What are the cheapest airlines to fly from San Francisco to Santiago de los Caballeros one-way?

$271 is the cheapest one-way deal found within the past few days, from JetBlue. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $356 and $379, respectively.

What is the cheapest day to fly from San Francisco to Santiago de los Caballeros?

Travelers seeking maximum savings on their San Francisco to Santiago de los Caballeros flight should consider departing on Monday mornings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

What are the most popular airlines that fly from San Francisco to Santiago de los Caballeros?

When booking a flight from San Francisco to Santiago de los Caballeros, you may want to consider flying on American Airlines, JetBlue or Delta as they are the most popular for this route.

What is the cheapest day to fly round-trip from San Francisco to Santiago de los Caballeros?

Leaving on a Sunday is a viable option for saving on travel. Heavily demanded days of the week can typically drive up the prices you see. Booking your travel for a less competitive day can save up to 77% on the overall cost on flights from San Francisco to Santiago de los Caballeros.

What is the cheapest month to fly from San Francisco to Santiago de los Caballeros?

January can be a great time to fly to Santiago de los Caballeros from San Francisco with a flight ticket averaging about $795. Cheapflights users have found deals in the month of January for as cheap as $480. The most expensive prices can be found in the month of February.

Most accurate provider : When it comes to deals on San Francisco-Santiago de los Caballeros flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Santiago de los Caballeros flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Santiago de los Caballeros flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on San Francisco-Santiago de los Caballeros flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

How can I find direct flights from San Francisco to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santiago de los Caballeros.

Can I find deals for business class flights from San Francisco to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from San Francisco to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$271+ Flights from San Francisco to Santiago de los Caballeros

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Francisco to Santiago de los Caballeros

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$530 (JetBlue)
One-way from	$271 (JetBlue)
Popular in	February
Cheapest in	January
Average price	$596

Provider with most accurate pricing for San Francisco-Santiago de los Caballeros flight deals.

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Provider most trusted by Cheapflights users for San Francisco-Santiago de los Caballeros flights.

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From San Francisco to Santiago de los Caballeros

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One-way flight from San Francisco to Santiago de los Caballeros

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High demand for flights, 0% potential price rise

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Cheapest flight prices on average. 4% potential price decrease ($38 potential savings vs. average RT price).

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Average for round-trip flights in March 2025

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Find flight deals from San Francisco to Santiago de los Caballeros

Cheapest flights from San Francisco to Santiago de los Caballeros
Explore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

Fri 4/258:10 pmSFO - STI

1 stop12h 02mJetBlue

Sat 5/108:35 pmSTI - SFO

1 stop16h 25mJetBlue

Deal found 3/26

$530

Fri 4/2511:37 pmSFO - STI

1 stop11h 37mAmerican Airlines

Sat 5/103:25 pmSTI - SFO

2 stops21h 05mAmerican Airlines

Deal found 3/26

$854

Fri 4/258:20 amSFO - STI

2 stops31h 30mMultiple Airlines

Sat 5/101:30 pmSTI - SFO

3 stops25h 00mMultiple Airlines

Deal found 3/26

$3,117

Best flights from San Francisco to Santiago de los Caballeros
Discover carefully curated flight deals from San Francisco to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 28, 2025.

Fri 4/258:10 pmSFO - STI

1 stop12h 02mJetBlue

Sat 5/108:35 pmSTI - SFO

1 stop16h 25mJetBlue

Deal found 3/26

$530

Fri 4/2511:37 pmSFO - STI

1 stop11h 37mAmerican Airlines

Sat 5/103:25 pmSTI - SFO

2 stops21h 05mAmerican Airlines

Deal found 3/26

$854

Fri 4/258:20 amSFO - STI

2 stops31h 30mMultiple Airlines

Sat 5/101:30 pmSTI - SFO

3 stops25h 00mMultiple Airlines

Deal found 3/26

$3,117

Last-minute flights from San Francisco to Santiago de los Caballeros
Discover last-minute flight deals from San Francisco to Santiago de los Caballeros. Data last updated March 28, 2025 and is based on user searches.

Fri 4/258:10 pmSFO - STI

1 stop12h 02mJetBlue

Sat 5/108:35 pmSTI - SFO

1 stop16h 25mJetBlue

Deal found 3/26

$530

Fri 4/2511:37 pmSFO - STI

1 stop11h 37mAmerican Airlines

Sat 5/103:25 pmSTI - SFO

2 stops21h 05mAmerican Airlines

Deal found 3/26

$854

Fri 4/258:20 amSFO - STI

2 stops31h 30mMultiple Airlines

Sat 5/101:30 pmSTI - SFO

3 stops25h 00mMultiple Airlines

Deal found 3/26

$3,117

One-way flights from San Francisco to Santiago de los Caballeros
Search for one-way flight options from San Francisco to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated March 28, 2025.

Tue 5/206:00 amSFO - STI

1 stop15h 44mJetBlue

Deal found 3/27

$271

Tue 9/29:00 amSFO - STI

1 stop13h 12mDelta

Deal found 3/27

$356

Sun 7/1311:20 pmSFO - STI

1 stop12h 52mUnited Airlines

Deal found 3/27

$379

Sun 7/136:45 pmSFO - STI

2 stops14h 39mAmerican Airlines

Deal found 3/27

$401

Tue 5/2011:50 pmSFO - STI

3 stops35h 58mMultiple Airlines

Deal found 3/27

$496

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Fri 4/25

8:10 pm-11:12 am

1 stop12h 02m

Santiago de los Caballeros

Sat 5/10

8:35 pm-10:00 am

1 stop16h 25m

$530

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Fri 4/25

11:37 pm-2:14 pm

1 stop11h 37m

Santiago de los Caballeros

Sat 5/10

3:25 pm-9:30 am

2 stops21h 05m

$854

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Fri 4/25

8:20 am-6:50 pm

2 stops31h 30m

Santiago de los Caballeros

Sat 5/10

1:30 pm-11:30 am

3 stops25h 00m

$3,117

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Tue 5/20

6:00 am-12:44 am

1 stop15h 44m

$271

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Tue 9/2

9:00 am-1:12 am

1 stop13h 12m

$356

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Sun 7/13

11:20 pm-3:12 pm

1 stop12h 52m

$379

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Sun 7/13

6:45 pm-12:24 pm

2 stops14h 39m

$401

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Tue 5/20

11:50 pm-2:48 pm

3 stops35h 58m

$496

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Compare providers for flights from San Francisco to Santiago de los Caballeros

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santiago de los Caballeros in March.

Provider	Price Accuracy	Trust Score*
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy3 stars	Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on San Francisco-Santiago de los Caballeros flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Santiago de los Caballeros flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Santiago de los Caballeros flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on San Francisco-Santiago de los Caballeros flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from San Francisco with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santiago de los Caballeros

What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from San Francisco to Santiago de los Caballeros (average of $347). Flying from San Francisco to Santiago de los Caballeros in July is currently the most expensive (average of $631). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to STI?

It’s typically best to fly out from San Francisco to Santiago de los Caballeros in the afternoon. Doing so could potentially save you 33% on the flight price compared to flying in the evening, which is usually more expensive.

Rainfall in Santiago de los Caballeros by month

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

Temperature in Santiago de los Caballeros by month

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Santiago de los Caballeros

Delta

8.0

Very good

7,897 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,897 reviews

Delta

8.0

Very good

7,897 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

8,603 reviews

Delta

8.0

Very good

7,897 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

JetBlue

7.3

Good

2,923 reviews

Delta

8.0

Very good

7,897 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,897 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What are the cheapest airlines flying from San Francisco to Santiago de los Caballeros round-trip?
JetBlue, at $530, was found to be the cheapest airline from San Francisco to Santiago de los Caballeros. An alternate airline flying to your destination would be American Airlines. These flights start at 33% lower than the current average price 3 months from now.
What are the cheapest airlines to fly from San Francisco to Santiago de los Caballeros one-way?
$271 is the cheapest one-way deal found within the past few days, from JetBlue. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $356 and $379, respectively.
Can I find deals for flights from San Francisco to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on San Francisco to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from San Francisco to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santiago de los Caballeros.
Can I find deals for business class flights from San Francisco to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from San Francisco to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?
Currently, May is the cheapest month in which you can book a flight from San Francisco to Santiago de los Caballeros (average of $347). Flying from San Francisco to Santiago de los Caballeros in July is currently the most expensive (average of $631). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from San Francisco to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
JetBlue	Cheapest$463	Average$568	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$472	Average$634	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$473	Average$742	FlexibilityNo cancel fee	On-time71%

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$271+ Cheap flights from San Francisco (SFO) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from San Francisco to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from San Francisco to Santiago de los Caballeros

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from San Francisco to Santiago de los Caballeros

Cheapest flights from San Francisco to Santiago de los CaballerosExplore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

Explore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Santiago de los Caballeros that are best for you.

Compare providers for flights from San Francisco to Santiago de los Caballeros

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santiago de los Caballeros in March.

Best time to book a flight from San Francisco to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from San Francisco with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santiago de los Caballeros

What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?

What is the cheapest time of day to fly from SFO to STI?

Find hourly flight availability from San Francisco to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

Rainfall in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average rainfall totals by month.

Temperature in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average temperature totals by month.

Reviews of airlines servicing Santiago de los Caballeros

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from San Francisco to Santiago de los Caballeros round-trip?

What are the cheapest airlines to fly from San Francisco to Santiago de los Caballeros one-way?

Can I find deals for flights from San Francisco to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from San Francisco to Santiago de los Caballeros?

Can I find deals for business class flights from San Francisco to Santiago de los Caballeros?

What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Francisco to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from San Francisco to Santiago de los Caballeros

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Cheapest flights from San Francisco to Santiago de los Caballeros
Explore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.