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$74+ Cheap flights from Mendoza (MDZ) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
MDZ — SCL
Apr 27 — May 41
Sun 4/27
Sun 5/4
1 adult, Economy
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Cheapflights Tip: The best prices from Mendoza El Plumerillo to Santiago Arturo Merino Benitez are usually found in October or November, booked 67 days in advance, depart on a Wednesday or Thursday and return on a Monday

Cheap flight deals from Mendoza to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Mendoza (MDZ) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 22, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$101
(Kiwi.com)

One-way from

$75
(Kiwi.com)

Popular in

January

Cheapest in

October

Average price

$131

Good round-trip deal

$148 or less

Good one-way deal

$80 or less
Provider with most accurate pricing for Mendoza El Plumerillo-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Mendoza El Plumerillo-Santiago Arturo Merino Benitez flights.
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From Mendoza El Plumerillo to Santiago Arturo Merino Benitez
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One-way flight from Mendoza El Plumerillo to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 5% potential increase in price ($6 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Mendoza El Plumerillo to Santiago Arturo Merino Benitez.
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Price to beat on a one-way flight from Mendoza El Plumerillo to Santiago Arturo Merino Benitez.
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Find flight deals from Mendoza to Santiago

Cheapest flights from Mendoza to Santiago
Explore the most affordable flight options available from Mendoza to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/265:00 pmMDZ - SCL
Nonstop0h 56mJetSMART
Fri 6/277:26 pmSCL - MDZ
Nonstop1h 04mJetSMART
Deal found 4/22$101
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/116:35 pmMDZ - SCL
Nonstop0h 56mMultiple Airlines
Sun 8/31:30 pmSCL - MDZ
Nonstop1h 10mMultiple Airlines
Deal found 4/22$109
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/253:40 pmMDZ - SCL
Nonstop1h 01mSky Airline
Thu 5/86:05 pmSCL - MDZ
Nonstop1h 05mSky Airline
Deal found 4/21$127
This LATAM Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/87:40 pmMDZ - SCL
Nonstop1h 04mLATAM Airlines
Mon 9/85:53 pmSCL - MDZ
Nonstop1h 07mLATAM Airlines
Deal found 4/22$169
This FlightHub deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/212:40 pmMDZ - SCL
Nonstop1h 05mAerolineas Argentinas
Mon 11/36:05 pmSCL - MDZ
1 stop15h 45mAerolineas Argentinas
Deal found 4/22$266

Cheapflights Fare Finder

Customize your flight search to find flights from Mendoza to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
Use the filters below to find and compare flights from Mendoza to Santiago that are best for you.

Fly from

Mendoza

Fly to

Santiago

Route

Depart

Return

Price

MendozaSantiago

MDZ - SCL

MDZSCL

Mendoza El Plumerillo

Thu 6/26

5:00 pm-4:56 pm

Nonstop0h 56m

Santiago Arturo Merino Benitez

Fri 6/27

7:26 pm-9:30 pm

Nonstop1h 04m

$101

MendozaSantiago

MDZ - SCL

MDZSCL

Mendoza El Plumerillo

Fri 7/11

6:35 pm-6:31 pm

Nonstop0h 56m

Santiago Arturo Merino Benitez

Thu 9/11

11:35 am-12:45 pm

Nonstop1h 10m

$109

MendozaSantiago

MDZ - SCL

MDZSCL

Mendoza El Plumerillo

Sat 5/24

9:00 pm-9:01 pm

Nonstop1h 01m

Santiago Arturo Merino Benitez

Wed 6/18

6:05 pm-8:10 pm

Nonstop1h 05m

$127

MendozaSantiago

MDZ - SCL

MDZSCL

Mendoza El Plumerillo

Tue 7/8

7:40 pm-7:44 pm

Nonstop1h 04m

Santiago Arturo Merino Benitez

Fri 8/8

4:33 pm-6:38 pm

Nonstop1h 05m

$169

MendozaSantiago

MDZ - SCL

MDZSCL

Mendoza El Plumerillo

Sun 5/11

2:05 pm-6:20 am

1 stop17h 15m

Santiago Arturo Merino Benitez

Thu 5/15

9:35 pm-6:45 am

1 stop8h 10m

$315

MendozaSantiago

MDZ - SCL

MDZSCL

Mendoza El Plumerillo

Fri 5/2

10:20 pm-10:16 pm

Nonstop0h 56m

$74

MendozaSantiago

MDZ - SCL

MDZSCL

Mendoza El Plumerillo

Tue 5/6

9:00 pm-9:01 pm

Nonstop1h 01m

$82

MendozaSantiago

MDZ - SCL

MDZSCL

Mendoza El Plumerillo

Fri 5/2

8:20 am-5:40 pm

1 stop10h 20m

$108

MendozaSantiago

MDZ - SCL

MDZSCL

Mendoza El Plumerillo

Mon 5/5

11:40 am-6:20 am

1 stop19h 40m

$182

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/21

Compare providers for flights from Mendoza to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Mendoza to Santiago in April.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Mendoza-Santiago flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Mendoza-Santiago flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Mendoza-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Mendoza-Santiago flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Mendoza-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Mendoza to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Mendoza with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mendoza to Santiago

How far ahead should I book a flight from Mendoza to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Mendoza to Santiago. Price data was last updated on April 18, 2025.

The best time to book flights from Mendoza to Santiago is 67 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Mendoza to Santiago?

Currently, April is the cheapest month in which you can book a flight from Mendoza to Santiago (average of $752). Flying from Mendoza to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDZ to SCL?

Find hourly flight availability from Mendoza to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.

One of the essential ways to save on airfare from Mendoza to Santiago is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 22% on airfare.

Weekly flight availability from Mendoza to Santiago

Explore weekly flight availability from Mendoza to Santiago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 22, 2025.

The most flights from MDZ to SCL are scheduled on a Sunday (4 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (1 on average).

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 22, 2025.
Aerolineas Argentinas
8.1
Very good
859 reviews

Overall

8.1

Boarding

8.0

Food

6.4

Comfort

7.5

Entertainment

5.7

Crew

8.3

Reviews

1 / 4
10.0
Excellent

Firuz,Dec 2024

EZE - SLA

Great airline on time and friendly staff. Check-in and boarding even at EZE was easy and straight forward and fast.
Aerolineas Argentinas
8.1
Very good
859 reviews
Aerolineas Argentinas
8.1
Very good
859 reviews

Overall

8.1

Boarding

8.0

Food

6.4

Comfort

7.5

Entertainment

5.7

Crew

8.3

Reviews

1 / 4
10.0
Excellent

Firuz,Dec 2024

EZE - SLA

Great airline on time and friendly staff. Check-in and boarding even at EZE was easy and straight forward and fast.
LATAM Airlines
7.5
Good
1,765 reviews
Aerolineas Argentinas
8.1
Very good
859 reviews

Overall

8.1

Boarding

8.0

Food

6.4

Comfort

7.5

Entertainment

5.7

Crew

8.3

Reviews

1 / 4
10.0
Excellent

Firuz,Dec 2024

EZE - SLA

Great airline on time and friendly staff. Check-in and boarding even at EZE was easy and straight forward and fast.
JetSMART
6.6
Okay
184 reviews
Aerolineas Argentinas
8.1
Very good
859 reviews

Overall

8.1

Boarding

8.0

Food

6.4

Comfort

7.5

Entertainment

5.7

Crew

8.3

Reviews

1 / 4
10.0
Excellent

Firuz,Dec 2024

EZE - SLA

Great airline on time and friendly staff. Check-in and boarding even at EZE was easy and straight forward and fast.

Related info for your journey

Find useful and relevant information for your journey from Mendoza to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Mendoza to Santiago?

    If you wish to fly to Santiago from Mendoza, then you need to book flights from Mendoza El Plumerillo to Santiago Arturo Merino Benitez. There are 2 flights from El Plumerillo (MDZ) to Arturo Merino Benitez (SCL) per day to choose from. Flights to Santiago from El Plumerillo are available from 4 different airlines, which means you should have some options if you want to compare airfare deals. 1h 01m is how long a nonstop flight from Mendoza to Santiago Arturo Merino Benitez typically takes.

  • How popular is this Mendoza to Santiago flight route?

    This flight path from Mendoza El Plumerillo to Santiago Arturo Merino Benitez was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Mendoza to Santiago round-trip?

    Cheapflights users have booked flights from Mendoza to Santiago round-trip from $101. Other airlines that can offer you cheap pricing are Sky Airline, from $127, and LATAM Airlines, from $169. Users have found that JetSMART is 24% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Mendoza to Santiago one-way?

    To fly one-way, consider booking your trip with JetSMART, which is currently one of the cheapest options available, starting at $75. Sky Airline flights start at $82 while deals on Aerolineas Argentinas start at $182 one-way.

  • What are the most reliable airlines from Mendoza to Santiago?

    Consider Aerolineas Argentinas (100%), JetSMART (89%) or Sky Airline (89%) when booking your flight. These represent the most reliable airlines when flying from Mendoza to Santiago.

  • What are the cheapest flights from Mendoza to Santiago?

    On average you can expect to pay $486 for a flight from Mendoza to Santiago. The cheapest flight overall is $54 while the most popular route, (Mendoza El Plumerillo - Santiago Arturo Merino Benitez) is currently priced at $149.

  • Can I find deals for flights from Mendoza to Santiago that include hotel bookings?

    Yes. In addition to deals on Mendoza to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mendoza to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mendoza to Santiago.

  • Can I find deals for business class flights from Mendoza to Santiago?

    Yes. Cheapflights offers flight deals from Mendoza to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mendoza to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Mendoza to Santiago (average of $752). Flying from Mendoza to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mendoza to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Ministro Pistarini to Santiago flights
Jorge Newbery to Santiago flights
Cordoba to Santiago flights
Ushuaia to Santiago flights
Ministro Pistarini to Arica flights

Top 4 airlines flying from Mendoza to Santiago

Discover the top 4 airlines that operate flights from Mendoza to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetSMARTCheapest$44Average$122FlexibilityNo cancel feeOn-timeN/A
Aerolineas ArgentinasCheapest$45Average$126FlexibilityNo cancel feeOn-time59%
LATAM AirlinesCheapest$80Average$135FlexibilityNo cancel feeOn-time81%
Sky AirlineCheapest$80Average$115FlexibilityNo cancel feeOn-time73%

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