 airlines that operate flights from Missouri to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$262Average$553FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$319Average$660FlexibilityNo cancel feeOn-time65%
FrontierCheapest$371Average$384FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$452Average$649FlexibilityNo cancel feeOn-time71%

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