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$325+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — SCL
Mar 31 — Apr 71
Mon 3/31
Mon 4/7
1 adult, Economy
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Cheap flight deals from Detroit to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 26, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$603
(Avianca Connect)

One-way from

$325
(Mytrip)

Popular in

June

Cheapest in

November

Average price

$1,063
Provider with most accurate pricing for Detroit Metropolitan Wayne County-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-Santiago Arturo Merino Benitez flights.
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From Detroit Metropolitan Wayne County to Santiago Arturo Merino Benitez
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One-way flight from Detroit Metropolitan Wayne County to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 12% potential increase in price ($165 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($32 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Detroit to Santiago

Cheapest flights from Detroit to Santiago
Explore the most affordable flight options available from Detroit to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2025.

This Avianca Connect deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/76:00 amDTW - SCL
2 stops22h 15mMultiple Airlines
Sun 5/1811:55 pmSCL - DTW
2 stops24h 32mMultiple Airlines
Deal found 3/25$603
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/16:22 pmDTW - SCL
1 stop12h 38mDelta
Thu 7/109:45 amSCL - DTW
1 stop23h 18mDelta
Deal found 3/25$704
This LATAM Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/306:40 amDTW - SCL
2 stops23h 50mLATAM Airlines
Fri 7/118:40 amSCL - DTW
2 stops26h 33mLATAM Airlines
Deal found 3/25$748
This Air Canada deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/14:20 pmDTW - SCL
2 stops21h 05mAir Canada
Sat 11/2912:45 amSCL - DTW
2 stops21h 26mAir Canada
Deal found 3/24$1,377
This Copa Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/27:48 pmDTW - SCL
2 stops27h 20mCopa Airlines
Sat 7/122:23 amSCL - DTW
2 stops31h 50mCopa Airlines
Deal found 3/25$1,549

Cheapflights Fare Finder

Customize your flight search to find flights from Detroit to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Santiago that are best for you.

Fly from

Detroit

Fly to

Santiago

Route

Depart

Return

Price

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 5/7

6:00 am-4:15 am

2 stops22h 15m

Santiago Arturo Merino Benitez

Sun 5/18

11:55 pm-12:27 am

2 stops24h 32m

$603

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Tue 7/1

6:22 pm-7:00 am

1 stop12h 38m

Santiago Arturo Merino Benitez

Tue 7/15

8:40 pm-8:15 pm

1 stop23h 35m

$704

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 6/30

6:40 am-6:30 am

2 stops23h 50m

Santiago Arturo Merino Benitez

Fri 7/11

8:40 am-11:13 am

2 stops26h 33m

$748

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 7/2

7:48 pm-11:08 pm

2 stops27h 20m

Santiago Arturo Merino Benitez

Sat 7/12

2:23 am-10:13 am

2 stops31h 50m

$1,549

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Fri 4/25

3:47 pm-1:25 pm

3 stops21h 38m

$325

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Fri 8/22

8:25 am-6:50 am

1 stop22h 25m

$578

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Fri 8/22

1:53 pm-7:05 am

2 stops17h 12m

$583

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/25

Compare providers for flights from Detroit to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Santiago in March.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Santiago

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Santiago?

Currently, April is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Santiago (average of $752). Flying from Detroit Metropolitan Wayne County Airport to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to SCL?

Find hourly flight availability from Detroit to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 26, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 19% on flights from Detroit Metropolitan Wayne County Airport to Santiago by exploring options for tickets in the evening.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated March 26, 2025.
Delta
8.0
Very good
7,891 reviews

Comfort

8.0

Food

7.3

Overall

8.0

Entertainment

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,891 reviews
Delta
8.0
Very good
7,891 reviews

Comfort

8.0

Food

7.3

Overall

8.0

Entertainment

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,393 reviews
Delta
8.0
Very good
7,891 reviews

Comfort

8.0

Food

7.3

Overall

8.0

Entertainment

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,749 reviews
Delta
8.0
Very good
7,891 reviews

Comfort

8.0

Food

7.3

Overall

8.0

Entertainment

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,891 reviews

Comfort

8.0

Food

7.3

Overall

8.0

Entertainment

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Santiago round-trip?

    According to our current data, Delta ($704), LATAM Airlines ($748), and Copa Airlines ($1,549) offers the cheapest pricing from Detroit Metropolitan Wayne County Airport to Santiago. Users have found that Delta is 39% cheaper than the other options available to this destination.

  • Can I find deals for flights from Detroit to Santiago that include hotel bookings?

    Yes. In addition to deals on Detroit to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Santiago.

  • Can I find deals for business class flights from Detroit to Santiago?

    Yes. Cheapflights offers flight deals from Detroit to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Santiago (average of $752). Flying from Detroit Metropolitan Wayne County Airport to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Detroit to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Detroit to Easter Island flights

Top 4 airlines flying from Detroit to Santiago

Discover the top 4 airlines that operate flights from Detroit to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air CanadaCheapest$789Average$946FlexibilityNo cancel feeOn-time67%
American AirlinesCheapest$822Average$1,106FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$832Average$1,272FlexibilityNo cancel feeOn-time81%
DeltaCheapest$902Average$1,273FlexibilityNo cancel feeOn-timeN/A
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