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$543+ Cheap flights from Iowa to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/9. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SCL
Apr 30 — May 71
Wed 4/30
Wed 5/7
1 adult, Economy
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Cheap flight deals from Iowa to Santiago

Keep the following information in mind while searching for Iowa to Santiago flight deals. Data was last updated April 25, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$809
(American Airlines)

One-way from

$543
(LATAM Airlines)
Provider with most accurate pricing for Des Moines-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Santiago Arturo Merino Benitez flights.
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From Iowa to Santiago Arturo Merino Benitez
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One-way flight from Iowa to Santiago Arturo Merino Benitez
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Find flight deals from Iowa to Santiago

Cheapest flights from Iowa to Santiago
Explore the most affordable flight options available from Iowa to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2025.

This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/161:56 pmOMA - SCL
2 stops16h 09mAmerican Airlines
Mon 11/39:30 pmSCL - OMA
2 stops22h 00mAmerican Airlines
Deal found 4/25$809
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/131:10 pmCID - SCL
2 stops16h 55mAmerican Airlines
Wed 9/249:55 pmSCL - CID
2 stops26h 04mAmerican Airlines
Deal found 4/24$848
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1611:05 amOMA - SCL
1 stop18h 55mDelta
Sun 11/212:30 amSCL - OMA
2 stops23h 46mDelta
Deal found 4/25$914
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/75:45 amCID - SCL
2 stops22h 55mDelta
Tue 7/154:55 pmSCL - CID
2 stops31h 00mDelta
Deal found 4/24$914
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/98:09 amDSM - SCL
2 stops21h 51mAmerican Airlines
Mon 6/169:55 pmSCL - DSM
2 stops19h 20mAmerican Airlines
Deal found 4/24$981
This Netflights deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Netflights is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/165:35 amOMA - SCL
2 stops22h 55mLATAM Airlines
Sun 11/212:30 amSCL - OMA
3 stops26h 26mLATAM Airlines
Deal found 4/25$998
This Mytrip deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/86:32 pmDSM - SCL
3 stops34h 08mMultiple Airlines
Sat 6/1412:24 amSCL - DSM
3 stops38h 31mMultiple Airlines
Deal found 4/25$1,008
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/249:08 pmCID - SCL
1 stop31h 42mMultiple Airlines
Thu 6/52:30 pmSCL - CID
2 stops50h 53mMultiple Airlines
Deal found 4/24$1,030
This lastminute.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/92:25 pmDSM - SCL
1 stop15h 35mLATAM Airlines
Mon 6/167:45 amSCL - DSM
2 stops16h 18mLATAM Airlines
Deal found 4/25$1,102
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/92:25 pmDSM - SCL
1 stop15h 35mDelta
Mon 6/164:55 pmSCL - DSM
2 stops18h 44mDelta
Deal found 4/25$1,104
This lastminute.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/98:00 amDSM - SCL
2 stops20h 04mCopa Airlines
Sun 6/1512:13 amSCL - DSM
2 stops18h 46mCopa Airlines
Deal found 4/25$1,570
This Iberia deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/157:30 amCID - SCL
2 stops36h 20mIberia
Thu 9/255:15 pmSCL - CID
2 stops30h 44mIberia
Deal found 4/24$2,188

Cheapflights Fare Finder

Customize your flight search to find flights from Iowa to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2025.
Use the filters below to find and compare flights from Iowa to Santiago that are best for you.

Fly from

Iowa

Fly to

Santiago

Route

Depart

Return

Price

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Tue 9/16

6:55 am-8:05 am

2 stops23h 10m

Santiago Arturo Merino Benitez

Mon 11/3

11:45 pm-6:24 pm

1 stop21h 39m

$809

Cedar RapidsSantiago

CID - SCL

CIDSCL

Cedar Rapids

Sat 9/13

1:10 pm-8:05 am

2 stops16h 55m

Santiago Arturo Merino Benitez

Wed 9/24

9:55 pm-9:59 pm

2 stops26h 04m

$848

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Tue 9/16

11:05 am-8:00 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Sun 11/2

12:30 am-9:16 pm

2 stops23h 46m

$914

Cedar RapidsSantiago

CID - SCL

CIDSCL

Cedar Rapids

Mon 7/7

5:45 am-5:40 am

2 stops22h 55m

Santiago Arturo Merino Benitez

Tue 7/15

4:55 pm-10:55 pm

2 stops31h 00m

$914

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Mon 6/9

8:09 am-7:00 am

2 stops21h 51m

Santiago Arturo Merino Benitez

Mon 6/16

9:55 pm-4:15 pm

2 stops19h 20m

$981

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Tue 9/16

5:35 am-6:30 am

2 stops22h 55m

Santiago Arturo Merino Benitez

Sun 11/2

12:30 am-11:56 pm

3 stops26h 26m

$998

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Sun 6/8

6:32 pm-5:40 am

3 stops34h 08m

Santiago Arturo Merino Benitez

Sat 6/14

12:24 am-1:55 pm

3 stops38h 31m

$1,008

Cedar RapidsSantiago

CID - SCL

CIDSCL

Cedar Rapids

Sat 5/24

9:08 pm-5:50 am

1 stop31h 42m

Santiago Arturo Merino Benitez

Thu 6/5

2:30 pm-4:23 pm

2 stops50h 53m

$1,030

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Mon 6/9

2:25 pm-7:00 am

1 stop15h 35m

Santiago Arturo Merino Benitez

Mon 6/16

7:45 am-11:03 pm

2 stops16h 18m

$1,102

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Mon 6/9

11:24 am-7:00 am

1 stop18h 36m

Santiago Arturo Merino Benitez

Mon 6/16

4:55 pm-10:39 am

2 stops18h 44m

$1,104

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/25

Showing 1-10 of 13 results
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Best time to book a flight from Iowa to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Santiago

What is the cheapest time of day to fly from IA to SCL?

Find hourly flight availability from Iowa to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 25, 2025.

When flying from Iowa to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 25, 2025.
See what other customers who have flown with Delta, Copa Airlines and LATAM Airlines from Iowa to Santiago have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,920 reviews
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,411 reviews
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,767 reviews
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Iberia
7.0
Good
2,686 reviews
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Iowa?

    Most people fly into Santiago Arturo Merino Benitez (SCL) if they book a flight to Santiago from Iowa. Arturo Merino Benitez is conveniently located just 8.4 mi from Santiago’s city center.

  • What are the most popular routes from Iowa to Santiago?

    The most popular flight routes from Iowa to Santiago are Des Moines - Santiago Arturo Merino Benitez, Cedar Rapids - Santiago Arturo Merino Benitez and Omaha Eppley Airfield - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from Iowa to Santiago that include hotel bookings?

    Yes. In addition to deals on Iowa to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Santiago.

  • Can I find deals for business class flights from Iowa to Santiago?

    Yes. Cheapflights offers flight deals from Iowa to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Iowa to Santiago (average of $752). Flying from Iowa to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Iowa to Santiago

Discover the top 2 airlines that operate flights from Iowa to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$735Average$1,277FlexibilityNo cancel feeOn-time71%
DeltaCheapest$782Average$958FlexibilityNo cancel feeOn-timeN/A

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