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$518+ Cheap flights from Greenville (GSP) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SCL
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Greenville to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 17, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$767
(American Airlines)

One-way from

$518
(American Airlines)

Popular in

May

Cheapest in

November

Average price

$883
Provider with most accurate pricing for Greenville-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Greenville-Santiago Arturo Merino Benitez flights.
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From Greenville to Santiago Arturo Merino Benitez
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One-way flight from Greenville to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 9% potential increase in price ($95 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Greenville to Santiago

Cheapest flights from Greenville to Santiago
Explore the most affordable flight options available from Greenville to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/157:46 pmGSP - SCL
1 stop11h 19mAmerican Airlines
Mon 10/2711:45 pmSCL - GSP
1 stop16h 47mAmerican Airlines
Deal found 4/17$754
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/153:42 pmGSP - SCL
1 stop15h 18mDelta
Sun 10/2612:25 amSCL - GSP
2 stops20h 52mDelta
Deal found 4/16$794
This FlightHub deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:55 pmGSP - SCL
1 stop11h 05mLATAM Airlines
Mon 10/1312:25 amSCL - GSP
2 stops21h 56mLATAM Airlines
Deal found 4/17$889
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/311:00 pmGSP - SCL
3 stops24h 25mMultiple Airlines
Sat 6/74:55 amSCL - GSP
3 stops39h 33mMultiple Airlines
Deal found 4/16$1,331

Cheapflights Fare Finder

Customize your flight search to find flights from Greenville to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Greenville to Santiago that are best for you.

Fly from

Greenville

Fly to

Santiago

Route

Depart

Return

Price

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Wed 10/1

11:21 am-8:05 am

2 stops19h 44m

Santiago Arturo Merino Benitez

Tue 10/14

9:55 pm-7:26 pm

1 stop22h 31m

$767

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Wed 10/1

3:42 pm-8:00 am

1 stop15h 18m

Santiago Arturo Merino Benitez

Tue 10/14

9:40 pm-10:56 am

1 stop14h 16m

$794

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Wed 10/1

7:55 pm-8:00 am

1 stop11h 05m

Santiago Arturo Merino Benitez

Mon 10/13

12:25 am-9:21 pm

2 stops21h 56m

$889

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Sat 5/31

1:00 pm-1:25 pm

3 stops24h 25m

Santiago Arturo Merino Benitez

Sat 6/7

4:55 am-8:28 pm

3 stops39h 33m

$1,331

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Thu 5/29

6:18 pm-6:55 am

1 stop12h 37m

$518

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Thu 5/29

4:33 pm-12:25 pm

3 stops43h 52m

$541

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Compare providers for flights from Greenville to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Santiago in April.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*2 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Santiago flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Greenville-Santiago flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Greenville-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Santiago flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Santiago

What is the cheapest month to book a flight from Greenville to Santiago?

Currently, April is the cheapest month in which you can book a flight from Greenville to Santiago (average of $752). Flying from Greenville to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to SCL?

Find hourly flight availability from Greenville to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

It’s typically best to fly out from Greenville to Santiago in the morning. Doing so could potentially save you 13% on the flight price compared to flying at noon, which is usually more expensive.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 17, 2025.
Delta
8.0
Very good
7,917 reviews

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,917 reviews
Delta
8.0
Very good
7,917 reviews

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,761 reviews
Delta
8.0
Very good
7,917 reviews

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,917 reviews

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Greenville to Santiago round-trip?

    Currently priced at $767, American Airlines will fly you from Greenville to Santiago and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and LATAM Airlines - these airlines can fly you to your destination from $794 and $889, respectively. Users have found that American Airlines is 18% cheaper than the other options available to this destination.

  • Can I find deals for flights from Greenville to Santiago that include hotel bookings?

    Yes. In addition to deals on Greenville to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Santiago.

  • Can I find deals for business class flights from Greenville to Santiago?

    Yes. Cheapflights offers flight deals from Greenville to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Greenville to Santiago (average of $752). Flying from Greenville to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Greenville to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Greenville to Santiago

Discover the top 2 airlines that operate flights from Greenville to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$617Average$894FlexibilityNo cancel feeOn-time81%
DeltaCheapest$617Average$1,032FlexibilityNo cancel feeOn-timeN/A

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