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$597+ Cheap flights from Houston to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — SCL
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
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Cheap flight deals from Houston to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 31, 2025.

Round-trip from

$597
(Mytrip)

Popular in

December

Cheapest in

March

Average price

$825
From Houston to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($182 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($45 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2025
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Find flight deals from Houston to Santiago

Cheapest flights from Houston to Santiago
Explore the most affordable flight options available from Houston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2912:40 pmIAH - SCL
3 stops31h 35mMultiple Airlines
Tue 5/64:55 amSCL - IAH
2 stops32h 21mMultiple Airlines
Deal found 3/30$597
This Cheapflightsfares deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/172:05 pmIAH - SCL
2 stops22h 20mAvianca
Sun 4/2711:55 pmSCL - IAH
2 stops17h 15mAvianca
Deal found 3/30$627
This Priceline deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:10 pmIAH - SCL
1 stop15h 00mAir Canada
Wed 12/38:50 pmSCL - IAH
1 stop17h 22mAir Canada
Deal found 3/30$1,296
This eDestinos deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2910:22 amHOU - SCL
1 stop19h 38mLATAM Airlines
Sun 6/811:25 pmSCL - HOU
2 stops19h 24mLATAM Airlines
Deal found 3/30$1,332
This LATAM Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/294:59 pmIAH - SCL
1 stop13h 01mLATAM Airlines
Sun 6/811:25 pmSCL - IAH
2 stops25h 34mLATAM Airlines
Deal found 3/30$1,332
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/198:25 pmIAH - SCL
Nonstop9h 25mUnited Airlines
Wed 12/310:45 pmSCL - IAH
Nonstop9h 40mUnited Airlines
Deal found 3/30$1,349
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2810:05 amHOU - SCL
1 stop18h 55mDelta
Tue 12/212:25 amSCL - HOU
2 stops20h 22mDelta
Deal found 3/31$1,364
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/279:40 amIAH - SCL
2 stops19h 00mDelta
Thu 12/411:15 pmSCL - IAH
1 stop14h 49mDelta
Deal found 3/30$1,364
This Aeromexico deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/205:09 pmIAH - SCL
1 stop25h 06mAeromexico
Fri 12/511:25 pmSCL - IAH
1 stop12h 46mAeromexico
Deal found 3/30$1,489
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/224:25 pmHOU - SCL
1 stop12h 25mAmerican Airlines
Sat 12/611:45 pmSCL - HOU
1 stop14h 42mAmerican Airlines
Deal found 3/30$1,494
This Copa Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/169:57 amIAH - SCL
1 stop12h 07mCopa Airlines
Mon 9/221:12 amSCL - IAH
1 stop20h 28mCopa Airlines
Deal found 3/31$1,582
This Trip.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/96:00 amHOU - SCL
2 stops30h 45mMultiple Airlines
Sat 5/1710:10 pmSCL - HOU
2 stops38h 57mMultiple Airlines
Deal found 3/30$1,626

Cheapflights Fare Finder

Customize your flight search to find flights from Houston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from Houston to Santiago that are best for you.

Fly from

Houston

Fly to

Santiago

Route

Depart

Return

Price

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Tue 4/29

12:40 pm-9:15 pm

3 stops31h 35m

Santiago Arturo Merino Benitez

Tue 5/6

4:55 am-12:16 pm

2 stops32h 21m

$597

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 4/17

2:05 pm-1:25 pm

2 stops22h 20m

Santiago Arturo Merino Benitez

Sun 4/27

11:55 pm-4:10 pm

2 stops17h 15m

$627

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Thu 5/29

10:22 am-7:00 am

1 stop19h 38m

Santiago Arturo Merino Benitez

Sun 6/8

11:25 pm-5:49 pm

2 stops19h 24m

$1,332

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 5/29

4:59 pm-7:00 am

1 stop13h 01m

Santiago Arturo Merino Benitez

Sun 6/8

11:25 pm-11:59 pm

2 stops25h 34m

$1,332

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Tue 9/16

4:20 pm-3:00 pm

2 stops20h 40m

Santiago Arturo Merino Benitez

Tue 9/23

5:55 pm-12:12 pm

2 stops20h 17m

$1,364

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Tue 9/16

5:00 pm-8:00 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Mon 9/22

12:25 am-6:58 pm

2 stops20h 33m

$1,364

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Tue 9/16

9:57 am-12:04 am

1 stop12h 07m

Santiago Arturo Merino Benitez

Mon 9/22

1:12 am-7:40 pm

1 stop20h 28m

$1,582

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 5/9

6:00 am-1:45 pm

2 stops30h 45m

Santiago Arturo Merino Benitez

Sat 5/17

10:10 pm-12:07 pm

2 stops38h 57m

$1,626

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Mon 4/21

7:22 am-6:55 am

1 stop22h 33m

Santiago Arturo Merino Benitez

Mon 4/28

9:55 pm-11:16 am

1 stop14h 21m

$1,650

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Fri 5/23

2:28 pm-6:55 am

2 stops15h 27m

Santiago Arturo Merino Benitez

Sun 6/1

9:00 pm-1:58 pm

2 stops17h 58m

$8,238

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/29

Showing 1-10 of 18 results
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Best time to book a flight from Houston to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Santiago

What is the cheapest month to book a flight from Houston to Santiago?

Currently, April is the cheapest month in which you can book a flight from Houston to Santiago (average of $752). Flying from Houston to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from HOU to SCL?

Find hourly flight availability from Houston to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

A simple way to save on the total cost of your ticket is to fly from Houston to Santiago at noon. If you’re flexible enough to do this you can expect to save up to 57% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from Houston to Santiago?

Use this chart to determine the cheapest time to fly round-trip from Houston to Santiago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Houston to Santiago flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated March 31, 2025.
Get a feel of what it's like to fly with Delta, Copa Airlines and LATAM Airlines from Houston to Santiago by reading reviews from past customers. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,899 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,400 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,754 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Qantas Airways
7.5
Good
813 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Houston to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Houston?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Houston. Booking flights from Houston to Arturo Merino Benitez (SCL) should be relatively easy as there are 0 daily inbound flights from Houston from 4 different airlines.

  • What are the cheapest airlines flying from Houston to Santiago round-trip?

    Cheapflights users have booked flights from Houston to Santiago round-trip from $627. Other airlines that can offer you cheap pricing are LATAM Airlines, from $1,332, and Delta, from $1,364. Users have found that Avianca is 53% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Houston to Santiago one-way?

    To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $860. LATAM Airlines flights start at $954 while deals on Copa Airlines start at $3,664 one-way.

  • Can I find deals for flights from Houston to Santiago that include hotel bookings?

    Yes. In addition to deals on Houston to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Santiago.

  • Can I find deals for business class flights from Houston to Santiago?

    Yes. Cheapflights offers flight deals from Houston to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Houston to Santiago (average of $752). Flying from Houston to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Houston to Santiago

Discover the top 4 airlines that operate flights from Houston to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$416Average$735FlexibilityNo cancel feeOn-time71%
American AirlinesCheapest$479Average$1,555FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$892Average$1,403FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$1,337Average$1,532FlexibilityNo cancel feeOn-time69%
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