HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santiago

$323+ Cheap flights from Mexico City (MEX) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — SCL
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mexico City to Santiago with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

The best prices from Mexico City Benito Juarez to Santiago Arturo Merino Benitez are usually found in August or April, booked 83 days in advance, depart on a Thursday or Wednesday and return on a Thursday

Cheap flight deals from Mexico City to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$530
(Kiwi.com)

One-way from

$323
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$714

Good round-trip deal

$602 or less

Good one-way deal

$580 or less
Provider with most accurate pricing for Mexico City Benito Juarez-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Santiago Arturo Merino Benitez flights.
Search Deals
From Mexico City Benito Juarez to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Mexico City Benito Juarez to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($54 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2025
Search Deals
Price to beat on a round-trip flight from Mexico City Benito Juarez to Santiago Arturo Merino Benitez.
Search Deals
Price to beat on a one-way flight from Mexico City Benito Juarez to Santiago Arturo Merino Benitez.
Search Deals

Find flight deals from Mexico City to Santiago

Cheapest flights from Mexico City to Santiago
Explore the most affordable flight options available from Mexico City to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/179:45 pmMEX - SCL
1 stop13h 55mMultiple Airlines
Sat 3/296:06 amSCL - MEX
1 stop32h 14mMultiple Airlines
Deal found 2/20$530
This LATAM Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/97:30 pmMEX - SCL
2 stops23h 25mLATAM Airlines
Wed 10/229:30 pmSCL - MEX
1 stop21h 05mLATAM Airlines
Deal found 2/19$534
This Copa Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/225:50 amMEX - SCL
1 stop11h 34mCopa Airlines
Thu 5/2911:28 amSCL - MEX
1 stop14h 47mCopa Airlines
Deal found 2/19$536
This Aeromexico deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/810:05 amMEX - SCL
Nonstop8h 10mAeromexico
Wed 11/1911:25 pmSCL - MEX
Nonstop8h 35mAeromexico
Deal found 2/19$542
This Avianca deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/92:00 pmMEX - SCL
1 stop12h 15mAvianca
Thu 5/292:30 pmSCL - MEX
1 stop14h 35mAvianca
Deal found 2/20$558

Find flights from Mexico City to Santiago within your budget

Customize your flight search to find flights from Mexico City to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Mexico City

Fly to

Santiago

Route

Depart

Return

Price

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Mon 3/17

9:45 pm-2:40 pm

1 stop13h 55m

Santiago Arturo Merino Benitez

Sat 3/29

6:06 am-11:20 am

1 stop32h 14m

$530

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Thu 5/22

5:50 am-7:24 pm

1 stop11h 34m

Santiago Arturo Merino Benitez

Thu 5/29

11:28 am-12:15 am

1 stop14h 47m

$536

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Sun 7/27

8:20 pm-6:40 am

Nonstop8h 20m

Santiago Arturo Merino Benitez

Mon 8/4

8:20 am-2:55 pm

Nonstop8h 35m

$552

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Fri 5/9

2:00 pm-4:15 am

1 stop12h 15m

Santiago Arturo Merino Benitez

Thu 5/29

2:30 pm-3:05 am

1 stop14h 35m

$558

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Sun 3/16

10:10 am-9:15 pm

Nonstop8h 05m

Santiago Arturo Merino Benitez

Fri 3/28

11:15 pm-4:46 am

Nonstop8h 31m

$768

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Sat 5/24

10:05 pm-1:45 pm

1 stop13h 40m

$323

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Tue 5/27

4:55 am-10:30 pm

1 stop15h 35m

$354

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Tue 5/27

8:20 pm-6:25 am

Nonstop8h 05m

$545

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Wed 3/5

2:00 am-8:19 pm

1 stop15h 19m

$560

Mexico CitySantiago

MEX - SCL

MEXSCL

Mexico City Benito Juarez

Tue 3/25

10:10 am-9:15 pm

Nonstop8h 05m

$563

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 12 results
1
2
  • Most accurate provider: When it comes to deals on Mexico City-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Mexico City-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Mexico City-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Mexico City-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Mexico City-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Mexico City to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Mexico City to Santiago

Get recent, data-driven insights about flights from Mexico City to Santiago including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Mexico City to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Mexico City to Santiago. Price data was last updated on February 14, 2025.

The best time to book flights from Mexico City to Santiago is 83 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Mexico City to Santiago?

Currently, April is the cheapest month in which you can book a flight from Mexico City to Santiago (average of $752). Flying from Mexico City to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MEX to SCL?

Find hourly flight availability from Mexico City to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

When flying from Mexico City to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 27% versus a flight in the evening.

What is the cheapest day to fly from Mexico City to Santiago?

Use this chart to determine the cheapest time to fly round-trip from Mexico City to Santiago. Price data was last updated on February 16, 2025.

Travelers seeking maximum savings on their Mexico City to Santiago flight should consider departing on Sunday mornings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Mexico City to Santiago

Explore weekly flight availability from Mexico City to Santiago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 20, 2025.

The most flights from MEX to SCL are scheduled on a Monday (3 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated February 20, 2025.
Read through reviews of airlines operating flights from Mexico City to Santiago, such as Copa Airlines, LATAM Airlines and Aeromexico. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,510 reviews

Crew

8.1

Comfort

7.4

Entertainment

6.9

Overall

7.6

Boarding

7.8

Food

6.9

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Copa Airlines
7.6
Good
1,510 reviews
Copa Airlines
7.6
Good
1,510 reviews

Crew

8.1

Comfort

7.4

Entertainment

6.9

Overall

7.6

Boarding

7.8

Food

6.9

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

LATAM Airlines
7.5
Good
1,795 reviews
Copa Airlines
7.6
Good
1,510 reviews

Crew

8.1

Comfort

7.4

Entertainment

6.9

Overall

7.6

Boarding

7.8

Food

6.9

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Aeromexico
7.5
Good
1,771 reviews
Copa Airlines
7.6
Good
1,510 reviews

Crew

8.1

Comfort

7.4

Entertainment

6.9

Overall

7.6

Boarding

7.8

Food

6.9

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Qantas Airways
7.4
Good
814 reviews
Copa Airlines
7.6
Good
1,510 reviews

Crew

8.1

Comfort

7.4

Entertainment

6.9

Overall

7.6

Boarding

7.8

Food

6.9

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

United Airlines
7.4
Good
8,766 reviews
Copa Airlines
7.6
Good
1,510 reviews

Crew

8.1

Comfort

7.4

Entertainment

6.9

Overall

7.6

Boarding

7.8

Food

6.9

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Mexico City to Santiago?

    If you wish to fly to Santiago from Mexico City, then you need to book flights from Mexico City Benito Juarez to Santiago Arturo Merino Benitez. There are 2 flights from Benito Juarez (MEX) to Arturo Merino Benitez (SCL) per day to choose from. Flights to Santiago from Benito Juarez are available from 4 different airlines, which means you should have some options if you want to compare airfare deals. 8h 05m is how long a nonstop flight from Mexico City to Santiago Arturo Merino Benitez typically takes.

  • How popular is this Mexico City to Santiago flight route?

    Within the past month, 5 users have taken a look at flights from Mexico City Benito Juarez to Santiago Arturo Merino Benitez.

  • What are the cheapest airlines flying from Mexico City to Santiago round-trip?

    Cheapflights users have booked flights from Mexico City to Santiago round-trip from $536. Other airlines that can offer you cheap pricing are LATAM Airlines, from $552, and Avianca, from $558. Users have found that Copa Airlines is 14% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Mexico City to Santiago one-way?

    To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $354. LATAM Airlines flights start at $545 while deals on Copa Airlines start at $560 one-way.

  • What are the most reliable airlines from Mexico City to Santiago?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Mexico City to Santiago on time: LATAM Airlines (95%), Aeromexico (94%), WestJet (94%).

  • What are the cheapest flights from Mexico City to Santiago?

    While on average a flight from Mexico City to Santiago is generally $717, our data shows the cheapest flight currently is $544. When looking at the most popular route, (Mexico City Benito Juarez - Santiago Arturo Merino Benitez), you can expect to pay $536 for that flight.

  • Can I find deals for flights from Mexico City to Santiago that include hotel bookings?

    Yes. In addition to deals on Mexico City to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Santiago.

  • Can I find deals for business class flights from Mexico City to Santiago?

    Yes. Cheapflights offers flight deals from Mexico City to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Mexico City to Santiago (average of $752). Flying from Mexico City to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Santiago car rentals
Santiago Arturo Merino Benitez Airport car rentals
Punta Arenas car rentals
Temuco car rentals
Lastarria car rentals

Top 4 airlines flying from Mexico City to Santiago

Discover the top 4 airlines that operate flights from Mexico City to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$342Average$648FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$347Average$683FlexibilityNo cancel feeOn-time70%
AviancaCheapest$364Average$588FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$516Average$671FlexibilityNo cancel feeOn-time81%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.