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$280+ Cheap flights from Louisiana to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/28. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — SCL
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Louisiana to Santiago

Cheapest flights from Louisiana to Santiago
Explore the most affordable flight options available from Louisiana to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This CheapOair deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:15 amMSY - SCL
1 stop20h 55mLATAM Airlines
Sat 1/1010:15 pmSCL - MSY
2 stops37h 31mLATAM Airlines
Deal found 12/10$1,423
This LATAM Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:37 pmMSY - SCL
2 stops32h 58mLATAM Airlines
Sat 1/1010:35 amSCL - MSY
2 stops27h 10mLATAM Airlines
Deal found 12/10$1,469
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:50 amMSY - SCL
1 stop24h 35mAmerican Airlines
Sat 1/1011:55 pmSCL - MSY
1 stop21h 18mAmerican Airlines
Deal found 12/9$1,666
This Cheapflightsfares deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2010:46 amMSY - SCL
1 stop17h 54mLATAM Airlines
Sun 1/49:30 pmSCL - MSY
1 stop22h 20mLATAM Airlines
Deal found 12/11$1,728
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/103:56 pmMSY - SCL
1 stop13h 54mUnited Airlines
Sat 1/1010:45 pmSCL - MSY
1 stop15h 07mUnited Airlines
Deal found 12/10$1,774

Find flight deals from Louisiana to Santiago

Keep the following information in mind while searching for Louisiana to Santiago flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$642
(LATAM Airlines)

One-way from

$280
(Avianca Connect)

Popular in

June

Cheapest in

May

Average price

$1,228
Provider with most accurate pricing for New Orleans Louis Armstrong-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for New Orleans Louis Armstrong-Santiago Arturo Merino Benitez flights.
Search Deals
From Louisiana to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Louisiana to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($360 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 18% potential price decrease ($183 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisiana to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Louisiana to Santiago that are best for you.

Fly from

Louisiana

Fly to

Santiago

Route

Depart

Return

Price

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Mon 1/26

11:55 am-8:50 am

1 stop17h 55m

Santiago Arturo Merino Benitez

Thu 1/29

10:45 pm-10:52 am

1 stop15h 07m

$924

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Mon 12/22

6:15 am-6:10 am

1 stop20h 55m

Santiago Arturo Merino Benitez

Sat 1/10

10:15 pm-8:46 am

2 stops37h 31m

$1,423

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Mon 12/22

5:50 am-9:25 am

1 stop24h 35m

Santiago Arturo Merino Benitez

Sat 1/10

11:55 pm-6:13 pm

1 stop21h 18m

$1,666

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Sun 12/28

5:05 am-5:30 am

2 stops21h 25m

$280

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Wed 12/24

3:10 pm-5:30 am

3 stops35h 20m

$299

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Thu 12/25

4:58 pm-2:40 pm

3 stops42h 42m

$355

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Wed 12/24

11:17 am-6:10 am

1 stop15h 53m

$541

New OrleansSantiago

MSY - SCL

MSYSCL

New Orleans Louis Armstrong

Sun 12/28

7:20 pm-8:50 am

1 stop34h 30m

$556

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/9

Best time to book a flight from Louisiana to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Louisiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisiana to Santiago

How much does it cost to fly round-trip from Louisiana to Santiago?

Related info for your journey

Find useful and relevant information for your journey from Louisiana to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Louisiana?

    If you book a flight to Santiago from Louisiana, you will be flying to Arturo Merino Benitez, which is the city’s only airport. Santiago Arturo Merino Benitez (SCL) is located 8.4 mi from the center of Santiago.

  • How long is the flight from Louisiana to Santiago?

    Departing from Louisiana to Santiago will take you 17h 55m. The distance from Louisiana to Santiago is about 4557 mi.

  • Can I find deals for flights from Louisiana to Santiago that include hotel bookings?

    Yes. In addition to deals on Louisiana to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisiana to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisiana to Santiago.

  • Can I find deals for business class flights from Louisiana to Santiago?

    Yes. Cheapflights offers flight deals from Louisiana to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Louisiana to Santiago

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Top 2 airlines flying from Louisiana to Santiago

Discover the top 2 airlines that operate flights from Louisiana to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$708Average$883FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$708Average$862FlexibilityNo cancel feeOn-time81%

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