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Santiago de los Caballeros

$386+ Cheap flights from Panama City (PTY) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — STI
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Find cheap flights from Panama City to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
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3. Compare prices and book
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Cheapflights Tip: The best prices from Panama City Tocumen Intl to Santiago de los Caballeros are usually found in May or June, booked 62 days in advance, depart on a Tuesday or Wednesday and return on a Monday

Cheap flight deals from Panama City to Santiago de los Caballeros

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$1,197
(American Airlines)

One-way from

$491
(Kiwi.com)

Popular in

April

Cheapest in

May

Average price

$1,043

Good one-way deal

$464 or less
Provider with most accurate pricing for Panama City Tocumen Intl-Santiago de los Caballeros flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Santiago de los Caballeros flights.
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From Panama City Tocumen Intl to Santiago de los Caballeros
Search Deals
One-way flight from Panama City Tocumen Intl to Santiago de los Caballeros
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($239 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($45 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Price to beat on a one-way flight from Panama City Tocumen Intl to Santiago de los Caballeros.
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Find flight deals from Panama City to Santiago de los Caballeros

Cheapest flights from Panama City to Santiago de los Caballeros
Explore the most affordable flight options available from Panama City to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/201:20 pmPTY - STI
1 stop24h 40mAmerican Airlines
Tue 5/273:50 pmSTI - PTY
1 stop21h 29mAmerican Airlines
Deal found 3/27$1,197
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/262:20 pmPTY - STI
2 stops20h 39mDelta
Sat 5/36:10 amSTI - PTY
2 stops14h 20mDelta
Deal found 3/27$1,256
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/177:55 amPTY - STI
2 stops16h 51mUnited Airlines
Fri 7/252:07 pmSTI - PTY
2 stops25h 07mUnited Airlines
Deal found 3/27$1,723
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/201:20 pmPTY - STI
1 stop24h 40mMultiple Airlines
Tue 5/273:50 pmSTI - PTY
2 stops67h 42mMultiple Airlines
Deal found 3/27$3,301

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Panama City to Santiago de los Caballeros that are best for you.

Fly from

Panama City

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

Panama CitySantiago de los Caballeros

PTY - STI

PTYSTI

Panama City Tocumen Intl

Tue 5/20

1:20 pm-3:00 pm

1 stop24h 40m

Santiago de los Caballeros

Tue 5/27

3:50 pm-12:19 pm

1 stop21h 29m

$1,197

Panama CitySantiago de los Caballeros

PTY - STI

PTYSTI

Panama City Tocumen Intl

Sat 4/26

2:20 pm-11:59 am

2 stops20h 39m

Santiago de los Caballeros

Sat 5/3

6:10 am-7:30 pm

2 stops14h 20m

$1,256

Panama CitySantiago de los Caballeros

PTY - STI

PTYSTI

Panama City Tocumen Intl

Thu 7/17

7:55 am-1:46 am

2 stops16h 51m

Santiago de los Caballeros

Fri 7/25

2:07 pm-2:14 pm

2 stops25h 07m

$1,723

Panama CitySantiago de los Caballeros

PTY - STI

PTYSTI

Panama City Tocumen Intl

Tue 5/20

1:20 pm-3:00 pm

1 stop24h 40m

Santiago de los Caballeros

Tue 5/27

3:50 pm-10:32 am

2 stops67h 42m

$3,301

Panama CitySantiago de los Caballeros

PTY - STI

PTYSTI

Panama City Tocumen Intl

Sat 4/26

9:34 am-2:46 pm

2 stops28h 12m

$386

Panama CitySantiago de los Caballeros

PTY - STI

PTYSTI

Panama City Tocumen Intl

Fri 4/25

1:15 pm-2:26 pm

1 stop48h 11m

$517

Panama CitySantiago de los Caballeros

PTY - STI

PTYSTI

Panama City Tocumen Intl

Fri 4/25

2:20 pm-11:59 am

2 stops20h 39m

$768

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Compare providers for flights from Panama City to Santiago de los Caballeros

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Santiago de los Caballeros in March.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Santiago de los Caballeros flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Santiago de los Caballeros flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Santiago de los Caballeros flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Santiago de los Caballeros flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Santiago de los Caballeros

How far ahead should I book a flight from Panama City to Santiago de los Caballeros?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Santiago de los Caballeros. Price data was last updated on March 21, 2025.

The price you pay for your flight from Panama City to Santiago de los Caballeros may vary depending on when you book. For the best chance of a lower fare, look to book 62 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Panama City to Santiago de los Caballeros (average of $347). Flying from Panama City to Santiago de los Caballeros in July is currently the most expensive (average of $631). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

Temperature in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Santiago de los Caballeros

Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated March 28, 2025.
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kade,Sep 2023

LHR - SLC

It was weird that we had to check after security and go to a corral which had no bathroom or other services about an hour before boarding. Had to check out of the corral to leave and check back in.
Delta
8.0
Very good
7,896 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kade,Sep 2023

LHR - SLC

It was weird that we had to check after security and go to a corral which had no bathroom or other services about an hour before boarding. Had to check out of the corral to leave and check back in.
United Airlines
7.4
Good
8,603 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kade,Sep 2023

LHR - SLC

It was weird that we had to check after security and go to a corral which had no bathroom or other services about an hour before boarding. Had to check out of the corral to leave and check back in.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Overall

8.0

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kade,Sep 2023

LHR - SLC

It was weird that we had to check after security and go to a corral which had no bathroom or other services about an hour before boarding. Had to check out of the corral to leave and check back in.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City to Santiago de los Caballeros round-trip?

    Our cheapest airline available from Panama City to Santiago de los Caballeros is American Airlines. Our recent data shows that you can find tickets from as low as $1,197 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $1,256 and $1,723 round-trip.

  • What are the cheapest flights from Panama City to Santiago de los Caballeros?

    While on average a flight from Panama City to Santiago de los Caballeros is generally $464, our data shows the cheapest flight currently is $464. When looking at the most popular route, (Panama City Tocumen Intl - Santiago de los Caballeros), you can expect to pay $1,299 for that flight.

  • Can I find deals for flights from Panama City to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on Panama City to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Santiago de los Caballeros.

  • Can I find deals for business class flights from Panama City to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from Panama City to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Santiago de los Caballeros?

    Currently, May is the cheapest month in which you can book a flight from Panama City to Santiago de los Caballeros (average of $347). Flying from Panama City to Santiago de los Caballeros in July is currently the most expensive (average of $631). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama City to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Punta Cana flights
Panama City to Santo Domingo flights

Top airline flying from Panama City to Santiago de los Caballeros

Discover the top airline that operate flights from Panama City to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$313Average$344FlexibilityNo cancel feeOn-time70%
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