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$278+ Cheap flights from South Carolina to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SCL
abr. 7 — abr. 141
lun. 4/7
lun. 4/14
1 adult, Economy
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Cheap flight deals from South Carolina to Santiago

Keep the following information in mind while searching for South Carolina to Santiago flight deals. Data was last updated abril 2, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
1 star

Round-trip from

$690
(Avianca Connect)

One-way from

$278
(Mytrip)
Provider with most accurate pricing for Myrtle Beach Intl-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Santiago Arturo Merino Benitez flights.
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From South Carolina to Santiago Arturo Merino Benitez
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One-way flight from South Carolina to Santiago Arturo Merino Benitez
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Find flight deals from South Carolina to Santiago

Cheapest flights from South Carolina to Santiago
Explore the most affordable flight options available from South Carolina to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 2, 2025.

This Avianca Connect deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/110:57 amCLT - SCL
2 stops17h 38mMultiple Airlines
jue. 5/82:30 pmSCL - CLT
2 stops20h 33mMultiple Airlines
Deal found 3/31$690
This Avianca Connect deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/126:00 amMYR - SCL
2 stops22h 15mMultiple Airlines
mar. 5/2711:55 pmSCL - MYR
2 stops21h 10mMultiple Airlines
Deal found 4/1$698
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/111:45 amCLT - SCL
1 stop19h 15mDelta
mar. 10/148:15 amSCL - CLT
2 stops16h 39mDelta
Deal found 4/1$754
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/157:46 pmGSP - SCL
1 stop11h 19mAmerican Airlines
lun. 10/2711:45 pmSCL - GSP
1 stop16h 47mAmerican Airlines
Deal found 4/2$754
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/155:05 pmGSP - SCL
2 stops20h 20mDelta
dom. 10/2612:25 amSCL - GSP
2 stops20h 52mDelta
Deal found 4/2$794
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/161:10 pmCLT - SCL
1 stop17h 35mLATAM Airlines
jue. 6/268:40 pmSCL - CLT
1 stop14h 20mLATAM Airlines
Deal found 3/31$796
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/228:18 pmSAV - SCL
1 stop10h 47mAmerican Airlines
mié. 10/2911:45 pmSCL - SAV
1 stop23h 03mAmerican Airlines
Deal found 4/1$804
This Mytrip deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/309:05 amCHS - SCL
3 stops36h 10mMultiple Airlines
sáb. 5/312:30 amSCL - CHS
2 stops33h 06mMultiple Airlines
Deal found 4/1$847
This eDestinos deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/117:20 amCHS - SCL
2 stops22h 20mLATAM Airlines
dom. 7/2711:25 pmSCL - CHS
2 stops19h 32mLATAM Airlines
Deal found 4/1$869
This LATAM Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/227:00 amSAV - SCL
2 stops30h 30mLATAM Airlines
mar. 10/79:40 pmSCL - SAV
1 stop22h 04mLATAM Airlines
Deal found 4/1$874
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/115:55 pmCHS - SCL
1 stop13h 05mDelta
dom. 7/2711:25 pmSCL - CHS
2 stops21h 18mDelta
Deal found 4/1$904
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/2110:32 amCHS - SCL
1 stop20h 23mAmerican Airlines
mié. 5/289:00 pmSCL - CHS
1 stop12h 52mAmerican Airlines
Deal found 4/1$913

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 2, 2025.
Use the filters below to find and compare flights from South Carolina to Santiago that are best for you.

Fly from

South Carolina

Fly to

Santiago

Route

Depart

Return

Price

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

jue. 5/1

10:57 am-4:35 am

2 stops17h 38m

Santiago Arturo Merino Benitez

jue. 5/8

2:30 pm-11:03 am

2 stops20h 33m

$690

Myrtle BeachSantiago

MYR - SCL

MYRSCL

Myrtle Beach Intl

lun. 5/12

6:00 am-4:15 am

2 stops22h 15m

Santiago Arturo Merino Benitez

mar. 5/27

11:55 pm-9:05 pm

2 stops21h 10m

$698

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

lun. 6/16

6:00 pm-7:00 am

1 stop13h 00m

Santiago Arturo Merino Benitez

lun. 6/23

8:40 pm-8:57 am

1 stop12h 17m

$796

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

lun. 6/16

11:24 am-7:00 am

1 stop19h 36m

Santiago Arturo Merino Benitez

jue. 6/26

11:25 pm-8:30 pm

2 stops21h 05m

$804

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

mié. 4/30

9:05 am-9:15 pm

3 stops36h 10m

Santiago Arturo Merino Benitez

sáb. 5/3

12:30 am-9:36 am

2 stops33h 06m

$847

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

vie. 7/11

7:20 am-5:40 am

2 stops22h 20m

Santiago Arturo Merino Benitez

dom. 7/27

11:25 pm-6:57 pm

2 stops19h 32m

$869

SavannahSantiago

SAV - SCL

SAVSCL

Savannah/Hilton Head

lun. 9/22

7:00 am-2:30 pm

2 stops30h 30m

Santiago Arturo Merino Benitez

mar. 10/7

9:40 pm-6:44 pm

1 stop22h 04m

$874

SavannahSantiago

SAV - SCL

SAVSCL

Savannah/Hilton Head

mar. 9/23

8:14 pm-8:05 am

1 stop10h 51m

Santiago Arturo Merino Benitez

mar. 10/7

9:55 pm-9:06 pm

1 stop24h 11m

$885

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

vie. 7/11

5:55 pm-7:00 am

1 stop13h 05m

Santiago Arturo Merino Benitez

dom. 7/27

11:25 pm-8:43 pm

2 stops21h 18m

$904

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

mié. 5/21

10:32 am-6:55 am

1 stop20h 23m

Santiago Arturo Merino Benitez

mié. 5/28

9:00 pm-9:52 am

1 stop12h 52m

$913

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 21 results
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Best time to book a flight from South Carolina to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Santiago

What is the cheapest month to book a flight from South Carolina to Santiago?

Currently, April is the cheapest month in which you can book a flight from South Carolina to Santiago (average of $752). Flying from South Carolina to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SCL?

Find hourly flight availability from South Carolina to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 2, 2025.

When flying from South Carolina to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated abril 2, 2025.
To help decide which airline to fly from South Carolina to Santiago, see what other customers have to say about Delta, Copa Airlines and LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Crew

8.5

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,899 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Crew

8.5

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,400 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Crew

8.5

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,754 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Crew

8.5

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Qantas Airways
7.5
Good
813 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Crew

8.5

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Crew

8.5

Overall

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from South Carolina?

    For a flight from South Carolina to Santiago, you will be flying into Arturo Merino Benitez. Santiago Arturo Merino Benitez (SCL) is just 8.4 mi from the center of the city.

  • What are the most popular routes from South Carolina to Santiago?

    The most popular flight routes from South Carolina to Santiago are Charlotte Douglas - Santiago Arturo Merino Benitez, Savannah/Hilton Head - Santiago Arturo Merino Benitez and Charleston - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from South Carolina to Santiago that include hotel bookings?

    Yes. In addition to deals on South Carolina to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santiago.

  • Can I find deals for business class flights from South Carolina to Santiago?

    Yes. Cheapflights offers flight deals from South Carolina to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Santiago?

    Currently, April is the cheapest month in which you can book a flight from South Carolina to Santiago (average of $752). Flying from South Carolina to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Santiago

Discover the top 2 airlines that operate flights from South Carolina to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$603Average$853FlexibilityNo cancel feeOn-time81%
DeltaCheapest$617Average$947FlexibilityNo cancel feeOn-timeN/A

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