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Santo Domingo

$108+ Cheap flights from Key Largo, FL to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — SDQ
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheapflights Tip: The best prices from Key Largo to Santo Domingo Las Americas are usually found in May or January, booked 83 days in advance, depart on a Tuesday or Sunday and return on a Thursday

Cheap flight deals from Key Largo to Santo Domingo

Keep the following information in mind while searching for Key Largo to Santo Domingo flight deals. Data was last updated April 17, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$248
(Mytrip)

One-way from

$108
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$344
Provider with most accurate pricing for Miami-Santo Domingo Las Americas flight deals.
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Provider most trusted by Cheapflights users for Miami-Santo Domingo Las Americas flights.
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From Key Largo to Santo Domingo Las Americas
Search Deals
One-way flight from Key Largo to Santo Domingo Las Americas
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Highest demand for flights based on searches. 8% potential increase in price ($33 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Key Largo to Santo Domingo

Cheapest flights from Key Largo to Santo Domingo
Explore the most affordable flight options available from Key Largo to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/162:09 pmMIA - SDQ
Nonstop2h 20mArajet
Tue 5/203:35 pmSDQ - MIA
Nonstop2h 20mArajet
Deal found 4/16$248
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/277:25 pmMIA - SDQ
Nonstop2h 20mMultiple Airlines
Thu 6/56:00 pmSDQ - MIA
Nonstop2h 00mMultiple Airlines
Deal found 4/16$280
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1212:05 pmMIA - SDQ
Nonstop2h 35mAmerican Airlines
Wed 8/2011:30 amSDQ - MIA
Nonstop2h 25mAmerican Airlines
Deal found 4/17$282
This Expedia deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/186:00 pmMIA - SDQ
Nonstop2h 00mSky High
Sun 4/202:30 pmSDQ - MIA
Nonstop2h 00mSky High
Deal found 4/17$301
This Copa Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/162:16 pmMIA - SDQ
1 stop7h 52mCopa Airlines
Fri 5/232:05 pmSDQ - MIA
1 stop8h 32mCopa Airlines
Deal found 4/16$309
This WorldTicket deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WorldTicket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/291:09 pmMIA - SDQ
Nonstop2h 20mWorldTicket
Mon 1/510:19 amSDQ - MIA
Nonstop2h 20mWorldTicket
Deal found 4/15$324
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/66:00 amMIA - SDQ
1 stop7h 15mDelta
Tue 5/202:41 pmSDQ - MIA
1 stop7h 10mDelta
Deal found 4/17$335
This FlightHub deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/37:25 pmMIA - SDQ
Nonstop2h 20mHahn Air
Fri 6/1310:19 amSDQ - MIA
Nonstop2h 20mHahn Air
Deal found 4/16$362
This Frontier deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/47:25 amMIA - SDQ
1 stop5h 05mFrontier
Fri 6/277:29 pmSDQ - MIA
Nonstop2h 27mFrontier
Deal found 4/16$385

Cheapflights Fare Finder

Customize your flight search to find flights from Key Largo to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Key Largo to Santo Domingo that are best for you.

Fly from

Key Largo

Fly to

Santo Domingo

Route

Depart

Return

Price

MiamiSanto Domingo

MIA - SDQ

MIASDQ

Miami

Fri 5/16

2:09 pm-4:29 pm

Nonstop2h 20m

Santo Domingo Las Americas

Tue 5/20

3:35 pm-5:55 pm

Nonstop2h 20m

$248

MiamiSanto Domingo

MIA - SDQ

MIASDQ

Miami

Tue 5/27

7:25 pm-9:45 pm

Nonstop2h 20m

Santo Domingo Las Americas

Thu 6/5

6:00 pm-8:00 pm

Nonstop2h 00m

$280

MiamiSanto Domingo

MIA - SDQ

MIASDQ

Miami

Tue 8/12

12:05 pm-2:40 pm

Nonstop2h 35m

Santo Domingo Las Americas

Wed 8/20

11:30 am-1:55 pm

Nonstop2h 25m

$282

MiamiSanto Domingo

MIA - SDQ

MIASDQ

Miami

Fri 7/25

3:40 pm-6:15 pm

Nonstop2h 35m

Santo Domingo Las Americas

Mon 7/28

7:30 pm-9:54 pm

Nonstop2h 24m

$290

MiamiSanto Domingo

MIA - SDQ

MIASDQ

Miami

Fri 5/16

6:01 am-10:08 pm

1 stop16h 07m

Santo Domingo Las Americas

Tue 5/20

2:05 pm-10:37 pm

1 stop8h 32m

$309

MiamiSanto Domingo

MIA - SDQ

MIASDQ

Miami

Tue 5/6

6:00 am-1:15 pm

1 stop7h 15m

Santo Domingo Las Americas

Tue 5/20

2:41 pm-9:51 pm

1 stop7h 10m

$335

MiamiSanto Domingo

MIA - SDQ

MIASDQ

Miami

Wed 7/9

2:09 pm-4:29 pm

Nonstop2h 20m

Santo Domingo Las Americas

Mon 7/14

10:19 am-12:39 pm

Nonstop2h 20m

$344

MiamiSanto Domingo

MIA - SDQ

MIASDQ

Miami

Fri 5/2

6:00 pm-8:00 pm

Nonstop2h 00m

Santo Domingo Las Americas

Mon 5/5

10:00 am-12:00 pm

Nonstop2h 00m

$350

MiamiSanto Domingo

MIA - SDQ

MIASDQ

Miami

Tue 6/3

7:25 pm-9:45 pm

Nonstop2h 20m

Santo Domingo Las Americas

Fri 6/13

10:19 am-12:39 pm

Nonstop2h 20m

$362

MiamiSanto Domingo

MIA - SDQ

MIASDQ

Miami

Wed 5/28

2:09 pm-4:29 pm

Nonstop2h 20m

$108

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 23 results
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Best time to book a flight from Key Largo to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Santo Domingo

How far ahead should I book a flight from Key Largo to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Key Largo to Santo Domingo. Price data was last updated on April 11, 2025.

The best time to book flights from Key Largo to Santo Domingo is 83 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Key Largo to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Key Largo to Santo Domingo (average of $362). Flying from Key Largo to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to SDQ?

Find hourly flight availability from Key Largo to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

When flying from Key Largo to Santo Domingo, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Key Largo to Santo Domingo?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to Santo Domingo. Price data was last updated on April 7, 2024.

Travelers seeking maximum savings on their Key Largo to Santo Domingo flight should consider departing on Monday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Key Largo to Santo Domingo

Explore weekly flight availability from Key Largo to Santo Domingo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 17, 2025.

The most flights from KE9 to SDQ are scheduled on a Monday (9 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (7 on average).

Rainfall in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

Temperature in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated April 17, 2025.
Read through reviews of airlines operating flights from Key Largo to Santo Domingo, such as Delta, Copa Airlines and JetBlue. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,916 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
Delta
8.0
Very good
7,916 reviews
Delta
8.0
Very good
7,916 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
Copa Airlines
7.6
Good
1,409 reviews
Delta
8.0
Very good
7,916 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
JetBlue
7.3
Good
2,926 reviews
Delta
8.0
Very good
7,916 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,916 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
Avianca
6.7
Okay
2,316 reviews
Delta
8.0
Very good
7,916 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santo Domingo from Key Largo?

    Santo Domingo Las Americas (SDQ), located 17.5 mi from the city center, is the airport you fly into when you book flights from Key Largo to Santo Domingo. 8 airlines have flights to Las Americas from Key Largo on a regular basis. Booking flights from Key Largo to Santo Domingo Las Americas should not be difficult; the airport handles an average of 8 inbound flights from Key Largo per day.

  • How popular is this Key Largo to Santo Domingo flight route?

    This flight path from Key Largo to Santo Domingo Las Americas was viewed by 29 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Key Largo to Santo Domingo one-way?

    The cheapest airlines for a one-way flight from Key Largo to Santo Domingo are Arajet ($108), Frontier ($134), and Sky High ($145).

  • What are the most reliable airlines from Key Largo to Santo Domingo?

    The top 3 most reliable airlines when flying from Key Largo to Santo Domingo are Arajet (100%), American Airlines (71%) and British Airways (63%).

  • What are the cheapest flights from Key Largo to Santo Domingo?

    On average you can expect to pay $237 for a flight from Key Largo to Santo Domingo. The cheapest flight overall is $99 while the most popular route, (Miami - Santo Domingo Las Americas) is currently priced at $221.

  • Can I find deals for flights from Key Largo to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Key Largo to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Santo Domingo.

  • Can I find deals for business class flights from Key Largo to Santo Domingo?

    Yes. Cheapflights offers flight deals from Key Largo to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Key Largo to Santo Domingo (average of $362). Flying from Key Largo to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 8 airlines flying from Key Largo to Santo Domingo

Discover the top 8 airlines that operate flights from Key Largo to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$83Average$287FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$124Average$271FlexibilityNo cancel feeOn-time65%
Copa AirlinesCheapest$152Average$341FlexibilityNo cancel feeOn-time70%
JetBlueCheapest$173Average$374FlexibilityNo cancel feeOn-time62%
Sky HighCheapest$200Average$411FlexibilityNo cancel feeOn-timeN/A
ArajetCheapest$205Average$288FlexibilityNo cancel feeOn-timeN/A
Hahn AirCheapest$261Average$537FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$279Average$399FlexibilityNo cancel feeOn-time71%

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