What are the cheapest airlines to fly from Durham to Santiago de los Caballeros one-way?

To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $196. American Airlines flights start at $210 while deals on United Airlines start at $236 one-way.

What is the cheapest day to fly from Durham to Santiago de los Caballeros?

Travelers seeking maximum savings on their Durham to Santiago de los Caballeros flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

What are the most popular airlines that fly from Durham to Santiago de los Caballeros?

American Airlines, JetBlue and Delta are the most popular airlines when flying from Durham to Santiago de los Caballeros.

How far in advance should I book a flight from Durham to Santiago de los Caballeros?

Find a great deal and save up to 21% by booking at least 22 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Durham to Santiago de los Caballeros within the next two weeks, with the cheapest ticket starting at $409.

What is the cheapest month to fly from Durham to Santiago de los Caballeros?

The best pricing can be found in the month of May. Prices to Santiago de los Caballeros from Durham average $582. You can even find prices in May for less than $582, as users have found deals to Santiago de los Caballeros from as low as $353. The month of July appears to be one of the more expensive times to travel to Santiago de los Caballeros from Durham. Flying in the targeted month can save you up to 29%.

What airport do you fly into for flights to Santiago de los Caballeros from Durham?

Santiago de los Caballeros (STI) is the airport you will fly into if you book a flight from Durham to Santiago de los Caballeros. You should not have trouble finding flights to Santiago from Durham; the airport handles an average of 0 inbound flights from Durham per day. You should also have plenty of airline options to choose from since 4 airlines have flights to the Santiago de los Caballeros airport from Durham. It is only a 6.8 mi journey from Santiago (STI) to Santiago de los Caballeros’s city center.

How can I find direct flights from Durham to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Santiago de los Caballeros.

Can I find deals for business class flights from Durham to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from Durham to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$196+ Flights from Durham to Santiago de los Caballeros

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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Durham to Santiago de los Caballeros are usually found in May or September, booked 21 days in advance, depart on a Tuesday or Monday and return on a Friday

Cheap flight deals from Durham to Santiago de los Caballeros

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$387 (Delta)
One-way from	$196 (Cheapflightsfares)
Popular in	July
Cheapest in	May
Average price	$586

Provider with most accurate pricing for Raleigh-Durham-Santiago de los Caballeros flight deals.

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Provider most trusted by Cheapflights users for Raleigh-Durham-Santiago de los Caballeros flights.

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From Durham to Santiago de los Caballeros

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One-way flight from Durham to Santiago de los Caballeros

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Highest demand for flights based on searches. 8% potential increase in price ($56 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).

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Average for round-trip flights in April 2025

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Find flight deals from Durham to Santiago de los Caballeros

Cheapest flights from Durham to Santiago de los Caballeros
Explore the most affordable flight options available from Durham to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

Sun 6/17:00 amRDU - STI

1 stop10h 50mDelta

Fri 6/66:11 amSTI - RDU

1 stop10h 37mDelta

Deal found 4/22

$387

Sun 6/110:45 pmRDU - STI

2 stops15h 17mFrontier

Fri 6/63:22 pmSTI - RDU

2 stops20h 15mFrontier

Deal found 4/22

$404

Sat 6/76:00 amRDU - STI

1 stop15h 05mAmerican Airlines

Tue 6/247:05 amSTI - RDU

2 stops16h 54mAmerican Airlines

Deal found 4/23

$455

Wed 5/219:52 amRDU - STI

1 stop10h 38mJetBlue

Thu 6/55:20 amSTI - RDU

1 stop10h 23mJetBlue

Deal found 4/22

$468

Wed 5/218:00 amRDU - STI

2 stops30h 48mMultiple Airlines

Thu 6/53:53 pmSTI - RDU

1 stop17h 19mMultiple Airlines

Deal found 4/22

$567

Best flights from Durham to Santiago de los Caballeros
Discover carefully curated flight deals from Durham to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2025.

Sun 6/17:00 amRDU - STI

1 stop10h 50mDelta

Fri 6/66:11 amSTI - RDU

1 stop10h 37mDelta

Deal found 4/22

$387

Sun 6/110:45 pmRDU - STI

2 stops15h 17mFrontier

Fri 6/63:22 pmSTI - RDU

2 stops20h 15mFrontier

Deal found 4/22

$404

Sat 6/76:00 amRDU - STI

1 stop15h 05mAmerican Airlines

Tue 6/247:05 amSTI - RDU

2 stops16h 54mAmerican Airlines

Deal found 4/23

$455

Wed 5/219:52 amRDU - STI

1 stop10h 38mJetBlue

Thu 6/55:20 amSTI - RDU

1 stop10h 23mJetBlue

Deal found 4/22

$468

Wed 5/218:00 amRDU - STI

2 stops30h 48mMultiple Airlines

Thu 6/53:53 pmSTI - RDU

1 stop17h 19mMultiple Airlines

Deal found 4/22

$567

Last-minute flights from Durham to Santiago de los Caballeros
Discover last-minute flight deals from Durham to Santiago de los Caballeros. Data last updated April 24, 2025 and is based on user searches.

Wed 4/308:20 pmRDU - STI

2 stops18h 06mAmerican Airlines

Sun 5/43:16 pmSTI - RDU

1 stop18h 02mAmerican Airlines

Deal found 4/23

$547

Wed 4/309:50 amRDU - STI

1 stop11h 40mJetBlue

Sat 5/33:51 amSTI - RDU

1 stop12h 33mJetBlue

Deal found 4/23

$836

Wed 4/3010:38 amRDU - STI

3 stops28h 08mMultiple Airlines

Sun 5/43:51 pmSTI - RDU

2 stops17h 12mMultiple Airlines

Deal found 4/23

$1,095

Thu 5/86:18 pmRDU - STI

2 stops20h 42mAmerican Airlines

Wed 5/283:50 pmSTI - RDU

2 stops16h 22mAmerican Airlines

Deal found 4/23

$497

Wed 5/219:52 amRDU - STI

1 stop10h 38mJetBlue

Thu 6/55:20 amSTI - RDU

1 stop10h 23mJetBlue

Deal found 4/22

$468

Wed 5/218:00 amRDU - STI

2 stops30h 48mMultiple Airlines

Thu 6/53:53 pmSTI - RDU

1 stop17h 19mMultiple Airlines

Deal found 4/22

$567

Wed 5/287:00 amRDU - STI

1 stop10h 50mDelta

Wed 6/46:11 amSTI - RDU

1 stop10h 37mDelta

Deal found 4/23

$433

One-way flights from Durham to Santiago de los Caballeros
Search for one-way flight options from Durham to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated April 24, 2025.

Wed 8/68:43 pmRDU - STI

1 stop13h 20mSpirit Airlines

Deal found 4/23

$196

Wed 8/611:22 amRDU - STI

2 stops10h 23mAmerican Airlines

Deal found 4/23

$210

Wed 5/216:00 amRDU - STI

1 stop6h 57mUnited Airlines

Deal found 4/23

$236

Wed 5/218:00 amRDU - STI

2 stops30h 48mMultiple Airlines

Deal found 4/23

$346

Sat 5/249:10 pmRDU - STI

1 stop11h 55mJetBlue

Deal found 4/23

$353

Cheapflights Fare Finder

Use the filters below to find and compare flights from Durham to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Sun 6/1

7:00 am-5:50 pm

1 stop10h 50m

Santiago de los Caballeros

Fri 6/6

6:11 am-4:48 pm

1 stop10h 37m

$387

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Sun 6/1

10:45 pm-2:02 pm

2 stops15h 17m

Santiago de los Caballeros

Fri 6/6

3:22 pm-11:37 am

2 stops20h 15m

$404

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Sat 6/7

6:00 am-9:05 pm

1 stop15h 05m

Santiago de los Caballeros

Tue 6/24

7:05 am-11:59 pm

2 stops16h 54m

$455

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Wed 5/21

9:52 am-8:30 pm

1 stop10h 38m

Santiago de los Caballeros

Thu 6/5

5:20 am-3:43 pm

1 stop10h 23m

$468

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Wed 5/21

8:00 am-2:48 pm

2 stops30h 48m

Santiago de los Caballeros

Thu 6/5

3:53 pm-9:12 am

1 stop17h 19m

$567

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Wed 8/6

8:43 pm-10:03 am

1 stop13h 20m

$196

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Wed 8/6

11:22 am-9:45 pm

2 stops10h 23m

$210

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Wed 5/21

6:00 am-12:57 pm

1 stop6h 57m

$236

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Wed 5/21

8:00 am-2:48 pm

2 stops30h 48m

$346

RaleighSantiago de los Caballeros

RDU - STI

RDUSTI

Raleigh-Durham

Sat 5/24

9:10 pm-9:05 am

1 stop11h 55m

$353

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Best time to book a flight from Durham to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Durham with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Santiago de los Caballeros

How far ahead should I book a flight from Durham to Santiago de los Caballeros?

The best time to book flights from Durham to Santiago de los Caballeros is 21 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Durham to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Durham to Santiago de los Caballeros (average of $347). Flying from Durham to Santiago de los Caballeros in July is currently the most expensive (average of $631). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to STI?

When flying from Durham to Santiago de los Caballeros, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Santiago de los Caballeros by month

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

Temperature in Santiago de los Caballeros by month

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Santiago de los Caballeros

See what other customers who have flown with Delta, United Airlines and JetBlue from Durham to Santiago de los Caballeros have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,920 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

8,685 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

JetBlue

7.3

Good

2,924 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Spirit Airlines

6.3

Okay

7,942 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What airport do you fly into for flights to Santiago de los Caballeros from Durham?
Santiago de los Caballeros (STI) is the airport you will fly into if you book a flight from Durham to Santiago de los Caballeros. You should not have trouble finding flights to Santiago from Durham; the airport handles an average of 0 inbound flights from Durham per day. You should also have plenty of airline options to choose from since 4 airlines have flights to the Santiago de los Caballeros airport from Durham. It is only a 6.8 mi journey from Santiago (STI) to Santiago de los Caballeros’s city center.
What are the cheapest airlines to fly from Durham to Santiago de los Caballeros one-way?
To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $196. American Airlines flights start at $210 while deals on United Airlines start at $236 one-way.
Can I find deals for flights from Durham to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on Durham to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Durham to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Santiago de los Caballeros.
Can I find deals for business class flights from Durham to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from Durham to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Durham to Santiago de los Caballeros?
Currently, May is the cheapest month in which you can book a flight from Durham to Santiago de los Caballeros (average of $347). Flying from Durham to Santiago de los Caballeros in July is currently the most expensive (average of $631). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Durham to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$353	Average$634	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$353	Average$442	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$366	Average$611	FlexibilityNo cancel fee	On-time71%
JetBlue	Cheapest$391	Average$521	FlexibilityNo cancel fee	On-time62%

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$196+ Cheap flights from Durham, NC to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Durham to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Durham to Santiago de los Caballeros are usually found in May or September, booked 21 days in advance, depart on a Tuesday or Monday and return on a Friday

Cheap flight deals from Durham to Santiago de los Caballeros

Keep the following information in mind while searching for Durham to Santiago de los Caballeros flight deals. Data was last updated April 24, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Durham to Santiago de los Caballeros

Cheapest flights from Durham to Santiago de los CaballerosExplore the most affordable flight options available from Durham to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

Explore the most affordable flight options available from Durham to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Durham to Santiago de los Caballeros that are best for you.

Best time to book a flight from Durham to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Durham with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Durham to Santiago de los Caballeros

How far ahead should I book a flight from Durham to Santiago de los Caballeros?

Use this chart to determine the optimal time to book a round-trip flight from Durham to Santiago de los Caballeros. Price data was last updated on April 18, 2025.

What is the cheapest month to book a flight from Durham to Santiago de los Caballeros?

What is the cheapest time of day to fly from DU8 to STI?

Find hourly flight availability from Durham to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2025.

Rainfall in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average rainfall totals by month.

Temperature in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average temperature totals by month.

Reviews of airlines servicing Santiago de los Caballeros

See what other customers who have flown with Delta, United Airlines and JetBlue from Durham to Santiago de los Caballeros have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Durham to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santiago de los Caballeros from Durham?

What are the cheapest airlines to fly from Durham to Santiago de los Caballeros one-way?

Can I find deals for flights from Durham to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from Durham to Santiago de los Caballeros?

Can I find deals for business class flights from Durham to Santiago de los Caballeros?

What is the cheapest month to book a flight from Durham to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Durham to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Durham to Santiago de los Caballeros

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Cheapest flights from Durham to Santiago de los Caballeros
Explore the most affordable flight options available from Durham to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.