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$361+ Cheap flights from Santo Domingo (SDQ) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/30. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — SCL
Apr 27 — May 41
Sun 4/27
Sun 5/4
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Santiago Arturo Merino Benitez are usually found in May or August, booked 67 days in advance, depart on a Thursday or Tuesday and return on a Monday

Cheap flight deals from Santo Domingo to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 22, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$541
(Priceline)

One-way from

$361
(Copa Airlines)

Popular in

February

Cheapest in

May

Average price

$589
Provider with most accurate pricing for Santo Domingo Las Americas-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Santiago Arturo Merino Benitez flights.
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From Santo Domingo Las Americas to Santiago Arturo Merino Benitez
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One-way flight from Santo Domingo Las Americas to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 17% potential increase in price ($130 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Santo Domingo to Santiago

Cheapest flights from Santo Domingo to Santiago
Explore the most affordable flight options available from Santo Domingo to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

This Priceline deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/66:10 pmSDQ - SCL
1 stop10h 05mAvianca
Fri 6/1311:55 pmSCL - SDQ
1 stop10h 55mAvianca
Deal found 4/22$541
This Copa Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/18:57 amSDQ - SCL
1 stop14h 07mCopa Airlines
Sun 9/73:23 amSCL - SDQ
1 stop13h 54mCopa Airlines
Deal found 4/21$591
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/66:40 pmSDQ - SCL
3 stops33h 21mMultiple Airlines
Fri 6/135:55 amSCL - SDQ
1 stop11h 20mMultiple Airlines
Deal found 4/22$641
This Booking.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/77:59 pmSDQ - SCL
2 stops30h 36mArajet
Thu 7/103:35 amSCL - SDQ
1 stop11h 53mArajet
Deal found 4/21$762
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/26:05 amSDQ - SCL
2 stops24h 55mDelta
Mon 9/811:00 amSCL - SDQ
2 stops27h 47mDelta
Deal found 4/21$2,682
This British Airways deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2312:15 pmSDQ - SCL
2 stops43h 20mBritish Airways
Tue 6/103:00 pmSCL - SDQ
2 stops53h 45mBritish Airways
Deal found 4/20$3,095

Cheapflights Fare Finder

Customize your flight search to find flights from Santo Domingo to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
Use the filters below to find and compare flights from Santo Domingo to Santiago that are best for you.

Fly from

Santo Domingo

Fly to

Santiago

Route

Depart

Return

Price

Santo DomingoSantiago

SDQ - SCL

SDQSCL

Santo Domingo Las Americas

Fri 6/6

6:10 pm-4:15 am

1 stop10h 05m

Santiago Arturo Merino Benitez

Fri 6/13

11:55 pm-10:50 am

1 stop10h 55m

$541

Santo DomingoSantiago

SDQ - SCL

SDQSCL

Santo Domingo Las Americas

Mon 9/1

11:56 am-2:43 am

1 stop14h 47m

Santiago Arturo Merino Benitez

Mon 9/8

12:27 pm-10:27 pm

1 stop11h 00m

$591

Santo DomingoSantiago

SDQ - SCL

SDQSCL

Santo Domingo Las Americas

Fri 6/6

6:40 pm-4:01 am

3 stops33h 21m

Santiago Arturo Merino Benitez

Fri 6/13

5:55 am-5:15 pm

1 stop11h 20m

$641

Santo DomingoSantiago

SDQ - SCL

SDQSCL

Santo Domingo Las Americas

Mon 7/7

7:59 pm-2:35 am

2 stops30h 36m

Santiago Arturo Merino Benitez

Thu 7/10

3:35 am-3:28 pm

1 stop11h 53m

$762

Santo DomingoSantiago

SDQ - SCL

SDQSCL

Santo Domingo Las Americas

Tue 9/2

6:05 am-7:00 am

2 stops24h 55m

Santiago Arturo Merino Benitez

Mon 9/8

11:00 am-1:47 pm

2 stops27h 47m

$2,682

Santo DomingoSantiago

SDQ - SCL

SDQSCL

Santo Domingo Las Americas

Fri 5/23

12:15 pm-7:35 am

2 stops43h 20m

Santiago Arturo Merino Benitez

Tue 6/10

3:00 pm-8:45 pm

2 stops53h 45m

$3,095

Santo DomingoSantiago

SDQ - SCL

SDQSCL

Santo Domingo Las Americas

Wed 4/30

11:51 am-11:11 pm

1 stop11h 20m

$361

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/21

Compare providers for flights from Santo Domingo to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santo Domingo to Santiago in April.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santo Domingo-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santo Domingo-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santo Domingo-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santo Domingo-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santo Domingo to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Santiago

How far ahead should I book a flight from Santo Domingo to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Santiago. Price data was last updated on April 18, 2025.

The best time to book flights from Santo Domingo to Santiago is 67 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santo Domingo to Santiago?

Currently, April is the cheapest month in which you can book a flight from Santo Domingo to Santiago (average of $752). Flying from Santo Domingo to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to SCL?

Find hourly flight availability from Santo Domingo to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.

A simple way to save on the total cost of your ticket is to fly from Santo Domingo to Santiago at noon. If you’re flexible enough to do this you can expect to save up to 32% on your trip compared to booking a flight in the morning.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 22, 2025.
Peruse reviews from past customers who have flown with Delta, Copa Airlines and Avianca from Santo Domingo to Santiago to help guide your decision. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,920 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
Delta
8.0
Very good
7,920 reviews
Delta
8.0
Very good
7,920 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
Copa Airlines
7.5
Good
1,408 reviews
Delta
8.0
Very good
7,920 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
Avianca
6.7
Okay
2,319 reviews
Delta
8.0
Very good
7,920 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
British Airways
6.6
Okay
6,794 reviews
Delta
8.0
Very good
7,920 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santo Domingo to Santiago round-trip?

    According to our current data, Avianca ($541), Copa Airlines ($591), and Arajet ($762) offers the cheapest pricing from Santo Domingo to Santiago. Avianca is 8% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Santo Domingo to Santiago that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Santiago.

  • Can I find deals for business class flights from Santo Domingo to Santiago?

    Yes. Cheapflights offers flight deals from Santo Domingo to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Santo Domingo to Santiago (average of $752). Flying from Santo Domingo to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santo Domingo to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Punta Cana to Santiago flights

Top 3 airlines flying from Santo Domingo to Santiago

Discover the top 3 airlines that operate flights from Santo Domingo to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
ArajetCheapest$229Average$457FlexibilityNo cancel feeOn-timeN/A
AviancaCheapest$348Average$566FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$402Average$649FlexibilityNo cancel feeOn-time70%

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