HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santiago

$292+ Cheap flights from Panama City (PTY) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SCL
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Panama City Tocumen Intl to Santiago Arturo Merino Benitez are usually found in August or May, booked 20 days in advance, depart on a Sunday or Thursday and return on a Tuesday

Cheap flight deals from Panama City to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$547
(Priceline)

One-way from

$292
(Priceline)

Popular in

January

Cheapest in

August

Average price

$553

Good round-trip deal

$522 or less
Provider with most accurate pricing for Panama City Tocumen Intl-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Santiago Arturo Merino Benitez flights.
Search Deals
From Panama City Tocumen Intl to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Panama City Tocumen Intl to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($59 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals
Price to beat on a round-trip flight from Panama City Tocumen Intl to Santiago Arturo Merino Benitez.
Search Deals

Find flight deals from Panama City to Santiago

Cheapest flights from Panama City to Santiago
Explore the most affordable flight options available from Panama City to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Priceline deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/43:20 amPTY - SCL
1 stop9h 05mAvianca
Mon 6/91:55 amSCL - PTY
1 stop13h 45mAvianca
Deal found 4/17$547
This Copa Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/183:08 pmPTY - SCL
Nonstop6h 36mCopa Airlines
Sun 6/222:24 amSCL - PTY
Nonstop6h 52mCopa Airlines
Deal found 4/17$562
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/43:20 amPTY - SCL
2 stops33h 05mMultiple Airlines
Tue 6/109:35 pmSCL - PTY
2 stops24h 35mMultiple Airlines
Deal found 4/17$698
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1810:00 amPTY - SCL
3 stops44h 50mUnited Airlines
Sun 11/2310:45 pmSCL - PTY
2 stops46h 04mUnited Airlines
Deal found 4/17$1,815
This Iberia deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/221:50 pmPTY - SCL
2 stops40h 30mIberia
Wed 10/18:00 pmSCL - PTY
2 stops66h 25mIberia
Deal found 4/17$4,034

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Panama City to Santiago that are best for you.

Fly from

Panama City

Fly to

Santiago

Route

Depart

Return

Price

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Wed 6/4

3:20 am-1:25 pm

1 stop9h 05m

Santiago Arturo Merino Benitez

Mon 6/9

1:55 am-2:40 pm

1 stop13h 45m

$547

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Wed 6/18

3:08 pm-10:44 pm

Nonstop6h 36m

Santiago Arturo Merino Benitez

Sun 6/22

2:24 am-8:16 am

Nonstop6h 52m

$562

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Wed 6/4

3:20 am-1:25 pm

2 stops33h 05m

Santiago Arturo Merino Benitez

Tue 6/10

9:35 pm-9:10 pm

2 stops24h 35m

$698

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Mon 9/22

1:50 pm-8:20 am

2 stops40h 30m

Santiago Arturo Merino Benitez

Wed 10/1

8:00 pm-12:25 pm

2 stops66h 25m

$4,034

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Tue 6/24

3:20 am-1:25 pm

1 stop9h 05m

$292

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Tue 6/24

3:20 am-9:15 pm

2 stops16h 55m

$408

Panama CitySantiago

PTY - SCL

PTYSCL

Panama City Tocumen Intl

Thu 4/24

9:28 pm-5:04 am

Nonstop6h 36m

$1,051

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Compare providers for flights from Panama City to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Santiago in April.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Santiago

How far ahead should I book a flight from Panama City to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Santiago. Price data was last updated on April 11, 2025.

Booking 20 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Panama City to Santiago?

Currently, April is the cheapest month in which you can book a flight from Panama City to Santiago (average of $752). Flying from Panama City to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SCL?

Find hourly flight availability from Panama City to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

It’s optimal to fly from Panama City to Santiago at noon. By choosing this option you can save up to 14% on the cost of your flight, compared to a flight in the afternoon.

Weekly flight availability from Panama City to Santiago

Explore weekly flight availability from Panama City to Santiago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 17, 2025.

The most flights from PTY to SCL are scheduled on a Monday (7 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (7 on average).

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 17, 2025.
Delta
8.0
Very good
7,916 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,916 reviews
Delta
8.0
Very good
7,916 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Copa Airlines
7.6
Good
1,409 reviews
Delta
8.0
Very good
7,916 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Avianca
6.7
Okay
2,316 reviews
Delta
8.0
Very good
7,916 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Panama City to Santiago?

    To fly from Panama City to Santiago, you need to book a flight from Tocumen Intl (PTY) to Arturo Merino Benitez (SCL). Nonstop flights to Santiago Arturo Merino Benitez from Panama City Tocumen Intl take 6h 32m on average. When it comes time to book airfare, you have a few options: there are 7 outbound flights from Tocumen Intl to Arturo Merino Benitez offered by 2 different airlines.

  • How popular is this Panama City to Santiago flight route?

    This flight path from Panama City Tocumen Intl to Santiago Arturo Merino Benitez was viewed by 6 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Panama City to Santiago round-trip?

    Cheapflights users have booked flights from Panama City to Santiago round-trip from $547. Other airlines that can offer you cheap pricing are Copa Airlines, from $562, and Delta, from $19,897.

  • What are the most reliable airlines from Panama City to Santiago?

    Consider Turkish Airlines (93%), KLM (82%) or Copa Airlines (79%) when booking your flight. These represent the most reliable airlines when flying from Panama City to Santiago.

  • What are the cheapest flights from Panama City to Santiago?

    On average you can expect to pay $557 for a flight from Panama City to Santiago. The cheapest flight overall is $522 while the most popular route, (Panama City Tocumen Intl - Santiago Arturo Merino Benitez) is currently priced at $525.

  • Can I find deals for flights from Panama City to Santiago that include hotel bookings?

    Yes. In addition to deals on Panama City to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Santiago.

  • Can I find deals for business class flights from Panama City to Santiago?

    Yes. Cheapflights offers flight deals from Panama City to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Panama City to Santiago (average of $752). Flying from Panama City to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Santiago car rentals
Santiago Arturo Merino Benitez Airport car rentals
Punta Arenas car rentals
Temuco car rentals
Lastarria car rentals

Top 2 airlines flying from Panama City to Santiago

Discover the top 2 airlines that operate flights from Panama City to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$294Average$442FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$370Average$588FlexibilityNo cancel feeOn-time70%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.