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$387+ Cheap flights from South Carolina to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/17. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SCL
Jan 26 — Feb 21
Sun 1/26
Sun 2/2
1 adult, Economy
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Cheap flight deals from South Carolina to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from South Carolina (USSC) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$691
(Avianca Connect)

One-way from

$387
(Kiwi.com)
From South Carolina to Santiago Arturo Merino Benitez
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One-way flight from South Carolina to Santiago Arturo Merino Benitez
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Find flight deals from South Carolina to Santiago

Cheapest flights from South Carolina to Santiago
Explore the most affordable flight options available from South Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This Avianca Connect deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/176:52 amCLT - SCL
2 stops21h 18mMultiple Airlines
Tue 4/13:30 pmSCL - CLT
2 stops21h 40mMultiple Airlines
Deal found 1/21$691
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/261:15 pmCLT - SCL
1 stop17h 45mDelta
Tue 7/88:40 pmSCL - CLT
1 stop15h 50mDelta
Deal found 1/21$754
This LATAM Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/254:30 pmCLT - SCL
2 stops14h 00mLATAM Airlines
Sun 7/611:25 pmSCL - CLT
2 stops23h 00mLATAM Airlines
Deal found 1/21$758
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/154:37 pmCHS - SCL
1 stop14h 58mAmerican Airlines
Wed 3/2610:44 pmSCL - CHS
1 stop20h 36mAmerican Airlines
Deal found 1/21$764
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/156:00 amCHS - SCL
2 stops24h 50mUnited Airlines
Wed 3/269:45 pmSCL - CHS
2 stops27h 29mUnited Airlines
Deal found 1/21$768
This LATAM Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/158:15 amCHS - SCL
2 stops19h 20mLATAM Airlines
Tue 3/2512:25 amSCL - CHS
2 stops34h 01mLATAM Airlines
Deal found 1/21$788
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/256:40 pmGSP - SCL
1 stop12h 20mDelta
Sun 7/611:25 pmSCL - GSP
2 stops24h 20mDelta
Deal found 1/21$794
This Air Canada deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/49:20 amCLT - SCL
1 stop24h 50mAir Canada
Tue 2/258:50 pmSCL - CLT
1 stop25h 59mAir Canada
Deal found 1/21$857
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/33:56 pmMYR - SCL
3 stops35h 54mMultiple Airlines
Mon 2/108:10 amSCL - MYR
3 stops32h 05mMultiple Airlines
Deal found 1/20$857
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/154:30 pmCHS - SCL
1 stop12h 50mDelta
Tue 3/2512:25 amSCL - CHS
2 stops19h 34mDelta
Deal found 1/21$904
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/317:15 amCHS - SCL
3 stops20h 24mMultiple Airlines
Fri 2/145:20 amSCL - CHS
2 stops17h 59mMultiple Airlines
Deal found 1/20$935
This United deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/47:00 amCLT - SCL
2 stops23h 50mUnited Airlines
Tue 2/2510:45 pmSCL - CLT
2 stops24h 17mUnited Airlines
Deal found 1/21$1,062

Find flights from South Carolina to Santiago within your budget

Customize your flight search to find flights from South Carolina to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 3/17

6:52 am-5:10 am

2 stops21h 18m

Santiago Arturo Merino Benitez

Tue 4/1

3:30 pm-12:10 pm

2 stops21h 40m

$691

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Thu 6/26

1:15 pm-7:00 am

1 stop17h 45m

Santiago Arturo Merino Benitez

Tue 7/8

8:40 pm-12:30 pm

1 stop15h 50m

$754

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 6/25

4:30 pm-6:30 am

2 stops14h 00m

Santiago Arturo Merino Benitez

Sun 7/6

11:25 pm-10:25 pm

2 stops23h 00m

$758

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Sat 3/15

4:37 pm-8:35 am

1 stop14h 58m

Santiago Arturo Merino Benitez

Wed 3/26

10:44 pm-6:20 pm

1 stop20h 36m

$764

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Sat 3/15

6:00 am-7:50 am

2 stops24h 50m

Santiago Arturo Merino Benitez

Wed 3/26

9:45 pm-12:14 am

2 stops27h 29m

$768

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Sat 3/15

8:15 am-4:35 am

2 stops19h 20m

Santiago Arturo Merino Benitez

Tue 3/25

12:25 am-9:26 am

2 stops34h 01m

$788

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Wed 6/25

6:40 pm-7:00 am

1 stop12h 20m

Santiago Arturo Merino Benitez

Sun 7/6

11:25 pm-11:45 pm

2 stops24h 20m

$794

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Tue 2/4

9:20 am-12:10 pm

1 stop24h 50m

Santiago Arturo Merino Benitez

Tue 2/25

8:50 pm-8:49 pm

1 stop25h 59m

$857

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

Mon 2/3

3:56 pm-5:50 am

3 stops35h 54m

Santiago Arturo Merino Benitez

Mon 2/10

8:10 am-2:15 pm

3 stops32h 05m

$857

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Sat 3/15

4:30 pm-6:20 am

1 stop12h 50m

Santiago Arturo Merino Benitez

Tue 3/25

12:25 am-6:59 pm

2 stops19h 34m

$904

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 28 results
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Best time to book a flight from South Carolina to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to Santiago

Get recent, data-driven insights about flights from South Carolina to Santiago including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to Santiago?

Currently, April is the cheapest month in which you can book a flight from South Carolina to Santiago (average of $752). Flying from South Carolina to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SCL?

Find hourly flight availability from South Carolina to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

When flying from South Carolina to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated January 21, 2025.
To help decide which airline to fly from South Carolina to Santiago, see what other customers have to say about Copa Airlines, LATAM Airlines and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,521 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,521 reviews
Delta
8.0
Very good
8,521 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines
7.7
Good
1,662 reviews
Delta
8.0
Very good
8,521 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines
7.5
Good
1,858 reviews
Delta
8.0
Very good
8,521 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
8,985 reviews
Delta
8.0
Very good
8,521 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,521 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from South Carolina?

    For a flight from South Carolina to Santiago, you will be flying into Arturo Merino Benitez. Santiago Arturo Merino Benitez (SCL) is just 8.4 mi from the center of the city.

  • What are the most popular routes from South Carolina to Santiago?

    The most popular flight routes from South Carolina to Santiago are Charlotte Douglas - Santiago Arturo Merino Benitez, Charleston - Santiago Arturo Merino Benitez and Myrtle Beach Intl - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from South Carolina to Santiago that include hotel bookings?

    Yes. In addition to deals on South Carolina to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santiago.

  • Can I find deals for business class flights from South Carolina to Santiago?

    Yes. Cheapflights offers flight deals from South Carolina to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Santiago?

    Currently, April is the cheapest month in which you can book a flight from South Carolina to Santiago (average of $752). Flying from South Carolina to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from South Carolina to Santiago

Discover the top 3 airlines that operate flights from South Carolina to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$577Average$853FlexibilityNo cancel feeOn-time81%
DeltaCheapest$617Average$974FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$702Average$880FlexibilityNo cancel feeOn-time71%
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