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$309+ Cheap flights from San Francisco (SFO) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/15. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — SCL
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheapflights Tip: The best prices from San Francisco to Santiago Arturo Merino Benitez are usually found in May or August, booked 3 days in advance, depart on a Wednesday or Monday and return on a Saturday

Cheap flight deals from San Francisco to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 17, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$652
(Copa Airlines)

One-way from

$310
(Copa Airlines)

Popular in

December

Cheapest in

May

Average price

$813
Provider with most accurate pricing for San Francisco-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for San Francisco-Santiago Arturo Merino Benitez flights.
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From San Francisco to Santiago Arturo Merino Benitez
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One-way flight from San Francisco to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 11% potential increase in price ($113 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($42 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from San Francisco to Santiago

Cheapest flights from San Francisco to Santiago
Explore the most affordable flight options available from San Francisco to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Copa Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/151:37 amSFO - SCL
1 stop14h 47mCopa Airlines
Fri 5/234:11 amSCL - SFO
1 stop22h 29mCopa Airlines
Deal found 4/16$652
This eDestinos deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/168:55 amSFO - SCL
1 stop18h 05mMultiple Airlines
Mon 7/148:20 amSCL - SFO
1 stop30h 59mMultiple Airlines
Deal found 4/17$657
This eDestinos deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/177:30 amSFO - SCL
1 stop20h 30mLATAM Airlines
Mon 7/148:40 pmSCL - SFO
1 stop16h 37mLATAM Airlines
Deal found 4/17$663
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/196:15 amSFO - SCL
1 stop21h 45mDelta
Thu 7/108:40 pmSCL - SFO
1 stop25h 12mDelta
Deal found 4/17$664
This Priceline deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1212:05 amSFO - SCL
2 stops25h 10mAvianca
Sat 8/236:10 amSCL - SFO
2 stops20h 45mAvianca
Deal found 4/15$682
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/249:15 amSFO - SCL
2 stops18h 45mAmerican Airlines
Tue 7/19:55 pmSCL - SFO
2 stops23h 58mAmerican Airlines
Deal found 4/17$695
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/212:32 amSFO - SCL
1 stop27h 18mUnited Airlines
Sat 11/1510:45 pmSCL - SFO
1 stop30h 10mUnited Airlines
Deal found 4/16$782
This Aeromexico deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1511:05 pmSFO - SCL
1 stop17h 10mAeromexico
Sun 12/2811:25 pmSCL - SFO
2 stops39h 53mAeromexico
Deal found 4/16$879

Cheapflights Fare Finder

Customize your flight search to find flights from San Francisco to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from San Francisco to Santiago that are best for you.

Fly from

San Francisco

Fly to

Santiago

Route

Depart

Return

Price

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Thu 5/15

1:37 am-7:24 pm

1 stop14h 47m

Santiago Arturo Merino Benitez

Fri 5/23

4:11 am-11:40 pm

1 stop22h 29m

$652

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Mon 6/16

8:55 am-6:00 am

1 stop18h 05m

Santiago Arturo Merino Benitez

Mon 7/14

8:20 am-12:19 pm

1 stop30h 59m

$657

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Tue 6/17

7:30 am-7:00 am

1 stop20h 30m

Santiago Arturo Merino Benitez

Mon 7/14

8:40 pm-10:17 am

1 stop16h 37m

$663

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Thu 6/19

6:15 am-7:00 am

1 stop21h 45m

Santiago Arturo Merino Benitez

Thu 7/10

8:40 pm-6:52 pm

1 stop25h 12m

$664

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Tue 8/12

12:05 am-4:15 am

2 stops25h 10m

Santiago Arturo Merino Benitez

Sat 8/23

6:10 am-11:55 pm

2 stops20h 45m

$682

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Tue 6/24

9:15 am-7:00 am

2 stops18h 45m

Santiago Arturo Merino Benitez

Tue 7/1

9:55 pm-11:13 am

1 stop16h 18m

$695

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Thu 5/15

7:52 pm-7:24 pm

1 stop20h 32m

$309

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Mon 4/28

2:20 pm-1:25 pm

2 stops20h 05m

$328

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Wed 4/30

2:20 pm-1:25 pm

3 stops44h 05m

$334

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Wed 4/30

6:10 am-6:00 am

2 stops20h 50m

$407

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 12 results
1
2

Compare providers for flights from San Francisco to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santiago in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars
SmartFaresPrice Accuracy1 starTrust Score*1 star
CheapfaremartPrice Accuracy-Trust Score*1 star
MytripPrice Accuracy3 starsTrust Score*3 stars
FlightnetworkPrice Accuracy2 starsTrust Score*3 stars
Justfly.comPrice Accuracy3 starsTrust Score*2 stars
CheapOairPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Francisco-Santiago flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on San Francisco-Santiago flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from San Francisco-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Francisco-Santiago flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santiago

How far ahead should I book a flight from San Francisco to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Santiago. Price data was last updated on April 11, 2025.

Booking 3 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Francisco to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Francisco to Santiago?

Currently, April is the cheapest month in which you can book a flight from San Francisco to Santiago (average of $752). Flying from San Francisco to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to SCL?

Find hourly flight availability from San Francisco to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

One of the essential ways to save on airfare from San Francisco to Santiago is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 18% on airfare.

What is the cheapest day to fly from San Francisco to Santiago?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Santiago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Francisco to Santiago flight should consider departing on Tuesday evenings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 17, 2025.
To help decide which airline to fly from San Francisco to Santiago, see what other customers have to say about Delta, Copa Airlines and LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,917 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,409 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,761 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,315 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from San Francisco to Santiago round-trip?

    Currently priced at $652, Copa Airlines will fly you from San Francisco to Santiago and back. In addition to Copa Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from LATAM Airlines and Delta - these airlines can fly you to your destination from $663 and $664, respectively. Copa Airlines is currently priced 25% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from San Francisco to Santiago one-way?

    $310 is the cheapest one-way deal found within the past few days, from Copa Airlines. You may also be able to find cheap deals on Avianca and American Airlines, with prices starting from $327 and $407, respectively.

  • Where are the most common layover locations when flying from San Francisco to Santiago?

    Of the flights from San Francisco to Santiago that have layovers, most of them stop in Los Angeles. San Francisco to Santiago flights stop in Panama City the next most. Houston comes next as the third most popular layover location for San Francisco to Santiago flights.

  • What are some popular things to do or see while on a layover in Los Angeles?

    Hollywood Bowl, Hollywood Walk of Fame, and L.A. Live are currently the most popular points of interest in Los Angeles at the moment. Hollywood Bowl, Hollywood Walk of Fame and L.A. Live are located about 12.5 mi, 11.7 mi, and 10.8 mi, respectively from Los Angeles if you are interested in checking them out. Travelers in need of a car in Los Angeles can rent one for about $39 per day.

  • What are some popular points of interest to see during a layover in Panama City?

    The majority of Panama City visitors spend their time at Panama Old Cathedral, Amador Causeway, and Panama Canal. Those on a layover in Panama City interested in visiting Panama Old Cathedral, Amador Causeway, or Panama Canal can do so by traveling 13.2 mi, 14.7 mi, and 15.1 mi, respectively from Panama City Tocumen Intl. Those looking to explore during their layover in Panama City can rent a car from Panama City Tocumen Intl for about $14 per day.

  • What are points of interest worth seeing during a layover in Houston?

    Most Houston visitors opt to spend their time at Space Center Houston, House of Blues Houston, and Revention Music Center. Space Center Houston, House of Blues Houston, and Revention Music Center can be accessed by traveling approximately 33.5 mi, 16.1 mi, and 15.5 mi, respectively from Houston George Bush Intcntl. Travelers can book a car rental at Houston George Bush Intcntl for about $40 per day to make their sightseeing more efficient.

  • Where are the least popular layover locations for San Francisco to Santiago flights?

    The least popular layover on flights from San Francisco to Santiago is Dallas. Atlanta is the second least popular location for layovers on flights from San Francisco to Santiago.

  • Can I find deals for flights from San Francisco to Santiago that include hotel bookings?

    Yes. In addition to deals on San Francisco to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santiago.

  • Can I find deals for business class flights from San Francisco to Santiago?

    Yes. Cheapflights offers flight deals from San Francisco to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Santiago?

    Currently, April is the cheapest month in which you can book a flight from San Francisco to Santiago (average of $752). Flying from San Francisco to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Francisco to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from San Francisco to Santiago

Discover the top 7 airlines that operate flights from San Francisco to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$473Average$614FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$537Average$786FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$622Average$848FlexibilityNo cancel feeOn-time69%
DeltaCheapest$642Average$861FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$658Average$932FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$659Average$944FlexibilityNo cancel feeOn-time81%
AeromexicoCheapest$765Average$922FlexibilityNo cancel feeOn-timeN/A

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