What are the cheapest airlines flying from St. Louis to Santiago round-trip?

Flying on Delta is currently your cheapest option to Santiago, with prices starting at $804. Additional round-trip tickets that might be worth considering are offered by LATAM Airlines and United Airlines, with the lowest prices starting at $1,208 and $1,294, respectively. These flights start at 17% lower than the current average price 3 months from now.

What is the cheapest day to fly from St. Louis to Santiago?

Travelers seeking maximum savings on their St. Louis to Santiago flight should consider departing on Wednesday mornings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

What are the most popular airlines that fly from St. Louis to Santiago?

When booking a flight from St. Louis to Santiago, you may want to consider flying on American Airlines, Delta or LATAM Airlines as they are the most popular for this route.

What is the cheapest day to fly round-trip from St. Louis to Santiago?

Travelers have found that booking a Tuesday departure is the best way to save up to 24% on the cost of booking your flights compared to booking on days of the week where this route is of high demand.

How far in advance should I book a flight from St. Louis to Santiago?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 50 days in advance, which can save you up to 1% on flights from St. Louis to Santiago compared to booking the week you need them. Waiting 50 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $687. For sooner than that we have options available in the next 3 days from $687.

What is the cheapest month to fly from St. Louis to Santiago?

Our data shows that October tends to be the cheapest month to fly to Santiago from St. Louis. Users have commonly found prices around $974 for the month, but tickets can be as low as $728. Due to multiple factors, prepare for potentially higher prices in December.

Most accurate provider : When it comes to deals on St. Louis-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Santiago flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on St. Louis-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from St. Louis to Santiago that include hotel bookings?

Yes. In addition to deals on St. Louis to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from St. Louis to Santiago?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Santiago.

Can I find deals for business class flights from St. Louis to Santiago?

Yes. Cheapflights offers flight deals from St. Louis to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$804+ Flights from St. Louis to Santiago

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1. Tell us where you want to go

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The best prices from Lambert-St Louis to Santiago Arturo Merino Benitez are usually found in October or July, booked 49 days in advance, depart on a Wednesday or Monday and return on a Tuesday

Cheap flight deals from St. Louis to Santiago

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$804
Popular in	December
Cheapest in	October
Average price	$1,183

Provider with most accurate pricing for Lambert-St Louis-Santiago Arturo Merino Benitez flight deals.

Search Deals

Provider most trusted by Cheapflights users for Lambert-St Louis-Santiago Arturo Merino Benitez flights.

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From Lambert-St Louis to Santiago Arturo Merino Benitez

Search Deals

Highest demand for flights based on searches. 5% potential increase in price ($62 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($21 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in February 2025

Search Deals

Find flight deals from St. Louis to Santiago

Cheapest flights from St. Louis to Santiago
Explore the most affordable flight options available from St. Louis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

Wed 7/303:30 pmSTL - SCL

1 stop14h 30mDelta

Thu 8/78:40 pmSCL - STL

1 stop16h 44mDelta

Deal found 2/19

$804

Sat 11/11:54 pmSTL - SCL

1 stop15h 56mAmerican Airlines

Sat 11/2211:45 pmSCL - STL

2 stops19h 21mAmerican Airlines

Deal found 2/20

$888

Sat 11/13:30 pmSTL - SCL

1 stop13h 30mLATAM Airlines

Fri 11/2112:30 amSCL - STL

2 stops20h 33mLATAM Airlines

Deal found 2/20

$919

Fri 3/75:24 pmSTL - SCL

1 stop34h 36mMultiple Airlines

Fri 3/146:00 amSCL - STL

2 stops34h 43mMultiple Airlines

Deal found 2/19

$1,045

Wed 3/1210:55 amSTL - SCL

1 stop18h 55mUnited Airlines

Sun 3/239:45 pmSCL - STL

1 stop19h 31mUnited Airlines

Deal found 2/20

$1,294

Fri 5/28:00 amSTL - SCL

2 stops20h 04mCopa Airlines

Thu 5/1512:13 amSCL - STL

2 stops20h 22mCopa Airlines

Deal found 2/20

$5,375

Best flights from St. Louis to Santiago
Discover carefully curated flight deals from St. Louis to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 20, 2025.

Wed 7/303:30 pmSTL - SCL

1 stop14h 30mDelta

Thu 8/78:40 pmSCL - STL

1 stop16h 44mDelta

Deal found 2/19

$804

Fri 3/75:24 pmSTL - SCL

1 stop34h 36mMultiple Airlines

Fri 3/146:00 amSCL - STL

2 stops34h 43mMultiple Airlines

Deal found 2/19

$1,045

Wed 3/1210:19 amSTL - SCL

1 stop18h 01mLATAM Airlines

Sat 3/2210:00 amSCL - STL

2 stops15h 31mLATAM Airlines

Deal found 2/20

$1,208

Wed 3/1210:55 amSTL - SCL

1 stop18h 55mUnited Airlines

Sun 3/239:45 pmSCL - STL

1 stop19h 31mUnited Airlines

Deal found 2/20

$1,294

Fri 5/26:09 pmSTL - SCL

1 stop11h 46mAmerican Airlines

Fri 5/169:55 pmSCL - STL

1 stop20h 34mAmerican Airlines

Deal found 2/20

$5,354

Fri 5/28:00 amSTL - SCL

2 stops20h 04mCopa Airlines

Thu 5/1512:13 amSCL - STL

2 stops20h 22mCopa Airlines

Deal found 2/20

$5,375

Last-minute flights from St. Louis to Santiago
Discover last-minute flight deals from St. Louis to Santiago. Data last updated February 20, 2025 and is based on user searches.

Fri 3/75:24 pmSTL - SCL

1 stop34h 36mMultiple Airlines

Fri 3/146:00 amSCL - STL

2 stops34h 43mMultiple Airlines

Deal found 2/19

$1,045

Wed 3/121:06 pmSTL - SCL

1 stop15h 14mLATAM Airlines

Sun 3/234:00 pmSCL - STL

2 stops28h 05mLATAM Airlines

Deal found 2/20

$1,164

Wed 3/127:10 amSTL - SCL

2 stops21h 15mDelta

Sat 3/2212:25 amSCL - STL

2 stops21h 53mDelta

Deal found 2/20

$1,204

Wed 3/1210:55 amSTL - SCL

1 stop18h 55mUnited Airlines

Sun 3/239:45 pmSCL - STL

1 stop19h 31mUnited Airlines

Deal found 2/20

$1,294

Find flights from St. Louis to Santiago within your budget

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 7/30

3:30 pm-7:00 am

1 stop14h 30m

Santiago Arturo Merino Benitez

Thu 8/7

8:40 pm-12:24 pm

1 stop16h 44m

$804

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Fri 3/7

5:24 pm-7:00 am

1 stop34h 36m

Santiago Arturo Merino Benitez

Fri 3/14

6:00 am-2:43 pm

2 stops34h 43m

$1,045

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/12

10:19 am-6:20 am

1 stop18h 01m

Santiago Arturo Merino Benitez

Sat 3/22

10:00 am-11:31 pm

2 stops15h 31m

$1,208

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/12

10:55 am-7:50 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Sun 3/23

9:45 pm-3:16 pm

1 stop19h 31m

$1,294

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Fri 5/2

6:09 pm-6:55 am

1 stop11h 46m

Santiago Arturo Merino Benitez

Fri 5/16

9:55 pm-5:29 pm

1 stop20h 34m

$5,354

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Fri 5/2

8:00 am-5:04 am

2 stops20h 04m

Santiago Arturo Merino Benitez

Thu 5/15

12:13 am-7:35 pm

2 stops20h 22m

$5,375

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Compare providers for flights from St. Louis to Santiago

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santiago in February.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
AranGrant	Price Accuracy3 stars	Trust Score*1 star
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
Cheapfaremart	Price Accuracy-	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on St. Louis-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Santiago flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on St. Louis-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from St. Louis to Santiago

Get recent, data-driven insights about flights from St. Louis to Santiago including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from St. Louis to Santiago?

To ensure you get the cheapest price possible for a flight from St. Louis to Santiago, you should look to book at least 49 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from St. Louis to Santiago?

Currently, April is the cheapest month in which you can book a flight from St. Louis to Santiago (average of $752). Flying from St. Louis to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to SCL?

A simple way to save on the total cost of your ticket is to fly from St. Louis to Santiago at noon. If you’re flexible enough to do this you can expect to save up to 9% on your trip compared to booking a flight in the morning.

Rainfall in Santiago by month

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Delta

8.0

Very good

8,219 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

8,219 reviews

Delta

8.0

Very good

8,219 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines

7.6

Good

1,510 reviews

Delta

8.0

Very good

8,219 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines

7.5

Good

1,795 reviews

Delta

8.0

Very good

8,219 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

8,765 reviews

Delta

8.0

Very good

8,219 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

8,219 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What are the cheapest airlines flying from St. Louis to Santiago round-trip?
Flying on Delta is currently your cheapest option to Santiago, with prices starting at $804. Additional round-trip tickets that might be worth considering are offered by LATAM Airlines and United Airlines, with the lowest prices starting at $1,208 and $1,294, respectively. These flights start at 17% lower than the current average price 3 months from now.
Can I find deals for flights from St. Louis to Santiago that include hotel bookings?
Yes. In addition to deals on St. Louis to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to Santiago?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Santiago.
Can I find deals for business class flights from St. Louis to Santiago?
Yes. Cheapflights offers flight deals from St. Louis to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from St. Louis to Santiago?
Currently, April is the cheapest month in which you can book a flight from St. Louis to Santiago (average of $752). Flying from St. Louis to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Santiago

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St. Louis to Easter Island flights

Other flights to Santiago

Top 4 airlines flying from St. Louis to Santiago

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$706	Average$1,049	FlexibilityNo cancel fee	On-timeN/A
LATAM Airlines	Cheapest$762	Average$1,019	FlexibilityNo cancel fee	On-time81%
American Airlines	Cheapest$808	Average$947	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$883	Average$1,002	FlexibilityNo cancel fee	On-time69%

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$804+ Cheap flights from St. Louis (STL) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/30. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from St. Louis to Santiago with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

The best prices from Lambert-St Louis to Santiago Arturo Merino Benitez are usually found in October or July, booked 49 days in advance, depart on a Wednesday or Monday and return on a Tuesday

Cheap flight deals from St. Louis to Santiago

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Find flight deals from St. Louis to Santiago

Cheapest flights from St. Louis to SantiagoExplore the most affordable flight options available from St. Louis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

Explore the most affordable flight options available from St. Louis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

Find flights from St. Louis to Santiago within your budget

Compare providers for flights from St. Louis to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santiago in February.

Best time to book a flight from St. Louis to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from St. Louis with our price prediction graph.

Travel insights for flights from St. Louis to Santiago

Get recent, data-driven insights about flights from St. Louis to Santiago including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from St. Louis to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Santiago. Price data was last updated on February 14, 2025.

What is the cheapest month to book a flight from St. Louis to Santiago?

What is the cheapest time of day to fly from STL to SCL?

Find hourly flight availability from St. Louis to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

Reviews of airlines servicing Santiago

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from St. Louis to Santiago round-trip?

Can I find deals for flights from St. Louis to Santiago that include hotel bookings?

How can I find direct flights from St. Louis to Santiago?

Can I find deals for business class flights from St. Louis to Santiago?

What is the cheapest month to book a flight from St. Louis to Santiago?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Santiago

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Top 4 airlines flying from St. Louis to Santiago

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Cheapest flights from St. Louis to Santiago
Explore the most affordable flight options available from St. Louis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.