What are the cheapest airlines flying from St. Louis to Santiago de los Caballeros round-trip?

According to our current data, Delta ($589), United Airlines ($709), and American Airlines ($894) offers the cheapest pricing from St. Louis to Santiago de los Caballeros. Delta is currently priced 14% below the average price you’ll pay for this route.

What is the cheapest day to fly from St. Louis to Santiago de los Caballeros?

Travelers seeking maximum savings on their St. Louis to Santiago de los Caballeros flight should consider departing on Tuesday mornings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

What is the cheapest day to fly round-trip from St. Louis to Santiago de los Caballeros?

Departing on a Monday is a good option for securing a great price. You can expect to save up to 52% when planning your travel around this day of the week.

What is the cheapest month to fly from St. Louis to Santiago de los Caballeros?

Our data shows that May tends to be the cheapest month to fly to Santiago de los Caballeros from St. Louis. Users have commonly found prices around $686 for the month, but tickets can be as low as $443. Due to multiple factors, prepare for potentially higher prices in December.

What is the cheapest time of day to fly from STL to STI?

One of the essential ways to save on airfare from St. Louis to Santiago de los Caballeros is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 23% on airfare.

Most accurate provider : When it comes to deals on St. Louis-Santiago de los Caballeros flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Santiago de los Caballeros flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Santiago de los Caballeros flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on St. Louis-Santiago de los Caballeros flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

How can I find direct flights from St. Louis to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Santiago de los Caballeros.

Can I find deals for business class flights from St. Louis to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from St. Louis to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$341+ Flights from St. Louis to Santiago de los Caballeros

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from St. Louis to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from St. Louis to Santiago de los Caballeros

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$589 (Delta)
One-way from	$341 (Delta)
Popular in	December
Cheapest in	May
Average price	$559

Provider with most accurate pricing for Lambert-St Louis-Santiago de los Caballeros flight deals.

Search Deals

Provider most trusted by Cheapflights users for Lambert-St Louis-Santiago de los Caballeros flights.

Search Deals

From Lambert-St Louis to Santiago de los Caballeros

Search Deals

One-way flight from Lambert-St Louis to Santiago de los Caballeros

Search Deals

Highest demand for flights based on searches. 14% potential increase in price ($113 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

Search Deals

Find flight deals from St. Louis to Santiago de los Caballeros

Cheapest flights from St. Louis to Santiago de los Caballeros
Explore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2025.

Sat 5/312:47 pmSTL - STI

2 stops10h 40mDelta

Sat 5/106:11 amSTI - STL

2 stops15h 28mDelta

Deal found 4/9

$589

Sat 5/38:00 amSTL - STI

2 stops16h 46mUnited Airlines

Sat 5/102:07 pmSTI - STL

1 stop10h 42mUnited Airlines

Deal found 4/9

$709

Sat 5/36:09 pmSTL - STI

1 stop19h 17mAmerican Airlines

Sat 5/103:25 pmSTI - STL

1 stop7h 54mAmerican Airlines

Deal found 4/9

$894

Best flights from St. Louis to Santiago de los Caballeros
Discover carefully curated flight deals from St. Louis to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2025.

Sat 5/312:47 pmSTL - STI

2 stops10h 40mDelta

Sat 5/106:11 amSTI - STL

2 stops15h 28mDelta

Deal found 4/9

$589

Sat 5/38:00 amSTL - STI

2 stops16h 46mUnited Airlines

Sat 5/102:07 pmSTI - STL

1 stop10h 42mUnited Airlines

Deal found 4/9

$709

Sat 5/36:09 pmSTL - STI

1 stop19h 17mAmerican Airlines

Sat 5/103:25 pmSTI - STL

1 stop7h 54mAmerican Airlines

Deal found 4/9

$894

Last-minute flights from St. Louis to Santiago de los Caballeros
Discover last-minute flight deals from St. Louis to Santiago de los Caballeros. Data last updated April 10, 2025 and is based on user searches.

Sat 5/312:47 pmSTL - STI

2 stops10h 40mDelta

Sat 5/106:11 amSTI - STL

2 stops15h 28mDelta

Deal found 4/9

$589

Sat 5/38:00 amSTL - STI

2 stops16h 46mUnited Airlines

Sat 5/102:07 pmSTI - STL

1 stop10h 42mUnited Airlines

Deal found 4/9

$709

Sat 5/36:09 pmSTL - STI

1 stop19h 17mAmerican Airlines

Sat 5/103:25 pmSTI - STL

1 stop7h 54mAmerican Airlines

Deal found 4/9

$894

One-way flights from St. Louis to Santiago de los Caballeros
Search for one-way flight options from St. Louis to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated April 10, 2025.

Mon 4/147:10 amSTL - STI

2 stops16h 17mDelta

Deal found 4/8

$341

Sat 4/127:04 pmSTL - STI

2 stops18h 22mAmerican Airlines

Deal found 4/8

$347

Sat 4/129:50 amSTL - STI

3 stops27h 56mMultiple Airlines

Deal found 4/8

$423

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Sat 5/3

12:47 pm-12:27 am

2 stops10h 40m

Santiago de los Caballeros

Sat 5/10

6:11 am-8:39 pm

2 stops15h 28m

$589

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Sat 5/3

8:00 am-1:46 am

2 stops16h 46m

Santiago de los Caballeros

Sat 5/10

2:07 pm-11:49 pm

1 stop10h 42m

$709

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Sat 5/3

6:09 pm-2:26 pm

1 stop19h 17m

Santiago de los Caballeros

Sat 5/10

3:25 pm-10:19 pm

1 stop7h 54m

$894

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Mon 4/14

7:10 am-12:27 am

2 stops16h 17m

$341

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Sat 4/12

7:04 pm-2:26 pm

2 stops18h 22m

$347

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

Sat 4/12

9:50 am-2:46 pm

3 stops27h 56m

$423

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/8

Compare providers for flights from St. Louis to Santiago de los Caballeros

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santiago de los Caballeros in April.

Provider	Price Accuracy	Trust Score*
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy3 stars	Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on St. Louis-Santiago de los Caballeros flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Santiago de los Caballeros flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Santiago de los Caballeros flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on St. Louis-Santiago de los Caballeros flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Santiago de los Caballeros

What is the cheapest month to book a flight from St. Louis to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from St. Louis to Santiago de los Caballeros (average of $347). Flying from St. Louis to Santiago de los Caballeros in July is currently the most expensive (average of $631). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Santiago de los Caballeros by month

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

Temperature in Santiago de los Caballeros by month

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Santiago de los Caballeros

Delta

8.0

Very good

7,907 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,907 reviews

Delta

8.0

Very good

7,907 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

8,634 reviews

Delta

8.0

Very good

7,907 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,907 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What are the cheapest airlines flying from St. Louis to Santiago de los Caballeros round-trip?
According to our current data, Delta ($589), United Airlines ($709), and American Airlines ($894) offers the cheapest pricing from St. Louis to Santiago de los Caballeros. Delta is currently priced 14% below the average price you’ll pay for this route.
Can I find deals for flights from St. Louis to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on St. Louis to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Santiago de los Caballeros.
Can I find deals for business class flights from St. Louis to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from St. Louis to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from St. Louis to Santiago de los Caballeros?
Currently, May is the cheapest month in which you can book a flight from St. Louis to Santiago de los Caballeros (average of $347). Flying from St. Louis to Santiago de los Caballeros in July is currently the most expensive (average of $631). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top airline flying from St. Louis to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$466	Average$793	FlexibilityNo cancel fee	On-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$341+ Cheap flights from St. Louis (STL) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/14. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from St. Louis to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from St. Louis to Santiago de los Caballeros

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from St. Louis to Santiago de los Caballeros

Cheapest flights from St. Louis to Santiago de los CaballerosExplore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2025.

Explore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Santiago de los Caballeros that are best for you.

Compare providers for flights from St. Louis to Santiago de los Caballeros

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santiago de los Caballeros in April.

Best time to book a flight from St. Louis to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from St. Louis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Santiago de los Caballeros

What is the cheapest month to book a flight from St. Louis to Santiago de los Caballeros?

Rainfall in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average rainfall totals by month.

Temperature in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average temperature totals by month.

Reviews of airlines servicing Santiago de los Caballeros

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from St. Louis to Santiago de los Caballeros round-trip?

Can I find deals for flights from St. Louis to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from St. Louis to Santiago de los Caballeros?

Can I find deals for business class flights from St. Louis to Santiago de los Caballeros?

What is the cheapest month to book a flight from St. Louis to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from St. Louis to Santiago de los Caballeros

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from St. Louis to Santiago de los Caballeros
Explore the most affordable flight options available from St. Louis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2025.