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$254+ Cheap flights from Houston to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/30. Fares are subject to change and may not be available on all flights or dates of travel.
HOU — SCL
Apr 27 — May 41
Sun 4/27
Sun 5/4
1 adult, Economy
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Cheap flight deals from Houston to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Houston (HO1) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 22, 2025.

Round-trip from

$554
(Priceline)

One-way from

$254
(Priceline)

Popular in

December

Cheapest in

March

Average price

$1,237
From Houston to Santiago Arturo Merino Benitez
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One-way flight from Houston to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 12% potential increase in price ($185 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($45 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Houston to Santiago

Cheapest flights from Houston to Santiago
Explore the most affordable flight options available from Houston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

This Priceline deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/42:05 pmIAH - SCL
2 stops31h 25mAvianca
Sun 9/2112:55 amSCL - IAH
2 stops17h 15mAvianca
Deal found 4/22$554
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/118:57 amIAH - SCL
1 stop19h 53mMultiple Airlines
Mon 5/2611:55 pmSCL - IAH
2 stops20h 33mMultiple Airlines
Deal found 4/21$729
This lastminute.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/126:41 pmHOU - SCL
2 stops16h 44mLATAM Airlines
Wed 6/2511:05 pmSCL - HOU
2 stops19h 50mLATAM Airlines
Deal found 4/22$1,354
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/126:00 amHOU - SCL
2 stops22h 40mDelta
Wed 6/258:40 pmSCL - HOU
1 stop16h 30mDelta
Deal found 4/22$1,364
This FlightHub deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/165:00 pmIAH - SCL
1 stop13h 00mLATAM Airlines
Mon 9/2212:25 amSCL - IAH
2 stops20h 33mLATAM Airlines
Deal found 4/22$1,364
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/281:15 pmIAH - SCL
1 stop16h 45mDelta
Sat 9/64:55 pmSCL - IAH
2 stops22h 54mDelta
Deal found 4/22$1,404
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:20 pmIAH - SCL
Nonstop9h 30mUnited Airlines
Sat 12/1310:45 pmSCL - IAH
Nonstop9h 45mUnited Airlines
Deal found 4/22$1,429
This Aeromexico deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:03 amIAH - SCL
1 stop12h 12mAeromexico
Tue 12/3011:25 pmSCL - IAH
1 stop12h 48mAeromexico
Deal found 4/22$1,489
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/611:05 amIAH - SCL
1 stop18h 55mAmerican Airlines
Sun 6/159:55 pmSCL - IAH
1 stop20h 28mAmerican Airlines
Deal found 4/22$1,519
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:58 amHOU - SCL
1 stop22h 52mAmerican Airlines
Sun 12/2111:45 pmSCL - HOU
1 stop19h 09mAmerican Airlines
Deal found 4/22$1,547
This Copa Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/249:57 amIAH - SCL
1 stop12h 07mCopa Airlines
Sat 11/12:30 amSCL - IAH
1 stop20h 34mCopa Airlines
Deal found 4/21$1,582
This Iberia deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/116:31 pmHOU - SCL
2 stops36h 04mIberia
Fri 5/233:00 pmSCL - HOU
2 stops33h 58mIberia
Deal found 4/21$2,123

Cheapflights Fare Finder

Customize your flight search to find flights from Houston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
Use the filters below to find and compare flights from Houston to Santiago that are best for you.

Fly from

Houston

Fly to

Santiago

Route

Depart

Return

Price

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 9/4

2:05 pm-10:30 pm

2 stops31h 25m

Santiago Arturo Merino Benitez

Sun 9/21

12:55 am-4:10 pm

2 stops17h 15m

$554

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Sun 5/11

8:57 am-5:50 am

1 stop19h 53m

Santiago Arturo Merino Benitez

Mon 5/26

11:55 pm-7:28 pm

2 stops20h 33m

$729

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Thu 6/12

6:41 pm-12:25 pm

2 stops16h 44m

Santiago Arturo Merino Benitez

Wed 6/25

11:05 pm-5:55 pm

2 stops19h 50m

$1,354

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Thu 6/12

6:00 am-5:40 am

2 stops22h 40m

Santiago Arturo Merino Benitez

Wed 6/25

8:40 pm-12:10 pm

1 stop16h 30m

$1,364

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Tue 9/16

9:40 am-4:30 am

2 stops16h 50m

Santiago Arturo Merino Benitez

Tue 9/23

9:40 pm-11:04 am

1 stop15h 24m

$1,364

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 8/28

1:15 pm-7:00 am

1 stop16h 45m

Santiago Arturo Merino Benitez

Sat 9/6

4:55 pm-2:49 pm

2 stops22h 54m

$1,404

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Fri 6/6

11:05 am-7:00 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Sun 6/15

9:55 pm-5:23 pm

1 stop20h 28m

$1,519

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Thu 6/12

2:25 pm-7:24 pm

1 stop27h 59m

Santiago Arturo Merino Benitez

Tue 6/24

12:24 am-12:25 pm

1 stop13h 01m

$1,647

HoustonSantiago

HOU - SCL

HOUSCL

Houston Hobby

Mon 5/12

2:28 pm-6:55 am

2 stops15h 27m

Santiago Arturo Merino Benitez

Fri 5/23

9:00 pm-1:58 pm

2 stops17h 58m

$1,733

HoustonSantiago

IAH - SCL

IAHSCL

Houston George Bush Intcntl

Sun 5/11

9:54 am-1:25 pm

2 stops26h 31m

Santiago Arturo Merino Benitez

Sun 5/25

11:55 pm-7:56 pm

2 stops45h 01m

$1,926

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/21

Showing 1-10 of 18 results
1
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Best time to book a flight from Houston to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Houston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Houston to Santiago

What is the cheapest month to book a flight from Houston to Santiago?

Currently, April is the cheapest month in which you can book a flight from Houston to Santiago (average of $752). Flying from Houston to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from HOU to SCL?

Find hourly flight availability from Houston to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.

A simple way to save on the total cost of your ticket is to fly from Houston to Santiago at noon. If you’re flexible enough to do this you can expect to save up to 57% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from Houston to Santiago?

Use this chart to determine the cheapest time to fly round-trip from Houston to Santiago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Houston to Santiago flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 22, 2025.
Get a feel of what it's like to fly with Delta, LATAM Airlines and Copa Airlines from Houston to Santiago by reading reviews from past customers. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,920 reviews
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,765 reviews
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.5
Good
1,408 reviews
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Air Canada
7.0
Good
9,180 reviews
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Houston to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Houston?

    Located just 8.4 mi from the city center, Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Houston. Booking flights from Houston to Arturo Merino Benitez (SCL) should be relatively easy as there are 0 daily inbound flights from Houston from 4 different airlines.

  • What are the cheapest airlines flying from Houston to Santiago round-trip?

    Cheapflights users have booked flights from Houston to Santiago round-trip from $554. Other airlines that can offer you cheap pricing are LATAM Airlines, from $1,354, and Delta, from $1,364. Users have found that Avianca is 58% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Houston to Santiago one-way?

    To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $254. LATAM Airlines flights start at $979 while deals on American Airlines start at $1,213 one-way.

  • Can I find deals for flights from Houston to Santiago that include hotel bookings?

    Yes. In addition to deals on Houston to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Houston to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Houston to Santiago.

  • Can I find deals for business class flights from Houston to Santiago?

    Yes. Cheapflights offers flight deals from Houston to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Houston to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Houston to Santiago (average of $752). Flying from Houston to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Houston to Santiago

Discover the top 4 airlines that operate flights from Houston to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$416Average$696FlexibilityNo cancel feeOn-time71%
American AirlinesCheapest$479Average$1,529FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$892Average$1,406FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$1,337Average$1,531FlexibilityNo cancel feeOn-time69%

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