What are the cheapest airlines to fly from Irvine to Santiago de los Caballeros one-way?

To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $202. Delta flights start at $235 while deals on Frontier start at $255 one-way.

What is the cheapest day to fly from Irvine to Santiago de los Caballeros?

Travelers seeking maximum savings on their Irvine to Santiago de los Caballeros flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

What are the most popular airlines that fly from Irvine to Santiago de los Caballeros?

Consider American Airlines, JetBlue or Copa Airlines when booking your flight. These represent the most popular airlines when flying from Irvine to Santiago de los Caballeros.

How far in advance should I book a flight from Irvine to Santiago de los Caballeros?

To save on the cost of your flight from Irvine to Santiago de los Caballeros, book at least 23 days before your planned departure. Booking around this time can save you about 35% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $409 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $809.

What is the cheapest month to fly from Irvine to Santiago de los Caballeros?

Due to multiple factors, expect to potentially pay more when booking in December. For low rates, September can be a great choice for travel to Santiago de los Caballeros. Flights to Santiago de los Caballeros from Irvine in September are about $636 on average during September, but can be found for as low as $381.

What airport do you fly into for flights to Santiago de los Caballeros from Irvine?

Most people fly into Santiago de los Caballeros (STI) if they book a flight to Santiago de los Caballeros from Irvine. On average, Santiago has 0 inbound flights from Irvine per day from 4 airlines. Santiago de los Caballeros is conveniently located just 6.8 mi from Santiago de los Caballeros’s city center.

How can I find direct flights from Irvine to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Santiago de los Caballeros.

Can I find deals for business class flights from Irvine to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from Irvine to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$202+ Flights from Irvine to Santiago de los Caballeros

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Cheapflights Tip: The best prices from Irvine to Santiago de los Caballeros are usually found in September or October, booked 23 days in advance, depart on a Wednesday or Tuesday and return on a Monday

Cheap flight deals from Irvine to Santiago de los Caballeros

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$493 (Delta)
One-way from	$202 (Mytrip)
Popular in	December
Cheapest in	September
Average price	$537

Provider with most accurate pricing for Los Angeles-Santiago de los Caballeros flight deals.

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Provider most trusted by Cheapflights users for Los Angeles-Santiago de los Caballeros flights.

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From Irvine to Santiago de los Caballeros

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One-way flight from Irvine to Santiago de los Caballeros

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Highest demand for flights based on searches. 21% potential increase in price ($176 potential increase over avg. RT price).

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Cheapest flight prices on average. 8% potential price decrease ($50 potential savings vs. average RT price).

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Average for round-trip flights in April 2025

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Find flight deals from Irvine to Santiago de los Caballeros

Cheapest flights from Irvine to Santiago de los Caballeros
Explore the most affordable flight options available from Irvine to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

Tue 9/166:00 amLAX - STI

1 stop10h 54mDelta

Fri 9/261:53 pmSTI - LAX

1 stop12h 31mDelta

Deal found 4/22

$493

Sat 6/146:52 pmLAX - STI

2 stops12h 37mSpirit Airlines

Wed 6/1811:29 amSTI - LAX

2 stops22h 25mSpirit Airlines

Deal found 4/23

$526

Tue 9/163:25 pmLAX - STI

1 stop15h 25mJetBlue

Mon 9/221:50 amSTI - LAX

1 stop13h 12mJetBlue

Deal found 4/22

$559

Tue 7/158:00 amLAX - STI

1 stop10h 10mAmerican Airlines

Fri 7/257:04 amSTI - LAX

1 stop18h 28mAmerican Airlines

Deal found 4/23

$575

Best flights from Irvine to Santiago de los Caballeros
Discover carefully curated flight deals from Irvine to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2025.

Wed 5/146:00 amLAX - STI

1 stop15h 14mDelta

Fri 5/166:11 amSTI - LAX

1 stop15h 04mDelta

Deal found 4/22

$493

Sat 6/146:52 pmLAX - STI

2 stops12h 37mSpirit Airlines

Wed 6/1811:29 amSTI - LAX

2 stops22h 25mSpirit Airlines

Deal found 4/23

$526

Tue 7/158:00 amLAX - STI

1 stop10h 10mAmerican Airlines

Fri 7/257:04 amSTI - LAX

1 stop18h 28mAmerican Airlines

Deal found 4/23

$575

Wed 6/1111:15 amLAX - STI

1 stop10h 31mJetBlue

Mon 6/2310:38 pmSTI - LAX

1 stop15h 23mJetBlue

Deal found 4/23

$661

Last-minute flights from Irvine to Santiago de los Caballeros
Discover last-minute flight deals from Irvine to Santiago de los Caballeros. Data last updated April 24, 2025 and is based on user searches.

Wed 5/710:30 amLAX - STI

2 stops25h 18mSpirit Airlines

Sun 5/113:53 pmSTI - LAX

2 stops20h 42mSpirit Airlines

Deal found 4/22

$589

Wed 5/711:15 amLAX - STI

1 stop12h 32mJetBlue

Sat 5/103:45 amSTI - LAX

1 stop12h 05mJetBlue

Deal found 4/22

$661

Wed 5/76:57 pmLAX - STI

2 stops17h 03mAmerican Airlines

Sun 5/113:50 pmSTI - LAX

1 stop19h 53mAmerican Airlines

Deal found 4/22

$664

Wed 5/146:00 amLAX - STI

1 stop15h 14mDelta

Fri 5/166:11 amSTI - LAX

1 stop15h 04mDelta

Deal found 4/22

$493

One-way flights from Irvine to Santiago de los Caballeros
Search for one-way flight options from Irvine to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated April 24, 2025.

Mon 5/126:52 pmLAX - STI

2 stops16h 56mSpirit Airlines

Deal found 4/22

$202

Tue 5/139:15 pmLAX - STI

1 stop11h 50mDelta

Deal found 4/22

$235

Sat 5/1711:10 pmLAX - STI

2 stops15h 23mMultiple Airlines

Deal found 4/22

$245

Sun 5/114:59 pmLAX - STI

2 stops21h 34mFrontier

Deal found 4/22

$255

Thu 5/153:20 pmLAX - STI

1 stop14h 19mJetBlue

Deal found 4/22

$268

Mon 6/27:30 pmLAX - STI

2 stops14h 27mUnited Airlines

Deal found 4/22

$1,414

Cheapflights Fare Finder

Use the filters below to find and compare flights from Irvine to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Tue 9/16

6:00 am-7:54 pm

1 stop10h 54m

Santiago de los Caballeros

Fri 9/26

1:53 pm-11:24 pm

1 stop12h 31m

$493

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Sat 6/14

6:52 pm-10:29 am

2 stops12h 37m

Santiago de los Caballeros

Wed 6/18

11:29 am-6:54 am

2 stops22h 25m

$526

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Tue 9/16

3:25 pm-9:50 am

1 stop15h 25m

Santiago de los Caballeros

Mon 9/22

1:50 am-12:02 pm

1 stop13h 12m

$559

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Tue 7/15

8:00 am-9:10 pm

1 stop10h 10m

Santiago de los Caballeros

Fri 7/25

7:04 am-10:32 pm

1 stop18h 28m

$575

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Mon 5/12

6:52 pm-2:48 pm

2 stops16h 56m

$202

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Tue 5/13

7:30 am-12:14 am

2 stops13h 44m

$235

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Sat 5/17

11:10 pm-5:33 pm

2 stops15h 23m

$245

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Sun 5/11

4:59 pm-5:33 pm

2 stops21h 34m

$255

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Thu 5/15

3:20 pm-8:39 am

1 stop14h 19m

$268

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Mon 6/2

7:30 pm-12:57 pm

2 stops14h 27m

$1,414

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Best time to book a flight from Irvine to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Irvine with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Santiago de los Caballeros

How far ahead should I book a flight from Irvine to Santiago de los Caballeros?

The price you pay for your flight from Irvine to Santiago de los Caballeros may vary depending on when you book. For the best chance of a lower fare, look to book 22 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Irvine to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Irvine to Santiago de los Caballeros (average of $347). Flying from Irvine to Santiago de los Caballeros in July is currently the most expensive (average of $631). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to STI?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Irvine to Santiago de los Caballeros as you normally would.

Rainfall in Santiago de los Caballeros by month

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

Temperature in Santiago de los Caballeros by month

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Santiago de los Caballeros

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,920 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

8,685 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

JetBlue

7.3

Good

2,924 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Spirit Airlines

6.3

Okay

7,940 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What airport do you fly into for flights to Santiago de los Caballeros from Irvine?
Most people fly into Santiago de los Caballeros (STI) if they book a flight to Santiago de los Caballeros from Irvine. On average, Santiago has 0 inbound flights from Irvine per day from 4 airlines. Santiago de los Caballeros is conveniently located just 6.8 mi from Santiago de los Caballeros’s city center.
What are the cheapest airlines to fly from Irvine to Santiago de los Caballeros one-way?
To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $202. Delta flights start at $235 while deals on Frontier start at $255 one-way.
Can I find deals for flights from Irvine to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on Irvine to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Irvine to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Santiago de los Caballeros.
Can I find deals for business class flights from Irvine to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from Irvine to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Irvine to Santiago de los Caballeros?
Currently, May is the cheapest month in which you can book a flight from Irvine to Santiago de los Caballeros (average of $347). Flying from Irvine to Santiago de los Caballeros in July is currently the most expensive (average of $631). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Irvine to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
Copa Airlines	Cheapest$381	Average$460	FlexibilityNo cancel fee	On-time70%
United Airlines	Cheapest$423	Average$722	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$425	Average$697	FlexibilityNo cancel fee	On-time71%
JetBlue	Cheapest$446	Average$554	FlexibilityNo cancel fee	On-time62%

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$202+ Cheap flights from Irvine, CA to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Irvine to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Irvine to Santiago de los Caballeros are usually found in September or October, booked 23 days in advance, depart on a Wednesday or Tuesday and return on a Monday

Cheap flight deals from Irvine to Santiago de los Caballeros

Keep the following information in mind while searching for Irvine to Santiago de los Caballeros flight deals. Data was last updated April 24, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Irvine to Santiago de los Caballeros

Cheapest flights from Irvine to Santiago de los CaballerosExplore the most affordable flight options available from Irvine to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

Explore the most affordable flight options available from Irvine to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Irvine to Santiago de los Caballeros that are best for you.

Best time to book a flight from Irvine to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Irvine with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Santiago de los Caballeros

How far ahead should I book a flight from Irvine to Santiago de los Caballeros?

Use this chart to determine the optimal time to book a round-trip flight from Irvine to Santiago de los Caballeros. Price data was last updated on April 18, 2025.

What is the cheapest month to book a flight from Irvine to Santiago de los Caballeros?

What is the cheapest time of day to fly from IR9 to STI?

Find hourly flight availability from Irvine to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2025.

Rainfall in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average rainfall totals by month.

Temperature in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average temperature totals by month.

Reviews of airlines servicing Santiago de los Caballeros

Related info for your journey

Find useful and relevant information for your journey from Irvine to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santiago de los Caballeros from Irvine?

What are the cheapest airlines to fly from Irvine to Santiago de los Caballeros one-way?

Can I find deals for flights from Irvine to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from Irvine to Santiago de los Caballeros?

Can I find deals for business class flights from Irvine to Santiago de los Caballeros?

What is the cheapest month to book a flight from Irvine to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Irvine to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Irvine to Santiago de los Caballeros

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Cheapest flights from Irvine to Santiago de los Caballeros
Explore the most affordable flight options available from Irvine to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.