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$227+ Cheap flights from Guayaquil (GYE) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — SCL
Apr 20 — Apr 271
Sun 4/20
Sun 4/27
1 adult, Economy
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Cheapflights Tip: The best prices from Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez are usually found in May or August, booked 67 days in advance, depart on a Thursday or Tuesday and return on a Monday

Cheap flight deals from Guayaquil to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

Flightnetwork
3 stars

Round-trip from

$433
(Copa Airlines)

One-way from

$227
(Copa Airlines)

Popular in

February

Cheapest in

May

Average price

$401

Good round-trip deal

$468 or less

Good one-way deal

$302 or less
Provider with most accurate pricing for Guayaquil Jose Joaquin de Olmedo-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Guayaquil Jose Joaquin de Olmedo-Santiago Arturo Merino Benitez flights.
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From Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez
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One-way flight from Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 10% potential increase in price ($44 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez.
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Price to beat on a one-way flight from Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez.
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Find flight deals from Guayaquil to Santiago

Cheapest flights from Guayaquil to Santiago
Explore the most affordable flight options available from Guayaquil to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.

This Copa Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/512:17 pmGYE - SCL
1 stop13h 30mCopa Airlines
Sat 6/711:28 amSCL - GYE
1 stop10h 05mCopa Airlines
Deal found 4/14$433
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/286:31 pmGYE - SCL
1 stop9h 33mMultiple Airlines
Mon 5/59:35 pmSCL - GYE
1 stop14h 35mMultiple Airlines
Deal found 4/14$477
This Booking.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1312:55 pmGYE - SCL
1 stop14h 50mLATAM Airlines
Tue 5/207:30 amSCL - GYE
1 stop7h 45mLATAM Airlines
Deal found 4/15$498
This Priceline deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/245:40 pmGYE - SCL
2 stops18h 45mAvianca
Thu 7/246:10 amSCL - GYE
2 stops16h 23mAvianca
Deal found 4/15$582

Cheapflights Fare Finder

Customize your flight search to find flights from Guayaquil to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2025.
Use the filters below to find and compare flights from Guayaquil to Santiago that are best for you.

Fly from

Guayaquil

Fly to

Santiago

Route

Depart

Return

Price

GuayaquilSantiago

GYE - SCL

GYESCL

Guayaquil Jose Joaquin de Olmedo

Thu 6/5

12:17 pm-2:47 am

1 stop13h 30m

Santiago Arturo Merino Benitez

Sat 6/7

11:28 am-8:33 pm

1 stop10h 05m

$433

GuayaquilSantiago

GYE - SCL

GYESCL

Guayaquil Jose Joaquin de Olmedo

Mon 4/28

6:31 pm-5:04 am

1 stop9h 33m

Santiago Arturo Merino Benitez

Mon 5/5

9:35 pm-11:10 am

1 stop14h 35m

$477

GuayaquilSantiago

GYE - SCL

GYESCL

Guayaquil Jose Joaquin de Olmedo

Tue 5/13

8:40 pm-11:37 am

2 stops13h 57m

Santiago Arturo Merino Benitez

Tue 5/20

7:30 am-2:15 pm

1 stop7h 45m

$498

GuayaquilSantiago

GYE - SCL

GYESCL

Guayaquil Jose Joaquin de Olmedo

Thu 10/9

3:35 am-2:25 pm

1 stop8h 50m

Santiago Arturo Merino Benitez

Fri 10/24

7:10 am-5:55 pm

2 stops12h 45m

$606

GuayaquilSantiago

GYE - SCL

GYESCL

Guayaquil Jose Joaquin de Olmedo

Tue 4/29

4:28 am-11:11 pm

1 stop17h 43m

$227

GuayaquilSantiago

GYE - SCL

GYESCL

Guayaquil Jose Joaquin de Olmedo

Wed 4/23

12:05 pm-4:15 am

2 stops15h 10m

$271

GuayaquilSantiago

GYE - SCL

GYESCL

Guayaquil Jose Joaquin de Olmedo

Wed 4/30

2:45 pm-8:38 pm

Nonstop4h 53m

$274

GuayaquilSantiago

GYE - SCL

GYESCL

Guayaquil Jose Joaquin de Olmedo

Wed 4/30

8:40 pm-1:42 pm

3 stops16h 02m

$338

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/15

Compare providers for flights from Guayaquil to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guayaquil to Santiago in April.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
Trip.comPrice Accuracy1 starTrust Score*3 stars
FlightnetworkPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Guayaquil-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Guayaquil-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Guayaquil-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Guayaquil-Santiago flights, Cheapflights users trust Flightnetwork the most. Flightnetwork has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Guayaquil to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to Santiago

How far ahead should I book a flight from Guayaquil to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Guayaquil to Santiago. Price data was last updated on April 11, 2025.

To ensure you get the cheapest price possible for a flight from Guayaquil to Santiago, you should look to book at least 67 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Guayaquil to Santiago?

Currently, April is the cheapest month in which you can book a flight from Guayaquil to Santiago (average of $752). Flying from Guayaquil to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GYE to SCL?

Find hourly flight availability from Guayaquil to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 15, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 32% on flights from Guayaquil to Santiago by exploring options for tickets in the morning.

What is the cheapest day to fly from Guayaquil to Santiago?

Use this chart to determine the cheapest time to fly round-trip from Guayaquil to Santiago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Guayaquil to Santiago flight should consider departing on Sunday evenings when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Guayaquil to Santiago

Explore weekly flight availability from Guayaquil to Santiago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 15, 2025.

The most flights from GYE to SCL are scheduled on a Monday (1 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 15, 2025.
Read reviews from past customers who have flown Copa Airlines, LATAM Airlines and Avianca from Guayaquil to Santiago. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,408 reviews

Overall

7.6

Comfort

7.4

Crew

8.1

Food

6.8

Entertainment

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
Copa Airlines
7.6
Good
1,408 reviews
Copa Airlines
7.6
Good
1,408 reviews

Overall

7.6

Comfort

7.4

Crew

8.1

Food

6.8

Entertainment

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
LATAM Airlines
7.5
Good
1,758 reviews
Copa Airlines
7.6
Good
1,408 reviews

Overall

7.6

Comfort

7.4

Crew

8.1

Food

6.8

Entertainment

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
Avianca
6.7
Okay
2,313 reviews
Copa Airlines
7.6
Good
1,408 reviews

Overall

7.6

Comfort

7.4

Crew

8.1

Food

6.8

Entertainment

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Guayaquil to Santiago?

    Santiago Arturo Merino Benitez is the airport most travelers will use when flying to Santiago from Guayaquil Jose Joaquin de Olmedo. Booking flights from Jose Joaquin de Olmedo (GYE) to Arturo Merino Benitez (SCL) should be relatively easy as there is 1 daily flight to Santiago from 3 different airlines. 4h 53m is how long a flight from Guayaquil to Santiago Arturo Merino Benitez will take if you book a nonstop flight.

  • How popular is this Guayaquil to Santiago flight route?

    Flights from Guayaquil Jose Joaquin de Olmedo to Santiago Arturo Merino Benitez have been viewed 1 times in the past calendar month.

  • What are the cheapest airlines flying from Guayaquil to Santiago round-trip?

    Copa Airlines, at $433, was found to be the cheapest airline from Guayaquil to Santiago. An alternate airline flying to your destination would be LATAM Airlines.

  • What are the cheapest airlines to fly from Guayaquil to Santiago one-way?

    The cheapest airlines for a one-way flight from Guayaquil to Santiago are Copa Airlines ($227), LATAM Airlines ($274), and Avianca ($295).

  • What are the cheapest flights from Guayaquil to Santiago?

    Looking at all options, your cheapest flight can be booked for $255. While the most popular route (Guayaquil Jose Joaquin de Olmedo - Santiago Arturo Merino Benitez) can be booked for $481 on average our data indicates $1,121 when flying from Guayaquil to Santiago.

  • Can I find deals for flights from Guayaquil to Santiago that include hotel bookings?

    Yes. In addition to deals on Guayaquil to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to Santiago.

  • Can I find deals for business class flights from Guayaquil to Santiago?

    Yes. Cheapflights offers flight deals from Guayaquil to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guayaquil to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Guayaquil to Santiago (average of $752). Flying from Guayaquil to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Guayaquil to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Quito to Santiago flights

Top 3 airlines flying from Guayaquil to Santiago

Discover the top 3 airlines that operate flights from Guayaquil to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetSMARTCheapest$164Average$336FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$249Average$364FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$262Average$435FlexibilityNo cancel feeOn-time81%

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