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$654+ Cheap flights from South Carolina to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SCL
feb. 25 — mar. 41
mar. 2/25
mar. 3/4
1 adult, Economy
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Cheap flight deals from South Carolina to Santiago

Keep the following information in mind while searching for South Carolina to Santiago flight deals. Data was last updated febrero 20, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
1 star

Round-trip from

$654
(Avianca Connect)
Provider with most accurate pricing for Myrtle Beach Intl-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Santiago Arturo Merino Benitez flights.
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From South Carolina to Santiago Arturo Merino Benitez
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Find flight deals from South Carolina to Santiago

Cheapest flights from South Carolina to Santiago
Explore the most affordable flight options available from South Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 20, 2025.

This Avianca Connect deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/2510:30 amCLT - SCL
2 stops17h 45mMultiple Airlines
mar. 4/292:30 pmSCL - CLT
2 stops21h 44mMultiple Airlines
Deal found 2/20$654
This LATAM Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/227:30 pmCLT - SCL
2 stops21h 05mLATAM Airlines
mar. 12/25:15 amSCL - CLT
2 stops20h 43mLATAM Airlines
Deal found 2/20$794
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/237:37 pmCLT - SCL
2 stops17h 48mDelta
lun. 4/284:55 pmSCL - CLT
2 stops21h 59mDelta
Deal found 2/20$804
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/225:13 pmSAV - SCL
1 stop12h 47mDelta
mié. 10/2911:15 pmSCL - SAV
1 stop19h 15mDelta
Deal found 2/19$874
This LATAM Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/227:50 pmSAV - SCL
2 stops33h 40mLATAM Airlines
mar. 10/76:30 amSCL - SAV
2 stops18h 36mLATAM Airlines
Deal found 2/19$878
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/219:08 pmGSP - SCL
1 stop31h 52mMultiple Airlines
jue. 3/273:32 amSCL - GSP
2 stops18h 48mMultiple Airlines
Deal found 2/20$907
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/306:18 pmGSP - SCL
1 stop12h 47mAmerican Airlines
vie. 6/209:55 pmSCL - GSP
1 stop21h 32mAmerican Airlines
Deal found 2/20$934
This LATAM Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/3012:00 pmGSP - SCL
2 stops18h 30mLATAM Airlines
vie. 6/2010:55 pmSCL - GSP
2 stops19h 24mLATAM Airlines
Deal found 2/20$978
This StudentUniverse deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure StudentUniverse is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/256:00 amCLT - SCL
2 stops16h 44mCopa Airlines
lun. 4/282:30 amSCL - CLT
2 stops16h 24mCopa Airlines
Deal found 2/20$986
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 4/124:27 pmSAV - SCL
2 stops14h 28mAmerican Airlines
sáb. 4/269:55 pmSCL - SAV
1 stop26h 04mAmerican Airlines
Deal found 2/20$1,037
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/174:53 pmCHS - SCL
1 stop13h 57mUnited Airlines
mié. 3/269:45 pmSCL - CHS
1 stop18h 53mUnited Airlines
Deal found 2/20$1,054
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/2111:45 amCHS - SCL
1 stop17h 15mDelta
mar. 11/2510:55 pmSCL - CHS
1 stop19h 53mDelta
Deal found 2/19$1,084

Find flights from South Carolina to Santiago within your budget

Customize your flight search to find flights from South Carolina to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.

Fly from

South Carolina

Fly to

Santiago

Route

Depart

Return

Price

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

vie. 4/25

10:30 am-4:15 am

2 stops17h 45m

Santiago Arturo Merino Benitez

mar. 4/29

2:30 pm-12:14 pm

2 stops21h 44m

$654

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

mié. 4/23

7:37 pm-1:25 pm

2 stops17h 48m

Santiago Arturo Merino Benitez

lun. 4/28

4:55 pm-2:54 pm

2 stops21h 59m

$804

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

jue. 5/1

3:40 pm-6:50 am

2 stops15h 10m

Santiago Arturo Merino Benitez

dom. 5/4

12:30 am-11:46 pm

3 stops23h 16m

$808

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

vie. 3/21

9:08 pm-6:00 am

1 stop31h 52m

Santiago Arturo Merino Benitez

jue. 3/27

3:32 am-9:20 pm

2 stops18h 48m

$907

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

vie. 5/30

6:18 pm-7:05 am

1 stop12h 47m

Santiago Arturo Merino Benitez

vie. 6/20

9:55 pm-7:27 pm

1 stop21h 32m

$934

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

vie. 5/30

12:00 pm-6:30 am

2 stops18h 30m

Santiago Arturo Merino Benitez

vie. 6/20

10:55 pm-6:19 pm

2 stops19h 24m

$978

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

vie. 4/25

6:00 am-10:44 pm

2 stops16h 44m

Santiago Arturo Merino Benitez

lun. 4/28

2:30 am-6:54 pm

2 stops16h 24m

$986

SavannahSantiago

SAV - SCL

SAVSCL

Savannah/Hilton Head

vie. 5/2

7:55 pm-7:00 am

1 stop11h 05m

Santiago Arturo Merino Benitez

vie. 5/9

8:40 pm-9:19 am

1 stop12h 39m

$1,024

SavannahSantiago

SAV - SCL

SAVSCL

Savannah/Hilton Head

sáb. 4/12

4:27 pm-6:55 am

2 stops14h 28m

Santiago Arturo Merino Benitez

sáb. 4/26

9:55 pm-11:59 pm

1 stop26h 04m

$1,037

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

lun. 3/17

6:51 am-7:50 am

1 stop23h 59m

Santiago Arturo Merino Benitez

jue. 3/27

9:45 pm-3:38 pm

1 stop18h 53m

$1,054

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 14 results
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Best time to book a flight from South Carolina to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to Santiago

Get recent, data-driven insights about flights from South Carolina to Santiago including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to Santiago?

Currently, April is the cheapest month in which you can book a flight from South Carolina to Santiago (average of $752). Flying from South Carolina to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SCL?

Find hourly flight availability from South Carolina to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated febrero 20, 2025.

When flying from South Carolina to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated febrero 20, 2025.
To help decide which airline to fly from South Carolina to Santiago, see what other customers have to say about Delta, Copa Airlines and LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,219 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,219 reviews
Delta
8.0
Very good
8,219 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines
7.6
Good
1,510 reviews
Delta
8.0
Very good
8,219 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines
7.5
Good
1,795 reviews
Delta
8.0
Very good
8,219 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
8,765 reviews
Delta
8.0
Very good
8,219 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,219 reviews

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from South Carolina?

    For a flight from South Carolina to Santiago, you will be flying into Arturo Merino Benitez. Santiago Arturo Merino Benitez (SCL) is just 8.4 mi from the center of the city.

  • What are the most popular routes from South Carolina to Santiago?

    The most popular flight routes from South Carolina to Santiago are Charlotte Douglas - Santiago Arturo Merino Benitez, Charleston - Santiago Arturo Merino Benitez and Greenville - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from South Carolina to Santiago that include hotel bookings?

    Yes. In addition to deals on South Carolina to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santiago.

  • Can I find deals for business class flights from South Carolina to Santiago?

    Yes. Cheapflights offers flight deals from South Carolina to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Santiago?

    Currently, April is the cheapest month in which you can book a flight from South Carolina to Santiago (average of $752). Flying from South Carolina to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from South Carolina to Santiago

Discover the top 3 airlines that operate flights from South Carolina to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$577Average$853FlexibilityNo cancel feeOn-time81%
DeltaCheapest$617Average$974FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$732Average$978FlexibilityNo cancel feeOn-time71%
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