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$243+ Cheap flights from Quito (UIO) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel.
UIO — SCL
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheapflights Tip: The best prices from Quito Mariscal Sucr to Santiago Arturo Merino Benitez are usually found in March or June, booked 39 days in advance, depart on a Monday or Friday and return on a Friday

Cheap flight deals from Quito to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Quito (UIO) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$401
(Booking.com)

One-way from

$243
(Priceline)

Popular in

February

Cheapest in

March

Average price

$364
Provider with most accurate pricing for Quito Mariscal Sucr-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Quito Mariscal Sucr-Santiago Arturo Merino Benitez flights.
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From Quito Mariscal Sucr to Santiago Arturo Merino Benitez
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One-way flight from Quito Mariscal Sucr to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 4% potential increase in price ($16 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Quito to Santiago

Cheapest flights from Quito to Santiago
Explore the most affordable flight options available from Quito to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This CheapOair deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/44:41 pmUIO - SCL
1 stop10h 20mJetSMART
Sat 8/99:01 pmSCL - UIO
1 stop20h 13mJetSMART
Deal found 4/17$396
This Priceline deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/286:00 amUIO - SCL
2 stops15h 30mAvianca
Wed 5/285:55 amSCL - UIO
1 stop12h 10mAvianca
Deal found 4/16$417
This Booking.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/302:20 amUIO - SCL
1 stop10h 00mMultiple Airlines
Sun 11/96:01 amSCL - UIO
1 stop11h 43mMultiple Airlines
Deal found 4/17$441
This Copa Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/173:22 amUIO - SCL
1 stop18h 32mCopa Airlines
Sat 11/224:19 amSCL - UIO
1 stop15h 20mCopa Airlines
Deal found 4/17$463
This Booking.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/118:35 amUIO - SCL
2 stops17h 55mLATAM Airlines
Sun 5/254:55 pmSCL - UIO
2 stops19h 45mLATAM Airlines
Deal found 4/17$533
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/151:35 amUIO - SCL
1 stop29h 15mUnited Airlines
Sat 11/2210:45 pmSCL - UIO
1 stop27h 45mUnited Airlines
Deal found 4/17$3,963

Cheapflights Fare Finder

Customize your flight search to find flights from Quito to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Quito to Santiago that are best for you.

Fly from

Quito

Fly to

Santiago

Route

Depart

Return

Price

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Mon 8/4

4:41 pm-4:01 am

1 stop10h 20m

Santiago Arturo Merino Benitez

Sat 8/9

9:01 pm-4:14 pm

1 stop20h 13m

$396

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Mon 4/28

6:00 am-10:30 pm

2 stops15h 30m

Santiago Arturo Merino Benitez

Wed 5/28

5:55 am-5:05 pm

1 stop12h 10m

$417

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Sun 5/11

4:56 pm-4:01 am

1 stop10h 05m

Santiago Arturo Merino Benitez

Sat 5/24

12:30 am-11:40 am

1 stop12h 10m

$466

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Sun 9/14

3:07 am-12:04 am

1 stop18h 57m

Santiago Arturo Merino Benitez

Tue 9/30

1:23 am-5:31 pm

1 stop18h 08m

$484

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Sun 5/11

8:35 am-3:30 am

2 stops17h 55m

Santiago Arturo Merino Benitez

Sun 5/25

4:55 pm-11:40 am

2 stops19h 45m

$533

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Sun 8/17

7:45 am-10:30 pm

2 stops13h 45m

$243

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Wed 8/20

4:41 pm-4:01 am

1 stop10h 20m

$279

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Tue 8/19

6:00 am-8:38 pm

1 stop13h 38m

$302

QuitoSantiago

UIO - SCL

UIOSCL

Quito Mariscal Sucr

Fri 5/16

1:30 am-7:24 pm

1 stop16h 54m

$320

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Compare providers for flights from Quito to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Quito to Santiago in April.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Quito-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Quito-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Quito-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Quito-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Quito-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Quito to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Quito with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Quito to Santiago

How far ahead should I book a flight from Quito to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Quito to Santiago. Price data was last updated on April 11, 2025.

The price you pay for your flight from Quito to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 39 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Quito to Santiago?

Currently, April is the cheapest month in which you can book a flight from Quito to Santiago (average of $752). Flying from Quito to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from UIO to SCL?

Find hourly flight availability from Quito to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 9% on flights from Quito to Santiago by exploring options for tickets at noon.

What is the cheapest day to fly from Quito to Santiago?

Use this chart to determine the cheapest time to fly round-trip from Quito to Santiago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Quito to Santiago flight should consider departing on Monday at noon when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 17, 2025.
To help decide which airline to fly from Quito to Santiago, see what other customers have to say about Copa Airlines, LATAM Airlines and Avianca. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,409 reviews

Crew

8.1

Entertainment

6.8

Overall

7.6

Food

6.8

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.
Copa Airlines
7.6
Good
1,409 reviews
Copa Airlines
7.6
Good
1,409 reviews

Crew

8.1

Entertainment

6.8

Overall

7.6

Food

6.8

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.
LATAM Airlines
7.5
Good
1,761 reviews
Copa Airlines
7.6
Good
1,409 reviews

Crew

8.1

Entertainment

6.8

Overall

7.6

Food

6.8

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.
Avianca
6.7
Okay
2,315 reviews
Copa Airlines
7.6
Good
1,409 reviews

Crew

8.1

Entertainment

6.8

Overall

7.6

Food

6.8

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.
JetSMART
6.6
Okay
182 reviews
Copa Airlines
7.6
Good
1,409 reviews

Crew

8.1

Entertainment

6.8

Overall

7.6

Food

6.8

Comfort

7.4

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Related info for your journey

Find useful and relevant information for your journey from Quito to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Quito to Santiago round-trip?

    Currently priced at $417, Avianca will fly you from Quito to Santiago and back. In addition to Avianca, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from JetSMART and Copa Airlines - these airlines can fly you to your destination from $450 and $504, respectively.

  • What are the cheapest airlines to fly from Quito to Santiago one-way?

    The cheapest airlines for a one-way flight from Quito to Santiago are Avianca ($243), JetSMART ($249), and Copa Airlines ($257).

  • Can I find deals for flights from Quito to Santiago that include hotel bookings?

    Yes. In addition to deals on Quito to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Quito to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Quito to Santiago.

  • Can I find deals for business class flights from Quito to Santiago?

    Yes. Cheapflights offers flight deals from Quito to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Quito to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Quito to Santiago (average of $752). Flying from Quito to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Quito to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Guayaquil to Santiago flights

Top 3 airlines flying from Quito to Santiago

Discover the top 3 airlines that operate flights from Quito to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$207Average$419FlexibilityNo cancel feeOn-time71%
JetSMARTCheapest$214Average$365FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$306Average$455FlexibilityNo cancel feeOn-time81%

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